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Optimizing Bearing Fault Detection:CNN-LSTM with Attentive TabNet for Electric Motor Systems
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作者 Alaa U.Khawaja Ahmad Shaf +4 位作者 Faisal Al Thobiani Tariq Ali Muhammad Irfan Aqib Rehman Pirzada Unza Shahkeel 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第12期2399-2420,共22页
Electric motor-driven systems are core components across industries,yet they’re susceptible to bearing faults.Manual fault diagnosis poses safety risks and economic instability,necessitating an automated approach.Thi... Electric motor-driven systems are core components across industries,yet they’re susceptible to bearing faults.Manual fault diagnosis poses safety risks and economic instability,necessitating an automated approach.This study proposes FTCNNLSTM(Fine-Tuned TabNet Convolutional Neural Network Long Short-Term Memory),an algorithm combining Convolutional Neural Networks,Long Short-Term Memory Networks,and Attentive Interpretable Tabular Learning.The model preprocesses the CWRU(Case Western Reserve University)bearing dataset using segmentation,normalization,feature scaling,and label encoding.Its architecture comprises multiple 1D Convolutional layers,batch normalization,max-pooling,and LSTM blocks with dropout,followed by batch normalization,dense layers,and appropriate activation and loss functions.Fine-tuning techniques prevent over-fitting.Evaluations were conducted on 10 fault classes from the CWRU dataset.FTCNNLSTM was benchmarked against four approaches:CNN,LSTM,CNN-LSTM with random forest,and CNN-LSTM with gradient boosting,all using 460 instances.The FTCNNLSTM model,augmented with TabNet,achieved 96%accuracy,outperforming other methods.This establishes it as a reliable and effective approach for automating bearing fault detection in electric motor-driven systems. 展开更多
关键词 Electric motor-driven systems bearing faults AUTOMATION fine tunned convolutional neural network long short-term memory fault detection
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Optimizing the Clinical Decision Support System (CDSS) by Using Recurrent Neural Network (RNN) Language Models for Real-Time Medical Query Processing
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作者 Israa Ibraheem Al Barazanchi Wahidah Hashim +4 位作者 Reema Thabit Mashary Nawwaf Alrasheedy Abeer Aljohan Jongwoon Park Byoungchol Chang 《Computers, Materials & Continua》 SCIE EI 2024年第12期4787-4832,共46页
This research aims to enhance Clinical Decision Support Systems(CDSS)within Wireless Body Area Networks(WBANs)by leveraging advanced machine learning techniques.Specifically,we target the challenges of accurate diagno... This research aims to enhance Clinical Decision Support Systems(CDSS)within Wireless Body Area Networks(WBANs)by leveraging advanced machine learning techniques.Specifically,we target the challenges of accurate diagnosis in medical imaging and sequential data analysis using Recurrent Neural Networks(RNNs)with Long Short-Term Memory(LSTM)layers and echo state cells.These models are tailored to improve diagnostic precision,particularly for conditions like rotator cuff tears in osteoporosis patients and gastrointestinal diseases.Traditional diagnostic methods and existing CDSS frameworks often fall short in managing complex,sequential medical data,struggling with long-term dependencies and data imbalances,resulting in suboptimal accuracy and delayed decisions.Our goal is to develop Artificial Intelligence(AI)models that address these shortcomings,offering robust,real-time diagnostic support.We propose a hybrid RNN model that integrates SimpleRNN,LSTM layers,and echo state cells to manage long-term dependencies effectively.Additionally,we introduce CG-Net,a novel Convolutional Neural Network(CNN)framework for gastrointestinal disease classification,which outperforms traditional CNN models.We further enhance model performance through data augmentation and transfer learning,improving generalization and robustness against data scarcity and imbalance.Comprehensive validation,including 5-fold cross-validation and metrics such as accuracy,precision,recall,F1-score,and Area Under the Curve(AUC),confirms the models’reliability.Moreover,SHapley Additive exPlanations(SHAP)and Local Interpretable Model-agnostic Explanations(LIME)are employed to improve model interpretability.Our findings show that the proposed models significantly enhance diagnostic accuracy and efficiency,offering substantial advancements in WBANs and CDSS. 展开更多
关键词 Computer science clinical decision support system(CDSS) medical queries healthcare deep learning recurrent neural network(RNN) long short-term memory(LSTM)
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Time-varying parameters estimation with adaptive neural network EKF for missile-dual control system
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作者 YUAN Yuqi ZHOU Di +1 位作者 LI Junlong LOU Chaofei 《Journal of Systems Engineering and Electronics》 SCIE CSCD 2024年第2期451-462,共12页
In this paper, a filtering method is presented to estimate time-varying parameters of a missile dual control system with tail fins and reaction jets as control variables. In this method, the long-short-term memory(LST... In this paper, a filtering method is presented to estimate time-varying parameters of a missile dual control system with tail fins and reaction jets as control variables. In this method, the long-short-term memory(LSTM) neural network is nested into the extended Kalman filter(EKF) to modify the Kalman gain such that the filtering performance is improved in the presence of large model uncertainties. To avoid the unstable network output caused by the abrupt changes of system states,an adaptive correction factor is introduced to correct the network output online. In the process of training the network, a multi-gradient descent learning mode is proposed to better fit the internal state of the system, and a rolling training is used to implement an online prediction logic. Based on the Lyapunov second method, we discuss the stability of the system, the result shows that when the training error of neural network is sufficiently small, the system is asymptotically stable. With its application to the estimation of time-varying parameters of a missile dual control system, the LSTM-EKF shows better filtering performance than the EKF and adaptive EKF(AEKF) when there exist large uncertainties in the system model. 展开更多
关键词 long-short-term memory(LSTM)neural network extended Kalman filter(EKF) rolling training time-varying parameters estimation missile dual control system
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Novel Adaptive Memory Event-Triggered-Based Fuzzy Robust Control for Nonlinear Networked Systems via the Differential Evolution Algorithm
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作者 Wei Qian Yanmin Wu Bo Shen 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第8期1836-1848,共13页
This article mainly investigates the fuzzy optimization robust control issue for nonlinear networked systems characterized by the interval type-2(IT2)fuzzy technique under a differential evolution algorithm.To provide... This article mainly investigates the fuzzy optimization robust control issue for nonlinear networked systems characterized by the interval type-2(IT2)fuzzy technique under a differential evolution algorithm.To provide a more reasonable utilization of the constrained communication channel,a novel adaptive memory event-triggered(AMET)mechanism is developed,where two event-triggered thresholds can be dynamically adjusted in the light of the current system information and the transmitted historical data.Sufficient conditions with less conservative design of the fuzzy imperfect premise matching(IPM)controller are presented by introducing the Wirtinger-based integral inequality,the information of membership functions(MFs)and slack matrices.Subsequently,under the IPM policy,a new MFs intelligent optimization technique that takes advantage of the differential evolution algorithm is first provided for IT2 TakagiSugeno(T-S)fuzzy systems to update the fuzzy controller MFs in real-time and achieve a better system control effect.Finally,simulation results demonstrate that the proposed control scheme can obtain better system performance in the case of using fewer communication resources. 展开更多
关键词 Adaptive memory event-triggered(AMET) differential evolution algorithm fuzzy optimization robust control interval type-2(IT2)fuzzy technique.
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Seasonal Short-Term Load Forecasting for Power Systems Based onModal Decomposition and Feature-FusionMulti-Algorithm Hybrid Neural NetworkModel
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作者 Jiachang Liu Zhengwei Huang +2 位作者 Junfeng Xiang Lu Liu Manlin Hu 《Energy Engineering》 EI 2024年第11期3461-3486,共26页
To enhance the refinement of load decomposition in power systems and fully leverage seasonal change information to further improve prediction performance,this paper proposes a seasonal short-termload combination predi... To enhance the refinement of load decomposition in power systems and fully leverage seasonal change information to further improve prediction performance,this paper proposes a seasonal short-termload combination prediction model based on modal decomposition and a feature-fusion multi-algorithm hybrid neural network model.Specifically,the characteristics of load components are analyzed for different seasons,and the corresponding models are established.First,the improved complete ensemble empirical modal decomposition with adaptive noise(ICEEMDAN)method is employed to decompose the system load for all four seasons,and the new sequence is obtained through reconstruction based on the refined composite multiscale fuzzy entropy of each decomposition component.Second,the correlation between different decomposition components and different features is measured through the max-relevance and min-redundancy method to filter out the subset of features with strong correlation and low redundancy.Finally,different components of the load in different seasons are predicted separately using a bidirectional long-short-term memory network model based on a Bayesian optimization algorithm,with a prediction resolution of 15 min,and the predicted values are accumulated to obtain the final results.According to the experimental findings,the proposed method can successfully balance prediction accuracy and prediction time while offering a higher level of prediction accuracy than the current prediction methods.The results demonstrate that the proposedmethod can effectively address the load power variation induced by seasonal differences in different regions. 展开更多
关键词 Short-term load forecasting seasonal characteristics refined composite multiscale fuzzy entropy(RCMFE) max-relevance and min-redundancy(mRMR) bidirectional long short-term memory(BiLSTM) hyperparameter search
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The Analogy between the Immune System and Human Life
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作者 Gassem Gohal 《Open Journal of Immunology》 2024年第3期47-59,共13页
The immune system operates as a complex organization with distinct roles and functions. Excitingly we recognized the similarities between the cellular dynamics of the immune system and our lives, activities, and behav... The immune system operates as a complex organization with distinct roles and functions. Excitingly we recognized the similarities between the cellular dynamics of the immune system and our lives, activities, and behaviors. Observing the immune system can guide how to respond to various daily situations, including when to react, tolerate, or ignore. Recognizing this analogy between our lives and the immune system should motivate us to adopt a wisdom-based approach when investigating the mechanisms and future discoveries related to this system and to deepen our understanding of this complex system with newfound respect. In this context, the present review examines several integral biological processes of the immune system by drawing parallels between them and human life, activities, and behaviors to learn how we must behave based on the insights offered by this complex organization. The literature search was conducted in international databases such as PubMed/MEDLINE and Google Scholar search engine using English equivalent keywords from 1998 up to April 2023. The search strategy used the following subject heading terms: Immune system, analogy, human life, cellular dynamics, memory, tolerance, and ignorance. In conclusion, the immune system is a complex organization comprising various cells interacting within specific sites and networks, communicating, drawing experiences, and learning how to tolerate certain conditions that make it share certain similarities with human life. 展开更多
关键词 Immune system ANALOGY MEMORY TOLERANCE IGNORANCE
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Low Complexity Digital Pre-Distortion (DPD) for Multi-Band Radio over Fiber Transmission Systems
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作者 Zijian Cheng Xiupu Zhang 《Journal of Computer and Communications》 2024年第11期241-262,共22页
Nonlinear distortion is one of key limiting factors in radio over fiber (RoF) transmission systems. To suppress the nonlinear distortion, digital pre-distortion (DPD) has been investigated considerably. However, for m... Nonlinear distortion is one of key limiting factors in radio over fiber (RoF) transmission systems. To suppress the nonlinear distortion, digital pre-distortion (DPD) has been investigated considerably. However, for multi-band signals, DPD becomes very complex, which limits the applications. To reduce the complexity, many simplified DPDs have been proposed. In this work, a new multidimensional DPD is proposed, in which in-band and out-of-band distortion are separated and the out-of-band distortion is evaluated by sum and differences of all input signals instead of all individual input signals, thus complexity is reduced. An up to 6-band 64-QAM orthogonal frequency division multiplexing (OFDM) signal with each bandwidth of 200 MHz in simulations and a 5-band 20 MHz 64-QAM OFDM signal in experiments are used to validate the pro-posed DPD. The validation is illustrated in the means of power spectrum, AM/AM and AM/PM distortion, and error vector magnitude (EVM) of the received signal constellations. The average EVM improvement by simulation for 3-band, 4-band, 5-band and 6-band signals is 19.97 dB, 18.65 dB, 16.64 dB and 15.44 dB, respectively. The average EVM improvement by experiments for 5-band signals is 8.1 dB. Considering the ten times of bandwidth difference, experiments and simulation agree well. 展开更多
关键词 Multidimensional Digital Predistortion (DPD) memorial Polynomial (MP) Power Amplifier (PA) Radio over Fiber Fronthaul Networks 5G
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Hybrid scientific article recommendation system with COOT optimization
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作者 R.Sivasankari J.Dhilipan 《Data Science and Management》 2024年第2期99-107,共9页
Today, recommendation systems are everywhere, making a variety of activities considerably more manageable. These systems help users by personalizing their suggestions to their interests and needs. They can propose var... Today, recommendation systems are everywhere, making a variety of activities considerably more manageable. These systems help users by personalizing their suggestions to their interests and needs. They can propose various goods, including music, courses, articles, agricultural products, fertilizers, books, movies, and foods. In the case of research articles, recommendation algorithms play an essential role in minimizing the time required for researchers to find relevant articles. Despite multiple challenges, these systems must solve serious issues such as the cold-start problem, article privacy, and changing user interests. This research addresses these issues through the use of two techniques: hybrid recommendation systems and COOT optimization. To generate article recommendations, a hybrid recommendation system integrates features from content-based and graph-based recommendation systems. COOT optimization is used to optimize the results, inspired by the movement of water birds. The proposed method combines a graph-based recommendation system with COOT optimization to increase accuracy and reduce result inaccuracies. When compared to the baseline approaches described, the model provided in this study improves precision by 2.3%, recall by 1.6%, and mean reciprocal rank (MRR) by 5.7%. 展开更多
关键词 Recommendation system COOT optimization Citation network CLASSIFICATION Long short-term memory(LSTM)
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基于Thornthwaite Memorial模型的近54年河南省农业气候生产力时空变化特征分析 被引量:17
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作者 李颜颜 康国华 +2 位作者 张鹏岩 何坚坚 闫宇航 《江苏农业科学》 2018年第7期287-293,共7页
利用河南省1961—2014年近54年的19个气象站逐月逐日气象资料,基于Arc GIS 10.1软件平台,采用气候倾向率、反距离加权插值(简称IDW)、Mann-Kendall检验等方法对降水和气温的时空变化进行分析;同时运用Thornthwaite Memorial模型对农业... 利用河南省1961—2014年近54年的19个气象站逐月逐日气象资料,基于Arc GIS 10.1软件平台,采用气候倾向率、反距离加权插值(简称IDW)、Mann-Kendall检验等方法对降水和气温的时空变化进行分析;同时运用Thornthwaite Memorial模型对农业气候生产力时空特征进行研究,利用SPSS软件分析农业气候生产力对降水量和气温的敏感性。结果表明:(1)河南省近54年的降水量呈波动减少态势,减少幅度为8.92 mm/10年;河南省大部分地区的降水倾向率是负值,主要分布在豫东、豫南和豫北地区;(2)河南省近54年的气温整体呈上升趋势,上升速率为0.157℃/10年,纬度较低的南部地区气温较高,气温较低的地区主要在西部山区,且气温倾向率均为正值;(3)河南省近54年的农业气候生产力总体上呈微弱的上升趋势,农业气候生产力距平变化明显,正距平年份比负距平年份多,呈现由南向北递减的特征,南部农业气候生产力较大,西部的农业气候生产力较小,但大部分地区的农业气候生产力呈下降趋势,豫东和豫南地区农业气候生产力上升速率较快,豫西和豫北地区的则下降;(4)河南省农业气候生产力与降水量相关性显著,但与气温的相关性不显著,气候生产力受降水和气温的双重影响,降水量是影响农业气候生产力的主导因素,气候变暖对气候生产力的提高是有利的。随着降水量的逐渐减小,气温的逐渐增加,对农业气候生产力的影响也在进一步加大,要合理利用水资源,兴修水利来保障农业用水,加强稳固河南省在全国的农业地位。 展开更多
关键词 气候变化 农业气候生产力 时空特征 河南省 Thornthwaite memorial模型
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Landscape Design of Parks Based on Red Tourism——With the Memorial Park of Soviet Republic of China in Ruijin,Jiangxi Province as a Study Case 被引量:1
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作者 范建红 朱雪梅 《Journal of Landscape Research》 2010年第7期34-38,共5页
Red tourism is a derivative product of organized patriotic education and revolutionary education activities.Memorial Park of Soviet Republic of China in Ruijin City,Jiangxi Province,as a representative of red tourism ... Red tourism is a derivative product of organized patriotic education and revolutionary education activities.Memorial Park of Soviet Republic of China in Ruijin City,Jiangxi Province,as a representative of red tourism destination,is designed with red and patriotic education as the principal line to carry forward revolutionary traditions and spirits of Red Army,as well as create "red" garden landscapes with strong patriotism,time spirits and leisure elements. 展开更多
关键词 RED TOURISM PARK design Ruijin City memorial PARK of Soviet REPUBLIC of China
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Neurogenesis dynamics in the olfactory bulb:deciphering circuitry organization, function, and adaptive plasticity
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作者 Moawiah M.Naffaa 《Neural Regeneration Research》 SCIE CAS 2025年第6期1565-1581,共17页
Adult neurogenesis persists after birth in the subventricular zone, with new neurons migrating to the granule cell layer and glomerular layers of the olfactory bulb, where they integrate into existing circuitry as inh... Adult neurogenesis persists after birth in the subventricular zone, with new neurons migrating to the granule cell layer and glomerular layers of the olfactory bulb, where they integrate into existing circuitry as inhibitory interneurons. The generation of these new neurons in the olfactory bulb supports both structural and functional plasticity, aiding in circuit remodeling triggered by memory and learning processes. However, the presence of these neurons, coupled with the cellular diversity within the olfactory bulb, presents an ongoing challenge in understanding its network organization and function. Moreover,the continuous integration of new neurons in the olfactory bulb plays a pivotal role in regulating olfactory information processing. This adaptive process responds to changes in epithelial composition and contributes to the formation of olfactory memories by modulating cellular connectivity within the olfactory bulb and interacting intricately with higher-order brain regions. The role of adult neurogenesis in olfactory bulb functions remains a topic of debate. Nevertheless, the functionality of the olfactory bulb is intricately linked to the organization of granule cells around mitral and tufted cells. This organizational pattern significantly impacts output, network behavior, and synaptic plasticity, which are crucial for olfactory perception and memory. Additionally, this organization is further shaped by axon terminals originating from cortical and subcortical regions. Despite the crucial role of olfactory bulb in brain functions and behaviors related to olfaction, these complex and highly interconnected processes have not been comprehensively studied as a whole. Therefore, this manuscript aims to discuss our current understanding and explore how neural plasticity and olfactory neurogenesis contribute to enhancing the adaptability of the olfactory system. These mechanisms are thought to support olfactory learning and memory, potentially through increased complexity and restructuring of neural network structures, as well as the addition of new granule granule cells that aid in olfactory adaptation. Additionally, the manuscript underscores the importance of employing precise methodologies to elucidate the specific roles of adult neurogenesis amidst conflicting data and varying experimental paradigms. Understanding these processes is essential for gaining insights into the complexities of olfactory function and behavior. 展开更多
关键词 network adaptability NEUROGENESIS neuronal communication olfactory bulb olfactory learning olfactory memory synaptic plasticity
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The complex roles of m^(6)A modifications in neural stem cell proliferation, differentiation, and self-renewal and implications for memory and neurodegenerative diseases
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作者 Yanxi Li Jing Xue +8 位作者 Yuejia Ma Ke Ye Xue Zhao Fangliang Ge Feifei Zheng Lulu Liu Xu Gao Dayong Wang Qing Xia 《Neural Regeneration Research》 SCIE CAS 2025年第6期1582-1598,共17页
N6-methyladenosine(m^(6)A), the most prevalent and conserved RNA modification in eukaryotic cells, profoundly influences virtually all aspects of mRNA metabolism. mRNA plays crucial roles in neural stem cell genesis a... N6-methyladenosine(m^(6)A), the most prevalent and conserved RNA modification in eukaryotic cells, profoundly influences virtually all aspects of mRNA metabolism. mRNA plays crucial roles in neural stem cell genesis and neural regeneration, where it is highly concentrated and actively involved in these processes. Changes in m^(6)A modification levels and the expression levels of related enzymatic proteins can lead to neurological dysfunction and contribute to the development of neurological diseases. Furthermore, the proliferation and differentiation of neural stem cells, as well as nerve regeneration, are intimately linked to memory function and neurodegenerative diseases. This paper presents a comprehensive review of the roles of m^(6)A in neural stem cell proliferation, differentiation, and self-renewal, as well as its implications in memory and neurodegenerative diseases. m^(6)A has demonstrated divergent effects on the proliferation and differentiation of neural stem cells. These observed contradictions may arise from the time-specific nature of m^(6)A and its differential impact on neural stem cells across various stages of development. Similarly, the diverse effects of m^(6)A on distinct types of memory could be attributed to the involvement of specific brain regions in memory formation and recall. Inconsistencies in m^(6)A levels across different models of neurodegenerative disease, particularly Alzheimer's disease and Parkinson's disease, suggest that these disparities are linked to variations in the affected brain regions. Notably, the opposing changes in m^(6)A levels observed in Parkinson's disease models exposed to manganese compared to normal Parkinson's disease models further underscore the complexity of m^(6)A's role in neurodegenerative processes. The roles of m^(6)A in neural stem cell proliferation, differentiation, and self-renewal, and its implications in memory and neurodegenerative diseases, appear contradictory. These inconsistencies may be attributed to the timespecific nature of m^(6)A and its varying effects on distinct brain regions and in different environments. 展开更多
关键词 Alzheimer's disease cell self-renewal central nervous system MEMORY MICROGLIA nerve regeneration neurodegenerative diseases NEUROGENESIS RNA methylation
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A Novel Multivalued Associative Memory System
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作者 李克 裴文江 +1 位作者 杨绿溪 何振亚 《Journal of Southeast University(English Edition)》 EI CAS 1998年第2期7-12,共6页
Globally coupled map (GCM) model can evolve through chaotic searching into several stable periodic orbits under properly controlled parameters. This can be exploited in information processing such as associative memor... Globally coupled map (GCM) model can evolve through chaotic searching into several stable periodic orbits under properly controlled parameters. This can be exploited in information processing such as associative memory and optimization. In this paper, we propose a novel covariance learning rule for multivalue patterns and apply it in memorization of gray scale images based on modified GCM model (S GCM). Analysis of retrieval results are given finally. 展开更多
关键词 globally coupled map chaotic neural networks associative memory PATTERN
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Exercise preconditioning alleviates ischemia-induced memory deficits by increasing circulating adiponectin
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作者 Meifeng Zheng Borui Zhang +3 位作者 Sonata S Y Yau Kwok-Fai So Li Zhang Haining Ou 《Neural Regeneration Research》 SCIE CAS 2025年第5期1445-1454,共10页
Cerebral ischemia is a major health risk that requires preventive approaches in addition to drug therapy.Physical exercise enhances neurogenesis and synaptogenesis,and has been widely used for functional rehabilitatio... Cerebral ischemia is a major health risk that requires preventive approaches in addition to drug therapy.Physical exercise enhances neurogenesis and synaptogenesis,and has been widely used for functional rehabilitation after stroke.In this study,we determined whether exercise training before disease onset can alleviate the severity of cerebral ischemia.We also examined the role of exercise-induced circulating factors in these effects.Adult mice were subjected to 14 days of treadmill exercise training before surgery for middle cerebral artery occlusion.We found that this exercise pre-conditioning strategy effectively attenuated brain infarct area,inhibited gliogenesis,protected synaptic proteins,and improved novel object and spatial memory function.Further analysis showed that circulating adiponectin plays a critical role in these preventive effects of exercise.Agonist activation of adiponectin receptors by Adipo Ron mimicked the effects of exercise,while inhibiting receptor activation abolished the exercise effects.In summary,our results suggest a crucial role of circulating adiponectin in the effects of exercise pre-conditioning in protecting against cerebral ischemia and supporting the health benefits of exercise. 展开更多
关键词 ADIPONECTIN cerebral ischemia exercise pre-conditioning HIPPOCAMPUS memory function middle cerebral artery occlusion prefrontal cortex synaptic proteins treadmill exercise
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Ultra‑Transparent and Multifunctional IZVO Mesh Electrodes for Next‑Generation Flexible Optoelectronics
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作者 Kiran A.Nirmal Tukaram D.Dongale +3 位作者 Atul C.Khot Chenjie Yao Nahyun Kim Tae Geun Kim 《Nano-Micro Letters》 SCIE EI CAS 2025年第1期293-309,共17页
Mechanically durable transparent electrodes are essential for achieving long-term stability in flexible optoelectronic devices.Furthermore,they are crucial for applications in the fields of energy,display,healthcare,a... Mechanically durable transparent electrodes are essential for achieving long-term stability in flexible optoelectronic devices.Furthermore,they are crucial for applications in the fields of energy,display,healthcare,and soft robotics.Conducting meshes represent a promising alternative to traditional,brittle,metal oxide conductors due to their high electrical conductivity,optical transparency,and enhanced mechanical flexibility.In this paper,we present a simple method for fabricating an ultra-transparent conducting metal oxide mesh electrode using selfcracking-assisted templates.Using this method,we produced an electrode with ultra-transparency(97.39%),high conductance(Rs=21.24Ωsq^(−1)),elevated work function(5.16 eV),and good mechanical stability.We also evaluated the effectiveness of the fabricated electrodes by integrating them into organic photovoltaics,organic light-emitting diodes,and flexible transparent memristor devices for neuromorphic computing,resulting in exceptional device performance.In addition,the unique porous structure of the vanadium-doped indium zinc oxide mesh electrodes provided excellent flexibility,rendering them a promising option for application in flexible optoelectronics. 展开更多
关键词 Self-cracking template Vanadium-doped indium zinc oxide mesh Organic solar cells Organic light-emitting diodes Flexible transparent memory
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Recombinant chitinase-3-like protein 1 alleviates learning and memory impairments via M2 microglia polarization in postoperative cognitive dysfunction mice
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作者 Yujia Liu Xue Han +6 位作者 Yan Su Yiming Zhou Minhui Xu Jiyan Xu Zhengliang Ma Xiaoping Gu Tianjiao Xia 《Neural Regeneration Research》 SCIE CAS 2025年第9期2727-2736,共10页
Postoperative cognitive dysfunction is a seve re complication of the central nervous system that occurs after anesthesia and surgery,and has received attention for its high incidence and effect on the quality of life ... Postoperative cognitive dysfunction is a seve re complication of the central nervous system that occurs after anesthesia and surgery,and has received attention for its high incidence and effect on the quality of life of patients.To date,there are no viable treatment options for postoperative cognitive dysfunction.The identification of postoperative cognitive dysfunction hub genes could provide new research directions and therapeutic targets for future research.To identify the signaling mechanisms contributing to postoperative cognitive dysfunction,we first conducted Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses of the Gene Expression Omnibus GSE95426 dataset,which consists of mRNAs and long non-coding RNAs differentially expressed in mouse hippocampus3 days after tibial fracture.The dataset was enriched in genes associated with the biological process"regulation of immune cells,"of which Chill was identified as a hub gene.Therefore,we investigated the contribution of chitinase-3-like protein 1 protein expression changes to postoperative cognitive dysfunction in the mouse model of tibial fractu re surgery.Mice were intraperitoneally injected with vehicle or recombinant chitinase-3-like protein 124 hours post-surgery,and the injection groups were compared with untreated control mice for learning and memory capacities using the Y-maze and fear conditioning tests.In addition,protein expression levels of proinflammatory factors(interleukin-1βand inducible nitric oxide synthase),M2-type macrophage markers(CD206 and arginase-1),and cognition-related proteins(brain-derived neurotropic factor and phosphorylated NMDA receptor subunit NR2B)were measured in hippocampus by western blotting.Treatment with recombinant chitinase-3-like protein 1 prevented surgery-induced cognitive impairment,downregulated interleukin-1βand nducible nitric oxide synthase expression,and upregulated CD206,arginase-1,pNR2B,and brain-derived neurotropic factor expression compared with vehicle treatment.Intraperitoneal administration of the specific ERK inhibitor PD98059 diminished the effects of recombinant chitinase-3-like protein 1.Collectively,our findings suggest that recombinant chitinase-3-like protein 1 ameliorates surgery-induced cognitive decline by attenuating neuroinflammation via M2 microglial polarization in the hippocampus.Therefore,recombinant chitinase-3-like protein1 may have therapeutic potential fo r postoperative cognitive dysfunction. 展开更多
关键词 Chil1 hippocampus learning and memory M2 microglia NEUROINFLAMMATION postoperative cognitive dysfunction(POCD) recombinant CHI3L1
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Regulator of G protein signaling 6 mediates exercise-induced recovery of hippocampal neurogenesis,learning,and memory in a mouse model of Alzheimer’s disease
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作者 Mackenzie M.Spicer Jianqi Yang +5 位作者 Daniel Fu Alison N.DeVore Marisol Lauffer Nilufer S.Atasoy Deniz Atasoy Rory A.Fisher 《Neural Regeneration Research》 SCIE CAS 2025年第10期2969-2981,共13页
Hippocampal neuronal loss causes cognitive dysfunction in Alzheimer’s disease.Adult hippocampal neurogenesis is reduced in patients with Alzheimer’s disease.Exercise stimulates adult hippocampal neurogenesis in rode... Hippocampal neuronal loss causes cognitive dysfunction in Alzheimer’s disease.Adult hippocampal neurogenesis is reduced in patients with Alzheimer’s disease.Exercise stimulates adult hippocampal neurogenesis in rodents and improves memory and slows cognitive decline in patients with Alzheimer’s disease.However,the molecular pathways for exercise-induced adult hippocampal neurogenesis and improved cognition in Alzheimer’s disease are poorly understood.Recently,regulator of G protein signaling 6(RGS6)was identified as the mediator of voluntary running-induced adult hippocampal neurogenesis in mice.Here,we generated novel RGS6fl/fl;APP_(SWE) mice and used retroviral approaches to examine the impact of RGS6 deletion from dentate gyrus neuronal progenitor cells on voluntary running-induced adult hippocampal neurogenesis and cognition in an amyloid-based Alzheimer’s disease mouse model.We found that voluntary running in APP_(SWE) mice restored their hippocampal cognitive impairments to that of control mice.This cognitive rescue was abolished by RGS6 deletion in dentate gyrus neuronal progenitor cells,which also abolished running-mediated increases in adult hippocampal neurogenesis.Adult hippocampal neurogenesis was reduced in sedentary APP_(SWE) mice versus control mice,with basal adult hippocampal neurogenesis reduced by RGS6 deletion in dentate gyrus neural precursor cells.RGS6 was expressed in neurons within the dentate gyrus of patients with Alzheimer’s disease with significant loss of these RGS6-expressing neurons.Thus,RGS6 mediated voluntary running-induced rescue of impaired cognition and adult hippocampal neurogenesis in APP_(SWE) mice,identifying RGS6 in dentate gyrus neural precursor cells as a possible therapeutic target in Alzheimer’s disease. 展开更多
关键词 adult hippocampal neurogenesis Alzheimer’s disease dentate gyrus EXERCISE learning/memory neural precursor cells regulator of G protein signaling 6(RGS6)
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Aesthetic comparison between Chinese memorial poetry and western elegy
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作者 张丽娟 王旻 《Sino-US English Teaching》 2007年第8期76-81,共6页
Owing to the cultural, philosophical and religious differences, Chinese memorial poetry and western elegy show different attitudes towards death and have different ways to express it. Therefore, they have different ae... Owing to the cultural, philosophical and religious differences, Chinese memorial poetry and western elegy show different attitudes towards death and have different ways to express it. Therefore, they have different aesthetic preference to death. This paper focuses on the basic characteristics of Chinese memorial poetry and western elegy. It analyzes the causes of these differences from the aspect of the content and style, ways of expression and cultural psychology. 展开更多
关键词 memorial poetry ELEGY DIFFERENCE cultural root
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Does exercise have a protective effect on cognitive function under hypoxia? A systematic review with meta-analysis 被引量:5
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作者 Myungjin Jung Liye Zou +8 位作者 Jane Jie Yu Seungho Ryu Zhaowei Kong Lin Yang Minsoo Kang Jingyuan Lin Hong Li Lee Smith Paul D.Loprinzi 《Journal of Sport and Health Science》 SCIE 2020年第6期562-577,共16页
Objective:This study aimed to examine(1)the independent effects of hypoxia on cognitive function and(2)the effects of exercise on cognition while under hypoxia.Methods:Design:Systematic review with meta-analysis.Data ... Objective:This study aimed to examine(1)the independent effects of hypoxia on cognitive function and(2)the effects of exercise on cognition while under hypoxia.Methods:Design:Systematic review with meta-analysis.Data sources:PubMed,Scopus,Web of Science,PsychInfo,and SPORTDiscus were searched.Eligibility criteria for selecting studies:randomized controlled trials and nonrandomized controlled studies that investigated the effects of chronic or acute exercise on cognition under hypoxia were considered(Aim 2),as were studies investigating the effects of hypoxia on cognition(Aim 1).Results:In total,18 studies met our inclusionary criteria for the systematic review,and 12 studies were meta-analyzed.Exposure to hypoxia impaired attentional ability(standardized mean difference(SMD)=-0.4),executive function(SMD=-0.18),and memory function(SMD=-0.26),but not information processing(SMD=0.27).Aggregated results indicated that performing exercise under a hypoxia setting had a significant effect on cognitive improvement(SMD=0.3,95%confidence interval:0.14-0.45,I^2=54%,p<0.001).Various characteristics(e.g.,age,cognitive task type,exercise type,exercise intensity,training type,and hypoxia level)moderated the effects of hypoxia and exercise on cognitive function.Conclusion:Exercise during exposure to hypoxia improves cognitive function.This association appears to be moderated by individual and exercise/hypoxia-related characteristics. 展开更多
关键词 COGNITION Executive function EXERCISE HYPOXIA Memory
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Prediction of Precipitation during Summer Monsoon with Self-memorial Model 被引量:5
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作者 封国林 曹鸿兴 +2 位作者 高新全 董文杰 丑纪范 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2001年第5期701-709,共9页
In view of the fact that the atmospheric motion is an irreversible process, a memory function which can recall the observation data in the past is introduced, moreover, a special concept of self-memorization of the at... In view of the fact that the atmospheric motion is an irreversible process, a memory function which can recall the observation data in the past is introduced, moreover, a special concept of self-memorization of the atmospheric motion is proposed, and a so-called self-memorization equation of the atmospheric motion has been derived. Based on the self-memorization principle, a numerical model for decadal forecast is established by means of the thermodynamic equation and the precipitation equation. The verification scores of the hindcasts of the model in the period from 1 to 12 years are much higher than that of monthly weather forecasts at present. 展开更多
关键词 numerical model climatic prediction memory
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