The present study aimed to evaluate the effects of manganese methionine hydroxyl analog chelated(Mn-MHAC)as a manganese(Mn)source on growth performance and trace element deposition in broilers.A total of 432 Arbor Acr...The present study aimed to evaluate the effects of manganese methionine hydroxyl analog chelated(Mn-MHAC)as a manganese(Mn)source on growth performance and trace element deposition in broilers.A total of 432 Arbor Acres commercial female broilers were fed a basal corn-soybean diet containing Mn at 25.64 mg/kg diet for 10 d.They were then randomly assigned to 6 groups,including a control group(the basal diet),a Mn sulfate group(the basal diet supplemented with Mn at 100 mg/kg diet),and 4 Mn-MHAC groups(the basal diet supplemented with Mn-MHAC at 25,50,75 and 100 mg Mn/kg diet,respectively).The results showed that compared with the control group,groups supplemented with Mn-MHAC had a positive effect on BW(quadratic,P=0.017)and ADG(quadratic,P=0.017).Moreover,the Mn-MHAC(50 mg Mn/kg diet)group had significantly greater BW and ADG(P<0.05)compared with the other Mn-MHAC groups.Trace element deposition results also showed that tibial Mn increased(linear or quadratic,P-0.002 and 0.009,respectively)in groups fed diets with increased levels of Mn-MHAC.In contrast,Fe deposition decreased both in the heart(linear,P-0.020)and tibia(P<0.05).In addition,the Mn-MHAC supplement noticeably lowered serum Mn-SOD activity(linear or quadratic,P-0.048 and 0.019,respectively).The relative mRNA levels of divalent metal transporter 1(DMT1)(P=0.024),ferro-portin 1(FPN1)(P=0.049),and Cu transporter-1(CTR1)(P<0.001)in the duodenum,as well as CTR1 in the jejunum and ileum(P=0.040 and 0.011,respectively)were higher in the Mn-supplemented group than in the control group.Furthermore,the relative mRNA level of DMT1 in the jejunum and ileum of broilers in the Mn-MHAC group(50 mg Mn/kg diet)did not differ from those in the control group,but was lower than those in the Mn sulfate group(P<0.05).In conclusion,Mn-MHAC dietary supplementation improved the growth performance and trace element deposition in broilers.From this study,we recommend the opti-mum Mn-MHAC level to meet the Mn requirement of broilers is 50 to 75 mg Mn/kg diet.展开更多
基金National key research and development program of China(2016YFD0200900,2016YFD0501200)the Chinese Academy of Science STS Project(KFJ-STS-QYZD-095)Agricultural innovation project of Hunan Province(2019TD01).
文摘The present study aimed to evaluate the effects of manganese methionine hydroxyl analog chelated(Mn-MHAC)as a manganese(Mn)source on growth performance and trace element deposition in broilers.A total of 432 Arbor Acres commercial female broilers were fed a basal corn-soybean diet containing Mn at 25.64 mg/kg diet for 10 d.They were then randomly assigned to 6 groups,including a control group(the basal diet),a Mn sulfate group(the basal diet supplemented with Mn at 100 mg/kg diet),and 4 Mn-MHAC groups(the basal diet supplemented with Mn-MHAC at 25,50,75 and 100 mg Mn/kg diet,respectively).The results showed that compared with the control group,groups supplemented with Mn-MHAC had a positive effect on BW(quadratic,P=0.017)and ADG(quadratic,P=0.017).Moreover,the Mn-MHAC(50 mg Mn/kg diet)group had significantly greater BW and ADG(P<0.05)compared with the other Mn-MHAC groups.Trace element deposition results also showed that tibial Mn increased(linear or quadratic,P-0.002 and 0.009,respectively)in groups fed diets with increased levels of Mn-MHAC.In contrast,Fe deposition decreased both in the heart(linear,P-0.020)and tibia(P<0.05).In addition,the Mn-MHAC supplement noticeably lowered serum Mn-SOD activity(linear or quadratic,P-0.048 and 0.019,respectively).The relative mRNA levels of divalent metal transporter 1(DMT1)(P=0.024),ferro-portin 1(FPN1)(P=0.049),and Cu transporter-1(CTR1)(P<0.001)in the duodenum,as well as CTR1 in the jejunum and ileum(P=0.040 and 0.011,respectively)were higher in the Mn-supplemented group than in the control group.Furthermore,the relative mRNA level of DMT1 in the jejunum and ileum of broilers in the Mn-MHAC group(50 mg Mn/kg diet)did not differ from those in the control group,but was lower than those in the Mn sulfate group(P<0.05).In conclusion,Mn-MHAC dietary supplementation improved the growth performance and trace element deposition in broilers.From this study,we recommend the opti-mum Mn-MHAC level to meet the Mn requirement of broilers is 50 to 75 mg Mn/kg diet.
