This thesis has further studied the low resistance of meridian points with a new in-strument called Model TZ-03 of resistance detector for Acupoints. Through experiments and clinicalobservation, the author found that ...This thesis has further studied the low resistance of meridian points with a new in-strument called Model TZ-03 of resistance detector for Acupoints. Through experiments and clinicalobservation, the author found that the changes of skin resistances of points are closely related to thechanges of human physiology and pathology. The experiments also show that the factors which influ-ence the results are complicated and changeable in many ways. Therefore, the absolute values of theresistances of points are not precise and stahle f and the ratio of the resistance of bilateral point of thesame name is more re1iable. In healthy people, the resistances of the sarne points on two sides of thebody are similar, and there is much difference of these resistances among people with diseases.展开更多
Focusing on the effect specificity of meridian points along the running course of meridian,by taking the treatment of post-stroke depression(PSD)with the acupoints of the governor vessel as an example,the correlation ...Focusing on the effect specificity of meridian points along the running course of meridian,by taking the treatment of post-stroke depression(PSD)with the acupoints of the governor vessel as an example,the correlation between meridian points and disease was explored.The specific regulatory effect of governor vessel,Baihui(百会GV20)and Shenting(神庭GV24)in physiology and pathology in PSD and the material basis of the specificity effect were analyzed.Finally,the specific relationship between the acupoints of the governor vessel and PSD was explained.展开更多
目的探讨子午流注择时耳穴压豆治疗对2型糖尿病(T2DM)患者血糖控制、上消症状及失眠状况的影响。方法选取2020年1月至2022年12月河南省中西医结合医院内分泌科收治的138例T2DM患者作为研究对象,依据电脑数表随机抽取法分为西医组(常规...目的探讨子午流注择时耳穴压豆治疗对2型糖尿病(T2DM)患者血糖控制、上消症状及失眠状况的影响。方法选取2020年1月至2022年12月河南省中西医结合医院内分泌科收治的138例T2DM患者作为研究对象,依据电脑数表随机抽取法分为西医组(常规西医干预)46例、中医1组(耳穴压豆干预)46例和中医2组(子午流注择时耳穴压豆干预)46例,连续干预4周。比较三组患者的治疗总有效率、治疗前后的血糖水平[空腹血糖(FBG)、餐后2 h血糖(2 h PBG)、糖化血红蛋白(Hb1Ac)]、上消症状、睡眠质量[匹兹堡睡眠治疗指数(PSQI)]、Toll样受体4(TLR4)/细胞核因子κB(NF-κB)炎症信号通路因子[外周血TLR4、NF-κB、血清肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)]水平及不良反应发生情况。结果中医2组、中医1组患者的治疗总有效率分别为93.48%、84.78%,明显高于西医组的71.74%,差异均有统计学意义(P<0.05);干预4周后,中医2组患者的FBG、2 h PBG、Hb1Ac水平分别为(6.36±0.83)mmol/L、(8.18±1.05)mmol/L、(6.13±0.59)%,明显低于中医1组的(7.05±1.02)mmol/L、(9.37±1.16)mmol/L、(6.91±0.83)%及西医组的(7.81±1.10)mmol/L、(10.80±1.44)mmol/L、(7.88±0.75)%,差异均有统计学意义(P<0.05);干预4周后,中医2组患者的口干、多饮症状积分、PSQI各维度评分及总分明显低于中医1组、西医组,中医1组明显低于西医组,差异均有统计学意义(P<0.05);干预4周后,中医2组患者的外周血TLR4、NF-κB蛋白及血清TNF-α、IL-6水平分别为1.26±0.24、1.31±0.25、(26.76±4.38)pg/mL、(17.72±3.34)pg/mL,明显低于中医1组的1.59±0.31、1.53±0.29、(31.54±4.71)pg/mL、(20.53±4.11)pg/mL及西医组的2.02±0.35、2.06±0.37、(34.07±5.23)pg/mL、(23.18±3.62)pg/mL,差异均有统计学意义(P<0.05);三组患者治疗期间的总不良反应发生率比较差异无统计学意义(P>0.05)。结论子午流注择时耳穴压豆治疗T2DM具有一定的治疗效果,其可控制血糖水平,改善上消症状,提高睡眠质量,且具有一定安全性,其治疗机制可能与调节TLR4/NF-κB炎症信号通路有关。展开更多
目的基于磁共振成像观察穴位埋线对单纯性肥胖患者局部经穴(天枢、脾俞、丰隆)刺激效应的时效特点。方法应用T2-mapping技术采集15例单纯性肥胖患者左侧天枢、脾俞、丰隆穴埋线前后不同时间段T2WI压脂及T2-mapping 8回波序列图像,传入...目的基于磁共振成像观察穴位埋线对单纯性肥胖患者局部经穴(天枢、脾俞、丰隆)刺激效应的时效特点。方法应用T2-mapping技术采集15例单纯性肥胖患者左侧天枢、脾俞、丰隆穴埋线前后不同时间段T2WI压脂及T2-mapping 8回波序列图像,传入后处理工作站生成伪彩图,获取信号最强的连续3个层面感兴趣区(region of interest,ROI)的T2值均数,分析天枢、脾俞、丰隆穴局部T2WI压脂序列图像的信号影强弱和T2值随时间变化的特点。结果天枢穴埋线后1、4 d ROI的T2值均较埋线前显著升高(P<0.05),均可见不同高信号影;埋线后1、2、3、4、5周ROI的T2值较埋线后4d显著下降(P<0.05),各时间段信号影接近埋线前。脾俞穴埋线后1、4 d及埋线后1周ROI的T2值均较埋线前显著升高(P<0.05),均可见不同高信号影;埋线后2、3、4、5周ROI的T2值较埋线后1周显著下降(P<0.05),各时间段信号影接近埋线前。丰隆穴埋线后1、4 d及埋线后1、2周ROI的T2值均较埋线前显著升高(P<0.05),均可见不同高信号影;埋线后3、4、5周ROI的T2值较埋线后2周显著下降(P<0.05),各时间段信号影接近埋线前。结论单纯性肥胖患者埋线后穴位刺激效应具有不同的时效特点,天枢约1周,脾俞约2周,丰隆约3周。故单纯性肥胖患者埋线减肥时,建议可参照腹部1周、背部2周、下肢3周的间隔周期治疗。展开更多
文摘This thesis has further studied the low resistance of meridian points with a new in-strument called Model TZ-03 of resistance detector for Acupoints. Through experiments and clinicalobservation, the author found that the changes of skin resistances of points are closely related to thechanges of human physiology and pathology. The experiments also show that the factors which influ-ence the results are complicated and changeable in many ways. Therefore, the absolute values of theresistances of points are not precise and stahle f and the ratio of the resistance of bilateral point of thesame name is more re1iable. In healthy people, the resistances of the sarne points on two sides of thebody are similar, and there is much difference of these resistances among people with diseases.
基金Supported by National Natural Science Foundation of China:81804161,Natural Science Foundation of Jiangsu Province:BK20171070
文摘Focusing on the effect specificity of meridian points along the running course of meridian,by taking the treatment of post-stroke depression(PSD)with the acupoints of the governor vessel as an example,the correlation between meridian points and disease was explored.The specific regulatory effect of governor vessel,Baihui(百会GV20)and Shenting(神庭GV24)in physiology and pathology in PSD and the material basis of the specificity effect were analyzed.Finally,the specific relationship between the acupoints of the governor vessel and PSD was explained.
文摘目的探讨子午流注择时耳穴压豆治疗对2型糖尿病(T2DM)患者血糖控制、上消症状及失眠状况的影响。方法选取2020年1月至2022年12月河南省中西医结合医院内分泌科收治的138例T2DM患者作为研究对象,依据电脑数表随机抽取法分为西医组(常规西医干预)46例、中医1组(耳穴压豆干预)46例和中医2组(子午流注择时耳穴压豆干预)46例,连续干预4周。比较三组患者的治疗总有效率、治疗前后的血糖水平[空腹血糖(FBG)、餐后2 h血糖(2 h PBG)、糖化血红蛋白(Hb1Ac)]、上消症状、睡眠质量[匹兹堡睡眠治疗指数(PSQI)]、Toll样受体4(TLR4)/细胞核因子κB(NF-κB)炎症信号通路因子[外周血TLR4、NF-κB、血清肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)]水平及不良反应发生情况。结果中医2组、中医1组患者的治疗总有效率分别为93.48%、84.78%,明显高于西医组的71.74%,差异均有统计学意义(P<0.05);干预4周后,中医2组患者的FBG、2 h PBG、Hb1Ac水平分别为(6.36±0.83)mmol/L、(8.18±1.05)mmol/L、(6.13±0.59)%,明显低于中医1组的(7.05±1.02)mmol/L、(9.37±1.16)mmol/L、(6.91±0.83)%及西医组的(7.81±1.10)mmol/L、(10.80±1.44)mmol/L、(7.88±0.75)%,差异均有统计学意义(P<0.05);干预4周后,中医2组患者的口干、多饮症状积分、PSQI各维度评分及总分明显低于中医1组、西医组,中医1组明显低于西医组,差异均有统计学意义(P<0.05);干预4周后,中医2组患者的外周血TLR4、NF-κB蛋白及血清TNF-α、IL-6水平分别为1.26±0.24、1.31±0.25、(26.76±4.38)pg/mL、(17.72±3.34)pg/mL,明显低于中医1组的1.59±0.31、1.53±0.29、(31.54±4.71)pg/mL、(20.53±4.11)pg/mL及西医组的2.02±0.35、2.06±0.37、(34.07±5.23)pg/mL、(23.18±3.62)pg/mL,差异均有统计学意义(P<0.05);三组患者治疗期间的总不良反应发生率比较差异无统计学意义(P>0.05)。结论子午流注择时耳穴压豆治疗T2DM具有一定的治疗效果,其可控制血糖水平,改善上消症状,提高睡眠质量,且具有一定安全性,其治疗机制可能与调节TLR4/NF-κB炎症信号通路有关。
文摘目的基于磁共振成像观察穴位埋线对单纯性肥胖患者局部经穴(天枢、脾俞、丰隆)刺激效应的时效特点。方法应用T2-mapping技术采集15例单纯性肥胖患者左侧天枢、脾俞、丰隆穴埋线前后不同时间段T2WI压脂及T2-mapping 8回波序列图像,传入后处理工作站生成伪彩图,获取信号最强的连续3个层面感兴趣区(region of interest,ROI)的T2值均数,分析天枢、脾俞、丰隆穴局部T2WI压脂序列图像的信号影强弱和T2值随时间变化的特点。结果天枢穴埋线后1、4 d ROI的T2值均较埋线前显著升高(P<0.05),均可见不同高信号影;埋线后1、2、3、4、5周ROI的T2值较埋线后4d显著下降(P<0.05),各时间段信号影接近埋线前。脾俞穴埋线后1、4 d及埋线后1周ROI的T2值均较埋线前显著升高(P<0.05),均可见不同高信号影;埋线后2、3、4、5周ROI的T2值较埋线后1周显著下降(P<0.05),各时间段信号影接近埋线前。丰隆穴埋线后1、4 d及埋线后1、2周ROI的T2值均较埋线前显著升高(P<0.05),均可见不同高信号影;埋线后3、4、5周ROI的T2值较埋线后2周显著下降(P<0.05),各时间段信号影接近埋线前。结论单纯性肥胖患者埋线后穴位刺激效应具有不同的时效特点,天枢约1周,脾俞约2周,丰隆约3周。故单纯性肥胖患者埋线减肥时,建议可参照腹部1周、背部2周、下肢3周的间隔周期治疗。
