Computer aided process planning（CAPP） is an important content of computer integrated manufacturing, and intelligentizing is the orientation of development of CAPP. Process planning has characters of empirical and ti...Computer aided process planning（CAPP） is an important content of computer integrated manufacturing, and intelligentizing is the orientation of development of CAPP. Process planning has characters of empirical and time-consuming to finalize, and the same technical aim always can be achieved by different process schemes, so intelligentizing of process decision making always be a difficult point of CAPP and computer integrated manufacturing （CIM）. For the purpose of intelligent aided process decision making and reuse of process resource, this paper proposed a decision making method based on rough sets（RS） and regular distance computing. The main contents and methods of process planning decision making are analyzed under agile response manufacturing environment, the concept of process knowledge granule is represented, and the methods of process knowledge granule partitioning and granularity analysis are put forward. Based on the theory of RS and combined the method of process attributes importance identification, the paper brought forward a computing model for process scheme regulation distance under the same attribute conditions, and conflict resolution strategy was introduced to acquire process scheme fit for actual situation of enterprise＇s manufacturing resources, so as to realize process resources＇ conflict resolution and quick excavate and reuse of enterprises＇ existing process knowledge, to advance measures of process decision making and improve the rationality and capability of agile response of process planning.展开更多
LCRG1基因(laryngeal carcinoma related gene1,LCRG1)是一个新的喉癌候选抑瘤基因,其转录调控机制一直未被阐明.通过限制性内切酶酶切介导对LCRG1基因(-169～+127)区域进行剪切体分析,将LCRG1基因最小启动子定位于-169～-57.应用连接...LCRG1基因(laryngeal carcinoma related gene1,LCRG1)是一个新的喉癌候选抑瘤基因,其转录调控机制一直未被阐明.通过限制性内切酶酶切介导对LCRG1基因(-169～+127)区域进行剪切体分析,将LCRG1基因最小启动子定位于-169～-57.应用连接体扫描突变体分析,将关键顺式作用元件确定在-137～-122.生物信息学提示该区存在SP1、E2F1/DP1、EKLF和ZF9转录因子结合位点.利用已知反式作用因子与报告基因质粒进行共转染,提示Spl为有效的反式作用因子,且能上调LCRG1基因的表达.凝胶迁移阻滞实验确定LCRG1基因关键的顺式作用元件区域具有Spl结合位点.LCRG1基因启动子-137～-122片段在该基因表达过程中可能起重要作用,为LCRG1基因功能研究提供了新的证据.展开更多
This article presents a distributed periodic eventtriggered(PET)optimal control scheme to achieve generation cost minimization and average bus voltage regulation in DC microgrids.In order to accommodate the generation...This article presents a distributed periodic eventtriggered(PET)optimal control scheme to achieve generation cost minimization and average bus voltage regulation in DC microgrids.In order to accommodate the generation constraints of the distributed generators(DGs),a virtual incremental cost is firstly designed,based on which an optimality condition is derived to facilitate the control design.To meet the discrete-time(DT)nature of modern control systems,the optimal controller is directly developed in the DT domain.Afterward,to reduce the communication requirement among the controllers,a distributed event-triggered mechanism is introduced for the DT optimal controller.The event-triggered condition is detected periodically and therefore naturally avoids the Zeno phenomenon.The closed-loop system stability is proved by the Lyapunov synthesis for switched systems.The generation cost minimization and average bus voltage regulation are obtained at the equilibrium point.Finally,switch-level microgrid simulations validate the performance of the proposed optimal controller.展开更多
基金supported by National Key Technology R&D Program of China (Grant No. 2006BAF01A07)National Hi-tech Research and Development Program of China (863 Program, Grant No. 2007AA04Z190)
文摘Computer aided process planning（CAPP） is an important content of computer integrated manufacturing, and intelligentizing is the orientation of development of CAPP. Process planning has characters of empirical and time-consuming to finalize, and the same technical aim always can be achieved by different process schemes, so intelligentizing of process decision making always be a difficult point of CAPP and computer integrated manufacturing （CIM）. For the purpose of intelligent aided process decision making and reuse of process resource, this paper proposed a decision making method based on rough sets（RS） and regular distance computing. The main contents and methods of process planning decision making are analyzed under agile response manufacturing environment, the concept of process knowledge granule is represented, and the methods of process knowledge granule partitioning and granularity analysis are put forward. Based on the theory of RS and combined the method of process attributes importance identification, the paper brought forward a computing model for process scheme regulation distance under the same attribute conditions, and conflict resolution strategy was introduced to acquire process scheme fit for actual situation of enterprise＇s manufacturing resources, so as to realize process resources＇ conflict resolution and quick excavate and reuse of enterprises＇ existing process knowledge, to advance measures of process decision making and improve the rationality and capability of agile response of process planning.
文摘LCRG1基因(laryngeal carcinoma related gene1,LCRG1)是一个新的喉癌候选抑瘤基因,其转录调控机制一直未被阐明.通过限制性内切酶酶切介导对LCRG1基因(-169～+127)区域进行剪切体分析,将LCRG1基因最小启动子定位于-169～-57.应用连接体扫描突变体分析,将关键顺式作用元件确定在-137～-122.生物信息学提示该区存在SP1、E2F1/DP1、EKLF和ZF9转录因子结合位点.利用已知反式作用因子与报告基因质粒进行共转染,提示Spl为有效的反式作用因子,且能上调LCRG1基因的表达.凝胶迁移阻滞实验确定LCRG1基因关键的顺式作用元件区域具有Spl结合位点.LCRG1基因启动子-137～-122片段在该基因表达过程中可能起重要作用,为LCRG1基因功能研究提供了新的证据.
基金supported by the U.S.Office of Naval Research(N00014-21-1-2175)。
文摘This article presents a distributed periodic eventtriggered(PET)optimal control scheme to achieve generation cost minimization and average bus voltage regulation in DC microgrids.In order to accommodate the generation constraints of the distributed generators(DGs),a virtual incremental cost is firstly designed,based on which an optimality condition is derived to facilitate the control design.To meet the discrete-time(DT)nature of modern control systems,the optimal controller is directly developed in the DT domain.Afterward,to reduce the communication requirement among the controllers,a distributed event-triggered mechanism is introduced for the DT optimal controller.The event-triggered condition is detected periodically and therefore naturally avoids the Zeno phenomenon.The closed-loop system stability is proved by the Lyapunov synthesis for switched systems.The generation cost minimization and average bus voltage regulation are obtained at the equilibrium point.Finally,switch-level microgrid simulations validate the performance of the proposed optimal controller.
