Clinical Study on the Effectiveness of Xian Fang Huo Ming Yin for Treating Cutaneous Infections and Promoting Wound Healing in Patients with Perianal Abscess

Objective:To explore the effect of the Xian Fang Huo Ming Yin(XFHM)for treating cutaneous infections and promoting wound healing in patients with perianal abscesses.Methods:Sixty-one patients with perianal abscesses who were admitted to our hospital(Xinghua City People’s Hospital)from May 2022 to May 2023 were selected and randomly divided into two groups,a control group(30 cases)and a study group(31 cases).Both groups received surgical treatment.The control group received conventional treatment and warm water fumigation,sitz bath,and surgical dressing change after surgery,while the research group received XFHM based on the control group.XFHM was taken orally and replaced with warm water for fumigation and sitz bathing.Both groups received treatment for 4 weeks but discontinued sitz bathing after 2 weeks.Various clinical indicators between the two groups were compared.Results:The total clinical effective rate and wound recovery rate of the study group were higher than that of the control group.There were differences in the wound pain scores,surrounding tissue edema,and wound secretions at different time points.Both groups experienced wound pain.The scores of wound pain,surrounding tissue edema,and wound secretions of the study group were lower than those of the control group,7 and 14 days after surgery.The serum interleukin 6(IL-6),tumor necrosis factor-alpha(TNF-α)levels,and pH values of the study group were lower than those of the control group 10 days after surgery(P<0.05).Conclusion:The application of XFHM for treating cutaneous infections and promoting wound healing in patients with perianal abscesses improved the treatment outcome,alleviated clinical symptoms,and promoted healing.

Review of Dietary Therapy Development in Ming and Qing Dynasties

In the Ming and Qing Dynasties,with the development of politics,economy and culture,the development of health maintenance of traditional Chinese medicine entered a heyday.Food therapy is an important part of the health theory of traditional Chinese medicine.In the 5,000 years of Chinese civilization,you can see the record of food therapy everywhere.It can be said that food therapy of traditional Chinese medicine develops together with traditional Chinese medicine.As a treasure in the treasure-house of Chinese medicine,food therapy has a long history and rich practice.Based on the current research,further research on relevant theories remains to be carried out.Focusing on the historical period of Ming and Qing dynasties,this paper takes the works related to food,nutrition and therapy(including general works and monographs on diet),the health thoughts and practice characteristics of representative health practitioners as the research perspective,and sorts out the above research contents in the past 20 years,analyzes the research overview and trend.It is found that in the study of food nourishing in Ming and Qing dynasties,there are few studies on the contents of diet nourishing in the general works.This suggests that when we study the development of diet nourishing in Ming and Qing Dynasties,we should not only study the monograph of diet nourishing and the thoughts of doctors,but also pay attention to the diet nourishing thought reflected in the general works.The study of diet monographs in Ming Dynasty mainly focused on the textual research of wild plants,and the study of diet monographs in Qing Dynasty mainly focused on the application.The study on the health care thought of doctors in Ming and Qing Dynasties mainly focused on the views of food nourishing and personal health care.These studies are summarized in order to provide reference for further theoretical research and provide reference for contemporary research on food nourishing diet.

Combining sum-difference and auxiliary beams for adaptive monopulse in jamming

Only in the presence of sidelobe jamming （SLJ）, can the conventional adaptive monopulse technique null the jamming effectively and maintain the monopulse angle estimation accuracy simultaneously. While mainlobe jamming （MLJ） exists, the mainlobe of adaptive pattern will subject to serious distortion, which results in a failure of detecting and tracking targets by monopulse technique. Therefore, a monopulse angle estimation algorithm based on combining sum-difference beam and auxiliary beam is presented. This algorithm utilizes both high gain difference beams and high gain auxiliary beams for cancelling the mainlobe jammer and multiple sidelobe jammers （SLJs） while keeping an adap- tive monopulse ratio. Theoretical analysis and simulation results indicate that the serious invalidation of monopulse technique in MLJ and SLJs scenarios is resolved well, which improves the monopulse angle accuracy greatly. Furthermore, the proposed algorithm is of simple implementation and low computational complexity.

Ming河渡槽结构动力分析

河北省境内的Ming河渡槽是南水北调工程中重要的输水建筑物。它的最大特点是输水量巨大、体型庞大。而以往对大型渡槽的研究却很少。因此，对三槽厢联的Ming河渡槽进行研究具有重要意义。本文利用ANSYS软件对该渡槽进行结构动力分析，为工程实践提供理论依据和指导建议。

The Influence of Aesthetic Ideology of TAO Yuan-ming on Classical Gardens in South China

Based on the contents and temperament of pastoral poetries written by TAO Yuan-ming,by centering on respecting the nature,indifference and optimism,and plainness and authenticity,the paper had analyzed aesthetic ideologies contained in his poetries.On this basis,it had discussed the influence of aesthetic ideology of TAO Yuan-ming on the style of classical gardens in South China,which were quiet and natural,elegant and fresh,simple and plain,and far-reaching in artistic conception.By combining with cases,it pointed out that the poetic prose had been directly quoted as the names of gardens or scenic spots of classical gardens in South China,and showed that the aesthetic ideology of TAO Yuan-ming had set up a successful ideal model for cultural landscapes,producing far-reaching influence on the aesthetic state of mind of gardeners or owners of gardens,further instilling humanistic spirit into classical gardens in South China.

Study on the Factors of Kunming Temple Garden in the Period of Ming and Qing Dynasties

Being based on preliminary study of Kunming famous temples during the Ming and Qing dynasties,field investigation was carried out about the framework of landscape,layout of waters,characteristic of structure and plant furnishing in Tanhua temple,Black Dragon Pool,Masijid of Shuncheng,Haiyuan temple and Golden Shrine which are famous temple garden in Kunming. A simple interpretation was drawn of artistic characteristics on temple garden in Kunming during the Ming and Qing dynasties via analytical investigation on many factors which influenced the development of garden of Dynasties of Ming and Qing. Then we have reviewed the elemental traits of temple garden built at that time,put forward some constructive suggestions on how to protect and develop those temple garden now still exist in Kunming.

Rectifying Names Is a Must——Xun Zi's Linguistic Ideas in Zhengming

In China, Warring States Period was imbued with chaos of wars and the whole society was in a state of ferment. The disordered phase in ideological area, as the most direct reflection of the change, was characterized by that all the old ethical standard had been badly weaken, even failed to explain the moral facts. In terms of common people, they were confused and puzzled by the questions as "what is language?" and "what is the standard of speaking and behavior?" Some ancient scholars pinned these problems upon the reversal of "ming" (名) and "shi" (实). As a result, to rectify names and to clarify the name of ethics became a must for reconstructing the old proprieties and system. Among those scholars and thinkers, Xun Zi firstly proposed Zhengming to state the relationship between a name and the thing it represents in a systematical way. This essay only sheds light upon the reason of rectifying names: to distinguish the rank and differentiate the similarities and differences("明贵贱,辨同异")which is the must of "rectifying names".

Dan Huang Ming Mu Recipe Suppresses the Progression of Streptozotocin-induced Diabetic Retinopathy After Retinal Laser Photocoagulation in Brown Norway Rats via Down-regulating Vascular Endothelial Growth Factor and Up-regulating Pigment Epithelium-derived

Objective To analyze the effects of Dan Huang Ming Mu Recipe(DHMMR)(a pharmaceutical preparation from herbs and having the function of replenishing vital essence,removing heat,promoting blood circulation and excreting pathogenic water) on diabetic retinopathy(DR) after retinal laser photocoagulation through regulating the expression of vascular endothelial growth factor(VEGF) and pigment epithelium-derived factor(PEDF).Methods Forty male Brown Norway(BN) rats were randomly divided into blank group(group A,10 BN rats) and model group(30 BN rats).DR models were induced by 40 mg/kg streptozotocin(STZ) and the body weight and blood glucose of rats were monitored.After 12-week injection,fluorescein fundus angiography(FFA) and histopathological examination were detected to confirm the successful establishment of DR models.Subsequently,the right eyes of model group rats were conducted retinal laser photocoagulation with the left eyes having no retinal laser photocoagulation and rats of the model group were randomly divided into group B(the model control group),group C(the positive control group),and group D(the DHMMR group),with 10 rats in each group.Rats of the group A and the group B were given vehicle,and the group C were given calcium dobesilate suspension by gavage,and the group D were given DHMMR by gavage.After 4-week gavage,FFA was carried out to observe the fundus microvascular change.Then,the rats were sacrificed to do histopathological examinations and the serum levels of P-selectin,cAMP,cGMP,and the relative expression of the protein of VEGF and PEDF in retina were detected.Results After 12-week STZ injection,the blood glucose of the model group were pronouncedly higher than the blank group(P < 0.01).Fundus micro-hemangioma changes were observed in the rats of the model group through FFA,and the rats of the blank group did not see any changes.The pictures of HE staining showed that the retinal structure of the model group was more disordered than the blank group.After 4-week gavage,treatments with DHMMR showed dramatic reduction of serum levels of Pselectin,cAMP and cGMP compared with the group B(P < 0.01).FFA and histopathological examinations of DHMMR-treated rats revealed significantly suppression of retinal edema,fundus microvascular destruction and retinal destruction distinguishing from the group B.And the relative expression of VEGF protein of the group D and the group A was markedly lower than that of the group B(P < 0.01).The relative expression of PEDF protein of the group D and the group A was dramatically higher than that of the group B to the contrary(P < 0.01).Conclusions DHMMR demonstrates pronounced suppressive effects on the progression of DR after retinal laser photocoagulation,through down-regulating VEGF and upregulating PEDF.

The Introduction of European Fortification in the Late Ming Period

In the late Ming period,Xu Guangqi and other Catholic literati were actively involved with military affairs because of the invasion of the Manchu forces and the threat of uprisings.The story of how they imported European cannons and gunners from Macao is now quite famous.However,the introduction of European fortifications,mainly the trace Italienne,in the same period is still relatively unknown.Xu Guangqi and his student Sun Yuanhua exerted considerable efforts in advocating European-style bastions.Xu not only received help from Jesuits,but also support from some Fujianese who were familiar with Intramuros,the Spanish walled city of Manila.In addition to Xu and Sun,Han Lin and Han Yun(also Xu’s students)prepared a Chinese treatise on European fortification architecture based on Italian sources and tried to put the knowledge into practice.Another relevant figure is Ma Weicheng,who allegedly directed the building of 32 angled bastions in three cities around 1640.Although a few recorded writings and practices of constructing European-style fortification appeared in the first half of the seventeenth century,soon afterwards the art of trace Italienne met its end prematurely in China.To a great extent,the swift collapse of the Ming dynasty eliminated the possibility of spreading the new defense technology.Throughout the eighteenth century,the Qing dynasty enjoyed long-term peace,and the warfare at the frontiers brought few threats to the city walls.There was thus little urgency to develop innovative defensive works and European fortification sunk into oblivion until the mid-nineteenth century.

Effects of Shuang Dan Ming Mu Capsule on Expression of VEGF-a, VEGF-b, VEGF-c and the VEGF receptor, Flk-1, in Diabetic Retinopathy Rats

Objective The effects of Shuang Dan Ming Mu capsule on expression of VEGF-a,VEGF-b,VEGF-c and the VEGF receptor,Flk-1,were examined in a diabetic retinopathy rats model.Methods Forty Sprague-Dawley(SD)rats were randomized into Groups A(blank),B(model),C(Shuang Dan Ming Mu)and D(positive control)group,with each group containing10rats and20eyes.Rats from groups B,C and D were administered one dose of50mg/kg streptozotocin(STZ)by tail vein injection to establish a diabetic rat model.One week after model preparation,medication was continuously administered by gavage.After gavage for8weeks,the animals were sacrificed and retinal expression of VEGF-a,VEGF-b,VEGF-c and Flk-1was quantified by immunohistochemical analysis.Results At week8of drug administration after model preparation,the average protein expression grayscale values for VEGF-a,VEGF-b,VEGF-c and Flk-1in the rats model,Shuang Dan Ming Mu and positive control groups were all lower than those in the normal group,while the mean optical density values were higher than those in the normal group.When the model group was compared to the normal group,the difference was extremely significant(P<0.01).The mean grayscale values of VEGF-a,VEGF-b,VEGF-c and Flk-1in the Shuang Dan Ming Mu and positive control groups were all higher than those in the model group,while the mean optical density values were lower than those in the model group(P<0.05or0.01).Conclusion Shuang Dan Ming Mu capsule can significantly decrease the expression of VEGF-a,VEGF-b,VEGF-c and Flk-1in the retinas of diabetic model rats and exhibit some protective effects in their retinas.

基于PHP+Ming的业务监控显示平台设计

由于气象业务具有种类较多的特点,如果只依靠人工监测对业务运行质量进行判断,那么工作量将会大大增加。因此,为了对气象业务实现实时监控及评价,设计出基于PHP+Ming的业务监控显示平台便显得极为重要。本课题笔者重点对基于PHP+Ming的业务监控显示平台设计进行了探究,希望以此为有关气象业务工作的完善提供一些具有价值性的参考依据。

Xiao-Xu-Ming decoction extract regulates differentially expressed proteins in the hippocampus after chronic cerebral hypoperfusion

Xiao-Xu-Ming decoction has been widely used to treat stroke and sequelae of stroke. We have previously shown that the active fractions of Xiao-Xu-Ming decoction attenuate cerebral ischemic injury. However, the global protein profile and signaling conduction pathways regulated by Xiao-Xu-Ming decoction are still unclear. This study established a two-vessel occlusion rat model by bilateral common carotid artery occlusion. Rats were intragastrically administered 50 or 150 mg/kg Xiao-Xu-Ming decoction for 4 consecutive weeks. Learning and memory abilities were measured with Morris water maze. Motor ability was detected with prehensile test. Coordination ability was examined using the inclined screen test. Neuronal plasticity was observed by immunofluorescent staining. Differentially expressed proteins of rat hippocampus were analyzed by label-free quantitative proteomics. Real time-polymerase chain reaction and western blot assay were used to identify the changes in proteins. Results showed that Xiao-Xu-Ming decoction dramatically alleviated learning and memory deficits, and motor and coordination dysfunction, and increased the expression of microtubule-associated protein 2. Xiao-Xu-Ming decoction extract remarkably decreased 13 upregulated proteins and increased 39 downregulated proteins. The regulated proteins were mainly involved in oxidation reduction process, intracellular signaling cascade process, and protein catabolic process. The signaling pathways were mainly involved in ubiquitin mediated proteolysis and the phosphatidylinositol signaling system. Furthermore, there was an interaction among Rab2 a, Ptpn1, Ppm1 e, Cdk18, Gorasp2, Eps15, Capza2, Syngap1 and Mt-nd1. Protein analyses confirmed the changes in expression of MTND1. The current findings provide new insights into the molecular mechanisms of Xiao-Xu-Ming decoction extract's effects on chronic cerebral hypoperfusion.

The Leisure Style of Men of Letters in the Late Ming Dynasty and Its Social Influence

This paper explored the background of the leisure boom among the literati in the late Ming Dynasty from the aspects of politics, economy, ideology and social environment, and elaborated the leisure styles of the literati in terms of enjoying a sightseeing tour, sampling wine and tea, appreciating and collecting calligraphy and painting works, favoring theatergoing, indulging in dallying with prostitutes, practicing meditation, and building gardens, and analyzed the influence of their leisure styles on the painting and calligraphy art, drama, literary creation, garden construction and other aspects of the society at that time. It is hoped that this paper can provide a deep understanding of social politics, economy, ideology and culture in the late Ming Dynasty and a reference for the development of the current leisure tourism.

Image Style of the Tianping Mountain Landscape in the Ming Dynasty

Starting from the Tianping Mountain theme painting in Suzhou in the Ming Dynasty, we explore how did the painters and literati in this period shape the image of the Tianping Mountain through their works, thereby reflecting their understanding on many landscapes on the Tianping Mountain. By exploring a series of paintings and poems, we try to analyze the characteristics and cultural connotation of landscape paintings of the Tianping Mountain in the Ming Dynasty, which is conducive to improving position of the Tianping Mountain natural and humanistic landscape in Suzhou.

Overview of the plague in the late Ming Dynasty and its prevention and control measures

The plague of the late Ming Dynasty(15511644 C.E.)was long lasting,affected a wide range of the population,and had serious consequences.The purpose of this study is to review the medical system in place at the time and the measures instituted to prevent and control the plague during the late Ming Dynasty.Information on the history of the Ming Dynasty(13681644 C.E.),local chronicles,and related research literature were consulted and analyzed in terms of duration,geographical area,and other dimensions of the epidemic.Because of the abnormal climate,wide range of natural disasters,and the impact of war,the epidemic spread over a wide area during the late Ming Dynasty.The government’s epidemic prevention measures were affected by war and other factors,resulting in poor control of the outbreak.However,in terms of the medical system in place during the Ming Dynasty,some of the thinking and methods of prevention and control of the plague were historical and progressive.Some outstanding physicians such as Wu Youke(15821652 C.E.)appeared during this period.His theory of plague prevention and control had a profound influence on the formation and development of pestilence deterrence in later generations.In the late Ming Dynasty,rich experiences and measures of prevention and control were accumulated in the struggle against the plague.These methods and experiences also have a significant,positive guiding influence on the prevention and control of plague in the present day.

Landscape Design of the Ming Dynasty Outer City Wall in Nanjing from the Perspective of Experience Tourism

Taking a section of the Ming Dynasty Outer City Wall from Xianhe Gate to Qilin Gate for example, this paper proposed the landscape design from the perspective of experience tourism, highlighted the wal, and took the beautiful environment and rich history and cultures of the Ming Dynasty Outer City Wall as the essential experience elements, to build cultural recreational corridors with the theme of "experiencing the Ming Dynasty culture", so that visitors will get unforgettable experience, tourism quality, popularity of the Ming Dynasty Outer City Wall as well as its cultural and educational significance will be further promoted.

Investigation of Vegetation Resources on City Wall of the Ming Dynasty in Nanjing City and Ecological Evaluation of the City Wall

Phyto-groups on 5 remained city wall sections of the Ming Dynasty in Nanjing City was investigated through on-the-spot survey,99 species of 93 genera,60 families were found,and species of Asteraceae and Poaceae accounted for the largest ratio.Plants on the city wall are characterized by strong drought resistance and precocity,their seeds can grow out of the wall cracks,and roots secrete acidoid and obtain nutrients from wall bricks.Plants on different wall sections are different,and human interventions influence phyto-groups on the city wall greatly.On this basis,it was concluded that plants had negative influence on city wall,especially plant roots destroyed the wall seriously.Corresponding researches were carried out and prevention suggestions proposed to provide scientific support for the protection of ancient city walls in Nanjing City.

Construction of the Sense of Belonging of Place Spirit in the Renovation of Historical Blocks: A Case Study of Ancient Town Street of Ming and Qing Dynasties in Hekou, Qianshan

The renovation of historical blocks often stays at the material level of buildings, ignoring the deeper spiritual level, which can not arouse people’s sense of belonging to the city memory. Based on the protection of local Qianshan area culture, taking Hekou ancient town street of Ming and Qing Dynasty as an example, with the construction of place spirit and sense of belonging as the primary goal, and combining the history and culture of the city, the current situation of the streets and the characteristics of the buildings, this paper put forward the relevant renovation measures to provide a kind of thinking for the refined and rational renovation of the blocks in the future.

Furniture of the Ming & Qing Dynasties

FOREIGNERShaveplayedapivotalroleincreatingtheMingandQingfurniturecollectioncraze.Collectorsbeganlookingforpiecesasearlyasthe17thcentury,whenfurniturewastakenfromimperialcourtsfollowingthedownfalloftheMingDynasty.Duringthe"culturalrevolution"(1966-76...