Radio frequency quadrupoles(RFQs),which are crucial components of proton injectors,significantly affect the performance of proton accelerator facilities.An RFQ with a high frequency of 714 MHz dedicated to compact pro...Radio frequency quadrupoles(RFQs),which are crucial components of proton injectors,significantly affect the performance of proton accelerator facilities.An RFQ with a high frequency of 714 MHz dedicated to compact proton injectors for medi-cal applications is designed in this study.The RFQ is designed to accelerate proton beams from 50 keV to 4 MeV within a short length of 2 m and can be matched closely with the downstream drift tube linac to capture more particles through a preliminary optimization.To develop an advanced RFQ,challenging techniques,including fabrication and tuning method,must be evaluated and verified using a prototype.An aluminium prototype is derived from the conceptual design of the RFQ and then redesigned to confirm the radio frequency performance,fabrication procedure,and feasibility of the tuning algorithm.Eventually,a new tuning algorithm based on the response matrix and least-squares method is developed,which yields favorable results based on the prototype,i.e.,the errors of the dipole and quadrupole components reduced to a low level after several tuning iterations.Benefiting from the conceptual design and techniques obtained from the prototype,the formal mechanical design of the 2-m RFQ is ready for the next manufacturing step.展开更多
The nozzle inner-flow characteristic of the“spray G”injector was studied by the computational fluid dynamics(CFD)simulation,and the sensitivity of cycle fuel mass to the conicity and entrance radius of the nozzle ho...The nozzle inner-flow characteristic of the“spray G”injector was studied by the computational fluid dynamics(CFD)simulation,and the sensitivity of cycle fuel mass to the conicity and entrance radius of the nozzle hole were analyzed.Results show that the inner conicity of nozzle hole inhibits the development of cavitation phenomena,and increases the injection rate.While the outer conicity of nozzle hole promotes the diffusion of cavita-tion,leading to reductions of the liquid volume fraction of the nozzle outlet and the local flow resistance of the nozzle hole.The sensitivity of cycle fuel mass to inner-cone nozzle hole is stronger than that of the outer-cone noz-zle,especially at the smaller hole conicity.The increase of injection pressure enhances the sensitivity of the injection characteristics to the nozzle hole structure,in which inner-cone nozzle has higher sensitivity coefficient than the outer-cone nozzle hole.However,the increase of injection pressure aggravates the offset of liquid jet to the nozzle axis of the outer-cone nozzle hole.With the increase of the inner conicity of nozzle,the sensitivity of the injection characteristics to the entrance radius of the hole decreases.With the increase of the outer conicity of nozzle hole,the sensitivity of the injection characteristics to the entrance radius of the hole increases.展开更多
BACKGROUND To assess the effectiveness of Shugan Jieyu capsules on peripheral blood miR-124,miR-132,and brain-derived neurotrophic factor(BDNF)levels in patients with mild to moderate depression following coronary art...BACKGROUND To assess the effectiveness of Shugan Jieyu capsules on peripheral blood miR-124,miR-132,and brain-derived neurotrophic factor(BDNF)levels in patients with mild to moderate depression following coronary artery intervention[percuta-neous coronary intervention(PCI)]for coronary heart disease.Patients with mild-to-moderate depression of the liver-qi stagnation type after PCI for coronary heart disease at the 305th Hospital of the People’s Liberation Army were enrolled from June 2022 to November 2023 and randomly assigned to two groups:Experimental(treated with Shugan Jieyu capsules)and control(tr-eated with escitalopram oxalate tablets).This study compared the antidepressant effects of these treatments using 17-item Hamilton Rating Scale for Depression(HAMD-17)scores,metabolic equivalents,low-density lipoprotein cholesterol,BDNF,high-sensitivity C-reactive protein levels,miR-124 and miR-132 levels,distribution of immune-related lymphocyte subsets,and traditional Chinese me-dicine syndrome scores before and after 6 weeks of treatment.RESULTS No significant difference was observed in any index between the two groups before treatment(P>0.05).After treatment,the total efficacy rates were 93.33%and 90.00%in the experimental and control groups,respectively.Experimental group had significantly lower scores for the main and secondary syndromes compared to the control group(P<0.05).No significant difference was observed in the metabolic equivalents between the two groups be-fore and after treatment(P>0.05).The levels of low-density lipoprotein cholesterol,high-sensitivity C-reactive pro-tein,and miR-132 were significantly lower,whereas those of miR-124,BDNF,CD3+T lymphocytes,CD3+CD4+T helper lymphocytes,and CD3+CD4+/CD3+CD8+cells were significantly higher in the experimental group com-pared to the control group(P<0.05).The incidence of adverse reactions during experimental group was signi-ficantly lower than that in control group(P<0.05).CONCLUSION Shugan Jieyu capsules have good efficacy in patients with mild-to-moderate depression after PCI,and its me-chanism may contribute to the regulation of miR-124,miR-132,BDNF levels,and lymphoid immune cells.展开更多
Micro- and nano-plastics (MNPs) are tiny plastic particles resulting from plastic product degradation. Soil MNPs have been identified as potential influential factors affecting various soil properties and crop biomass...Micro- and nano-plastics (MNPs) are tiny plastic particles resulting from plastic product degradation. Soil MNPs have been identified as potential influential factors affecting various soil properties and crop biomass productivity. This mini-review provides a synthesis of recent findings concerning their effects on soil physicochemical properties, microorganisms, organic carbon content, soil nutrients, greenhouse gas emissions, soil fauna, and their impacts on plant ecophysiology, growth, and production. The results indicate that MNPs may markedly impede soil aggregation ability, increase porosity, decrease soil bulk density, enhance water retention capacity, influence soil pH and electrical conductivity, and escalate soil water evaporation. Exposure to MNPs may predominantly induce changes in soil microbial composition, reducing the diversity and complexity of microbial communities and microbial activity while enhancing soil organic carbon stability, influencing soil nutrient dynamics, and stimulating organic carbon decomposition and denitrification processes, leading to elevated soil respiration and methane emissions, and potentially decreasing soil nitrous oxide emission. Additionally, MNPs may adversely affect soil fauna, diminish seed germination rates, promote plant root growth, yet impair plant photosynthetic efficacy and biomass productivity. These findings contribute to a better understanding of the impacts and mechanistic foundations of MNPs. Future research avenues are suggested to further explore the impacts and economic implications.展开更多
An air-lift has been more recently applied in the dredging, deep-seated beach placer mining and underground mining engineering. However, the influence and mechanism of various parameters on the air-lift performance ar...An air-lift has been more recently applied in the dredging, deep-seated beach placer mining and underground mining engineering. However, the influence and mechanism of various parameters on the air-lift performance are not quite clear, especially the influence of flow pattern on lifting efficiency. Focusing on the problems mentioned above, the key part of the air-lift (namely, the air injector) was proposed aimed to reduce friction loss in the inner pipe according to improving flow field performance, thus increase the lifting efficiency. The study of relative factors of the performance of an air-lift is performed and the river sand is used as simulation of underground ore bed. The total lifting height of the experimental system is 3 m, the water flux, mass flow of solid particles, concentration of particles and lifting efficiency are measured under the same submergence ratios by changing the air injector, which is divided into nine specifications of air injection in this research. The experimental results indicate that the optimal air flow rate corresponding to excellent performance of the air-lift can be obtained in the range of 35-40 m3/h. The air injection method has a great effect on the performance of the air-lift, the air injector with three nozzles is better than that in the case of one or two nozzles. Further more, the air injection angle and arrangement of air injection pipes also have great effect on the performance of an air-lift. The proposed research results have guiding significance for engineering application.展开更多
The available SMD(Sauter mean diameter) correlations on pressure-swirl injectors predict droplet sizing very different from each other, especially for heavy fuels. Also there was a lack in the literature for comparing...The available SMD(Sauter mean diameter) correlations on pressure-swirl injectors predict droplet sizing very different from each other, especially for heavy fuels. Also there was a lack in the literature for comparing available correlations. So an experimental study was conducted on a heavy fuel oil(HFO) spray, Mazut 380. A pressure swirl injector was designed and fabricated. The experiments for Mazut at 40℃ and 80℃ were compared with the results for water, including spray half cone angle, breakup length and mean droplet diameter,at different injection pressures. Lower spray angle, higher breakup length and larger droplets were observed for lower injection pressures and higher liquid viscosity. SMD was about 75 μm for water and about 87 μm for Mazut at 80℃. The results for droplet mean diameter were also compared with correlations from previous studies on pressure swirl atomizers. The SMD results show that for water spray, LISA method was in good agreement,also Babu and Ballester correlations were successful when high viscosity fluid was injected.展开更多
In the present work, osteoblast behavior on a hierarchical micro-/nano-structured titanium surface was investigated. A hi- erarchical hybrid micro-/nano-structured titanium surface topography was produced via Electrol...In the present work, osteoblast behavior on a hierarchical micro-/nano-structured titanium surface was investigated. A hi- erarchical hybrid micro-/nano-structured titanium surface topography was produced via Electrolytic Etching (EE). MG-63 cells were cultured on disks for 2 h to 7 days. The osteoblast response to the hierarchical hybrid micro-/nano-structured titanium surface was evaluated through the osteoblast cell morphology, attachment and proliferation. For comparison, MG-63 cells were also cultured on Sandblasted and Acid-etched (SEA) as well as Machined (M) surfaces respectively. The results show signifi- cant differences in the adhesion rates and proliferation levels of MG-63 cells on EE, SLA, and M surfaces. Both adhesion rate and proliferation level on EE surface are higher than those on SLA and M surfaces. Therefore, we may expect that, comparing with SLA and M surfaces, bone growth on EE surface could be accelerated and bone formation could be promoted at an early stage, which could be applied in the clinical practices for immediate and early-stage loadings.展开更多
A computational study on the flow behavior of a gas-solid injector by Eulerian approach was carried out. The gas phase was modeled with k-ε turbulent model and the particle phase was modeled with kinetic theory of gr...A computational study on the flow behavior of a gas-solid injector by Eulerian approach was carried out. The gas phase was modeled with k-ε turbulent model and the particle phase was modeled with kinetic theory of granular flow. The simulations by Eulerian two-fluid model (TFM) were compared with the corresponding results by discrete element method (DEM) and experiments. It was showed that TFM simulated results were in reasonable agreement with the experimental and DEM simulated results. Based on TFM simulations, gas-solid flow pattern, gas velocity, particle velocity and the static pressure under different driving jet velocity, backpressure and convergent section angle were obtained. The results showed that the time average axial gas velocity sharply decreased and then slightly increased to a constant value in the horizontal conveying pipe. The time average axial particle velocity increased initially and then decreased, but in the outlet region of the convergent section the particle velocity remarkably increased once more to the maximal value. As a whole, the static pressure distribution change trends were found to be independent on driving gas velocity, backpressure and convergent section angle. However, the static pressure increased with increase of convergent section angle and gas jet velocities. The difference of static pressure to backpressure increased with increasing backpressure.展开更多
In this paper,macro-and micro-properties of natural marine clay in two different and representative regions of China are investigated in detail.In addition to in-situ tests,soil samples are collected by use of Shelby ...In this paper,macro-and micro-properties of natural marine clay in two different and representative regions of China are investigated in detail.In addition to in-situ tests,soil samples are collected by use of Shelby tubes for laboratory examination in Shanghai and Zhuhai respectively,two coastal cities in China.In the laboratory tests,macro-properties such as consolidation characteristics and undrained shear strength are measured.Moreover,X-ray diffraction test,scanning electron microscope test,and mercury intrusion test are carried out for the investigation of their micro-properties including clay minerals and microstructure.The study shows that:(1)both clays are Holocene series formations,classified as either normal or underconsolidated soils.The initial gradient of the stress-strain curves shows their increase with increasing consolidation pressure;however,the Shanghai and the Zhuhai clays are both structural soils with the latter shown to be more structured than the former.As a result,the Zhuhai clay shows strain softening behavior at low confining pressures,but strain hardening at high pressures.In contrast,the Shanghai clay mainly manifests strain-hardening.(2)An activity ranges from 0.75 to 1.30 for the Shanghai marine clay and from 0.5 to 0.85 for the Zhuhai marine clay.The main clay mineral is illite in the Shanghai clay and kaolinite in the Zhuhai clay.The Zhuhai clay is mainly characterized by a flocculated structure,while the typical Shanghai clay shows a dispersed structure.The porous structure of the Shanghai clay is characterized mainly by large and medium-sized pores,while the Zhuhai clay porous structure is mainly featured by small and medium-sized pores.The differences in their macro-and micro-properties can be attributed to different sedimentation environments.展开更多
A compact interdigital H-mode drift-tube linac (IH-DTL) with the alternating-phase-focusing (APF) method, working at 325 MHz was designed for an injector of a proton medical accelerator. When fed in with a proper RF (...A compact interdigital H-mode drift-tube linac (IH-DTL) with the alternating-phase-focusing (APF) method, working at 325 MHz was designed for an injector of a proton medical accelerator. When fed in with a proper RF (radio frequency) power, the DTL cavity could establish the corresponding electromagnetic field to accelerate the ‘‘proton bunches’’ from an input energy of 3 MeV to an output energy of 7 MeV successfully, without any additional radial focusing elements. The gap-voltage distribution which was obtained from the CST■ Microwave Studio software simulations of the axial electric field was compared with that from the beam dynamics, and the errors met the requirements within ± 5%. In this paper, the RF design procedure and key results of the APF IH-DTL, which include the main RF characteristics of the cavity, frequency sensitivities of the tuners, and coupling factor of the RF power input coupler are presented.展开更多
Versatile liquid manipulating surfaces combining patternable and controllable wettability have recently motivated considerable attention owing to their significant advantages in droplet-solid impacting behaviors,micro...Versatile liquid manipulating surfaces combining patternable and controllable wettability have recently motivated considerable attention owing to their significant advantages in droplet-solid impacting behaviors,microdroplet self-removal,and liquid–liquid interface reaction applications.However,developing a facile and efficient method to fabricate these versatile surfaces remains an enormous challenge.In this paper,a strategy for the fabrication of liquid manipulating surfaces with patternable and controllable wettability on Polyimide(PI)film based on femtosecond laser thermal accumulation engineering is proposed.Because of its controllable micro-/nanostructures and chemical composition through adjusting the local thermal accumulation,the wettability of PI film can be tuned from superhydrophilicity(~3.6°)to superhydrophobicity(~151.6°).Furthermore,three diverse surfaces with patternable and heterogeneous wettability were constructed and various applications were successfully realized,including water transport,droplet arrays,and liquid wells.This work may provide a facile strategy for achieving patternable and controllable wettability efficiently and developing multifunctional liquid steering surfaces.展开更多
As one of the most effective methods for plasma heating,a neutral beam injector(NBI) achieved plasma heating and current driving for the first time in EAST 2014 experimental campaign.According to the research plan o...As one of the most effective methods for plasma heating,a neutral beam injector(NBI) achieved plasma heating and current driving for the first time in EAST 2014 experimental campaign.According to the research plan of the EAST physics experiment,the first NBI(EASTNBI-1) has been built and become operational in 2014.In this article,the latest experiment results of EAST-NBI-1 are reported as follows:(1) EAST achieves H-mode plasma in the case of NBI heating alone,(2) EAST achieves 22 s long pulse stable H-mode plasma in the case of sinndtaneous NBI and lower hybrid wave(LHW) heating.The measurement data show that the loop voltage decreased and the plasma stored energy increased obviously.The results indicate that EAST-NBI-1 has achieved plasma heating and current driving,and thus lays a foundation for the construction of EAST-NBI-2,which will be built in a few months this year.展开更多
The physical model of -20 diesel oil and force model of injector controlvalve of common rail system is built. The changes of the fluid thickness are investigated on thebase of the results of CFD and experiments for co...The physical model of -20 diesel oil and force model of injector controlvalve of common rail system is built. The changes of the fluid thickness are investigated on thebase of the results of CFD and experiments for control valve of injector. The results indicate thata fluid thickness of 0.02-0.03 mm between the poppet and valve guide is sufficient to dampen anyexcessive control valve poppet bouncing.展开更多
Treatment of petroleum spills and organic solvent pollution in general is an important issue; several techniques are under development to remove oil from water. The use of absorbents is one of the most common techniqu...Treatment of petroleum spills and organic solvent pollution in general is an important issue; several techniques are under development to remove oil from water. The use of absorbents is one of the most common techniques to tackle this problem. These absorbents can be classified based on their characteristics of recyclability into irreversible and reversible ones. In this review, we discuss the application of several materials as oil absorbents, according to their classification and characteristics such as hydrophobicity, surface area and oil absorption capacity. Also, the fabrication methods for some materials are presented and analyzed.展开更多
In order to synchronize the elements of the EAST Neutral Beam Injector (NBI) spatially located in several places, a distributed Timing System (TS) is developed in this paper. The timing system provides a clock ref...In order to synchronize the elements of the EAST Neutral Beam Injector (NBI) spatially located in several places, a distributed Timing System (TS) is developed in this paper. The timing system provides a clock reference for synchronization and an interlock protection of the EAST NBI system. It sends timing signals to field devices, controls the pulse widths of the timing sequences, and provides a sampling clock for the Data Acquisition System (DAS). The timing system also generates analog waveforms to control power supplies and gas supplies according to the operator's configuration. The timing system is developed on a PXI (PCI eXtensions for Instrumentation) platform consisting of a LabVIEW workstation and a timing control terminal. The timing control terminal consists of a timing node and several control interface crates. Two timing nodes are configured in one beam line. Each node is responsible for the timing sequence, analog generation and feedback control for one ion source. The architecture and implementation of the timing system are presented in this paper.展开更多
Influence of eddy current on transient characteristics of common rail injector solenoid valve was studied in this paper. Experimental investigations of drive current and power source volt- age of both drive current as...Influence of eddy current on transient characteristics of common rail injector solenoid valve was studied in this paper. Experimental investigations of drive current and power source volt- age of both drive current ascending and descending process were conducted on a common rail injec- tor solenoid valve. A new discretizing calculation method of solenoid valve flux linkage was put for- ward for the first time based on the experimental results and drive circuit principle, and flux linkage of both drive current ascending and descending process were evaluated. New inductance calculation methods for drive current ascending and descending process respectively were also presented. Influ- ence of parasitic inductance was evaluated. Results indicate that the air gap, under which the transi- ent flux linkage of the solenoid valve is the biggest, varies with drive current due to eddy current. Flux linkage of drive current descending process is bigger than that of drive current ascending process under the same drive current and the same air gap width. Eddy current can reduce the delay between the time that drive current begins to descend and the time that armature begins to move downward. Inductance of drive current descending process is bigger than that of drive current as- cending process over larger scope of drive current, but the difference becomes smaller with the in- creasing of air gap width. The differences of both flux linkage and inductance between drive current ascending and descending process are caused by the eddy current in core and armature materials.展开更多
In this research, pulverization plate and base of a fuel injector in an automobile electronic-controlled engine was joined by pulsed laser welding. The different welding parameters were evaluated and effect of process...In this research, pulverization plate and base of a fuel injector in an automobile electronic-controlled engine was joined by pulsed laser welding. The different welding parameters were evaluated and effect of process parameters on joint characteristics was analyzed. The optimal process parameters were obtained as follows: welding current 120 A, welding speed 600 ram/rain, pulse duration 1.80 ms and pulse frequency 60 Hz. The microstructure of weld metal was investigated. Results show that the fusion zone is austenitic dendrite, the weld center is equiaxed grain, while the transition zone between fusion zone and weld center is mixed crystal with austenitic dendrite and equiaxed grain. The weld layered phenomenon was observed, and eddy caused by keyhole effect is the main reason for the formation of layered structure in molten pool.展开更多
PT fuel injector is one of the most important parts of modern diesel engine.To satisfy the requirements of the rapid and accurate test of PT fuel injector,the self-adaptive floating clamping mechanism was developed an...PT fuel injector is one of the most important parts of modern diesel engine.To satisfy the requirements of the rapid and accurate test of PT fuel injector,the self-adaptive floating clamping mechanism was developed and used in the relevant bench.Its dynamic characteristics directly influence the test efficiency and accuracy.However,due to its special structure and complex oil pressure signal,related documents for evaluating dynamic characteristics of this mechanism are lack and some dynamic characteristics of this mechanism can't be extracted and recognized effectively by traditional methods.Aiming at the problem above-mentioned,a new method based on Hilbert-Huang transform(HHT) is presented.Firstly,combining with the actual working process,the dynamic liquid pressure signal of the mechanism is acquired.By analyzing the pressure fluctuation during the whole working process in time domain,oil leakage and hydraulic shock in the clamping chamber are discovered.Secondly,owing to the nonlinearity and nonstationarity of pressure signal,empirical mode decomposition is used,and the signal is decomposed and reconstructed into forced vibration,free vibration and noise.By analyzing forced vibration in the time domain,machining error and installation error of cam are revealed.Finally,free vibration component is analyzed in time-frequency domain with HHT,the traits of free vibration in the time-frequency domain are revealed.Compared with traditional methods,Hilbert spectrum has higher time-frequency resolutions and higher credibility.The improved mechanism based on the above analyses can guarantee the test accuracy of injector injection.This new method based on the analyses of the pressure signal and combined with HHT can provide scientific basis for evaluation,design improvement of the mechanism,and give references for dynamic characteristics analysis of the hydraulic system in the interrelated fields.展开更多
基金This work was supported by National Natural Science Foundation of China(No.12222513).
文摘Radio frequency quadrupoles(RFQs),which are crucial components of proton injectors,significantly affect the performance of proton accelerator facilities.An RFQ with a high frequency of 714 MHz dedicated to compact proton injectors for medi-cal applications is designed in this study.The RFQ is designed to accelerate proton beams from 50 keV to 4 MeV within a short length of 2 m and can be matched closely with the downstream drift tube linac to capture more particles through a preliminary optimization.To develop an advanced RFQ,challenging techniques,including fabrication and tuning method,must be evaluated and verified using a prototype.An aluminium prototype is derived from the conceptual design of the RFQ and then redesigned to confirm the radio frequency performance,fabrication procedure,and feasibility of the tuning algorithm.Eventually,a new tuning algorithm based on the response matrix and least-squares method is developed,which yields favorable results based on the prototype,i.e.,the errors of the dipole and quadrupole components reduced to a low level after several tuning iterations.Benefiting from the conceptual design and techniques obtained from the prototype,the formal mechanical design of the 2-m RFQ is ready for the next manufacturing step.
文摘The nozzle inner-flow characteristic of the“spray G”injector was studied by the computational fluid dynamics(CFD)simulation,and the sensitivity of cycle fuel mass to the conicity and entrance radius of the nozzle hole were analyzed.Results show that the inner conicity of nozzle hole inhibits the development of cavitation phenomena,and increases the injection rate.While the outer conicity of nozzle hole promotes the diffusion of cavita-tion,leading to reductions of the liquid volume fraction of the nozzle outlet and the local flow resistance of the nozzle hole.The sensitivity of cycle fuel mass to inner-cone nozzle hole is stronger than that of the outer-cone noz-zle,especially at the smaller hole conicity.The increase of injection pressure enhances the sensitivity of the injection characteristics to the nozzle hole structure,in which inner-cone nozzle has higher sensitivity coefficient than the outer-cone nozzle hole.However,the increase of injection pressure aggravates the offset of liquid jet to the nozzle axis of the outer-cone nozzle hole.With the increase of the inner conicity of nozzle,the sensitivity of the injection characteristics to the entrance radius of the hole decreases.With the increase of the outer conicity of nozzle hole,the sensitivity of the injection characteristics to the entrance radius of the hole increases.
基金the 305 Hospital Independent Scientific Research Fund,2024,No.24ZZJJLW-022.
文摘BACKGROUND To assess the effectiveness of Shugan Jieyu capsules on peripheral blood miR-124,miR-132,and brain-derived neurotrophic factor(BDNF)levels in patients with mild to moderate depression following coronary artery intervention[percuta-neous coronary intervention(PCI)]for coronary heart disease.Patients with mild-to-moderate depression of the liver-qi stagnation type after PCI for coronary heart disease at the 305th Hospital of the People’s Liberation Army were enrolled from June 2022 to November 2023 and randomly assigned to two groups:Experimental(treated with Shugan Jieyu capsules)and control(tr-eated with escitalopram oxalate tablets).This study compared the antidepressant effects of these treatments using 17-item Hamilton Rating Scale for Depression(HAMD-17)scores,metabolic equivalents,low-density lipoprotein cholesterol,BDNF,high-sensitivity C-reactive protein levels,miR-124 and miR-132 levels,distribution of immune-related lymphocyte subsets,and traditional Chinese me-dicine syndrome scores before and after 6 weeks of treatment.RESULTS No significant difference was observed in any index between the two groups before treatment(P>0.05).After treatment,the total efficacy rates were 93.33%and 90.00%in the experimental and control groups,respectively.Experimental group had significantly lower scores for the main and secondary syndromes compared to the control group(P<0.05).No significant difference was observed in the metabolic equivalents between the two groups be-fore and after treatment(P>0.05).The levels of low-density lipoprotein cholesterol,high-sensitivity C-reactive pro-tein,and miR-132 were significantly lower,whereas those of miR-124,BDNF,CD3+T lymphocytes,CD3+CD4+T helper lymphocytes,and CD3+CD4+/CD3+CD8+cells were significantly higher in the experimental group com-pared to the control group(P<0.05).The incidence of adverse reactions during experimental group was signi-ficantly lower than that in control group(P<0.05).CONCLUSION Shugan Jieyu capsules have good efficacy in patients with mild-to-moderate depression after PCI,and its me-chanism may contribute to the regulation of miR-124,miR-132,BDNF levels,and lymphoid immune cells.
文摘Micro- and nano-plastics (MNPs) are tiny plastic particles resulting from plastic product degradation. Soil MNPs have been identified as potential influential factors affecting various soil properties and crop biomass productivity. This mini-review provides a synthesis of recent findings concerning their effects on soil physicochemical properties, microorganisms, organic carbon content, soil nutrients, greenhouse gas emissions, soil fauna, and their impacts on plant ecophysiology, growth, and production. The results indicate that MNPs may markedly impede soil aggregation ability, increase porosity, decrease soil bulk density, enhance water retention capacity, influence soil pH and electrical conductivity, and escalate soil water evaporation. Exposure to MNPs may predominantly induce changes in soil microbial composition, reducing the diversity and complexity of microbial communities and microbial activity while enhancing soil organic carbon stability, influencing soil nutrient dynamics, and stimulating organic carbon decomposition and denitrification processes, leading to elevated soil respiration and methane emissions, and potentially decreasing soil nitrous oxide emission. Additionally, MNPs may adversely affect soil fauna, diminish seed germination rates, promote plant root growth, yet impair plant photosynthetic efficacy and biomass productivity. These findings contribute to a better understanding of the impacts and mechanistic foundations of MNPs. Future research avenues are suggested to further explore the impacts and economic implications.
基金supported by Ministry of Science and Technology of China (Grant No. 2008DFA70300)
文摘An air-lift has been more recently applied in the dredging, deep-seated beach placer mining and underground mining engineering. However, the influence and mechanism of various parameters on the air-lift performance are not quite clear, especially the influence of flow pattern on lifting efficiency. Focusing on the problems mentioned above, the key part of the air-lift (namely, the air injector) was proposed aimed to reduce friction loss in the inner pipe according to improving flow field performance, thus increase the lifting efficiency. The study of relative factors of the performance of an air-lift is performed and the river sand is used as simulation of underground ore bed. The total lifting height of the experimental system is 3 m, the water flux, mass flow of solid particles, concentration of particles and lifting efficiency are measured under the same submergence ratios by changing the air injector, which is divided into nine specifications of air injection in this research. The experimental results indicate that the optimal air flow rate corresponding to excellent performance of the air-lift can be obtained in the range of 35-40 m3/h. The air injection method has a great effect on the performance of the air-lift, the air injector with three nozzles is better than that in the case of one or two nozzles. Further more, the air injection angle and arrangement of air injection pipes also have great effect on the performance of an air-lift. The proposed research results have guiding significance for engineering application.
文摘The available SMD(Sauter mean diameter) correlations on pressure-swirl injectors predict droplet sizing very different from each other, especially for heavy fuels. Also there was a lack in the literature for comparing available correlations. So an experimental study was conducted on a heavy fuel oil(HFO) spray, Mazut 380. A pressure swirl injector was designed and fabricated. The experiments for Mazut at 40℃ and 80℃ were compared with the results for water, including spray half cone angle, breakup length and mean droplet diameter,at different injection pressures. Lower spray angle, higher breakup length and larger droplets were observed for lower injection pressures and higher liquid viscosity. SMD was about 75 μm for water and about 87 μm for Mazut at 80℃. The results for droplet mean diameter were also compared with correlations from previous studies on pressure swirl atomizers. The SMD results show that for water spray, LISA method was in good agreement,also Babu and Ballester correlations were successful when high viscosity fluid was injected.
文摘In the present work, osteoblast behavior on a hierarchical micro-/nano-structured titanium surface was investigated. A hi- erarchical hybrid micro-/nano-structured titanium surface topography was produced via Electrolytic Etching (EE). MG-63 cells were cultured on disks for 2 h to 7 days. The osteoblast response to the hierarchical hybrid micro-/nano-structured titanium surface was evaluated through the osteoblast cell morphology, attachment and proliferation. For comparison, MG-63 cells were also cultured on Sandblasted and Acid-etched (SEA) as well as Machined (M) surfaces respectively. The results show signifi- cant differences in the adhesion rates and proliferation levels of MG-63 cells on EE, SLA, and M surfaces. Both adhesion rate and proliferation level on EE surface are higher than those on SLA and M surfaces. Therefore, we may expect that, comparing with SLA and M surfaces, bone growth on EE surface could be accelerated and bone formation could be promoted at an early stage, which could be applied in the clinical practices for immediate and early-stage loadings.
基金Supported by the National High Technology Research and Development Program of China (2006AA05A103), the National Natural Science Foundation of China (50706007), Foundation of Graduate Creative Program of Jiangsu (CX08B-060Z), and the Foundation for Excellent Ph.D. Thesis of Southeast University. ACKNOWLEDGEMENTS The authors also expressed sincere gratitude to Professors M. Horio, B. Leckner, A. Kane and E.J. Anthony for constructive advice during their visiting period in Southeast University, which contributed to our research.
文摘A computational study on the flow behavior of a gas-solid injector by Eulerian approach was carried out. The gas phase was modeled with k-ε turbulent model and the particle phase was modeled with kinetic theory of granular flow. The simulations by Eulerian two-fluid model (TFM) were compared with the corresponding results by discrete element method (DEM) and experiments. It was showed that TFM simulated results were in reasonable agreement with the experimental and DEM simulated results. Based on TFM simulations, gas-solid flow pattern, gas velocity, particle velocity and the static pressure under different driving jet velocity, backpressure and convergent section angle were obtained. The results showed that the time average axial gas velocity sharply decreased and then slightly increased to a constant value in the horizontal conveying pipe. The time average axial particle velocity increased initially and then decreased, but in the outlet region of the convergent section the particle velocity remarkably increased once more to the maximal value. As a whole, the static pressure distribution change trends were found to be independent on driving gas velocity, backpressure and convergent section angle. However, the static pressure increased with increase of convergent section angle and gas jet velocities. The difference of static pressure to backpressure increased with increasing backpressure.
基金supported bythe National Natural Science Foundation of China(Grant No.50679057)the National High Technology Research and Development Program of China(863 Program,Grnat No.2006AA11Z102)+1 种基金the Shanghai Pujiang Program(Grant No.06PJ14088)the Zhuhai city Science Technology Program(Grant No.PA200310064)
文摘In this paper,macro-and micro-properties of natural marine clay in two different and representative regions of China are investigated in detail.In addition to in-situ tests,soil samples are collected by use of Shelby tubes for laboratory examination in Shanghai and Zhuhai respectively,two coastal cities in China.In the laboratory tests,macro-properties such as consolidation characteristics and undrained shear strength are measured.Moreover,X-ray diffraction test,scanning electron microscope test,and mercury intrusion test are carried out for the investigation of their micro-properties including clay minerals and microstructure.The study shows that:(1)both clays are Holocene series formations,classified as either normal or underconsolidated soils.The initial gradient of the stress-strain curves shows their increase with increasing consolidation pressure;however,the Shanghai and the Zhuhai clays are both structural soils with the latter shown to be more structured than the former.As a result,the Zhuhai clay shows strain softening behavior at low confining pressures,but strain hardening at high pressures.In contrast,the Shanghai clay mainly manifests strain-hardening.(2)An activity ranges from 0.75 to 1.30 for the Shanghai marine clay and from 0.5 to 0.85 for the Zhuhai marine clay.The main clay mineral is illite in the Shanghai clay and kaolinite in the Zhuhai clay.The Zhuhai clay is mainly characterized by a flocculated structure,while the typical Shanghai clay shows a dispersed structure.The porous structure of the Shanghai clay is characterized mainly by large and medium-sized pores,while the Zhuhai clay porous structure is mainly featured by small and medium-sized pores.The differences in their macro-and micro-properties can be attributed to different sedimentation environments.
基金supported by the National Key Research and Development Program of China(No.2016YFC0105408)
文摘A compact interdigital H-mode drift-tube linac (IH-DTL) with the alternating-phase-focusing (APF) method, working at 325 MHz was designed for an injector of a proton medical accelerator. When fed in with a proper RF (radio frequency) power, the DTL cavity could establish the corresponding electromagnetic field to accelerate the ‘‘proton bunches’’ from an input energy of 3 MeV to an output energy of 7 MeV successfully, without any additional radial focusing elements. The gap-voltage distribution which was obtained from the CST■ Microwave Studio software simulations of the axial electric field was compared with that from the beam dynamics, and the errors met the requirements within ± 5%. In this paper, the RF design procedure and key results of the APF IH-DTL, which include the main RF characteristics of the cavity, frequency sensitivities of the tuners, and coupling factor of the RF power input coupler are presented.
基金This research is supported by National Natural Science Foundation of China(Nos.52075557,51805553)Natural Science Foundation of Hunan Province(No.2021JJ20067)+1 种基金The Science and Technology Innovation Program of Hunan Province(No.2021RC3011)Open access funding provided by Shanghai Jiao Tong University
文摘Versatile liquid manipulating surfaces combining patternable and controllable wettability have recently motivated considerable attention owing to their significant advantages in droplet-solid impacting behaviors,microdroplet self-removal,and liquid–liquid interface reaction applications.However,developing a facile and efficient method to fabricate these versatile surfaces remains an enormous challenge.In this paper,a strategy for the fabrication of liquid manipulating surfaces with patternable and controllable wettability on Polyimide(PI)film based on femtosecond laser thermal accumulation engineering is proposed.Because of its controllable micro-/nanostructures and chemical composition through adjusting the local thermal accumulation,the wettability of PI film can be tuned from superhydrophilicity(~3.6°)to superhydrophobicity(~151.6°).Furthermore,three diverse surfaces with patternable and heterogeneous wettability were constructed and various applications were successfully realized,including water transport,droplet arrays,and liquid wells.This work may provide a facile strategy for achieving patternable and controllable wettability efficiently and developing multifunctional liquid steering surfaces.
基金supported by the National Magnetic Confinement Fusion Science Program of China(No.2013GB101000)
文摘As one of the most effective methods for plasma heating,a neutral beam injector(NBI) achieved plasma heating and current driving for the first time in EAST 2014 experimental campaign.According to the research plan of the EAST physics experiment,the first NBI(EASTNBI-1) has been built and become operational in 2014.In this article,the latest experiment results of EAST-NBI-1 are reported as follows:(1) EAST achieves H-mode plasma in the case of NBI heating alone,(2) EAST achieves 22 s long pulse stable H-mode plasma in the case of sinndtaneous NBI and lower hybrid wave(LHW) heating.The measurement data show that the loop voltage decreased and the plasma stored energy increased obviously.The results indicate that EAST-NBI-1 has achieved plasma heating and current driving,and thus lays a foundation for the construction of EAST-NBI-2,which will be built in a few months this year.
文摘The physical model of -20 diesel oil and force model of injector controlvalve of common rail system is built. The changes of the fluid thickness are investigated on thebase of the results of CFD and experiments for control valve of injector. The results indicate thata fluid thickness of 0.02-0.03 mm between the poppet and valve guide is sufficient to dampen anyexcessive control valve poppet bouncing.
基金the Universidad Autónoma de Nuevo León (Monterrey city, Mexico) for financial support (Project Paicyt-2015)
文摘Treatment of petroleum spills and organic solvent pollution in general is an important issue; several techniques are under development to remove oil from water. The use of absorbents is one of the most common techniques to tackle this problem. These absorbents can be classified based on their characteristics of recyclability into irreversible and reversible ones. In this review, we discuss the application of several materials as oil absorbents, according to their classification and characteristics such as hydrophobicity, surface area and oil absorption capacity. Also, the fabrication methods for some materials are presented and analyzed.
文摘In order to synchronize the elements of the EAST Neutral Beam Injector (NBI) spatially located in several places, a distributed Timing System (TS) is developed in this paper. The timing system provides a clock reference for synchronization and an interlock protection of the EAST NBI system. It sends timing signals to field devices, controls the pulse widths of the timing sequences, and provides a sampling clock for the Data Acquisition System (DAS). The timing system also generates analog waveforms to control power supplies and gas supplies according to the operator's configuration. The timing system is developed on a PXI (PCI eXtensions for Instrumentation) platform consisting of a LabVIEW workstation and a timing control terminal. The timing control terminal consists of a timing node and several control interface crates. Two timing nodes are configured in one beam line. Each node is responsible for the timing sequence, analog generation and feedback control for one ion source. The architecture and implementation of the timing system are presented in this paper.
基金Supported by the National Natural Science Foundation of China(51076014)the Research Fund for the Doctoral Program of Higher Education(20101101110011)
文摘Influence of eddy current on transient characteristics of common rail injector solenoid valve was studied in this paper. Experimental investigations of drive current and power source volt- age of both drive current ascending and descending process were conducted on a common rail injec- tor solenoid valve. A new discretizing calculation method of solenoid valve flux linkage was put for- ward for the first time based on the experimental results and drive circuit principle, and flux linkage of both drive current ascending and descending process were evaluated. New inductance calculation methods for drive current ascending and descending process respectively were also presented. Influ- ence of parasitic inductance was evaluated. Results indicate that the air gap, under which the transi- ent flux linkage of the solenoid valve is the biggest, varies with drive current due to eddy current. Flux linkage of drive current descending process is bigger than that of drive current ascending process under the same drive current and the same air gap width. Eddy current can reduce the delay between the time that drive current begins to descend and the time that armature begins to move downward. Inductance of drive current descending process is bigger than that of drive current as- cending process over larger scope of drive current, but the difference becomes smaller with the in- creasing of air gap width. The differences of both flux linkage and inductance between drive current ascending and descending process are caused by the eddy current in core and armature materials.
文摘In this research, pulverization plate and base of a fuel injector in an automobile electronic-controlled engine was joined by pulsed laser welding. The different welding parameters were evaluated and effect of process parameters on joint characteristics was analyzed. The optimal process parameters were obtained as follows: welding current 120 A, welding speed 600 ram/rain, pulse duration 1.80 ms and pulse frequency 60 Hz. The microstructure of weld metal was investigated. Results show that the fusion zone is austenitic dendrite, the weld center is equiaxed grain, while the transition zone between fusion zone and weld center is mixed crystal with austenitic dendrite and equiaxed grain. The weld layered phenomenon was observed, and eddy caused by keyhole effect is the main reason for the formation of layered structure in molten pool.
文摘PT fuel injector is one of the most important parts of modern diesel engine.To satisfy the requirements of the rapid and accurate test of PT fuel injector,the self-adaptive floating clamping mechanism was developed and used in the relevant bench.Its dynamic characteristics directly influence the test efficiency and accuracy.However,due to its special structure and complex oil pressure signal,related documents for evaluating dynamic characteristics of this mechanism are lack and some dynamic characteristics of this mechanism can't be extracted and recognized effectively by traditional methods.Aiming at the problem above-mentioned,a new method based on Hilbert-Huang transform(HHT) is presented.Firstly,combining with the actual working process,the dynamic liquid pressure signal of the mechanism is acquired.By analyzing the pressure fluctuation during the whole working process in time domain,oil leakage and hydraulic shock in the clamping chamber are discovered.Secondly,owing to the nonlinearity and nonstationarity of pressure signal,empirical mode decomposition is used,and the signal is decomposed and reconstructed into forced vibration,free vibration and noise.By analyzing forced vibration in the time domain,machining error and installation error of cam are revealed.Finally,free vibration component is analyzed in time-frequency domain with HHT,the traits of free vibration in the time-frequency domain are revealed.Compared with traditional methods,Hilbert spectrum has higher time-frequency resolutions and higher credibility.The improved mechanism based on the above analyses can guarantee the test accuracy of injector injection.This new method based on the analyses of the pressure signal and combined with HHT can provide scientific basis for evaluation,design improvement of the mechanism,and give references for dynamic characteristics analysis of the hydraulic system in the interrelated fields.