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SVM with Quadratic Polynomial Kernel Function Based Nonlinear Model One-step-ahead Predictive Control 被引量:12
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作者 钟伟民 何国龙 +1 位作者 皮道映 孙优贤 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2005年第3期373-379,共7页
A support vector machine (SVM) with quadratic polynomial kernel function based nonlinear model one-step-ahead predictive controller is presented. The SVM based predictive model is established with black-box identifica... A support vector machine (SVM) with quadratic polynomial kernel function based nonlinear model one-step-ahead predictive controller is presented. The SVM based predictive model is established with black-box identification method. By solving a cubic equation in the feature space, an explicit predictive control law is obtained through the predictive control mechanism. The effect of controller is demonstrated on a recognized benchmark problem and on the control of continuous-stirred tank reactor (CSTR). Simulation results show that SVM with quadratic polynomial kernel function based predictive controller can be well applied to nonlinear systems, with good performance in following reference trajectory as well as in disturbance-rejection. 展开更多
关键词 nonlinear model predictive control support vector machine nonlinear system identification kernel function
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TIVOLI AUDIO Model One收音机
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作者 叶新海 《视听技术》 2003年第11期43-44,共2页
曾经在我们(或许是我们的父辈们)的业余生活中扮演重要角色的收音机。如今已风光不再。确实,无线电广播比不了电视和互联网的声形并茂,单纯讲听音,又不及CD的高保真效果,从发展趋势来看,由“主角”退居“配角”地位自在情理之中。... 曾经在我们(或许是我们的父辈们)的业余生活中扮演重要角色的收音机。如今已风光不再。确实,无线电广播比不了电视和互联网的声形并茂,单纯讲听音,又不及CD的高保真效果,从发展趋势来看,由“主角”退居“配角”地位自在情理之中。不过无论时代如何变化,广播依然有它独特的魅力。首先,它是一种低成本的娱乐方式。相对于高保真音响器材而言。买台收音机的花费很少,收听节目更是无需花钱, 展开更多
关键词 TIVOLI 收音机 AUDIO model one 无线电广播 业余生活 发展趋势 娱乐方式 音响器材 高保真 互联网 电视 听音
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Parameter calibration of the tensile-shear interactive damage constitutive model for sandstone failure
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作者 Yun Shu Zheming Zhu +4 位作者 Meng Wang Weiting Gao Fei Wang Duanying Wan Yuntao Wang 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第4期1153-1174,共22页
The tensile-shear interactive damage(TSID)model is a novel and powerful constitutive model for rock-like materials.This study proposes a methodology to calibrate the TSID model parameters to simulate sandstone.The bas... The tensile-shear interactive damage(TSID)model is a novel and powerful constitutive model for rock-like materials.This study proposes a methodology to calibrate the TSID model parameters to simulate sandstone.The basic parameters of sandstone are determined through a series of static and dynamic tests,including uniaxial compression,Brazilian disc,triaxial compression under varying confining pressures,hydrostatic compression,and dynamic compression and tensile tests with a split Hopkinson pressure bar.Based on the sandstone test results from this study and previous research,a step-by-step procedure for parameter calibration is outlined,which accounts for the categories of the strength surface,equation of state(EOS),strain rate effect,and damage.The calibrated parameters are verified through numerical tests that correspond to the experimental loading conditions.Consistency between numerical results and experimental data indicates the precision and reliability of the calibrated parameters.The methodology presented in this study is scientifically sound,straightforward,and essential for improving the TSID model.Furthermore,it has the potential to contribute to other rock constitutive models,particularly new user-defined models. 展开更多
关键词 Damage constitutive model Parameter calibration Rock modeling SANDSTone Dynamic impact load Tensile-shear interactive damage(TSID)model
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Mechanical behavior and damage constitutive model of sandstone under hydro-mechanical (H-M) coupling
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作者 Tao Tan Chunyang Zhang +1 位作者 Yanlin Zhao Xiaoshuang Li 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2024年第6期837-853,共17页
Underground engineering often passes through water-rich fractured rock masses, which are prone to fracture and instability under the long-term coupling of in-situ stress field and pore water(P-W) pressure, ultimately ... Underground engineering often passes through water-rich fractured rock masses, which are prone to fracture and instability under the long-term coupling of in-situ stress field and pore water(P-W) pressure, ultimately threatening the stability of underground structures. In order to explore the mechanical properties of rocks under H-M coupling, the corresponding damage constitutive(D-C) model has become the focus of attention. Considering the inadequacy of the current research on rock strength parameters,energy evolution characteristics and D-C model under H-M coupling, the mechanical properties of typical sandstone samples are discussed based on laboratory tests. The results show that the variation of characteristic stresses of sandstone under H-M coupling conforms to the normalized attenuation equation and Mohr-Coulomb(M-C) criterion. The P-W pressure mechanism of sandstone exhibits a dynamic change from softening effect to H-M fracturing effect. The closure stress is mainly provided by cohesive strength, while the initiation stress, damage stress, and peak stress are jointly dominated by cohesive strength and friction strength. In addition, residual stress is attributed to the friction strength formed by the bite of the fracture surface. Subsequently, the energy evolution characteristics of sandstone under H-M coupling were studied, and it was found that P-W pressure weakened the energy storage capacity and energy dissipation capacity of sandstone, and H-M fracturing was an important factor in reducing its energy storage efficiency. Finally, combined with energy dissipation theory and statistical damage theory, two types of D-C models considering P-W pressure are proposed accordingly, and the model parameters can be determined by four methods. The application results indicate that the proposed and modified D-C models have high reliability, and can characterize the mechanical behavior of sandstone under H-M coupling, overcome the inconvenience of existing D-C models due to excessive mechanical parameters,and can be applied to the full-range stress–strain process. The results are conducive to revealing the deformation and damage mechanisms of rocks under H-M coupling, and can provide theoretical guidance for related engineering problems. 展开更多
关键词 H-M coupling Water-saturated sandstone Mechanical mechanism Energy evolution D-C model
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Multi-scenario Simulation and Spatial-temporal Analysis of LUCC in China's Coastal Zone Based on Coupled SD-FLUS Model
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作者 HOU Xiyong SONG Baiyuan +2 位作者 ZHANG Xueying WANG Xiaoli LI Dong 《Chinese Geographical Science》 SCIE CSCD 2024年第4期579-598,共20页
Increased human activities in China's coastal zone have resulted in the depletion of ecological land resources.Thus,conducting current and future multi-scenario simulation research on land use and land cover chang... Increased human activities in China's coastal zone have resulted in the depletion of ecological land resources.Thus,conducting current and future multi-scenario simulation research on land use and land cover change(LUCC)is crucial for guiding the healthy and sustainable development of coastal zones.System dynamic(SD)-future land use simulation(FLUS)model,a coupled simulation model,was developed to analyze land use dynamics in China's coastal zone.This model encompasses five scenarios,namely,SSP1-RCP2.6(A),SSP2-RCP4.5(B),SSP3-RCP4.5(C),SSP4-RCP4.5(D),and SSP5-RCP8.5(E).The SD model simulates land use demand on an annual basis up to the year 2100.Subsequently,the FLUS model determines the spatial distribution of land use for the near term(2035),medium term(2050),and long term(2100).Results reveal a slowing trend in land use changes in China's coastal zone from 2000–2020.Among these changes,the expansion rate of construction land was the highest and exhibited an annual decrease.By 2100,land use predictions exhibit high accuracy,and notable differences are observed in trends across scenarios.In summary,the expansion of production,living,and ecological spaces toward the sea remains prominent.Scenario A emphasizes reduced land resource dependence,benefiting ecological land protection.Scenario B witnesses an intensified expansion of artificial wetlands.Scenario C sees substantial land needs for living and production,while Scenario D shows coastal forest and grassland shrinkage.Lastly,in Scenario E,the conflict between humans and land intensifies.This study presents pertinent recommendations for the future development,utilization,and management of coastal areas in China.The research contributes valuable scientific support for informed,long-term strategic decision making within coastal regions. 展开更多
关键词 land use and land cover change(LUCC) multi-scenario simulation system dynamic-future land use simulation(SD-FLUS)model SSP-RCP scenarios model coupling China's coastal zone
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A whole process damage constitutive model for layered sandstone under uniaxial compression based on Logistic function
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作者 LIU Dong-qiao GUO Yun-peng +1 位作者 LING Kai LI Jie-yu 《Journal of Central South University》 SCIE EI CAS CSCD 2024年第7期2411-2430,共20页
Bedding structural planes significantly influence the mechanical properties and stability of engineering rock masses.This study conducts uniaxial compression tests on layered sandstone with various bedding angles(0... Bedding structural planes significantly influence the mechanical properties and stability of engineering rock masses.This study conducts uniaxial compression tests on layered sandstone with various bedding angles(0°,15°,30°,45°,60°,75°and 90°)to explore the impact of bedding angle on the deformational mechanical response,failure mode,and damage evolution processes of rocks.It develops a damage model based on the Logistic equation derived from the modulus’s degradation considering the combined effect of the sandstone bedding dip angle and load.This model is employed to study the damage accumulation state and its evolution within the layered rock mass.This research also introduces a piecewise constitutive model that considers the initial compaction characteristics to simulate the whole deformation process of layered sandstone under uniaxial compression.The results revealed that as the bedding angle increases from 0°to 90°,the uniaxial compressive strength and elastic modulus of layered sandstone significantly decrease,slightly increase,and then decline again.The corresponding failure modes transition from splitting tensile failure to slipping shear failure and back to splitting tensile failure.As indicated by the modulus’s degradation,the damage characteristics can be categorized into four stages:initial no damage,damage initiation,damage acceleration,and damage deceleration termination.The theoretical damage model based on the Logistic equation effectively simulates and predicts the entire damage evolution process.Moreover,the theoretical constitutive model curves closely align with the actual stress−strain curves of layered sandstone under uniaxial compression.The introduced constitutive model is concise,with fewer parameters,a straightforward parameter determination process,and a clear physical interpretation.This study offers valuable insights into the theory of layered rock mechanics and holds implications for ensuring the safety of rock engineering. 展开更多
关键词 layered sandstone uniaxial compression damage evolution Logistic function constitutive model
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An agent-based model of agricultural land expansion in the mountain forest of Timor Island,Indonesia
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作者 PUJIONO Eko SADONO Ronggo +12 位作者 IMRON Muhammad Ali SUTOMO JANUAR Hedi Indra KUSWANDI Relawan KURNIAWAN Hery HADI Etik Erna Wati SAPUTRA Muhammad Hadi HIDAYAH Izhamil HUMAIDA Nida SUKMAWATI Jalma Giring HADIYAN Yayan NUGROHO Agung Wahyu HANI Aditya 《Journal of Mountain Science》 SCIE CSCD 2024年第7期2263-2282,共20页
The Mutis-Timau Forest Complex,located on Timor Island,Indonesia,is a mountainous tropical forest area that gradually decreases due to deforestation and forest degradation.Previous modelling studies based on patterns ... The Mutis-Timau Forest Complex,located on Timor Island,Indonesia,is a mountainous tropical forest area that gradually decreases due to deforestation and forest degradation.Previous modelling studies based on patterns indicate that deforestation primarily occurs at lower elevations and near the boundaries of forests and settlements,often associated with shifting cultivation by local farmers.This study adopts a process-based modelling approach,specifically the agent-based model,to simulate land changes,particularly farmers'expansion of agricultural land around the Mutis mountain forest.The underlying concept of this agent-based approach is the interaction between the human and environmental systems.Farmers,representing the human system,interact with the land,which represents the environmental system,through land use decision-making mechanisms.The research was conducted in the Community Forest of the Timor Tengah Utara District,one of the sites within the Mutis-Timau Forest Complex with the highest deforestation rate.Land use change simulations were performed using agent-based modelling from 1999 to 2030,considering the socio-economic conditions of farmers,spatial preferences,land use decisions,and natural transitions.The results revealed that the agricultural area increased by 14%under the Business as Usual scenario and 5%under the Reducing Emission from Deforestation and Forest Degradation scenario,compared to the initial agricultural area of 245 hectares.The probability of farmers deciding to extend agricultural activities was positively associated with the number of livestock maintained by farmers and the size of the village area.Conversely,the likelihood of farmers opting for agricultural extensification decreased with an increase in the area of private land and the farmer's age.These findings are crucial for the managers of the Mutis-Timau Forest Complex and other relevant stakeholders,as they aid in arranging actions to combat deforestation,designing proper forest-related policies,and providing support for initiatives such as reducing emissions from deforestation and forest degradation programs or further incentive schemes. 展开更多
关键词 Agricultural land expansion Simulation Agent-based model FARMER DEFORESTATION Mountainous tropical forest
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Calculation and prediction of divertor detachment via impurity seeding by using one-dimensional model
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作者 周文杰 刘晓菊 +5 位作者 邬潇河 李邦 石奇奇 樊皓尘 杨艳杰 李国强 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第8期370-379,共10页
Achieving the detachment of divertor can help to alleviate excessive heat load and sputtering problems on the target plates,thereby extending the lifetime of divertor components for fusion devices.In order to provide ... Achieving the detachment of divertor can help to alleviate excessive heat load and sputtering problems on the target plates,thereby extending the lifetime of divertor components for fusion devices.In order to provide a fast but relatively reliable prediction of plasma parameters along the flux tube for future device design,a one-dimensional(1D)modeling code for the operating point of impurity seeded detached divertor is developed based on Python language,which is a fluid model based on previous work(Plasma Phys.Control.Fusion 58045013(2016)).The experimental observation of the onset of divertor detachment by neon(Ne)and argon(Ar)seeding in EAST is well reproduced by using the 1D modeling code.The comparison between the 1D modeling and two-dimensional(2D)simulation by the SOLPS-ITER code for CFETR detachment operation with Ne and Ar seeding also shows that they are in good agreement.We also predict the radiative power loss and corresponding impurity concentration requirement for achieving divertor detachment via different impurity seeding under high heating power conditions in EAST and CFETR phase II by using the 1D model.Based on the predictions,the optimized parameter space for divertor detachment operation on EAST and CFETR is also determined.Such a simple but reliable 1D model can provide a reasonable parameter input for a detailed and accurate analysis by 2D or three-dimensional(3D)modeling tools through rapid parameter scanning. 展开更多
关键词 divertor detachment impurity seeding one-dimensional modeling
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Thermal-contact capacity of one-dimensional attractive Gaudin-Yang model
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作者 张小敏 程颂 陈洋洋 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第4期231-235,共5页
Tan's contact C is an important quantity measuring the two-body correlations at short distances in a dilute system.Here we make use of the technique of exactly solved models to study the thermal-contact capacity K... Tan's contact C is an important quantity measuring the two-body correlations at short distances in a dilute system.Here we make use of the technique of exactly solved models to study the thermal-contact capacity K_(T),i.e.,the derivative of C with respect to temperature in the attractive Gaudin-Yang model.It is found that K_(T) is useful in identifying the low temperature phase diagram,and using the obtained analytical expression of K_(T),we study its critical behavior and the scaling law.Especially,we show K_(T) versus temperature and thus the non-monotonic tendency of C in a tiny interval,for both spin-balanced and imbalanced phases.Such a phenomenon is merely observed in multi-component systems such as SU(2)Fermi gases and spinor bosons,indicating the crossover from the Tomonaga-Luttinger liquid to the spin-coherent liquid. 展开更多
关键词 Tan's Contact Gaudin-Yang model Bethe ansatz
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Investigation of Maxima Assumptions in Modelling Tropical Cyclone- Induced Hazards in the South China Sea
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作者 WEN Ze-guo WANG Fu-ming +1 位作者 WAN Jing YANG Fan 《China Ocean Engineering》 SCIE EI CSCD 2024年第3期491-504,共14页
The present study aims to examine the suitability of two commonly used assumptions that simplify modelling metoceanconditions for designing offshore wind turbines in the South China Sea (SCS). The first assumption ass... The present study aims to examine the suitability of two commonly used assumptions that simplify modelling metoceanconditions for designing offshore wind turbines in the South China Sea (SCS). The first assumption assumes thatjoint N-year extreme wind and wave events can be independently estimated and subsequently combined. The secondone assumes peak wind and waves can be modelled as occurring simultaneously during a tropical cyclone (TC) event.To better understand the potential TC activity, a set of 10000 years synthetic TC events are generated. The wind fieldmodel and the Mike 21 spectral wave model are employed to model the TC-induced hazards. Subsequently, theeffect of the assumptions is evaluated by analyzing the peak structural response of both monopile and semisubmersibleoffshore wind turbines during TC events. The results demonstrate that the examined assumptions are generally accurate.By assessing the implications of these assumptions, valuable insights are obtained, which can inform andimprove the modelling of TC-induced hazards in the SCS region. 展开更多
关键词 tropical cyclone numerical wave modelling hazards offshore wind turbines structural response
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Locally and globally uniform approximations for ruin probabilities of a nonstandard bidimensional risk model with subexponential claims
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作者 LIU Zai-ming GENG Bing-zhen WANG Shi-jie 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 2024年第1期98-113,共16页
Consider a nonstandard continuous-time bidimensional risk model with constant force of interest,in which the two classes of claims with subexponential distributions satisfy a general dependence structure and each pair... Consider a nonstandard continuous-time bidimensional risk model with constant force of interest,in which the two classes of claims with subexponential distributions satisfy a general dependence structure and each pair of the claim-inter-arrival times is arbitrarily dependent.Under some mild conditions,we achieve a locally uniform approximation of the finite-time ruin probability for all time horizon within a finite interval.If we further assume that each pair of the claim-inter-arrival times is negative quadrant dependent and the two classes of claims are consistently-varying-tailed,it shows that the above obtained approximation is also globally uniform for all time horizon within an infinite interval. 展开更多
关键词 bidimensional risk model asymptotic formula subexponential distribution consistently varying tail ruin probability
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Modelling the viscoplastic behaviour of Callovo-Oxfordian claystone with consideration of damage effect
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作者 Hao Wang Yu-Jun Cui +1 位作者 Minh Ngoc Vu Jean Talandier 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第1期303-316,共14页
In order to evaluate the performance of deep geological disposal of radioactive waste,an underground research laboratory(URL)was constructed by Andra in the Callovo-Oxfordian(COx)claystone formation at the Meuse/Haute... In order to evaluate the performance of deep geological disposal of radioactive waste,an underground research laboratory(URL)was constructed by Andra in the Callovo-Oxfordian(COx)claystone formation at the Meuse/Haute-Marne(MHM).The construction of URL induced the excavation damage of host formations,and the ventilation in the galleries desaturated the host formation close to the gallery wall.Moreover,it is expected that the mechanical behaviour of COx claystone is time-dependent.This study presents a constitutive model developed to describe the viscoplastic behaviour of unsaturated and damaged COx claystone.In this model,the unsaturation effect is considered by adopting the Bishop effective stress and the van Genuchten(VG)water retention model.In terms of the viscoplastic behaviour,the nonstationary flow surface(NSFS)theory for unsaturated soils is used with consideration of the coupled effects of strain rate and suction on the yield stress.A progressive hardening law is adopted.Meanwhile,a non-associated flow rule is used,which is similar to that in Barcelona basic model(BBM).In addition,to describe the damage effect induced by suction change and viscoplastic loading,a damage function is defined based on the crack volume proportion.This damage function contains two variables:unsaturated effective stress and viscoplastic volumetric strain,with the related parameters determined based on the mercury intrusion porosimetry(MIP)tests.For the model validation,different tests on COx claystone under different loading paths are simulated.Comparisons between experimental and simulated results indicated that the present model is able to well describe the viscoplastic behaviour of damaged COx claystone,including swelling/shrinkage,triaxial extension and compression,and triaxial creep. 展开更多
关键词 Callovo-Oxfordian(COx)claystone Excavation damage Time-dependent behaviour SUCTION Viscoplastic model
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Investigation of FRP and SFRC Technologies for Efficient Tunnel Reinforcement Using the Cohesive Zone Model
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作者 Gang Niu Zhaoyang Jin +1 位作者 Wei Zhang Yiqun Huang 《Structural Durability & Health Monitoring》 EI 2024年第2期161-179,共19页
Amid urbanization and the continuous expansion of transportation networks,the necessity for tunnel construction and maintenance has become paramount.Addressing this need requires the investigation of efficient,economi... Amid urbanization and the continuous expansion of transportation networks,the necessity for tunnel construction and maintenance has become paramount.Addressing this need requires the investigation of efficient,economical,and robust tunnel reinforcement techniques.This paper explores fiber reinforced polymer(FRP)and steel fiber reinforced concrete(SFRC)technologies,which have emerged as viable solutions for enhancing tunnel structures.FRP is celebrated for its lightweight and high-strength attributes,effectively augmenting load-bearing capacity and seismic resistance,while SFRC’s notable crack resistance and longevity potentially enhance the performance of tunnel segments.Nonetheless,current research predominantly focuses on experimental analysis,lacking comprehensive theoretical models.To bridge this gap,the cohesive zone model(CZM),which utilizes cohesive elements to characterize the potential fracture surfaces of concrete/SFRC,the rebar-concrete interface,and the FRP-concrete interface,was employed.A modeling approach was subsequently proposed to construct a tunnel segment model reinforced with either SFRC or FRP.Moreover,the corresponding mixed-mode constitutive models,considering interfacial friction,were integrated into the proposed model.Experimental validation and numerical simulations corroborated the accuracy of the proposed model.Additionally,this study examined the reinforcement design of tunnel segments.Through a numerical evaluation,the effectiveness of innovative reinforcement schemes,such as substituting concrete with SFRC and externally bonding FRP sheets,was assessed utilizing a case study from the Fuzhou Metro Shield Tunnel Construction Project. 展开更多
关键词 Tunnel segment FRP SFRC cohesive zone model constitutive model fracture process
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Evaluation of Nonbreaking Wave-Induced Mixing Parameterization Schemes Based on a One-Dimensional Ocean Model
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作者 TANG Ran HUANG Chuanjiang +1 位作者 DAI Dejun WANG Gang 《Journal of Ocean University of China》 SCIE CAS CSCD 2024年第3期567-576,共10页
Surface waves have a considerable effect on vertical mixing in the upper ocean.In the past two decades,the vertical mixing induced through nonbreaking surface waves has been used in ocean and climate models to improve... Surface waves have a considerable effect on vertical mixing in the upper ocean.In the past two decades,the vertical mixing induced through nonbreaking surface waves has been used in ocean and climate models to improve the simulation of the upper ocean.Thus far,several nonbreaking wave-induced mixing parameterization schemes have been proposed;however,no quantitative comparison has been performed among them.In this paper,a one-dimensional ocean model was used to compare the performances of five schemes,including those of Qiao et al.(Q),Hu and Wang(HW),Huang and Qiao(HQ),Pleskachevsky et al.(P),and Ghantous and Babanin(GB).Similar to previous studies,all of these schemes can decrease the simulated sea surface temperature(SST),increase the subsurface temperature,and deepen the mixed layer,thereby alleviating the common thermal deviation problem of the ocean model for upper ocean simulation.Among these schemes,the HQ scheme exhibited the weakest wave-induced mixing effect,and the HW scheme exhibited the strongest effect;the other three schemes exhibited roughly the same effect.In particular,the Q and P schemes exhibited nearly the same effect.In the simulation based on observations from the Ocean Weather Station Papa,the HQ scheme exhibited the best performance,followed by the Q scheme.In the experiment with the HQ scheme,the root-mean-square deviation of the simulated SST from the observations was 0.43℃,and the mixed layer depth(MLD)was 2.0 m.As a contrast,the deviations of the SST and MLD reached 1.25℃ and 8.4 m,respectively,in the experiment without wave-induced mixing. 展开更多
关键词 wave-induced mixing surface waves sea surface temperature mixed layer depth General Ocean Turbulence model
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Bayesian network-based survival prediction model for patients having undergone post-transjugular intrahepatic portosystemic shunt for portal hypertension
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作者 Rong Chen Ling Luo +3 位作者 Yun-Zhi Zhang Zhen Liu An-Lin Liu Yi-Wen Zhang 《World Journal of Gastroenterology》 SCIE CAS 2024年第13期1859-1870,共12页
BACKGROUND Portal hypertension(PHT),primarily induced by cirrhosis,manifests severe symptoms impacting patient survival.Although transjugular intrahepatic portosystemic shunt(TIPS)is a critical intervention for managi... BACKGROUND Portal hypertension(PHT),primarily induced by cirrhosis,manifests severe symptoms impacting patient survival.Although transjugular intrahepatic portosystemic shunt(TIPS)is a critical intervention for managing PHT,it carries risks like hepatic encephalopathy,thus affecting patient survival prognosis.To our knowledge,existing prognostic models for post-TIPS survival in patients with PHT fail to account for the interplay among and collective impact of various prognostic factors on outcomes.Consequently,the development of an innovative modeling approach is essential to address this limitation.AIM To develop and validate a Bayesian network(BN)-based survival prediction model for patients with cirrhosis-induced PHT having undergone TIPS.METHODS The clinical data of 393 patients with cirrhosis-induced PHT who underwent TIPS surgery at the Second Affiliated Hospital of Chongqing Medical University between January 2015 and May 2022 were retrospectively analyzed.Variables were selected using Cox and least absolute shrinkage and selection operator regression methods,and a BN-based model was established and evaluated to predict survival in patients having undergone TIPS surgery for PHT.RESULTS Variable selection revealed the following as key factors impacting survival:age,ascites,hypertension,indications for TIPS,postoperative portal vein pressure(post-PVP),aspartate aminotransferase,alkaline phosphatase,total bilirubin,prealbumin,the Child-Pugh grade,and the model for end-stage liver disease(MELD)score.Based on the above-mentioned variables,a BN-based 2-year survival prognostic prediction model was constructed,which identified the following factors to be directly linked to the survival time:age,ascites,indications for TIPS,concurrent hypertension,post-PVP,the Child-Pugh grade,and the MELD score.The Bayesian information criterion was 3589.04,and 10-fold cross-validation indicated an average log-likelihood loss of 5.55 with a standard deviation of 0.16.The model’s accuracy,precision,recall,and F1 score were 0.90,0.92,0.97,and 0.95 respectively,with the area under the receiver operating characteristic curve being 0.72.CONCLUSION This study successfully developed a BN-based survival prediction model with good predictive capabilities.It offers valuable insights for treatment strategies and prognostic evaluations in patients having undergone TIPS surgery for PHT. 展开更多
关键词 Bayesian network CIRRHOSIS Portal hypertension Transjugular intrahepatic portosystemic shunt Survival prediction model
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The bio-active components of the Mongolian medicine Horcha-6 and therapeutic mechanism in the rat migraine model
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作者 Ao Qier Naren Mandula +7 位作者 Qiburi Qiburi Manda Manda Tegexi Baiyin Xilinqiqige Bao Huricha Baigued Chang-Shan Wang Temuqile Temuqile De-Zhi Yang 《Traditional Medicine Research》 2024年第2期8-17,共10页
Background:The active components of Horcha-6 were identified using liquid chromatography with tandem mass spectrometry.Also,we investigated the potential mechanisms that explain why Horcha-6 may be effective in treati... Background:The active components of Horcha-6 were identified using liquid chromatography with tandem mass spectrometry.Also,we investigated the potential mechanisms that explain why Horcha-6 may be effective in treating migraines through the use of network pharmacology and a rat migraine model.Methods:After identifying the active components of Horcha-6,the corresponding genes of the active components’target were obtained from the Universal Protein database,and a“compound-target-disease”network was constructed using Cytoscape 3.9.0 software.For the in vivo experiments,nitroglycerin was injected intraperitoneally into rats to create a migraine model.Pre-treatment with Horcha-6 was administered orally for 14 days,and rats were subjected to migraine-related behavior tests.RNA sequencing was performed to identify the gene expression regulated by Horcha-6 in the trigeminal nerve.Results:A total of 903 chemical components of Horcha-6 have been collected in the liquid chromatography with tandem mass spectrometry.We discovered 55 of the Horcha-6 bio-active components that were evaluated based on their Percent Human Oral Absorption(≥30%)and DL values(≥0.185)on the traditional Chinese medicine systems pharmacology database.The“compound-target-disease”network contained 163 intersection targets with the migraine state.Gene Ontology analysis indicated that these components significantly regulated the immune response,vascular function,oxidative stress,etc.When Kyoto Encyclopedia of Genes and Genomes enrichment analysis was performed,we observed that most of the target genes were significantly enriched in the inflammation and neuro-related signaling pathway,toll-like receptor signaling pathway,neuroactive ligand-receptor interaction,etc.These predictions were further demonstrated via in vivo animal model experiments.The RNA sequencing results showed that 41 genes were down-regulated(P<0.05)and 86 genes were up-regulated(P<0.05)in the Horcha-6 treated group compared with the untreated group.Those genes were mainly involved in neuromodulation,vascular function,and hormone metabolism.Conclusion:The 55 bio-active components in Horcha-6 regulate inflammation,hormone metabolism,and neurotransmitters and have potential as a therapy to treat migraines. 展开更多
关键词 Horcha-6 bio-active components rat migraine model inflammation hormone metabolism NEUROTRANSMITTER
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Metal-N_(4)model single‐atom catalyst with electroneutral quadri‐pyridine macrocyclic ligand for CO_(2)electroreduction
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作者 Jian‐Zhao Peng Yin‐Long Li +7 位作者 Yao‐Ti Cheng Fu‐Zhi Li Bo Cao Qing Wang Xian Yue Guo‐Tao Lai Yang‐Gang Wang Jun Gu 《Carbon Energy》 SCIE EI CAS CSCD 2024年第8期122-133,共12页
Metal–N–C single‐atom catalysts,mostly prepared from pyrolysis of metalorganic precursors,are widely used in heterogeneous electrocatalysis.Since metal sites with diverse local structures coexist in this type of ma... Metal–N–C single‐atom catalysts,mostly prepared from pyrolysis of metalorganic precursors,are widely used in heterogeneous electrocatalysis.Since metal sites with diverse local structures coexist in this type of material and it is challenging to characterize the local structure,a reliable structure–property relationship is difficult to establish.Conjugated macrocyclic complexes adsorbed on carbon support are well‐defined models to mimic the singleatom catalysts.Metal–N_(4)site with four electroneutral pyridine‐type ligands embedded in a graphene layer is the most commonly proposed structure of the active site of single‐atom catalysts,but its molecular counterpart has not been reported.In this work,we synthesized the conjugated macrocyclic complexes with a metal center(Co,Fe,or Ni)coordinated with four electroneutral pyridinic ligands as model catalysts for CO_(2)electroreduction.For comparison,the complexes with anionic quadri‐pyridine macrocyclic ligand were also prepared.The Co complex with the electroneutral ligand expressed a turnover frequency of CO formation more than an order of magnitude higher than that of the Co complex with the anionic ligand.Constrained ab initio molecular dynamics simulations based on the well‐defined structures of the model catalysts indicate that the Co complex with the electroneutral ligand possesses a stronger ability to mediate electron transfer from carbon to CO_(2). 展开更多
关键词 ab initio molecular dynamics CO_(2)reduction electrocatalysis model catalyst single‐atom catalyst
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Effect of dry-wet cycles on dynamic properties and microstructures of sandstone:Experiments and modelling
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作者 Hai Pu Qingyu Yi +3 位作者 Andrey P.Jivkov Zhengfu Bian Weiqiang Chen Jiangyu Wu 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2024年第5期655-679,共25页
Underground pumped storage power plant(UPSP)is an innovative concept for space recycling of abandoned mines.Its realization requires better understanding of the dynamic performance and durability of reservoir rock.Thi... Underground pumped storage power plant(UPSP)is an innovative concept for space recycling of abandoned mines.Its realization requires better understanding of the dynamic performance and durability of reservoir rock.This paper conducted ultrasonic detection,split Hopkinson pressure bar(SHPB)impact,mercury intrusion porosimetry(MIP),and backscatter electron observation(BSE)tests to investigate the dynamical behaviour and microstructure of sandstone with cyclical dry-wet damage.A coupling FEM-DEM model was constructed for reappearing mesoscopic structure damage.The results show that dry-wet cycles decrease the dynamic compressive strength(DCS)with a maximum reduction of 39.40%,the elastic limit strength is reduced from 41.75 to 25.62 MPa.The sieved fragments obtain the highest crack growth rate during the 23rd dry-wet cycle with a predictable life of 25 cycles for each rock particle.The pore fractal features of the macropores and micro-meso pores show great differences between the early and late cycles,which verifies the computational statistics analysis of particle deterioration.The numerical results show that the failure patterns are governed by the strain in pre-peak stage and the shear cracks are dominant.The dry-wet cycles reduce the energy transfer efficiency and lead to the discretization of force chain and crack fields. 展开更多
关键词 Underground pumped storage power plant Dry-wet cycles Split Hopkinson pressure bar Macro and micro properties FEM-DEM coupling model Damage characterization
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Numerical Analysis of Fiber Reinforced Polymer-Confined Concrete under Cyclic Compression Using Cohesive Zone Models
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作者 Mingxu Zhang Mingliang Wang Wei Zhang 《Structural Durability & Health Monitoring》 EI 2024年第5期599-622,共24页
This paper examines the mechanical behavior offiber reinforced polymer(FRP)-confined concrete under cyclic compression using the 3D cohesive zone model(CZM).A numerical modeling method was developed,employing zero-thick... This paper examines the mechanical behavior offiber reinforced polymer(FRP)-confined concrete under cyclic compression using the 3D cohesive zone model(CZM).A numerical modeling method was developed,employing zero-thickness cohesive elements to represent the stress-displacement relationship of concrete potential fracture surfaces and FRP-concrete interfaces.Additionally,mixed-mode damage plastic constitutive models were pro-posed for the concrete potential fracture surfaces and FRP-concrete interface,considering interfacial friction.Furthermore,an anisotropic plastic constitutive model was developed for the FRP composite jacket.The CZM model proposed in this study was validated using experimental data from plain concrete and large rupture strain(LRS)FRP-confined concrete subjected to cyclic compression.The simulation results demonstrate that the pro-posed model accurately predicts the mechanical response of both concrete and FRP-confined concrete under cyc-lic compression.Lastly,various parametric studies were conducted to investigate the internal failure mechanism of FRP-confined concrete under cyclic loading to analyze the influence of the inner friction plasticity of different components. 展开更多
关键词 Cyclic compression CZM FRP wrapped concrete constitutive model fracture behavior
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Effect of information-motivation-behavioral skills model based perioperative nursing on pain in patients with gallstones
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作者 Li Ma Ying Yu +2 位作者 Bin-Juan Zhao Yan-Nan Yu Yu Li 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第7期2232-2241,共10页
BACKGROUND The incidence of cholecystolithiasis is on the rise.Use of information,motivation,and behavioral skills can play a positive role in promoting changes in individual health behaviors.However,reports on the ef... BACKGROUND The incidence of cholecystolithiasis is on the rise.Use of information,motivation,and behavioral skills can play a positive role in promoting changes in individual health behaviors.However,reports on the effects of information-motivationbehavioral(IMB)skills model based high-quality nursing as a perioperative nursing intervention for patients with gallstones are nonexistent.AIM To explore the application of IMB skills model based high-quality nursing in patients with gallstones.METHODS Two hundred and sixteen patients with cholecystolithiasis treated at our hospital from January 2022 to January 2023 were enrolled and divided into a control,highquality,and combined nursing groups,with 72 patients in each group.The control,high-quality,and combination groups received conventional,high-quality,and IMB skills model based perioperative nursing services,respectively.Differences in clinical indicators,stress levels,degree of pain,emotional state,and quality of life were observed,and complications and nursing satisfaction among the three groups were evaluated.RESULTS After nursing,the time to recovery of gastrointestinal function in the high-quality and combined nursing groups was significantly shorter than that of the control group,with the recovery of gastrointestinal function being the fastest in the combined nursing group(P<0.05).After nursing intervention,cortisol and norepinephrine levels in the high-quality and combined nursing groups were closer to normal than those of the control group 24 h after surgery,with the combined nursing group having the closest to normal levels(P<0.05).After 3 and 7 d of intervention,the patients’pain significantly improved,which was more prominent in the highquality and combination groups.Meanwhile,the pain score in the combination group was significantly lower than those of the control and high-quality nursing groups(P<0.05).After nursing intervention,the emotional states of all patients improved,and the scores of patients in the combination group were significantly lower than those of the control and high-quality nursing groups.The quality of life of patients in the high-quality and combined nursing groups significantly improved after nursing intervention compared to that of the control group,with the combined nursing group having the highest quality of life score.After intervention,the incidence of complications in the high-quality and combination groups was significantly lower than that of the control group(P<0.05),but the difference between the combination and high-quality nursing groups was not significant.Nursing satisfaction of patients in the high-quality and combination groups was significantly higher than that of the control group,with the nursing satisfaction being the highest in the combination group(P<0.05).CONCLUSION IMB skills model based nursing can improve surgical stress levels,degrees of pain,emotional state,quality of life,and nursing satisfaction of patients with gallstones and reduce the incidence of complications. 展开更多
关键词 Biliary calculi Information-motivation-behavioral skills model High quality care Perioperative period PAIN Application
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