The binding mode and configuration of cisplatin with F-actin were studied on the basis of charge transfer bands of cisplatin-F-actin complex The binding mode was discussed on the basis of the results of LMCT.Raman and...The binding mode and configuration of cisplatin with F-actin were studied on the basis of charge transfer bands of cisplatin-F-actin complex The binding mode was discussed on the basis of the results of LMCT.Raman and fluorescence spectra.展开更多
Nowadays harmful gas in vehicle exhaust has pollute d air heavily. To prevent the environment from polluting, the request of emissions control legislation becomes more stringent. New legislation prescribes not only th...Nowadays harmful gas in vehicle exhaust has pollute d air heavily. To prevent the environment from polluting, the request of emissions control legislation becomes more stringent. New legislation prescribes not only the emissions limitation of vehicles, but also testing instruments and methods. Test car must be operated on the chassis dynamometer and data must be collect ed and analyzed with prescriptive exhaust analysis system as well. The mass of harmful exhaust gas, containing the concentration and volume of emis sion, which is independent from the model of automobile and engine, can be used as a criterion to evaluate the pollution of an automobile. Constant Volume Sampl e System (CVS) is used to measure vehicle emissions, but it is too expensive to apply extensively. The Vehicle Mass Analysis System(Vmas), a new vehicle exhaust mass analysis system produced in USA late 1990s,is used to test and analyze veh icle exhaust. As a test instrument, it has the virtue of cheapness and easy mana geability. In this paper, Vmas is used to measure the emissions of a light truck CA1020F. A ccording to 15 running modes of Vehicle Exhaust Legislation, the test car is ope rated on the chassis dynamometer and data are collected and analyzed with Vmas. The test results show that it is viable to measure and evaluate automobile emiss ion with Vmas. Most of HC exhaust is produced when the car is decelerating. The major factor that influences the mass of HC emission is the sudden decrease of e ngine load causing incomplete combustion in decelerating mode. Test results indi cate CO and NOx are mainly produced in the process of increasing load. The forme r reason is incomplete combustion and the latter is high burning temperature cau sed by the increasing load. The methods of reducing automobile emission are also discussed in this paper.展开更多
A selective and rapid high-performance liquid chromatography–tandem mass spectrometry method was developed and validated for the quantification of raltegravir using raltegravir-d3 as an internal standard（IS）. The a...A selective and rapid high-performance liquid chromatography–tandem mass spectrometry method was developed and validated for the quantification of raltegravir using raltegravir-d3 as an internal standard（IS）. The analyte and IS were extracted with methylene chloride and n-hexane solvent mixture from 100 mL human plasma. The chromatographic separation was achieved on a Chromolith RP-18 e endcapped C18（100 mm 4.6 mm） column in a run time of 2.0 min. Quantitation was performed in the negative ionization mode using the transitions of m/z 443.1-316.1 for raltegravir and m/z 446.1-319.0 for IS. The linearity of the method was established in the concentration range of 2.0–6000 ng/m L.The mean extraction recovery for raltegravir and IS was 92.6% and 91.8%, respectively, and the IS-normalized matrix factors for raltegravir ranged from 0.992 to 0.999. The application of this method was demonstrated by a bioequivalence study on 18 healthy subjects.展开更多
InGaAsP semiconductor ETR microlasers with side length of 5 and 10 um are fabricated by ICP etching. The peaks in photoluminenscent spectra corresponding to longitudinal modes are observed with the interval consisting...InGaAsP semiconductor ETR microlasers with side length of 5 and 10 um are fabricated by ICP etching. The peaks in photoluminenscent spectra corresponding to longitudinal modes are observed with the interval consisting with the theoretical formulae.展开更多
In this paper we present the Brillouin Scattering measurements of the longitudinal and transverse sound velocities for the hexahalome-atllate K2SnCl6 at room temperature . The elastic constants , refractive index , vo...In this paper we present the Brillouin Scattering measurements of the longitudinal and transverse sound velocities for the hexahalome-atllate K2SnCl6 at room temperature . The elastic constants , refractive index , volume compressibility are determined from the Brillouin line shifts. Furthermore, the sound velocity in the [111] direction is investigated as a function of temperature 252K<T<270K . An acoustic adrupt change of the c11+2c12 mode is observed as the temperature approaches 256K from above, which has been analysed by means of the Pippard relations. The conclusion is that K2SnCl6 undergoes first order phase transition near T=256K. This acoustic anomaly can be interpreted by the nonlinear coupling of the elastic strain field to the fluctuation of the soft-mode coordinate.展开更多
文摘The binding mode and configuration of cisplatin with F-actin were studied on the basis of charge transfer bands of cisplatin-F-actin complex The binding mode was discussed on the basis of the results of LMCT.Raman and fluorescence spectra.
文摘Nowadays harmful gas in vehicle exhaust has pollute d air heavily. To prevent the environment from polluting, the request of emissions control legislation becomes more stringent. New legislation prescribes not only the emissions limitation of vehicles, but also testing instruments and methods. Test car must be operated on the chassis dynamometer and data must be collect ed and analyzed with prescriptive exhaust analysis system as well. The mass of harmful exhaust gas, containing the concentration and volume of emis sion, which is independent from the model of automobile and engine, can be used as a criterion to evaluate the pollution of an automobile. Constant Volume Sampl e System (CVS) is used to measure vehicle emissions, but it is too expensive to apply extensively. The Vehicle Mass Analysis System(Vmas), a new vehicle exhaust mass analysis system produced in USA late 1990s,is used to test and analyze veh icle exhaust. As a test instrument, it has the virtue of cheapness and easy mana geability. In this paper, Vmas is used to measure the emissions of a light truck CA1020F. A ccording to 15 running modes of Vehicle Exhaust Legislation, the test car is ope rated on the chassis dynamometer and data are collected and analyzed with Vmas. The test results show that it is viable to measure and evaluate automobile emiss ion with Vmas. Most of HC exhaust is produced when the car is decelerating. The major factor that influences the mass of HC emission is the sudden decrease of e ngine load causing incomplete combustion in decelerating mode. Test results indi cate CO and NOx are mainly produced in the process of increasing load. The forme r reason is incomplete combustion and the latter is high burning temperature cau sed by the increasing load. The methods of reducing automobile emission are also discussed in this paper.
文摘A selective and rapid high-performance liquid chromatography–tandem mass spectrometry method was developed and validated for the quantification of raltegravir using raltegravir-d3 as an internal standard（IS）. The analyte and IS were extracted with methylene chloride and n-hexane solvent mixture from 100 mL human plasma. The chromatographic separation was achieved on a Chromolith RP-18 e endcapped C18（100 mm 4.6 mm） column in a run time of 2.0 min. Quantitation was performed in the negative ionization mode using the transitions of m/z 443.1-316.1 for raltegravir and m/z 446.1-319.0 for IS. The linearity of the method was established in the concentration range of 2.0–6000 ng/m L.The mean extraction recovery for raltegravir and IS was 92.6% and 91.8%, respectively, and the IS-normalized matrix factors for raltegravir ranged from 0.992 to 0.999. The application of this method was demonstrated by a bioequivalence study on 18 healthy subjects.
文摘InGaAsP semiconductor ETR microlasers with side length of 5 and 10 um are fabricated by ICP etching. The peaks in photoluminenscent spectra corresponding to longitudinal modes are observed with the interval consisting with the theoretical formulae.
文摘In this paper we present the Brillouin Scattering measurements of the longitudinal and transverse sound velocities for the hexahalome-atllate K2SnCl6 at room temperature . The elastic constants , refractive index , volume compressibility are determined from the Brillouin line shifts. Furthermore, the sound velocity in the [111] direction is investigated as a function of temperature 252K<T<270K . An acoustic adrupt change of the c11+2c12 mode is observed as the temperature approaches 256K from above, which has been analysed by means of the Pippard relations. The conclusion is that K2SnCl6 undergoes first order phase transition near T=256K. This acoustic anomaly can be interpreted by the nonlinear coupling of the elastic strain field to the fluctuation of the soft-mode coordinate.
