A new method for preparation of the potent hypoglycemic KAD-1229 was developed. The key step of this method is diasteroselective alkylation in high optical purity and good yield by using easily available Oppolzer’s...A new method for preparation of the potent hypoglycemic KAD-1229 was developed. The key step of this method is diasteroselective alkylation in high optical purity and good yield by using easily available Oppolzer’s camphor sultam as chiral auxiliary.展开更多
文摘A new method for preparation of the potent hypoglycemic KAD-1229 was developed. The key step of this method is diasteroselective alkylation in high optical purity and good yield by using easily available Oppolzer’s camphor sultam as chiral auxiliary.
