Background:Biochemical and hematological parameters are important tools for assessing the physiological profile of vital organs,and can be recorded to create reference values used for clinical diagnosis of diseases.Ma...Background:Biochemical and hematological parameters are important tools for assessing the physiological profile of vital organs,and can be recorded to create reference values used for clinical diagnosis of diseases.Many research laboratories lack the means to establish their own set of reference parameters for use in their research,and while there are articles in the literature that discuss laboratory parameters for healthy BALB/c mice,few studies address the evaluation of these parameters in pathological situations,such as in mice inoculated with Ehrlich tumor.Method:BALB/c-FMABC mice previously inoculated with Ehrlich tumor were maintained under appropriate conditions.Blood samples were taken for analysis of hematological parameters using automated and semi-automated equipment to create a set of the animal welfare parameters for evaluation.Result:Results were obtained for all the hematological parameters for all groups analyzed.These showed:statistically significant differences between the initial and final tumor weight;comparable initial tumour volume and weight;an increase in leukocytes in the 7-day group with a characteristic predominance of lymphocytes and neutrophils;statistically significant changes in RDW in the 21-day group and in the welfare parameters in the 28-day group.Conclusion:The study successfully defined and established reference values for hematological and welfare parameters for all groups analyzed.展开更多
Empirical research was done interviewing face to face a sample of 2,447, 10-12 grade students in Culiacan, Sinaloa, Mexico, from the main public university high school in town. Education is seen as a tool to develop b...Empirical research was done interviewing face to face a sample of 2,447, 10-12 grade students in Culiacan, Sinaloa, Mexico, from the main public university high school in town. Education is seen as a tool to develop better citizens first, and better workers later. The objective of this research was to detect different perceptions related to values and education. Using a 13 items questionnaire, we measured： Students＇ perceptions about him/herself as part of their education role, responsibility that students show toward activities m school, perceptions about education as a tool to grow in the social ladder and as a way of social recognition, social perception about effort as an important value to self-improve and get social recognition, and to finish, perceptions about their teacher＇s performance.展开更多
Most left ventricular(LV)Doppler measurements vary significantly with age and gender,making it necessary to correct them for physiological variances.We aimed to verify the hypothesis that different Doppler measurement...Most left ventricular(LV)Doppler measurements vary significantly with age and gender,making it necessary to correct them for physiological variances.We aimed to verify the hypothesis that different Doppler measurements correlate nonlinearly with different biometric variables raised to different scaling factors and exponents.In this work,a total of 23 LV Doppler parameters were measured in 1224 healthy Chinese adults.An optimized multivariable allometric model(OMAM)and scaling equations were developed in 70%of the subjects(group A),and the reliability of the model and equations was verified using the remaining 30%of the subjects(group B)as well as 183 overweight subjects(group C).The single-variable isometric model(SVIM)with body surface area(BSA)as a scaling variable was used for comparison.Before correction,all 23 LV Doppler parameters correlated significantly with one or more of the biometric variables.In group B,gender differences were found in 47.8%(11/23)of the parameters and were eliminated in 81.8%(9/11)of the parameters after correction with OMAM.The successful correction rate with OMAM was 100%(23/23)in group B and 82.6%(19/23)in group C.New reference values for corrected Doppler measurements independent of biometric variables were established.The SVIM with BSA successfully corrected none of the 23 parameters.In conclusion,different LV Doppler parameters allometrically correlated with one or more of the biometric variables.The novel OMAM developed in this study successfully corrected the effects of the physiological variances of most biometric variables on Doppler measurements in healthy and overweight subjects,and was found to be far superior to the SVIM.However,whether the OMAM equations can be applied to other ethnicities,obese subjects,and pathological conditions requires further investigation.展开更多
通过分析历史上的经典战例,结合对指挥控制(Command and Control,C2)内涵解读,揭示成功的C2本质特征是:既源自时代,又超越时代。如今各类军事/非军事行动的主体、环境及相互关系均发生了巨大变化,这加剧了C2的复杂性和不确定性。由此,...通过分析历史上的经典战例,结合对指挥控制(Command and Control,C2)内涵解读,揭示成功的C2本质特征是:既源自时代,又超越时代。如今各类军事/非军事行动的主体、环境及相互关系均发生了巨大变化,这加剧了C2的复杂性和不确定性。由此,着重总结了西方学者近20年来在C2方面所取得的重大进展,提出了C2概念模型、建立网络使能的C2成熟度模型和C2敏捷性概念模型等;以空军“杀伤链”为例,剖析了由300多种/类的变量及其关系,到事件、决策和行动整个打击过程中的价值链映射。展开更多
文摘Background:Biochemical and hematological parameters are important tools for assessing the physiological profile of vital organs,and can be recorded to create reference values used for clinical diagnosis of diseases.Many research laboratories lack the means to establish their own set of reference parameters for use in their research,and while there are articles in the literature that discuss laboratory parameters for healthy BALB/c mice,few studies address the evaluation of these parameters in pathological situations,such as in mice inoculated with Ehrlich tumor.Method:BALB/c-FMABC mice previously inoculated with Ehrlich tumor were maintained under appropriate conditions.Blood samples were taken for analysis of hematological parameters using automated and semi-automated equipment to create a set of the animal welfare parameters for evaluation.Result:Results were obtained for all the hematological parameters for all groups analyzed.These showed:statistically significant differences between the initial and final tumor weight;comparable initial tumour volume and weight;an increase in leukocytes in the 7-day group with a characteristic predominance of lymphocytes and neutrophils;statistically significant changes in RDW in the 21-day group and in the welfare parameters in the 28-day group.Conclusion:The study successfully defined and established reference values for hematological and welfare parameters for all groups analyzed.
文摘Empirical research was done interviewing face to face a sample of 2,447, 10-12 grade students in Culiacan, Sinaloa, Mexico, from the main public university high school in town. Education is seen as a tool to develop better citizens first, and better workers later. The objective of this research was to detect different perceptions related to values and education. Using a 13 items questionnaire, we measured： Students＇ perceptions about him/herself as part of their education role, responsibility that students show toward activities m school, perceptions about education as a tool to grow in the social ladder and as a way of social recognition, social perception about effort as an important value to self-improve and get social recognition, and to finish, perceptions about their teacher＇s performance.
基金supported by the Program of Introducing Talents of Discipline to Universities(BP 0719033)the State Key Program of the National Natural Science Foundation of China(82030051)+4 种基金the International Collaboration and Exchange Program of China(81920108003)the National Natural Science Foundation of China(81671703,81770442,and 11771408)the Qingdao Key Health Discipline Development Fund(3311000000073)the People’s Livelihood Science and Technology Project of Qingdao(18-6-1-62-nsh)the Fundamental Research Funds for the Central Universities(201964006)。
文摘Most left ventricular(LV)Doppler measurements vary significantly with age and gender,making it necessary to correct them for physiological variances.We aimed to verify the hypothesis that different Doppler measurements correlate nonlinearly with different biometric variables raised to different scaling factors and exponents.In this work,a total of 23 LV Doppler parameters were measured in 1224 healthy Chinese adults.An optimized multivariable allometric model(OMAM)and scaling equations were developed in 70%of the subjects(group A),and the reliability of the model and equations was verified using the remaining 30%of the subjects(group B)as well as 183 overweight subjects(group C).The single-variable isometric model(SVIM)with body surface area(BSA)as a scaling variable was used for comparison.Before correction,all 23 LV Doppler parameters correlated significantly with one or more of the biometric variables.In group B,gender differences were found in 47.8%(11/23)of the parameters and were eliminated in 81.8%(9/11)of the parameters after correction with OMAM.The successful correction rate with OMAM was 100%(23/23)in group B and 82.6%(19/23)in group C.New reference values for corrected Doppler measurements independent of biometric variables were established.The SVIM with BSA successfully corrected none of the 23 parameters.In conclusion,different LV Doppler parameters allometrically correlated with one or more of the biometric variables.The novel OMAM developed in this study successfully corrected the effects of the physiological variances of most biometric variables on Doppler measurements in healthy and overweight subjects,and was found to be far superior to the SVIM.However,whether the OMAM equations can be applied to other ethnicities,obese subjects,and pathological conditions requires further investigation.
文摘通过分析历史上的经典战例,结合对指挥控制(Command and Control,C2)内涵解读,揭示成功的C2本质特征是:既源自时代,又超越时代。如今各类军事/非军事行动的主体、环境及相互关系均发生了巨大变化,这加剧了C2的复杂性和不确定性。由此,着重总结了西方学者近20年来在C2方面所取得的重大进展,提出了C2概念模型、建立网络使能的C2成熟度模型和C2敏捷性概念模型等;以空军“杀伤链”为例,剖析了由300多种/类的变量及其关系,到事件、决策和行动整个打击过程中的价值链映射。
