A method of determining branching parameter of lacquer polysaccharide wasestablished by acid-base back-titration of terminal uronic acid of branches. The branchingfactors obtained are in agreement with the values dete...A method of determining branching parameter of lacquer polysaccharide wasestablished by acid-base back-titration of terminal uronic acid of branches. The branchingfactors obtained are in agreement with the values determined by colorimetric method withcarbazole and the results estimated by using Zimm-Stockmayer equation from viscositydata. Influences of molecular weights and branching factors of five fractions of lacquerpolysaccharide on the bioactivities were studied. The results show that the polysaccharideshave bioactivities in motivating the growth of leucocytes, and the effect increases with thedecrease of molecular weight and branching factor in the range studied (17×10~4 >M_w>4×10~4).展开更多
目的探讨不同浓度低分子肝素对PICC相关性血栓(catheter related thrombosis,CRT)形成的抑制作用。方法将40只实验兔按随机数字表法分为A组(对照组)、B组(低浓度低分子肝素组)、C组(中浓度低分子肝素组)、D组(高浓度低分子肝素组),成功...目的探讨不同浓度低分子肝素对PICC相关性血栓(catheter related thrombosis,CRT)形成的抑制作用。方法将40只实验兔按随机数字表法分为A组(对照组)、B组(低浓度低分子肝素组)、C组(中浓度低分子肝素组)、D组(高浓度低分子肝素组),成功建立PICC实验兔模型后,分别用0.9%氯化钠溶液、50μ/(mL·d)低分子肝素钠溶液、100μ/(mL·d)低分子肝素钠溶液、200μ/(mL·d)低分子肝素钠溶液在实验兔腹部进行皮下注射,每日1次连续7 d。截取耳缘静脉、前腔静脉以及PICC导管进行HE染色,光镜下观察并比较四组实验兔不同部位的CRT发生率以及凝血功能情况。结果A组CRT发生率为100%,D组无血栓发生,A组与其它三组间血栓发生率比较差异有统计学意义(P<0.01)。其中,A组、B组、C组实验兔耳缘静脉血栓发生率与D组比较差异有统计学意义(P<0.01)。A组、B组的PICC导管血栓发生率与C组、D组间比较差异有统计学意义(P<0.01)。PICC置管一周后,血PT、APTT、TT、FIB、D-D二聚体含量在各组间比较差异有统计学意义(P<0.01)。结论不同浓度低分子肝素对CRT形成有预防作用,且随着浓度的递升作用渐增,其中高浓度低分子肝素200μ/(mL·d)可有效预防CRT形成并降低发生率,具有重要的临床意义。展开更多
The copolymerization of styrene (St) and acrylonitrile (AN) complexed with CuCl_2 monomer by a free radicalmechanism was performed using benzoyl peroxide as an initiator at 65℃ under N_2 atmosphere for 150 min. The r...The copolymerization of styrene (St) and acrylonitrile (AN) complexed with CuCl_2 monomer by a free radicalmechanism was performed using benzoyl peroxide as an initiator at 65℃ under N_2 atmosphere for 150 min. The rate ofpolymerization (R_p) was found to increase linearly with the concentration (in mol/L) of CuCl_2, AN and St through scalingrelations. The activation energy of the copolymerization process in the presence and absence of CuCl_2 was found to be46.5 kJ/mol and 102 kJ/mol, respectively. The viscosity average molecular weigh of the copolymer and the k_p^2/k_t ratio weredctermired to further assess the accelerating effect of CuCl_2 on the copolymerization process. The copolymerization processin the presence of CuCl_2 has a radical complex mechanism.展开更多
文摘A method of determining branching parameter of lacquer polysaccharide wasestablished by acid-base back-titration of terminal uronic acid of branches. The branchingfactors obtained are in agreement with the values determined by colorimetric method withcarbazole and the results estimated by using Zimm-Stockmayer equation from viscositydata. Influences of molecular weights and branching factors of five fractions of lacquerpolysaccharide on the bioactivities were studied. The results show that the polysaccharideshave bioactivities in motivating the growth of leucocytes, and the effect increases with thedecrease of molecular weight and branching factor in the range studied (17×10~4 >M_w>4×10~4).
文摘目的探讨不同浓度低分子肝素对PICC相关性血栓(catheter related thrombosis,CRT)形成的抑制作用。方法将40只实验兔按随机数字表法分为A组(对照组)、B组(低浓度低分子肝素组)、C组(中浓度低分子肝素组)、D组(高浓度低分子肝素组),成功建立PICC实验兔模型后,分别用0.9%氯化钠溶液、50μ/(mL·d)低分子肝素钠溶液、100μ/(mL·d)低分子肝素钠溶液、200μ/(mL·d)低分子肝素钠溶液在实验兔腹部进行皮下注射,每日1次连续7 d。截取耳缘静脉、前腔静脉以及PICC导管进行HE染色,光镜下观察并比较四组实验兔不同部位的CRT发生率以及凝血功能情况。结果A组CRT发生率为100%,D组无血栓发生,A组与其它三组间血栓发生率比较差异有统计学意义(P<0.01)。其中,A组、B组、C组实验兔耳缘静脉血栓发生率与D组比较差异有统计学意义(P<0.01)。A组、B组的PICC导管血栓发生率与C组、D组间比较差异有统计学意义(P<0.01)。PICC置管一周后,血PT、APTT、TT、FIB、D-D二聚体含量在各组间比较差异有统计学意义(P<0.01)。结论不同浓度低分子肝素对CRT形成有预防作用,且随着浓度的递升作用渐增,其中高浓度低分子肝素200μ/(mL·d)可有效预防CRT形成并降低发生率,具有重要的临床意义。
文摘The copolymerization of styrene (St) and acrylonitrile (AN) complexed with CuCl_2 monomer by a free radicalmechanism was performed using benzoyl peroxide as an initiator at 65℃ under N_2 atmosphere for 150 min. The rate ofpolymerization (R_p) was found to increase linearly with the concentration (in mol/L) of CuCl_2, AN and St through scalingrelations. The activation energy of the copolymerization process in the presence and absence of CuCl_2 was found to be46.5 kJ/mol and 102 kJ/mol, respectively. The viscosity average molecular weigh of the copolymer and the k_p^2/k_t ratio weredctermired to further assess the accelerating effect of CuCl_2 on the copolymerization process. The copolymerization processin the presence of CuCl_2 has a radical complex mechanism.