大剂量甲基泼尼松龙冲击治疗重症特发性血小板减少性紫癜

目的观察大剂量甲基泼尼松龙冲击治疗重症特发性血小板减少性紫癜（ＩＴＰ）的疗效。方法甲基泼尼松龙每天静滴２０～３０ｍｇ·ｋｇ－１，连续３天，继以泼尼松维持，治疗５５例患者。结果５５例患者出血症状得到良好的控制，血小板升高，完全反应率为２５４５％，部分反应率为４５４５％，总有效率为７０９０％；血小板升高时间为４～１４天。结论大剂量甲基泼尼松龙冲击治疗是重症ＩＴＰ患者较安全有效的方法。

^（99m）Tc标单抗在荷人卵巢癌裸鼠体内T／N比值的观察

目的：找出在注射标记抗体的荷瘤裸鼠体内的￣（９９ｍ）Ｔｃ注射剂量、时间与Ｔ／Ｎ比值的关系。方法：用γ计算机和γ计数器测定肿瘤和其它组织的放射性强度，计算Ｔ／Ｎ比值和定位指数ＬＩ．结果：（１）２ｍｃｉ的￣（９９ｍ）Ｔｃ剂量Ｔ／Ｎ比值高；（２）注射标记抗体２８ｈ后，Ｔ／Ｎ比值高，是放免显象的适宜６时间。结论：￣（９９ｍ）Ｔｃ剂量大小与Ｔ／Ｎ比值不呈线性关系，但Ｔ／Ｎ比值与定位指数呈正相关。

CHANGES IN HAIR AND FEATHER ZINC, BONE MAGNESIUM AND POTASSIUM OF ANIMALS FED WITH GOSSYPOL

Yu et al. observed that some trace elements in viscera of rats were changed by treatment of gossypol. In this note, the changes of some metal ions in rat bone and hair and feather of various animals treated with gossypol were determined to observe the influence of gossypol on the metabolism of those elements. Pretreatment of bone, hair and feather and the method of determination were described in the previous paper.