BACKGROUND： It has been found that microRNA-423-5p （miR423-Sp） is an oncogenic factor and frequently upregulated in gastric carcinoma. However, the involvement of miR423- 5p in hepatocellular carcinoma （HCC） has ...BACKGROUND： It has been found that microRNA-423-5p （miR423-Sp） is an oncogenic factor and frequently upregulated in gastric carcinoma. However, the involvement of miR423- 5p in hepatocellular carcinoma （HCC） has been rarely reported. The aim of this study was to assess whether miR423-Sp is aberrantly expressed in HCC tissues, and to characterize its roles in the cancerous biology of HCC.展开更多
基金supported by grants from the Fundamental Research Funds for the Central Universities(2015FZA7013)the Natural Science Foundation of Zhejiang Province(LY15H160021)+3 种基金the National Natural Science Foundation of China(81101840 and 81302074)the Medical Science and Technology Project of Zhejiang Province(201472813)the Medical and Health Platform Backbone Personnel Plan of Zhejiang Province(2012RCB015 and 2013KYB107)the Innovative Research Group of the National Natural Science Foundation of China(81421062)
文摘BACKGROUND： It has been found that microRNA-423-5p （miR423-Sp） is an oncogenic factor and frequently upregulated in gastric carcinoma. However, the involvement of miR423- 5p in hepatocellular carcinoma （HCC） has been rarely reported. The aim of this study was to assess whether miR423-Sp is aberrantly expressed in HCC tissues, and to characterize its roles in the cancerous biology of HCC.
