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Benefit evaluation of the Three-Gorges Reservoir migration by an assessment index model based on analytic hierarchy process 被引量:1
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作者 WANG Jun-hui GAN Lian-jun 《Journal of Chongqing University》 CAS 2007年第2期100-106,共7页
An assessment index model was established to evaulate the benefit of the Three-Gorges Reservoir migration through the analytical hierarchy process. Totally 43 indicators were selected to assess the impact of migration... An assessment index model was established to evaulate the benefit of the Three-Gorges Reservoir migration through the analytical hierarchy process. Totally 43 indicators were selected to assess the impact of migration on the economic, social and ecological environmental aspects of the migration communities, with the data of the indicators of the years 1992, 1998, 2002 which represented the period of premigration, the end of the first phase migration and the end of the second phase migration, respectively. The evaluation matrix is sufficiently consistent, with a consistency ratio CR equal to 0.086 3. The assessment turned out a benefit value for the economic subsystem in the year 2004 larger than triple the value in the year 1992, indicating a remarkable economic growth in the Reservoir area. The constantly increasing value for the social subsystem reflects the stable social situations. There is a slight decline in the assessment outcome of the ecological subsystem for the year 1998, which implies enviromental conservation was given insufficient importance during that period. On the whole, the implementation of the migration project is favorable to the Reservoir region, as confirmed by the stably increasing overall evaluation value from 42.22% in 1992 to 68.81% in 2002. However, there is still much room to improve from the status quo to the target criteria. 展开更多
关键词 Three-Gorges Reservoir migration benefit index system comprehensive assessment
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Colombian Migration and the Body Mass Index: The Relationship between Migration and Weight Gain among Colombian Migrants
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作者 Michael B. Aguilera 《Food and Nutrition Sciences》 2023年第11期1078-1093,共16页
The Latin American Migration Project-Colombia is used to study the Body Mass Index (BMI) of Colombian migrants to determine whether their BMI score increased the longer they were abroad. The study contributes to the l... The Latin American Migration Project-Colombia is used to study the Body Mass Index (BMI) of Colombian migrants to determine whether their BMI score increased the longer they were abroad. The study contributes to the literature on BMI by studying Colombian migrants, an understudied migrant group. Duration of trip is used as a measure of acculturation. The study also evaluates the claim that trip duration is a measure of acculturation using data specific to migrants, which shows that trip duration is an adequate proxy measure of acculturation. The study includes current migrants, returned migrants and non-migrants. The study accounts for the selectivity of migration by comparing migrants to non-migrants, as some studies highlight the health selectivity of migration. The study uses multinomial regression to test whether the probability of being overweight and/or obese is associated with spending more time abroad. Consistent with studies conducted within the receiving countries, the study finds that increased duration of trip is positively and significantly associated with the probability of being overweight and obese. Furthermore, the study also shows that among return migrants there is a negative relationship between time they had remained in Colombia and probability of being obese. The findings show that migrants put on weight while abroad and lose that weight the longer they remain in Colombia. The findings show that place has an indelible impact on health through migrant’s weight. 展开更多
关键词 Body mass index migration Colombia ACCULTURATION
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Soxllb regulates the migration and fate determination of Müller glia-derived progenitors during retina regeneration in zebrafish 被引量:4
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作者 Kaida Song Zihao Lin +5 位作者 Lining Cao Bowen Lu Yuxi Chen Shuqiang Zhang Jianfeng Lu Hui Xu 《Neural Regeneration Research》 SCIE CAS CSCD 2023年第2期445-450,共6页
The transcription factor Sox11 plays important roles in retinal neurogenesis during vertebrate eye development.However,its function in retina regeneration remains elusive.Here we report that Sox11 b,a zebrafish Sox11 ... The transcription factor Sox11 plays important roles in retinal neurogenesis during vertebrate eye development.However,its function in retina regeneration remains elusive.Here we report that Sox11 b,a zebrafish Sox11 homolog,regulates the migration and fate determination of Müller glia-derived progenitors(MGPCs)in an adult zebrafish model of mechanical retinal injury.Following a stab injury,the expression of Sox11 b was induced in proliferating MGPCs in the retina.Sox11 b knockdown did not affect MGPC formation at 4 days post-injury,although the nuclear morphology and subsequent radial migration of MGPCs were alte red.At 7 days post-injury,Sox11 b knockdown res ulted in an increased proportion of MGPCs in the inner retina and a decreased propo rtion of MGPCs in the outer nuclear layer,compared with controls.Furthermore,Sox11 b knockdown led to reduced photoreceptor regeneration,while it increased the numbe rs of newborn amacrines and retinal ganglion cells.Finally,quantitative polymerase chain reaction analysis revealed that Sox11 b regulated the expression of Notch signaling components in the retina,and Notch inhibition partially recapitulated the Sox11 b knockdown phenotype,indicating that Notch signaling functions downstream of Sox11 b.Our findings imply that Sox11 b plays key roles in MGPC migration and fate determination during retina regeneration in zebrafish,which may have critical im plications for future explorations of retinal repair in mammals. 展开更多
关键词 cell migration fate determination müllerglia müller glia-derived progenitor Notch signaling photoreceptor retina regeneration Sox11 transcription factor ZEBRAFISH
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A new monitoring index for ecological vulnerability and its application in the Yellow River Basin,China from 2000 to 2022
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作者 GUO Bing XU Mei +1 位作者 ZHANG Rui LUO Wei 《Journal of Arid Land》 SCIE CSCD 2024年第9期1163-1182,共20页
The ecological environment of the Yellow River Basin has become more fragile under the combined action of natural and manmade activities.However,the change mechanisms of ecological vulnerability in different sub-regio... The ecological environment of the Yellow River Basin has become more fragile under the combined action of natural and manmade activities.However,the change mechanisms of ecological vulnerability in different sub-regions and periods vary,and the reasons for this variability are yet to be explained.Thus,in this study,we proposed a new remote sensing ecological vulnerability index by considering moisture,heat,greenness,dryness,land degradation,and social economy indicators and then analyzed and disclosed the spatial and temporal change patterns of ecological vulnerability of the Yellow River Basin,China from 2000 to 2022 and its driving mechanisms.The results showed that the newly proposed remote sensing ecological vulnerability index had a high accuracy,at 86.36%,which indicated a higher applicability in the Yellow River Basin.From 2000 to 2022,the average remote sensing ecological vulnerability index of the Yellow River Basin was 1.03,denoting moderate vulnerability level.The intensive vulnerability area was the most widely distributed,which was mostly located in the northern part of Shaanxi Province and the eastern part of Shanxi Province.From 2000 to 2022,the ecological vulnerability in the Yellow showed an overall stable trend,while that of the central and eastern regions showed an obvious trend of improvement.The gravity center of ecological vulnerability migrated southwest,indicating that the aggravation of ecological vulnerability in the southwestern regions was more severe than in the northeastern regions of the basin.The dominant single factor of changes in ecological vulnerability shifted from normalized difference vegetation index(NDVI)to temperature from 2000 to 2022,and the interaction factors shifted from temperature∩NDVI to temperature∩precipitation,which indicated that the global climate change exerted a more significant impact on regional ecosystems.The above results could provide decision support for the ecological protection and restoration of the Yellow River Basin. 展开更多
关键词 ecological vulnerability spatio-temporal pattern gravity center migration trajectory interaction factors geodetector green index Q-VALUE
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Simulation of dilatancy-controlled gas migration processes in saturated bentonite using a coupled multiphase flow and elastoplastic H2 M model
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作者 Eike Radeisen Hua Shao +3 位作者 Jürgen Hesser Olaf Kolditz Wenjie Xu Wenqing Wang 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2023年第4期803-813,共11页
Dilatancy-controlled gas flow in preferential pathways plays a key role in the safety analysis of radioactive waste repositories.This is particularly the case for bentonite,an often-preferred barrier material.Gas flow... Dilatancy-controlled gas flow in preferential pathways plays a key role in the safety analysis of radioactive waste repositories.This is particularly the case for bentonite,an often-preferred barrier material.Gas flow in preferential pathways is characterized by localization and spontaneous behavior,which is challenging to simulate in numerical models due to strong hydro-mechanical coupling.To analyze a laboratory experiment in the framework of the DECOVALEX-2023 project,this study introduced a new approach of combining continuous modelling methods with spatial material properties derived from material heterogeneities and experimental observations.The proposed model utilized hydro-mechanical spatial distributions,namely Young’s modulus and gas entry pressure,and elastoplasticity combined with a linear swelling model.A conceptual strain-dependent permeability approach simulated dilatancycontrolled gas flow based on hydro-mechanical coupling.To test the effectiveness of the presented approach,a gas injection test in a compacted,saturated bentonite sample was simulated using the opensource code OpenGeoSys 5.8 and compared with experimental observations.The presented methodology is capable of simulating localized gas flow in preferential pathways.The spatial distributions of Young’s modulus and gas entry pressure affect the swelling pressure,relative permeability and,in combination with the strain-dependent permeability model,also the intrinsic permeability. 展开更多
关键词 H^(2)m coupling Gas migration Dilatancy-controlled flow Continuous approach Geomaterial heterogeneity OPENGEOSYS
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The effects and mechanisms of cytoplasmic Macrophage colony-stimulating factor (M-CSF) on the proliferation,migration and invasion of HeLa cells
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作者 ZHANG Meng-xia2,WU Hai-yan1,TU Jian1,ZHANG Xiao-hong2,LE Xiao-yong1,TANG Sheng-song1,2(1.Institute of Pharmacy and Pharmacology,University of South China,Hengyang 421001,China 2.Center for Life Sciences,University of South China,Hengyang 421001,China) 《沈阳药科大学学报》 CAS CSCD 北大核心 2008年第S1期86-87,共2页
Objective To explore the effects and mechanisms of cytoplasmic M-CSF on the proliferation,migration and invasion of HeLa cells.Methods Both pCMV/cyto/myc vector and pCMV/cyto/myc-M-CSF vector was transfected into HeLa... Objective To explore the effects and mechanisms of cytoplasmic M-CSF on the proliferation,migration and invasion of HeLa cells.Methods Both pCMV/cyto/myc vector and pCMV/cyto/myc-M-CSF vector was transfected into HeLa-cell by transfectaimine.After screening by G418,the positive clones were amplified and confirmed by RT-PCR,Western blot and immunocytochemistry.The effect of cytoplasmic M-CSF on the proliferation of HeLa cells were analyzed by cell conuting and antisense oligonucleotides.The migration and invasion of cell was measured by in vitro Transwell assay and Matrigel-coated polycarbonate filters.The expression of cyclinE,cyclinD1/2/3,CDK2/4/6,Rac1,and matrix metalloproteinase 2 and 9(MMP2/9)were assayed by semiquantitative RT-PCR.And expression of both α-tubulin and cdc42 were displayed by immunofluorescence.The activity of MMP2 was detected by gelatin zymography.Results Results A cell line(referred as to HeLa-M cell)that highly expresses cytoplasmic M-CSF was successfully established in the test.Our result indicated that HeLa-M cell had a larger volume,faster growth rate and shorter doubling time than either pCMV/cyto/myc transfected HeLa cells(referred as to HeLa-C cell)or untransfected HeLa cells(referred as to HeLa cell).M-CSF-specific antisense oligonucleoside significantly inhibited HeLa-M cell proliferation and had little effect on either HeLa-C cell or HeLa-C cell growth.Cytoplasmic M-CSF up-regulated both the expression of cyclinE,cyclinD1 and cyclinD3,CDK2,CDK 4 and CDK6,a Rho GTPase ralative protein(Rac1),cdc42 and MMP2,but had little effect on expression of MMP9 and cyclin D2.Furthermore,cytoplasmic M-CSF induced the rearrangement of the α-tubulin in HeLa cells and significantly promoted the migration and invasion of HeLa cells in vitro.Conclusions Cytoplasmic M-CSFs up-regulate the expression of cyclinE,cyclinD1 and cyclinD3,CDK2,CDK 4 and CDK6 and induces the proliferation of HeLa cells.Cytoplasmic M-CSFs up-regulate the expression of Rac1 and cdc42 and cause the rearrangement of the α-tubulin in HeLa cells.Furthermore Cytoplasmic M-CSFs increase both the expression and activity of MMP2 and promote the migration and invasion of HeLa cell in vitro.But cytoplasmic M-CSFs have little effect on expression of cyclin D2 and MMP9. 展开更多
关键词 m-CSF HELA cell line CYTOSKELETON migration INVASION
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Ray equation migration of wide-angle reflections in Dabie orogenic zone
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作者 郑需要 王椿镛 +1 位作者 赖晓玲 张先康 《Acta Seismologica Sinica(English Edition)》 CSCD 1998年第2期63-72,共10页
ay equation migration of wide-angle reflections in 2-D medium is one kind of Kirchhoff prestack depth migration method. Based on ray theory, this method can be used extensively in 2-D inhomogeneous medium, and shows i... ay equation migration of wide-angle reflections in 2-D medium is one kind of Kirchhoff prestack depth migration method. Based on ray theory, this method can be used extensively in 2-D inhomogeneous medium, and shows its advantage in wide-angle reflection study. After calculating ray fields, we can get the wave fields of sources and receivers by interpolation, and the intensity (or amplitude) AP corresponding to the depth point P at travel-time tP=tSP+tPR can be found in seismograms. Ray equation migration is completed by transforming AP according to the specific relation, migrating it to the depth point, then calculating the ray fields of lots of sources and receivers in the same way and finally stacking the outcomes. Numerical calculation has yielded satisfactory results. Data processing of the Zhuangmu-Yuexi-Huangmei-Zhanggongdu profile passing through the Dabie orogenic zone provides a structural form of M-discontinuity along the profile. The result shows that the high pressure metamorphic rock zone of South Dabie rock mass is related to the uplifting of M-discontinuity here. 'Mountain root' exists under North Dabie rock mass, which conforms with gravity isostasy theory. The Xiaotian-Mozitan fault is a suture zone as a result of the collision of North China plate with Yangtze plate, and extends through M-discontinuity. The abyssal fault near Liu'an is the extended eastern section of the Luonan-Minggang fault, which is also confirmed here. 展开更多
关键词 ray equation migration seismic profile m-discontinuity abyssal fault Dabie orogenic zone
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M*(k)-index构造算法的改进
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作者 任家东 马瑞 《计算机工程》 CAS CSCD 北大核心 2008年第19期58-60,共3页
一些基于图结构的索引技术通过缩小查询范围提高对XML数据的查询速度,但存在分隔不相关节点的问题。该文改进M*(k)-index的构造算法,用单一的M**(k)-index结构取代原算法的序列结构,以避免存储序列成员中的节点与边及序列成员之间的链接... 一些基于图结构的索引技术通过缩小查询范围提高对XML数据的查询速度,但存在分隔不相关节点的问题。该文改进M*(k)-index的构造算法,用单一的M**(k)-index结构取代原算法的序列结构,以避免存储序列成员中的节点与边及序列成员之间的链接,提高其存储性能和查询效率。实验结果表明,改进后的结构具有良好性能。 展开更多
关键词 XmL数据 索引结构 m*(k) -index结构
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Peterson图和图D_(m,n)的边PI指数
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作者 张丽 张辉 红霞 《宁夏师范学院学报》 2024年第4期5-15,共11页
利用分析法和分类讨论法,给出Peterson图和D_(m,n)图的边PI指数计算公式,丰富了图的PI指数理论.
关键词 边PI指数 Peterson图 图Dm N
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A comparison of the applicability of the Shannon-Wiener index,AMBI and M-AMBI indices for assessing benthic habitat health in the Huanghe(Yellow River) Estuary and adjacent areas 被引量:5
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作者 LUO Xianxiang SUN Kaijing +2 位作者 YANG Jianqiang SONG Wenpeng CUI Wenlin 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2016年第6期50-58,共9页
From a dataset of macrobenthos obtained from 18 cruises from 2004 to 2013 in the Huanghe(Yellow River)Estuary and its adjacent areas,the composition and characteristics of macrobenthos were analyzed,and the applicab... From a dataset of macrobenthos obtained from 18 cruises from 2004 to 2013 in the Huanghe(Yellow River)Estuary and its adjacent areas,the composition and characteristics of macrobenthos were analyzed,and the applicability of the Shannon-Wiener Index(H′),AZTI's Marine Biotic Index(AMBI) and multivariate AMBI(MAMBI) for assessing benthic habitat quality was compared.The results showed a total of 203 macrobenthos in the study area.The macrobenthos were dominated by polychaetes,followed by mollusks and crustaceans.The macrobenthic ecological groups were dominated by EGI,EGII and EGIII,which respectively accounted for 31.5%,36.0% and 21.2% of the total.There were significant differences between the evaluation results of the three indices.The ecological quality status(EQS) levels given by the AMBI were greater than those given by the H′ and M-AMBI.The AMBI could not reflect the differences between 11 sites but the H′ and M-AMBI could do.Moreover,the three indices responded well to the variations in salinity(S) and dissolved oxygen(DO) in the waters.The H′ and MAMBI also responded sensitively to the differences in physical parameters,such as water depth and sediment texture.The correlation between M-AMBI and environmental pressure gradient data was the strongest.The MAMBI could effectively distinguish degraded conditions from undegraded but the H′ and AMBI could not.Therefore,the M-AMBI reflected benthic habitat health well in the study areas.However,the objectivity of evaluation results of M-AMBI needs further verification by physical,chemical and biological methods.The thresholds also need further discussion. 展开更多
关键词 mACROBENTHOS ecological quality status Huanghe Estuary Shannon-Wiener index AmBI m-AmBI
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基于AMBI和M-AMBI法的桑沟湾底栖生态环境质量评价
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作者 李文豪 于晓清 +4 位作者 蒋增杰 杜美荣 贾彦 何为 高亚平 《中国海洋大学学报(自然科学版)》 CAS CSCD 北大核心 2024年第6期55-67,共13页
养殖环境评价是衡量海水养殖活动是否健康、可持续的重要环节。为掌握北方典型规模化养殖海湾——桑沟湾沉积环境质量状况,于2017年4和7月对桑沟湾全湾海域进行大型底栖动物走航调查取样,分析了大型底栖动物的种类组成、生物量、栖息密... 养殖环境评价是衡量海水养殖活动是否健康、可持续的重要环节。为掌握北方典型规模化养殖海湾——桑沟湾沉积环境质量状况,于2017年4和7月对桑沟湾全湾海域进行大型底栖动物走航调查取样,分析了大型底栖动物的种类组成、生物量、栖息密度及群落结构;运用AMBI(AZTI’s marine biotic index)指数法和M-AMBI(Multivariate-AMBI)指数法,分析了大型底栖动物群落受干扰程度,评价了沉积环境质量状况。研究表明,在两次调查中多毛类均为优势种,其中4月多毛类36种,占总种数63.16%;7月32种,占总种数的60.38%。AMBI法的评估结果表明,调查海域各站位以受到轻度扰动为主,个别站位受到中度扰动和无扰动,干扰程度从小到大依次为海带区<海草区<混养区<贝类区;M-AMBI法的评估结果表明,生态环境质量等级为良或优的站位占60.00%~68.42%,海草区环境质量状况要明显好于养殖区。多营养层次综合养殖模式缓解了桑沟湾近海生态系统的养殖压力,使得桑沟湾受人为干扰较小,海草区环境质量为优,贝类区、混养区和海带区的环境质量处于中等和良之间。 展开更多
关键词 桑沟湾 大型底栖动物 AmBI指数 m-AmBI指数 底栖生态环境质量
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Migrated Exploding Reflectors in Evaluation of Finite Difference Solution for Inhomogeneous Seismic Models
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作者 Maryam Nejati Hosein Hashemi 《Engineering(科研)》 2012年第12期950-957,共8页
Earth is inhomogeneous, which means its elastic characteristics change with depth. The seismic method employs the propagation of waves throughout the earth to locate different structures and stratigraphy. Understandin... Earth is inhomogeneous, which means its elastic characteristics change with depth. The seismic method employs the propagation of waves throughout the earth to locate different structures and stratigraphy. Understanding the wave propagation is an important matter in exploration seismology;therefore modeling of seismic wave is an important tool. To validate the interpreted earth model out of the seismic data, seismic synthetic seismograms should be generated in a process named “seismic forward modeling”. Finite difference method is used as one of the most common numerical modeling techniques. In this paper the accuracy of finite difference method in seismic section modeling is explored on different modeled data set of heterogeneous earth. It is shown that finite difference method completes with migration to reposition the events in their correct location. Two different migration methods are used and various velocities are also tested to determine an appropriate migration velocity. Finally the validly of finite difference modeling is examined using a 2D structural similarity index technique. 展开更多
关键词 Finite DIFFERENCE method SEISmIC modeling migration Exploding REFLECTOR Structural SImILARITY index
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解剖性肝切除术对肝癌患者免疫指标及 MIF、MAGE-1 mRNA、AFP mRNA水平的影响
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作者 施喆 韩艳珍 +3 位作者 李桂芳 李献平 胡景景 安西全 《中国实验诊断学》 2024年第11期1266-1270,共5页
目的 探讨解剖性肝切除术和局部肝切除术对肝癌患者免疫指标和巨噬细胞移动抑制因子(MIF)、黑色素瘤抗原-1信使核糖核酸(MAGE-1 mRNA)、甲胎蛋白信使核糖核酸(AFP mRNA)水平的影响。方法 回顾性分析河北工程大学附属医院2020年1月至2022... 目的 探讨解剖性肝切除术和局部肝切除术对肝癌患者免疫指标和巨噬细胞移动抑制因子(MIF)、黑色素瘤抗原-1信使核糖核酸(MAGE-1 mRNA)、甲胎蛋白信使核糖核酸(AFP mRNA)水平的影响。方法 回顾性分析河北工程大学附属医院2020年1月至2022年10月行肝癌切除术100例患者,观察组50例行解剖性肝切除术,对照组50例行局部肝切除术。对两组患者的手术情况、术前和术后1周的免疫指标,术前和术后1个月的血清MIF、MAGE-1 mRNA、AFP mRNA阳性表达水平及术后1个月内的并发症进行比较。结果 观察组手术时间长于对照组,观察组术中出血量、术中输血量均少于对照组,观察组切缘有效率高于对照组;与术前比较,术后1周两组外周血CD3^(+)、CD4^(+)、CD4^(+)/CD8^(+)、CD19^(+)均降低,但观察组高于对照组;两组外周血CD8^(+)均升高,但观察组低于对照组;两组血清MIF、MAGE-1 mRNA、AFP mRNA阳性表达水平均降低,且观察组低于对照组;术后1个月内观察组并发症总发生率为12.00%,明显低于对照组的28.00%,差异均有统计学意义(P<0.05)。结论 解剖性肝切除术应用于肝癌患者可有效减少术中出血量和输血量,提高切缘有效率,促进免疫功能改善,减轻免疫炎性反应,降低MAGE-1 mRNA、AFP mRNA阳性表达水平,具有较低的并发症发生率。 展开更多
关键词 肝癌 解剖性肝切除术 免疫指标 巨噬细胞移动抑制因子
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Mobile Agent选择移动迁移机制的设计与实现 被引量:8
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作者 蔡洪波 张大方 谢高岗 《计算机工程与科学》 CSCD 2001年第5期54-57,共4页
本文首先分析了当前 Mobile Agent系统面临的问题 ,提出了选择移动迁移机制的概念 ;然后对传统迁移机制和选择移动迁移机制对网络负载的影响进行了定量研究 ;最后 ,给出了一种采用选择移动迁移机制的 Mobile Agent系统模型 。
关键词 mOBILE AGENT 迁移机制 网络负载 计算机网络
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参杖颗粒含药血清对HSC增殖及α-SMA表达的抑制效应 被引量:4
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作者 段妍君 殷妮娜 +4 位作者 高清华 万莹 马维平 张昌文 吕文亮 《世界华人消化杂志》 CAS 北大核心 2014年第10期1396-1401,共6页
目的:研究参杖颗粒对α-平滑肌肌动蛋白(alpha smooth muscle actin,α-SMA)表达的影响,探讨该方影响肝星状细胞(hepatic stellate cell,HSC)迁移和增殖的调节机制.方法:将HSC分别培养于不同浓度的参杖颗粒含药血清中,采用Western blot... 目的:研究参杖颗粒对α-平滑肌肌动蛋白(alpha smooth muscle actin,α-SMA)表达的影响,探讨该方影响肝星状细胞(hepatic stellate cell,HSC)迁移和增殖的调节机制.方法:将HSC分别培养于不同浓度的参杖颗粒含药血清中,采用Western blot测定α-SMA的表达量;RT-PCR检测α-SMA mRNA表达量;流式细胞仪检测不同浓度的含药血清对HSC周期的影响;细胞划痕实验检测不同浓度的含药血清对HSC迁移的影响.结果:Western blot实验结果显示10倍浓度的参杖颗粒含药血清对HSC的α-SMA的表达有明显减少;同时RT-PCR结果显示α-SMA的mRNA水平在10倍浓度血清处理的HSC中最低;细胞周期检测结果显示细胞明显被阻滞于G2期,以10倍浓度组抑制增殖效果最明显;划痕实验显示10倍浓度血清处理的HSC迁移能力明显被抑制.结论:参杖颗粒对HSC的α-SMA的表达有明显抑制作用,并明显阻止HSC的迁移和增殖. 展开更多
关键词 肝星状细胞 Α-平滑肌肌动蛋白 参杖颗粒 增殖 迁移
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阶跃光纤低阶线偏振模的M^2因子分析 被引量:4
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作者 傅玉青 冯国英 +2 位作者 张大勇 陈建国 周寿桓 《光子学报》 EI CAS CSCD 北大核心 2008年第7期1342-1345,共4页
针对阶跃光纤输出低阶线偏振模(Linear Polarization,LP),利用二阶距定束宽,多点拟合法计算了几个低阶LPmn模相干和非相干叠加时的M2因子.结果表明,对同一LPmn模式,光纤的归一化频率参量V减小到截止频率时,M2因子出现峰值;当V远离截止... 针对阶跃光纤输出低阶线偏振模(Linear Polarization,LP),利用二阶距定束宽,多点拟合法计算了几个低阶LPmn模相干和非相干叠加时的M2因子.结果表明,对同一LPmn模式,光纤的归一化频率参量V减小到截止频率时,M2因子出现峰值;当V远离截止频率时M2因子趋于一定值.低阶LPmn模非相干叠加时,叠加后的较高阶模成分越大,合成光束的光束质量越差,光束在一定的条件下可能比基模更接近于理想高斯光束;而相干叠加时,合成后的M2因子可以大于参与叠加的较高阶模的光束质量因子. 展开更多
关键词 m^2因子 线偏振模 阶跃光纤
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100m跑运动员体能指标研究综述 被引量:7
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作者 袁运平 戴名辉 《沈阳体育学院学报》 2004年第2期151-154,共4页
根据运动员体能结构的关系,从体能指标角度对运动员的体能进行系统地研究。结果表明,近些年来国内外对100m跑运动员的研究从整体上讲较为分散零碎,缺乏整体系统性。主要表现在这些研究多从微观入手,过多关注的是体能具体分类指标本身,... 根据运动员体能结构的关系,从体能指标角度对运动员的体能进行系统地研究。结果表明,近些年来国内外对100m跑运动员的研究从整体上讲较为分散零碎,缺乏整体系统性。主要表现在这些研究多从微观入手,过多关注的是体能具体分类指标本身,从系统的观点对100m跑运动员体能水平的综合整体研究还比较薄弱。 展开更多
关键词 100m 运动员 体能指标 综述 体能水平 身体形态 身体机能 运动素质
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基于MCI的厦门湾大型底栖动物群落健康状况评价 被引量:5
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作者 朱延忠 周娟 +3 位作者 林岿璇 刘静 蔡文倩 刘录三 《广西科学》 CAS 2015年第5期549-557,共9页
[目的]对厦门湾的底栖动物群落健康状况进行调查分析,初步构建合适的评价方法,并据此判断厦门湾的底栖生态质量状况。[方法]以2011年3月、6月调查数据为基础,采用Shannon-Wiener生物多样性指数、Margalef丰富度指数以及M-AMBI(Multivari... [目的]对厦门湾的底栖动物群落健康状况进行调查分析,初步构建合适的评价方法,并据此判断厦门湾的底栖生态质量状况。[方法]以2011年3月、6月调查数据为基础,采用Shannon-Wiener生物多样性指数、Margalef丰富度指数以及M-AMBI(Multivariate-AZTI’s Marine Biotic Index)作为构建大型底栖动物群落指数(macrozoobenthos community index,MCI)的指标,在等权重加和的基础上获得MCI值。[结果]3月份厦门湾大型底栖动物群落质量差于6月份,且以同安湾的质量最差,东部和西部海域的则最好;九龙江口河口区的群落质量状况呈现明显的空间梯度,沿河口向外、向北部逐渐变好。[结论]厦门湾底栖动物群落之间的时空差异与多种环境因素的联合作用有关,而MCI能够较为敏感地响应这种时空变化,适用于评价厦门湾大型底栖动物群落质量状况。 展开更多
关键词 大型底栖动物群落 Shannon-Wiener 生物多样性指数 margalef丰富度指数 m-AmBI mCI 厦门湾
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全方位M-型超声评价高血压病患者左心室Tei指数及其相关参数 被引量:3
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作者 李楠 靳忠民 +3 位作者 任卫东 唐力 陈昕 马春燕 《中国医学影像技术》 CSCD 北大核心 2009年第4期605-608,共4页
目的评估采用全方位M-型(FAM)超声技术检测高血压病患者左心室Tei指数、等容收缩指数(ICT/ET)、等容舒张指数(IRT/ET)等参数改变的效果。方法选取原发性高血压病患者80例,依据左心室心肌重量指数(LVMI)分为2组:左心室心肌肥厚组(A组,LV... 目的评估采用全方位M-型(FAM)超声技术检测高血压病患者左心室Tei指数、等容收缩指数(ICT/ET)、等容舒张指数(IRT/ET)等参数改变的效果。方法选取原发性高血压病患者80例,依据左心室心肌重量指数(LVMI)分为2组:左心室心肌肥厚组(A组,LVMI:男性≥120g/m2,女性≥115g/m2)21例;左心室心肌无肥厚组(B组,LVMI:男性<120g/m2,女性<115g/m2)59例。60名健康人作为对照组(C组)。先通过常规超声检查对受检者进行各基础参数指标的测量,然后采用FAM技术测量左心室Tei指数及ICT/ET、IRT/ET等各相关参数,分析评价各指标临床意义及相关性。结果B、C两组ICT/ET的差异无统计学意义。A、B两组的Tei指数及ICT/ET、IRT/ET显著大于C组(P<0.01);Tei指数及其相关参数与部分传统超声评价指标相关性良好。结论应用Tei指数结合ICT/ET、IRT/ET等相关参数可更全面地综合评价高血压病患者的左心室整体功能表现,FAM技术为Tei指数及其相关参数的测量与评价提供了新的检测手段。 展开更多
关键词 超声心动描记术 全方位m-型 高血压病 左心室功能 TEI指数
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应用E指数、M指数定量评价兔早期急性肺栓塞 被引量:1
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作者 丛志斌 任卫东 +2 位作者 马春燕 杨玉洁 姜镔 《中国介入影像与治疗学》 CSCD 2010年第1期50-53,共4页
目的探讨兔早期急性肺栓塞(APE)后肺动脉高压(PHT)状态下E指数、M指数的变化及意义。方法建立有PHT的兔APE模型,常规超声心动图及组织多普勒成像(TDI)检测栓塞前、后的二尖瓣舒张早期速度E峰(EM)、舒张晚期速度A峰(AM)等多项参数,计算E... 目的探讨兔早期急性肺栓塞(APE)后肺动脉高压(PHT)状态下E指数、M指数的变化及意义。方法建立有PHT的兔APE模型,常规超声心动图及组织多普勒成像(TDI)检测栓塞前、后的二尖瓣舒张早期速度E峰(EM)、舒张晚期速度A峰(AM)等多项参数,计算E指数、M指数,并比较栓塞前后的变化。结果成功建立兔APE模型23只,3只兔因房颤未纳入研究。APE后肺动脉压力明显增高,EM明显减低,右心室心肌做功指数较左心室心肌做功指数增大明显。E指数明显减低,M指数明显增大。结论APE后E指数及M指数的改变可能为定量评价早期APE提供新的参考依据。 展开更多
关键词 肺栓塞 心肌做功指数 E指数 m指数
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