In this paper,the homotopy analysis method (HAM) is applied to solve generalized biological populationmodels.The fractional derivatives are described by Caputo's sense.The method introduces a significant improveme...In this paper,the homotopy analysis method (HAM) is applied to solve generalized biological populationmodels.The fractional derivatives are described by Caputo's sense.The method introduces a significant improvementin this field over existing techniques.Results obtained using the scheme presented here agree well with the analyticalsolutions and the numerical results presented in Ref.[6].However,the fundamental solutions of these equations stillexhibit useful scaling properties that make them attractive for applications.展开更多
Background:One of the most challenging tasks in wildlife conservation and management is clarifying which and how external and intrinsic factors influence wildlife demography and long-term viability.The wild population...Background:One of the most challenging tasks in wildlife conservation and management is clarifying which and how external and intrinsic factors influence wildlife demography and long-term viability.The wild population of the Crested Ibis(Nipponia nippon)has recovered to approximately 4400,and several reintroduction programs have been carried out in China,Japan and Korea.Population viability analysis on this endangered species has been limited to the wild population,showing that the long-term population growth is restricted by the carrying capacity and inbreeding.However,gaps in knowledge of the viability of the reintroduced population and its drivers in the release environment impede the identification of the most effective population-level priorities for aiding in species recovery.Methods:The field monitoring data were collected from a reintroduced Crested Ibis population in Ningshan,China from 2007 to 2018.An individual-based VORTEX model(Version 10.3.5.0)was used to predict the future viability of the reintroduced population by incorporating adaptive patterns of ibis movement in relation to catastrophe frequency,mortality and sex ratio.Results:The reintroduced population in Ningshan County is unlikely to go extinct in the next 50 years.The popula-tion size was estimated to be 367,and the population genetic diversity was estimated to be 0.97.Sensitivity analysis showed that population size and extinction probability were dependent on the carrying capacity and sex ratio.The carrying capacity is the main factor accounting for the population size and genetic diversity,while the sex ratio is the primary factor responsible for the population growth trend.Conclusions:A viable population of the Crested Ibis can be established according to population viability analysis.Based on our results,conservation management should prioritize a balanced sex ratio,high-quality habitat and low mortality.展开更多
Three analytic algorithms based on Adomian decomposition, homotopy perturbation and homotopy analysis methods are proposed to solve some models of nonlinear age-structured population dynamics and epidemiology. Truncat...Three analytic algorithms based on Adomian decomposition, homotopy perturbation and homotopy analysis methods are proposed to solve some models of nonlinear age-structured population dynamics and epidemiology. Truncating the resulting convergent infinite series, we obtain numerical solutions of high accuracy for these models. Three numerical examples are given to illustrate the simplicity and accuracy of the methods.展开更多
Advanced digestive tract malignant tumors,represented by advanced colorectal cancer,advanced gastric cancer and advanced esophageal cancer,have insidious onsets and high mortality.Western medicine based on targeted th...Advanced digestive tract malignant tumors,represented by advanced colorectal cancer,advanced gastric cancer and advanced esophageal cancer,have insidious onsets and high mortality.Western medicine based on targeted therapy greatly can improves the benefit and efficacy for patients through population stratification,but its population is limited.Traditional Chinese medicine(TCM)has a long history in treatment of tumors,which is an important part of comprehensive treatment of tumors.Clinical observation has shown that different patients could get different efficacy from TCM treatment.Based on real world registration studies,patients with advanced colorectal cancer,advanced gastric cancer or advanced esophageal cancer who had received TCM treatment were observed and followed,and a TCM dominant population that achieved significant efficacy was screened out to carry out multivariate regression analysis,further explore key factors that affect survival in advanced digestive tract malignant tumors,and establish a prediction model of TCM dominant population.It will provide reference for the follow-up TCM treatment,and provide reference for development of individualized treatment plans,making the TCM treatment for advanced digestive tract malignant tumors more targeted,and helping to improve the benefit rate in TCM.展开更多
In order to estimate the most effect stage and process on population growth and effective conserve the rare endangered plant Davidia involucrata, we analyzed the dynamics and the contributions of life-history componen...In order to estimate the most effect stage and process on population growth and effective conserve the rare endangered plant Davidia involucrata, we analyzed the dynamics and the contributions of life-history components on population dynamics based on Lefkovitch matrix model and sensitivity analysis. The life cycle of Davidia involucrata was divided into six stages (seed, seedling, juvenile, immature, early adult and late adult) based on the species characteristics and published literature data, the survival rates in each life-history stage were simulated using a static life table, and the fecundity of each stage was determined according to sample information. The results showed that the structure of the observed population was not ideal, and the numbers of seedlings and coppice shoots was similar. The population growth rate was influenced largely by individual growth process, and asexual reproduction made a larger contribution to population growth than sexual reproduction. However, sexual reproduction was more important than asexual reproduction, because most asexual reproducing individuals (the coppice shoots) were derived mainly from human destruction (e.g. felling trees). The most important stage was stage V (late adult), associated with seed production and germination. Therefore, conservation of Davidia involucrata populations should focus on stage V and sexual reproduction, in order to improve the seed production and germination rate, and to promote population stability and development.展开更多
In the past few years, genome-wide association study (GWAS) has made great successes in identifying genetic susceptibility loci underlying many complex diseases and traits. The findings provide important genetic ins...In the past few years, genome-wide association study (GWAS) has made great successes in identifying genetic susceptibility loci underlying many complex diseases and traits. The findings provide important genetic insights into understanding pathogenesis of diseases. In this paper, we present an overview of widely used approaches and strategies for analysis of GWAS, offered a general consideration to deal with GWAS data. The issues regarding data quality control, population structure, association analysis, multiple comparison and visual presentation of GWAS results are discussed; other advanced topics including the issue of missing heritability, meta-analysis, setbased association analysis, copy number variation analysis and GWAS cohort analysis are also briefly introduced.展开更多
In recent years, population growth models with spatial diffusion have beenextensively studied by many authors (for example, see [1-5]). In this paper, a populationgrowth model is considered with a discrete age-depende...In recent years, population growth models with spatial diffusion have beenextensively studied by many authors (for example, see [1-5]). In this paper, a populationgrowth model is considered with a discrete age-dependence and spatial diffusion, and isinvestigated in a semigroup framework. The spectral properties of the population oper-ator are given. On the basis of such spectral consideration, the asymptotic behaviourof the semigroup generated by the population operator is obtained. Finally, a nonlinearpopulation growth model is considered and its stability is analyzed.展开更多
In this paper, a non-smooth population model with impulsive effects is proposed by combining discontinuity and non-smoothness. According to the qualitative theory of differential equations, the global analysis of the ...In this paper, a non-smooth population model with impulsive effects is proposed by combining discontinuity and non-smoothness. According to the qualitative theory of differential equations, the global analysis of the model is discussed. Using the theory of impulsive differential equations, the existence conditions of order one periodic solution are obtained. And the impulsive controllers are designed to make the pest populations stay at the refuge level. Some simulations are carried out to prove the results.展开更多
为了弥补一次性建模分析的缺陷,提高小麦条锈病遥感监测模型的运行效率和精度,根据模型集群分析(Model population analysis,MPA)算法的特点,综合利用光谱区间选择算法和光谱点选择算法的优势,提出了一种联合相关系数(Correlation coeff...为了弥补一次性建模分析的缺陷,提高小麦条锈病遥感监测模型的运行效率和精度,根据模型集群分析(Model population analysis,MPA)算法的特点,综合利用光谱区间选择算法和光谱点选择算法的优势,提出了一种联合相关系数(Correlation coefficient,CC)与MPA的特征变量优选算法。在利用CC算法对全波段光谱进行特征变量选择的基础上,分别利用基于MPA思想开发的竞争性自适应重加权采样法(Competitive adaptive reweighted sampling,CARS)和变量组合集群分析法(Variable combination population analysis,VCPA)进一步优选对小麦条锈病敏感的特征变量,并利用偏最小二乘回归(Partial least squares regression,PLSR)算法构建了小麦条锈病遥感监测的CC-CARS和CC-VCPA模型。结果表明:联合CC MPA算法优选的特征变量构建的CC-CARS和CC-VCPA模型精度均高于CC、CARS和VCPA算法。3组验证集样本中,CC-CARS模型预测病情指数(Disease index,DI)与实测DI间的R^(2)_(V)较CC模型和CARS模型至少分别提高了6.78%和6.66%,RMSEV至少分别降低了15.31%和10.98%,RPD至少分别提高了18.08%和12.34%。CC VCPA模型预测DI与实测DI间的R^(2)_(V)较CC模型和VCPA模型至少分别提高了9.58%和0.73%,RMSEV至少分别降低了20.78%和3.86%,RPD至少分别提高了26.22%和4.02%。基于CC-MPA的光谱特征优选算法是一种有效的特征选择方法,尤其是利用CC-VCPA方法选择的特征变量数更少,模型预测效果更好,研究结果对光谱特征优选及提高作物病害遥感监测精度具有重要的参考价值。展开更多
In this study, the mathematical models of dynamics of student populations in the university departments are formulated. As a case study, we employ the data of registration section from Department of Mathematics, Facul...In this study, the mathematical models of dynamics of student populations in the university departments are formulated. As a case study, we employ the data of registration section from Department of Mathematics, Faculty of Applied Science, King Mongkut’s University of Technology North Bangkok (KMUTNB), Thailand, from calendar year 2006 to 2010. Using regression analysis, descriptive model and explanatory model are derived. The descriptive model is linear with R2 = 0.8864. Using log-transformation, the explanatory model gives the nonlinear approximation with R2 = 0.8293. The model predicts that the number of students of Department of Mathematics, KMUTNB has a tendency to linearly increase with slope of 20 with 95% CI (6.8417, 33.1583). The application of the models in educational management is discussed.展开更多
文摘In this paper,the homotopy analysis method (HAM) is applied to solve generalized biological populationmodels.The fractional derivatives are described by Caputo's sense.The method introduces a significant improvementin this field over existing techniques.Results obtained using the scheme presented here agree well with the analyticalsolutions and the numerical results presented in Ref.[6].However,the fundamental solutions of these equations stillexhibit useful scaling properties that make them attractive for applications.
基金The study was supported by Shaanxi Forestry Bureau and National Natural Science Foundation of China(Grant Nos.31872245 and 31572282).
文摘Background:One of the most challenging tasks in wildlife conservation and management is clarifying which and how external and intrinsic factors influence wildlife demography and long-term viability.The wild population of the Crested Ibis(Nipponia nippon)has recovered to approximately 4400,and several reintroduction programs have been carried out in China,Japan and Korea.Population viability analysis on this endangered species has been limited to the wild population,showing that the long-term population growth is restricted by the carrying capacity and inbreeding.However,gaps in knowledge of the viability of the reintroduced population and its drivers in the release environment impede the identification of the most effective population-level priorities for aiding in species recovery.Methods:The field monitoring data were collected from a reintroduced Crested Ibis population in Ningshan,China from 2007 to 2018.An individual-based VORTEX model(Version 10.3.5.0)was used to predict the future viability of the reintroduced population by incorporating adaptive patterns of ibis movement in relation to catastrophe frequency,mortality and sex ratio.Results:The reintroduced population in Ningshan County is unlikely to go extinct in the next 50 years.The popula-tion size was estimated to be 367,and the population genetic diversity was estimated to be 0.97.Sensitivity analysis showed that population size and extinction probability were dependent on the carrying capacity and sex ratio.The carrying capacity is the main factor accounting for the population size and genetic diversity,while the sex ratio is the primary factor responsible for the population growth trend.Conclusions:A viable population of the Crested Ibis can be established according to population viability analysis.Based on our results,conservation management should prioritize a balanced sex ratio,high-quality habitat and low mortality.
文摘Three analytic algorithms based on Adomian decomposition, homotopy perturbation and homotopy analysis methods are proposed to solve some models of nonlinear age-structured population dynamics and epidemiology. Truncating the resulting convergent infinite series, we obtain numerical solutions of high accuracy for these models. Three numerical examples are given to illustrate the simplicity and accuracy of the methods.
基金Special Projects of Capital Scientific Research on Health Development(No.2016-1-4171)Projects on"Millions"of Talents for Inheritance and Innovation of Traditional Chinese Medicine of National Administration of Traditional Chinese Medicine(Qihuang Projects)。
文摘Advanced digestive tract malignant tumors,represented by advanced colorectal cancer,advanced gastric cancer and advanced esophageal cancer,have insidious onsets and high mortality.Western medicine based on targeted therapy greatly can improves the benefit and efficacy for patients through population stratification,but its population is limited.Traditional Chinese medicine(TCM)has a long history in treatment of tumors,which is an important part of comprehensive treatment of tumors.Clinical observation has shown that different patients could get different efficacy from TCM treatment.Based on real world registration studies,patients with advanced colorectal cancer,advanced gastric cancer or advanced esophageal cancer who had received TCM treatment were observed and followed,and a TCM dominant population that achieved significant efficacy was screened out to carry out multivariate regression analysis,further explore key factors that affect survival in advanced digestive tract malignant tumors,and establish a prediction model of TCM dominant population.It will provide reference for the follow-up TCM treatment,and provide reference for development of individualized treatment plans,making the TCM treatment for advanced digestive tract malignant tumors more targeted,and helping to improve the benefit rate in TCM.
文摘In order to estimate the most effect stage and process on population growth and effective conserve the rare endangered plant Davidia involucrata, we analyzed the dynamics and the contributions of life-history components on population dynamics based on Lefkovitch matrix model and sensitivity analysis. The life cycle of Davidia involucrata was divided into six stages (seed, seedling, juvenile, immature, early adult and late adult) based on the species characteristics and published literature data, the survival rates in each life-history stage were simulated using a static life table, and the fecundity of each stage was determined according to sample information. The results showed that the structure of the observed population was not ideal, and the numbers of seedlings and coppice shoots was similar. The population growth rate was influenced largely by individual growth process, and asexual reproduction made a larger contribution to population growth than sexual reproduction. However, sexual reproduction was more important than asexual reproduction, because most asexual reproducing individuals (the coppice shoots) were derived mainly from human destruction (e.g. felling trees). The most important stage was stage V (late adult), associated with seed production and germination. Therefore, conservation of Davidia involucrata populations should focus on stage V and sexual reproduction, in order to improve the seed production and germination rate, and to promote population stability and development.
基金supported by National Natural Science Foundation of China(No.81072389,81373102,81473070 and 81402765)Research Found for the Doctoral Program of Higher Education of China(No.20113234110002)+4 种基金Key Grant of Natural Science Foundation of the Jiangsu Higher Education Institutions of China(No.10KJA330034)College Philosophy and Social Science Foundation from Education Department of Jiangsu Province of China(No.2013SJB790059,2013SJD790032)Research Foundation from Xuzhou Medical College(No.2012KJ02)Research and Innovation Project for College Graduates of Jiangsu Province of China(No.CXLX13_574)the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)
文摘In the past few years, genome-wide association study (GWAS) has made great successes in identifying genetic susceptibility loci underlying many complex diseases and traits. The findings provide important genetic insights into understanding pathogenesis of diseases. In this paper, we present an overview of widely used approaches and strategies for analysis of GWAS, offered a general consideration to deal with GWAS data. The issues regarding data quality control, population structure, association analysis, multiple comparison and visual presentation of GWAS results are discussed; other advanced topics including the issue of missing heritability, meta-analysis, setbased association analysis, copy number variation analysis and GWAS cohort analysis are also briefly introduced.
基金This research is supported by the National Natural Science Foundation of China.
文摘In recent years, population growth models with spatial diffusion have beenextensively studied by many authors (for example, see [1-5]). In this paper, a populationgrowth model is considered with a discrete age-dependence and spatial diffusion, and isinvestigated in a semigroup framework. The spectral properties of the population oper-ator are given. On the basis of such spectral consideration, the asymptotic behaviourof the semigroup generated by the population operator is obtained. Finally, a nonlinearpopulation growth model is considered and its stability is analyzed.
文摘In this paper, a non-smooth population model with impulsive effects is proposed by combining discontinuity and non-smoothness. According to the qualitative theory of differential equations, the global analysis of the model is discussed. Using the theory of impulsive differential equations, the existence conditions of order one periodic solution are obtained. And the impulsive controllers are designed to make the pest populations stay at the refuge level. Some simulations are carried out to prove the results.
文摘In this study, the mathematical models of dynamics of student populations in the university departments are formulated. As a case study, we employ the data of registration section from Department of Mathematics, Faculty of Applied Science, King Mongkut’s University of Technology North Bangkok (KMUTNB), Thailand, from calendar year 2006 to 2010. Using regression analysis, descriptive model and explanatory model are derived. The descriptive model is linear with R2 = 0.8864. Using log-transformation, the explanatory model gives the nonlinear approximation with R2 = 0.8293. The model predicts that the number of students of Department of Mathematics, KMUTNB has a tendency to linearly increase with slope of 20 with 95% CI (6.8417, 33.1583). The application of the models in educational management is discussed.