A resistor-capacitor(RC)circuit model is proposed to study the effect of nanosecond pulsed electricfield on cells according to the structure and electrical parameters of cells.After a nanosecond step fieldhas been app...A resistor-capacitor(RC)circuit model is proposed to study the effect of nanosecond pulsed electricfield on cells according to the structure and electrical parameters of cells.After a nanosecond step fieldhas been applied,the variation of voltages across cytomembrane and mitochondria membrane both in nor-mal and in malignant cells are studied with this model.The time for selectively targeting the mitochondriamembrane and malignant cell can be evaluated much easily with curves that show the variation of voltageacross each membrane with time.Ramp field is the typical field applied in electrobiology.The voltagesacross each membrane induced by ramp field are analyzed with this model.To selectively target the mito-chondria membrane,proper range of ramp slope is needed.It is relatively difficult to decide the range ofa slope to selectively affect the malignant cell.Under some conditions,such a range even does not exist.展开更多
This work presents an implementation of an innovative single phase multilevel inverter using capacitors with reduced switches. The proposed Capacitor pattern H-bridge Multilevel Inverter (CPHMLI) topology consists of ...This work presents an implementation of an innovative single phase multilevel inverter using capacitors with reduced switches. The proposed Capacitor pattern H-bridge Multilevel Inverter (CPHMLI) topology consists of a proper number of Capacitor connected with switches and power sources. The advanced switching control supplied by Pulse Width Modulation (PDPWM) to attain mixed staircase switching state. The charging and discharging mode are achieved by calculating the voltage error at the load. Furthermore, to accomplish the higher voltage levels at the output with less number of semiconductors switches and simple commutation designed using CPHMLI topology. To prove the performance and effectiveness of the proposed approach, a set of experiments performed under various load conditions using MATLAB tool.展开更多
This paper presents a unique voltage-raising topology for a single-phase seven-level inverter with triple output voltage gain using single input source and two switched capacitors.The output voltage has been boosted u...This paper presents a unique voltage-raising topology for a single-phase seven-level inverter with triple output voltage gain using single input source and two switched capacitors.The output voltage has been boosted up to three times the value of input voltage by configuring the switched capacitors in series and parallel combinations which eliminates the use of additional step-up converters and transformers.The selective harmonic elimination(SHE)approach is used to remove the lower-order harmonics.The optimal switching angles for SHE is determined using the genetic algorithm.These switching angles are com-bined with a level-shifted pulse width modulation(PWM)technique for pulse generation,resulting in reduced total harmonic distortion(THD).A detailed com-parison has been made against other relevant seven-level inverter topologies in terms of the number of switches,drivers,diodes,capacitors,and boosting facil-ities to emphasize the benefits of the proposed model.The proposed topology is simulated using MATLAB/SIMULINK and an experimental prototype has been developed to validate the results.The Digital Signal Processing(DSP)TMS320F2812 board is used to generate the switching pulses for the proposed technique and the experimental results concur with the simulated model outputs.展开更多
基金Supported by National Natural Science Foundation of China (50477007)
文摘A resistor-capacitor(RC)circuit model is proposed to study the effect of nanosecond pulsed electricfield on cells according to the structure and electrical parameters of cells.After a nanosecond step fieldhas been applied,the variation of voltages across cytomembrane and mitochondria membrane both in nor-mal and in malignant cells are studied with this model.The time for selectively targeting the mitochondriamembrane and malignant cell can be evaluated much easily with curves that show the variation of voltageacross each membrane with time.Ramp field is the typical field applied in electrobiology.The voltagesacross each membrane induced by ramp field are analyzed with this model.To selectively target the mito-chondria membrane,proper range of ramp slope is needed.It is relatively difficult to decide the range ofa slope to selectively affect the malignant cell.Under some conditions,such a range even does not exist.
文摘This work presents an implementation of an innovative single phase multilevel inverter using capacitors with reduced switches. The proposed Capacitor pattern H-bridge Multilevel Inverter (CPHMLI) topology consists of a proper number of Capacitor connected with switches and power sources. The advanced switching control supplied by Pulse Width Modulation (PDPWM) to attain mixed staircase switching state. The charging and discharging mode are achieved by calculating the voltage error at the load. Furthermore, to accomplish the higher voltage levels at the output with less number of semiconductors switches and simple commutation designed using CPHMLI topology. To prove the performance and effectiveness of the proposed approach, a set of experiments performed under various load conditions using MATLAB tool.
文摘This paper presents a unique voltage-raising topology for a single-phase seven-level inverter with triple output voltage gain using single input source and two switched capacitors.The output voltage has been boosted up to three times the value of input voltage by configuring the switched capacitors in series and parallel combinations which eliminates the use of additional step-up converters and transformers.The selective harmonic elimination(SHE)approach is used to remove the lower-order harmonics.The optimal switching angles for SHE is determined using the genetic algorithm.These switching angles are com-bined with a level-shifted pulse width modulation(PWM)technique for pulse generation,resulting in reduced total harmonic distortion(THD).A detailed com-parison has been made against other relevant seven-level inverter topologies in terms of the number of switches,drivers,diodes,capacitors,and boosting facil-ities to emphasize the benefits of the proposed model.The proposed topology is simulated using MATLAB/SIMULINK and an experimental prototype has been developed to validate the results.The Digital Signal Processing(DSP)TMS320F2812 board is used to generate the switching pulses for the proposed technique and the experimental results concur with the simulated model outputs.
