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Complementarity of CFD,experimentation and reactor models for solving challenging fluidization problems 被引量:4
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作者 John R. Grace Tingwen Li 《Particuology》 SCIE EI CAS CSCD 2010年第6期498-500,共3页
Experimentalists, numerical modellers and reactor modellers need to work together, not only just for validation of numerical codes, but also to shed fundamental light on each other's problems and underlying assumptio... Experimentalists, numerical modellers and reactor modellers need to work together, not only just for validation of numerical codes, but also to shed fundamental light on each other's problems and underlying assumptions. Several examples are given, Experimental gas axial dispersion data provide a means of choosing the most appropriate boundary condition (no slip, partial slip or full slip) for particles at the wall of fluidized beds. CFD simulations help to identify how close "two-dimensional" experimental columns are to being truly two-dimensional and to representing three-dimensional columns. CFD also can be used to provide a more rational means of establishing assumptions needed in the modelling of two-phase fluidized bed reactors, for example how to deal with cases where there is a change in molar flow (and hence volumetric flow) as a result of chemical reactions. 展开更多
关键词 Fluidization Mixing Computational Fluid dynamics Wall slip reactor modelling Volume change
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采用流体反应器连续制备可用于T_(1)加权磁共振成像的极小尺寸氧化铁纳米颗粒 被引量:2
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作者 毛宇 李艳 +8 位作者 臧凤超 于昊立 严森 宋青松 秦志国 孙剑飞 陈博 黄晓 顾宁 《Science China Materials》 SCIE EI CAS CSCD 2022年第6期1646-1654,共9页
粒径小于5 nm的极小尺寸氧化铁纳米颗粒(ESIONPs)作为T_(1)加权磁共振成像(T_(1)-MRI)造影剂展现出巨大的发展前景.然而,具有良好生物相容性的ESIONPs的批量生产仍然难以实现.本研究通过特别设计的气/液混合相流体反应器结合共沉淀合成... 粒径小于5 nm的极小尺寸氧化铁纳米颗粒(ESIONPs)作为T_(1)加权磁共振成像(T_(1)-MRI)造影剂展现出巨大的发展前景.然而,具有良好生物相容性的ESIONPs的批量生产仍然难以实现.本研究通过特别设计的气/液混合相流体反应器结合共沉淀合成方法,实现了聚葡萄糖山梨醇羧甲基醚(PSC)包覆的ESIONPs的连续制备,且其粒径在1.8–4.0 nm范围内可控.在不同粒径的ESIONPs中,粒径为3.7 nm的ESIONPs具有最好的T_(1)-MRI造影效果,特别是在临床3 T磁共振扫描设备下具有高的r_(1)值(4.11(mmol L^(−1))^(−1)s^(−1))和低的r_(2)/r_(1)值(7.90),并且在水相、细胞和血管环境中均展现出良好的T_(1)-MRI对比效果.此外,PSC包覆的ESIONPs具有良好的生物安全性,在水相中具有良好的分散性和长期稳定性,有望成为临床可用的安全有效的T_(1)-MRI造影剂. 展开更多
关键词 ESIONPs T1-contrast agents MRI coprecipitation method gas/liquid mixed phase fluidic reactor
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