Urban traffic volume detection is an essential part of trafficplanning in terms of urban planning in China. To improve the statisticsefficiency of road traffic volume, this thesis proposes a method for predictingmotor...Urban traffic volume detection is an essential part of trafficplanning in terms of urban planning in China. To improve the statisticsefficiency of road traffic volume, this thesis proposes a method for predictingmotor vehicle traffic volume on urban roads in small and medium-sizedcities during the traffic peak hour by using mobile signal technology. Themethod is verified through simulation experiments, and the limitations andthe improvement methods are discussed. This research can be divided intothree parts: Firstly, the traffic patterns of small and medium-sized cities areobtained through a questionnaire survey. A total of 19745 residents weresurveyed in Luohe, a medium-sized city in China and five travel modes oflocal people were obtained. Secondly, after the characteristics of residents’rest and working time are investigated, a method is proposed in this studyfor the distribution of urban residential and working places based on mobilephone signaling technology. Finally, methods for predicting traffic volume ofthese travel modes are proposed after the characteristics of these travel modesand methods for the distribution of urban residential and working placesare analyzed. Based on the actual traffic volume data observed at offlineintersections, the project team takes Luohe city as the research object and itverifies the accuracy of the prediction method by comparing the predictiondata. The prediction simulation results of traffic volume show that the averageerror rate of traffic volume is unstable. The error rate ranges from 10% to 30%.In this thesis, simulation experiments and field investigations are adopted toanalyze why these errors occur.展开更多
In view of the many scenes of unmanned aerial vehicle(UAV)detection,a third-party signal source is used to design a receiver to monitor the UAV.It is of great significance to understand the reflection of the signal il...In view of the many scenes of unmanned aerial vehicle(UAV)detection,a third-party signal source is used to design a receiver to monitor the UAV.It is of great significance to understand the reflection of the signal illuminating the UAV.Taking the communication base station(BS)signal as the third-party signal source,and considering the complete transmission link,reflection changes and loss fading of the communication signal,this study conducts model fitting for irregular UAV targets,simplifying complex targets into a combination of simple targets.Furthermore,the influence of the dielectric constant of the target surface and the signal irradiation angle on the signal reflection is analyzed.The analysis shows that the simulation results of this model fitting method are consistent with the results of other literature,which provides theoretical support for the detection of low and slow small targets such as UAVs.展开更多
Phased small interfering RNAs(phasiRNAs) are abundantly expressed in anthers and linked to environment-related male fertility in grasses, yet how they function under different environmental conditions remains unclear....Phased small interfering RNAs(phasiRNAs) are abundantly expressed in anthers and linked to environment-related male fertility in grasses, yet how they function under different environmental conditions remains unclear. Here, we identified a rice(Oryza sativa) low temperature-induced Argonaute(AGO) protein, OsAGO1d, that is responsible for generating phasiRNAs and preserving male fertility at low temperature. Loss of OsAGO1d function causes low-temperature male sterility associated with delayed programmed cell death of tapetal cells during anther development. OsAGO1d binds miR2118 and miR2275 family members and triggers phasiRNA biogenesis;it also binds 21-nt phasiRNAs with a 5′ terminal U. In total, phasiRNAs from 972loci are OsAGO1d-dependent. OsAGO1d protein moves from anther wall cells into meiocytes, where it loads miR2275 to produce 24-nt phasiRNAs. Together, our results show that OsAGO1d acts as a mobile signal to fine-tune phasiRNA production and this function is important for male fertility at low temperature.展开更多
The concept advanced by Berridge and colleagues that intracellular Ca2+-stores can be mobilized in an agonist-dependent and messenger(IP3)-mediated manner has put Ca 2+-mobilization at the center stage of signal trans...The concept advanced by Berridge and colleagues that intracellular Ca2+-stores can be mobilized in an agonist-dependent and messenger(IP3)-mediated manner has put Ca 2+-mobilization at the center stage of signal transduction mechanisms.During the late 1980s,we showed that Ca2+-stores can be mobilized by two other messengers unrelated to inositol trisphosphate(IP 3) and identified them as cyclic ADP-ribose(cADPR),a novel cyclic nucleotide from NAD,and nicotinic acid adenine dinucleotide phosphate(NAADP),a linear metabolite of NADP.Their messenger functions have now been documented in a wide range of systems spanning three biological kingdoms.Accumulated evidence indicates that the target of cADPR is the ryanodine receptor in the sarco/endoplasmic reticulum,while that of NAADP is the two pore channel in endolysosomes. As cADPR and NAADP are structurally and functionally distinct,it is remarkable that they are synthesized by the same enzyme.They are thus fraternal twin messengers.We first identified the Aplysia ADP-ribosyl cyclase as one such enzyme and,through homology,found its mammalian homolog,CD38.Gene knockout in mice confirms the important roles of CD38 in diverse physiological functions from insulin secretion,susceptibility to bacterial infection,to social behavior of mice through modulating neuronal oxytocin secretion.We have elucidated the catalytic mechanisms of the Aplysia cyclase and CD38 to atomic resolution by crystallography and site-directed mutagenesis.This article gives a historical account of the cADPR/NAADP/CD38-signaling pathway and describes current efforts in elucidating the structure and function of its components.展开更多
The complexity and fragmentation of people’s activity space are challenging to planners.However,the relevant studies are mostly concerned on the relationship between the social attributes and the activity space of re...The complexity and fragmentation of people’s activity space are challenging to planners.However,the relevant studies are mostly concerned on the relationship between the social attributes and the activity space of residents in a single or several communities,or the spatiotemporal laws of activity space on a macro scale.The research on the spatial characteristics of residents’activity space still needs to be strengthened.The present study analyses the spatial patterns of residents’activity space based on mobile phone signaling data to fill the gap of previous studies that assessed residents’activity space across small geographic areas.First,according to the spatial scope and direction of an activity space and residents’activity coverage rate,spatial patterns can be divided into three types:compact,extended,and directional extension patterns.The CatBoost method is then used to statistically analyze the influencing variables of spatial patterns,and the order of importance of the following influencing factors is determined:the built environment is more influential than social and economic situations.This study aims to strengthen the understanding of residents’activity space at the spatial level and provide a basis for the optimization of communities with different spatial patterns.展开更多
This paper identifies the employment and housing locations of residents in Shanghai based on mobile phone signaling data, so as to obtain the employment density and commuting data and analyze the development of nine s...This paper identifies the employment and housing locations of residents in Shanghai based on mobile phone signaling data, so as to obtain the employment density and commuting data and analyze the development of nine suburban new towns from the perspective of jobs-housing spatial relationship. Firstly, the paper defines employment-intensive areas and gets the average employment density of each new town according to the employment density data. Then it marks out the scope of the employment influence through analyzing the sources of workers in each new town in accordance with the commuting data. Finally, it analyzes the jobs-housing balance of each new town using independence index, finding that suburban new towns in Shanghai have become main clusters of economic activities, while the scope of employment influence in each new town is still concentrated in its administrative area, with less attraction to residents in other areas. The independence index demonstrates a law that the suburban new town which is farther from the central city sees a higher degree of jobs-housing balance. Among them, new towns located in the outer suburbs with a low independence index indicate their special development situation, the reason of which is worth further study.展开更多
文摘Urban traffic volume detection is an essential part of trafficplanning in terms of urban planning in China. To improve the statisticsefficiency of road traffic volume, this thesis proposes a method for predictingmotor vehicle traffic volume on urban roads in small and medium-sizedcities during the traffic peak hour by using mobile signal technology. Themethod is verified through simulation experiments, and the limitations andthe improvement methods are discussed. This research can be divided intothree parts: Firstly, the traffic patterns of small and medium-sized cities areobtained through a questionnaire survey. A total of 19745 residents weresurveyed in Luohe, a medium-sized city in China and five travel modes oflocal people were obtained. Secondly, after the characteristics of residents’rest and working time are investigated, a method is proposed in this studyfor the distribution of urban residential and working places based on mobilephone signaling technology. Finally, methods for predicting traffic volume ofthese travel modes are proposed after the characteristics of these travel modesand methods for the distribution of urban residential and working placesare analyzed. Based on the actual traffic volume data observed at offlineintersections, the project team takes Luohe city as the research object and itverifies the accuracy of the prediction method by comparing the predictiondata. The prediction simulation results of traffic volume show that the averageerror rate of traffic volume is unstable. The error rate ranges from 10% to 30%.In this thesis, simulation experiments and field investigations are adopted toanalyze why these errors occur.
基金supported by the State Major Research and Development Project(2018YFB1802004)the State Key Laboratory of Air Traffic Management System and Technology(SKLATM201807)。
文摘In view of the many scenes of unmanned aerial vehicle(UAV)detection,a third-party signal source is used to design a receiver to monitor the UAV.It is of great significance to understand the reflection of the signal illuminating the UAV.Taking the communication base station(BS)signal as the third-party signal source,and considering the complete transmission link,reflection changes and loss fading of the communication signal,this study conducts model fitting for irregular UAV targets,simplifying complex targets into a combination of simple targets.Furthermore,the influence of the dielectric constant of the target surface and the signal irradiation angle on the signal reflection is analyzed.The analysis shows that the simulation results of this model fitting method are consistent with the results of other literature,which provides theoretical support for the detection of low and slow small targets such as UAVs.
基金supported by the National Natural Science Foundation of China(31788103,32170620)the Chinese Academy of Sciences(QYZDY-SSW-SMC022,XDB27030201,XDA24010302)the State Key Laboratory of Plant Genomics。
文摘Phased small interfering RNAs(phasiRNAs) are abundantly expressed in anthers and linked to environment-related male fertility in grasses, yet how they function under different environmental conditions remains unclear. Here, we identified a rice(Oryza sativa) low temperature-induced Argonaute(AGO) protein, OsAGO1d, that is responsible for generating phasiRNAs and preserving male fertility at low temperature. Loss of OsAGO1d function causes low-temperature male sterility associated with delayed programmed cell death of tapetal cells during anther development. OsAGO1d binds miR2118 and miR2275 family members and triggers phasiRNA biogenesis;it also binds 21-nt phasiRNAs with a 5′ terminal U. In total, phasiRNAs from 972loci are OsAGO1d-dependent. OsAGO1d protein moves from anther wall cells into meiocytes, where it loads miR2275 to produce 24-nt phasiRNAs. Together, our results show that OsAGO1d acts as a mobile signal to fine-tune phasiRNA production and this function is important for male fertility at low temperature.
基金supported by the Research Grants Council of Hong Kong(Grant Nos.769107,768408, 769309 and 770610)the National Natural Science Foundation of China/the Research Grants Council of Hong Kong(Grant No.N_HKU 722/08)
文摘The concept advanced by Berridge and colleagues that intracellular Ca2+-stores can be mobilized in an agonist-dependent and messenger(IP3)-mediated manner has put Ca 2+-mobilization at the center stage of signal transduction mechanisms.During the late 1980s,we showed that Ca2+-stores can be mobilized by two other messengers unrelated to inositol trisphosphate(IP 3) and identified them as cyclic ADP-ribose(cADPR),a novel cyclic nucleotide from NAD,and nicotinic acid adenine dinucleotide phosphate(NAADP),a linear metabolite of NADP.Their messenger functions have now been documented in a wide range of systems spanning three biological kingdoms.Accumulated evidence indicates that the target of cADPR is the ryanodine receptor in the sarco/endoplasmic reticulum,while that of NAADP is the two pore channel in endolysosomes. As cADPR and NAADP are structurally and functionally distinct,it is remarkable that they are synthesized by the same enzyme.They are thus fraternal twin messengers.We first identified the Aplysia ADP-ribosyl cyclase as one such enzyme and,through homology,found its mammalian homolog,CD38.Gene knockout in mice confirms the important roles of CD38 in diverse physiological functions from insulin secretion,susceptibility to bacterial infection,to social behavior of mice through modulating neuronal oxytocin secretion.We have elucidated the catalytic mechanisms of the Aplysia cyclase and CD38 to atomic resolution by crystallography and site-directed mutagenesis.This article gives a historical account of the cADPR/NAADP/CD38-signaling pathway and describes current efforts in elucidating the structure and function of its components.
基金This work was supported by the National Natural Science Foundation of China[grant numbers 51778125].
文摘The complexity and fragmentation of people’s activity space are challenging to planners.However,the relevant studies are mostly concerned on the relationship between the social attributes and the activity space of residents in a single or several communities,or the spatiotemporal laws of activity space on a macro scale.The research on the spatial characteristics of residents’activity space still needs to be strengthened.The present study analyses the spatial patterns of residents’activity space based on mobile phone signaling data to fill the gap of previous studies that assessed residents’activity space across small geographic areas.First,according to the spatial scope and direction of an activity space and residents’activity coverage rate,spatial patterns can be divided into three types:compact,extended,and directional extension patterns.The CatBoost method is then used to statistically analyze the influencing variables of spatial patterns,and the order of importance of the following influencing factors is determined:the built environment is more influential than social and economic situations.This study aims to strengthen the understanding of residents’activity space at the spatial level and provide a basis for the optimization of communities with different spatial patterns.
文摘This paper identifies the employment and housing locations of residents in Shanghai based on mobile phone signaling data, so as to obtain the employment density and commuting data and analyze the development of nine suburban new towns from the perspective of jobs-housing spatial relationship. Firstly, the paper defines employment-intensive areas and gets the average employment density of each new town according to the employment density data. Then it marks out the scope of the employment influence through analyzing the sources of workers in each new town in accordance with the commuting data. Finally, it analyzes the jobs-housing balance of each new town using independence index, finding that suburban new towns in Shanghai have become main clusters of economic activities, while the scope of employment influence in each new town is still concentrated in its administrative area, with less attraction to residents in other areas. The independence index demonstrates a law that the suburban new town which is farther from the central city sees a higher degree of jobs-housing balance. Among them, new towns located in the outer suburbs with a low independence index indicate their special development situation, the reason of which is worth further study.