Use of machine learning models for the prognostication of liver transplantation: A systematic review

BACKGROUND Liver transplantation(LT)is a life-saving intervention for patients with end-stage liver disease.However,the equitable allocation of scarce donor organs remains a formidable challenge.Prognostic tools are pivotal in identifying the most suitable transplant candidates.Traditionally,scoring systems like the model for end-stage liver disease have been instrumental in this process.Nevertheless,the landscape of prognostication is undergoing a transformation with the integration of machine learning(ML)and artificial intelligence models.AIM To assess the utility of ML models in prognostication for LT,comparing their performance and reliability to established traditional scoring systems.METHODS Following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines,we conducted a thorough and standardized literature search using the PubMed/MEDLINE database.Our search imposed no restrictions on publication year,age,or gender.Exclusion criteria encompassed non-English studies,review articles,case reports,conference papers,studies with missing data,or those exhibiting evident methodological flaws.RESULTS Our search yielded a total of 64 articles,with 23 meeting the inclusion criteria.Among the selected studies,60.8%originated from the United States and China combined.Only one pediatric study met the criteria.Notably,91%of the studies were published within the past five years.ML models consistently demonstrated satisfactory to excellent area under the receiver operating characteristic curve values(ranging from 0.6 to 1)across all studies,surpassing the performance of traditional scoring systems.Random forest exhibited superior predictive capabilities for 90-d mortality following LT,sepsis,and acute kidney injury(AKI).In contrast,gradient boosting excelled in predicting the risk of graft-versus-host disease,pneumonia,and AKI.CONCLUSION This study underscores the potential of ML models in guiding decisions related to allograft allocation and LT,marking a significant evolution in the field of prognostication.

Effectiveness of hybrid ensemble machine learning models for landslide susceptibility analysis:Evidence from Shimla district of North-west Indian Himalayan region

The Indian Himalayan region is frequently experiencing climate change-induced landslides.Thus,landslide susceptibility assessment assumes greater significance for lessening the impact of a landslide hazard.This paper makes an attempt to assess landslide susceptibility in Shimla district of the northwest Indian Himalayan region.It examined the effectiveness of random forest(RF),multilayer perceptron(MLP),sequential minimal optimization regression(SMOreg)and bagging ensemble(B-RF,BSMOreg,B-MLP)models.A landslide inventory map comprising 1052 locations of past landslide occurrences was classified into training(70%)and testing(30%)datasets.The site-specific influencing factors were selected by employing a multicollinearity test.The relationship between past landslide occurrences and influencing factors was established using the frequency ratio method.The effectiveness of machine learning models was verified through performance assessors.The landslide susceptibility maps were validated by the area under the receiver operating characteristic curves(ROC-AUC),accuracy,precision,recall and F1-score.The key performance metrics and map validation demonstrated that the BRF model(correlation coefficient:0.988,mean absolute error:0.010,root mean square error:0.058,relative absolute error:2.964,ROC-AUC:0.947,accuracy:0.778,precision:0.819,recall:0.917 and F-1 score:0.865)outperformed the single classifiers and other bagging ensemble models for landslide susceptibility.The results show that the largest area was found under the very high susceptibility zone(33.87%),followed by the low(27.30%),high(20.68%)and moderate(18.16%)susceptibility zones.The factors,namely average annual rainfall,slope,lithology,soil texture and earthquake magnitude have been identified as the influencing factors for very high landslide susceptibility.Soil texture,lineament density and elevation have been attributed to high and moderate susceptibility.Thus,the study calls for devising suitable landslide mitigation measures in the study area.Structural measures,an immediate response system,community participation and coordination among stakeholders may help lessen the detrimental impact of landslides.The findings from this study could aid decision-makers in mitigating future catastrophes and devising suitable strategies in other geographical regions with similar geological characteristics.

Establishing and clinically validating a machine learning model for predicting unplanned reoperation risk in colorectal cancer

BACKGROUND Colorectal cancer significantly impacts global health,with unplanned reoperations post-surgery being key determinants of patient outcomes.Existing predictive models for these reoperations lack precision in integrating complex clinical data.AIM To develop and validate a machine learning model for predicting unplanned reoperation risk in colorectal cancer patients.METHODS Data of patients treated for colorectal cancer(n=2044)at the First Affiliated Hospital of Wenzhou Medical University and Wenzhou Central Hospital from March 2020 to March 2022 were retrospectively collected.Patients were divided into an experimental group(n=60)and a control group(n=1984)according to unplanned reoperation occurrence.Patients were also divided into a training group and a validation group(7:3 ratio).We used three different machine learning methods to screen characteristic variables.A nomogram was created based on multifactor logistic regression,and the model performance was assessed using receiver operating characteristic curve,calibration curve,Hosmer-Lemeshow test,and decision curve analysis.The risk scores of the two groups were calculated and compared to validate the model.RESULTS More patients in the experimental group were≥60 years old,male,and had a history of hypertension,laparotomy,and hypoproteinemia,compared to the control group.Multiple logistic regression analysis confirmed the following as independent risk factors for unplanned reoperation(P<0.05):Prognostic Nutritional Index value,history of laparotomy,hypertension,or stroke,hypoproteinemia,age,tumor-node-metastasis staging,surgical time,gender,and American Society of Anesthesiologists classification.Receiver operating characteristic curve analysis showed that the model had good discrimination and clinical utility.CONCLUSION This study used a machine learning approach to build a model that accurately predicts the risk of postoperative unplanned reoperation in patients with colorectal cancer,which can improve treatment decisions and prognosis.

Unified deep learning model for predicting fundus fluorescein angiography image from fundus structure image

The prediction of fundus fluorescein angiography(FFA)images from fundus structural images is a cutting-edge research topic in ophthalmological image processing.Prediction comprises estimating FFA from fundus camera imaging,single-phase FFA from scanning laser ophthalmoscopy(SLO),and three-phase FFA also from SLO.Although many deep learning models are available,a single model can only perform one or two of these prediction tasks.To accomplish three prediction tasks using a unified method,we propose a unified deep learning model for predicting FFA images from fundus structure images using a supervised generative adversarial network.The three prediction tasks are processed as follows:data preparation,network training under FFA supervision,and FFA image prediction from fundus structure images on a test set.By comparing the FFA images predicted by our model,pix2pix,and CycleGAN,we demonstrate the remarkable progress achieved by our proposal.The high performance of our model is validated in terms of the peak signal-to-noise ratio,structural similarity index,and mean squared error.

Model Agnostic Meta-Learning(MAML)-Based Ensemble Model for Accurate Detection of Wheat Diseases Using Vision Transformer and Graph Neural Networks

Wheat is a critical crop,extensively consumed worldwide,and its production enhancement is essential to meet escalating demand.The presence of diseases like stem rust,leaf rust,yellow rust,and tan spot significantly diminishes wheat yield,making the early and precise identification of these diseases vital for effective disease management.With advancements in deep learning algorithms,researchers have proposed many methods for the automated detection of disease pathogens;however,accurately detectingmultiple disease pathogens simultaneously remains a challenge.This challenge arises due to the scarcity of RGB images for multiple diseases,class imbalance in existing public datasets,and the difficulty in extracting features that discriminate between multiple classes of disease pathogens.In this research,a novel method is proposed based on Transfer Generative Adversarial Networks for augmenting existing data,thereby overcoming the problems of class imbalance and data scarcity.This study proposes a customized architecture of Vision Transformers(ViT),where the feature vector is obtained by concatenating features extracted from the custom ViT and Graph Neural Networks.This paper also proposes a Model AgnosticMeta Learning(MAML)based ensemble classifier for accurate classification.The proposedmodel,validated on public datasets for wheat disease pathogen classification,achieved a test accuracy of 99.20%and an F1-score of 97.95%.Compared with existing state-of-the-art methods,this proposed model outperforms in terms of accuracy,F1-score,and the number of disease pathogens detection.In future,more diseases can be included for detection along with some other modalities like pests and weed.

Extensive identification of landslide boundaries using remote sensing images and deep learning method

The frequent occurrence of extreme weather events has rendered numerous landslides to a global natural disaster issue.It is crucial to rapidly and accurately determine the boundaries of landslides for geohazards evaluation and emergency response.Therefore,the Skip Connection DeepLab neural network(SCDnn),a deep learning model based on 770 optical remote sensing images of landslide,is proposed to improve the accuracy of landslide boundary detection.The SCDnn model is optimized for the over-segmentation issue which occurs in conventional deep learning models when there is a significant degree of similarity between topographical geomorphic features.SCDnn exhibits notable improvements in landslide feature extraction and semantic segmentation by combining an enhanced Atrous Spatial Pyramid Convolutional Block(ASPC)with a coding structure that reduces model complexity.The experimental results demonstrate that SCDnn can identify landslide boundaries in 119 images with MIoU values between 0.8and 0.9;while 52 images with MIoU values exceeding 0.9,which exceeds the identification accuracy of existing techniques.This work can offer a novel technique for the automatic extensive identification of landslide boundaries in remote sensing images in addition to establishing the groundwork for future inve stigations and applications in related domains.

Analysis of the Role of Problem-Based Independent Learning Model in Teaching Cerebral Ischemic Stroke First Aid in Emergency Medicine

Objective:To analyze the effect of using a problem-based(PBL)independent learning model in teaching cerebral ischemic stroke(CIS)first aid in emergency medicine.Methods:90 interns in the emergency department of our hospital from May 2022 to May 2023 were selected for the study.They were divided into Group A(45,conventional teaching method)and Group B(45 cases,PBL independent learning model)by randomized numerical table method to compare the effects of the two groups.Results:The teaching effect indicators and student satisfaction scores in Group B were higher than those in Group A(P<0.05).Conclusion:The use of the PBL independent learning model in the teaching of CIS first aid can significantly improve the teaching effect and student satisfaction.

Parallel Inference for Real-Time Machine Learning Applications

Hyperparameter tuning is a key step in developing high-performing machine learning models, but searching large hyperparameter spaces requires extensive computation using standard sequential methods. This work analyzes the performance gains from parallel versus sequential hyperparameter optimization. Using scikit-learn’s Randomized SearchCV, this project tuned a Random Forest classifier for fake news detection via randomized grid search. Setting n_jobs to -1 enabled full parallelization across CPU cores. Results show the parallel implementation achieved over 5× faster CPU times and 3× faster total run times compared to sequential tuning. However, test accuracy slightly dropped from 99.26% sequentially to 99.15% with parallelism, indicating a trade-off between evaluation efficiency and model performance. Still, the significant computational gains allow more extensive hyperparameter exploration within reasonable timeframes, outweighing the small accuracy decrease. Further analysis could better quantify this trade-off across different models, tuning techniques, tasks, and hardware.

Progress in Neural NLP:Modeling,Learning,and Reasoning

Natural language processing(NLP)is a subfield of artificial intelligence that focuses on enabling computers to understand and process human languages.In the last five years,we have witnessed the rapid development of NLP in tasks such as machine translation,question-answering,and machine reading comprehension based on deep learning and an enormous volume of annotated and unannotated data.In this paper,we will review the latest progress in the neural network-based NLP framework(neural NLP)from three perspectives:modeling,learning,and reasoning.In the modeling section,we will describe several fundamental neural network-based modeling paradigms,such as word embedding,sentence embedding,and sequence-to-sequence modeling,which are widely used in modern NLP engines.In the learning section,we will introduce widely used learning methods for NLP models,including supervised,semi-supervised,and unsupervised learning;multitask learning;transfer learning;and active learning.We view reasoning as a new and exciting direction for neural NLP,but it has yet to be well addressed.In the reasoning section,we will review reasoning mechanisms,including the knowledge,existing non-neural inference methods,and new neural inference methods.We emphasize the importance of reasoning in this paper because it is important for building interpretable and knowledgedriven neural NLP models to handle complex tasks.At the end of this paper,we will briefly outline our thoughts on the future directions of neural NLP.

Landslide susceptibility prediction using slope unit-based machine learning models considering the heterogeneity of conditioning factors

To perform landslide susceptibility prediction(LSP),it is important to select appropriate mapping unit and landslide-related conditioning factors.The efficient and automatic multi-scale segmentation(MSS)method proposed by the authors promotes the application of slope units.However,LSP modeling based on these slope units has not been performed.Moreover,the heterogeneity of conditioning factors in slope units is neglected,leading to incomplete input variables of LSP modeling.In this study,the slope units extracted by the MSS method are used to construct LSP modeling,and the heterogeneity of conditioning factors is represented by the internal variations of conditioning factors within slope unit using the descriptive statistics features of mean,standard deviation and range.Thus,slope units-based machine learning models considering internal variations of conditioning factors(variant slope-machine learning)are proposed.The Chongyi County is selected as the case study and is divided into 53,055 slope units.Fifteen original slope unit-based conditioning factors are expanded to 38 slope unit-based conditioning factors through considering their internal variations.Random forest(RF)and multi-layer perceptron(MLP)machine learning models are used to construct variant Slope-RF and Slope-MLP models.Meanwhile,the Slope-RF and Slope-MLP models without considering the internal variations of conditioning factors,and conventional grid units-based machine learning(Grid-RF and MLP)models are built for comparisons through the LSP performance assessments.Results show that the variant Slopemachine learning models have higher LSP performances than Slope-machine learning models;LSP results of variant Slope-machine learning models have stronger directivity and practical application than Grid-machine learning models.It is concluded that slope units extracted by MSS method can be appropriate for LSP modeling,and the heterogeneity of conditioning factors within slope units can more comprehensively reflect the relationships between conditioning factors and landslides.The research results have important reference significance for land use and landslide prevention.

Masked Face Recognition Using MobileNet V2 with Transfer Learning

Corona virus(COVID-19)is once in a life time calamity that has resulted in thousands of deaths and security concerns.People are using face masks on a regular basis to protect themselves and to help reduce corona virus transmission.During the on-going coronavirus outbreak,one of the major priorities for researchers is to discover effective solution.As important parts of the face are obscured,face identification and verification becomes exceedingly difficult.The suggested method is a transfer learning using MobileNet V2 based technology that uses deep feature such as feature extraction and deep learning model,to identify the problem of face masked identification.In the first stage,we are applying face mask detector to identify the face mask.Then,the proposed approach is applying to the datasets from Canadian Institute for Advanced Research10(CIFAR10),Modified National Institute of Standards and Technology Database(MNIST),Real World Masked Face Recognition Database(RMFRD),and Stimulated Masked Face Recognition Database(SMFRD).The proposed model is achieving recognition accuracy 99.82%with proposed dataset.This article employs the four pre-programmed models VGG16,VGG19,ResNet50 and ResNet101.To extract the deep features of faces with VGG16 is achieving 99.30%accuracy,VGG19 is achieving 99.54%accuracy,ResNet50 is achieving 78.70%accuracy and ResNet101 is achieving 98.64%accuracy with own dataset.The comparative analysis shows,that our proposed model performs better result in all four previous existing models.The fundamental contribution of this study is to monitor with face mask and without face mask to decreases the pace of corona virus and to detect persons using wearing face masks.

Ensemble Deep Learning Framework for Situational Aspects-Based Annotation and Classification of International Student’s Tweets during COVID-19

As the COVID-19 pandemic swept the globe,social media plat-forms became an essential source of information and communication for many.International students,particularly,turned to Twitter to express their struggles and hardships during this difficult time.To better understand the sentiments and experiences of these international students,we developed the Situational Aspect-Based Annotation and Classification(SABAC)text mining framework.This framework uses a three-layer approach,combining baseline Deep Learning(DL)models with Machine Learning(ML)models as meta-classifiers to accurately predict the sentiments and aspects expressed in tweets from our collected Student-COVID-19 dataset.Using the pro-posed aspect2class annotation algorithm,we labeled bulk unlabeled tweets according to their contained aspect terms.However,we also recognized the challenges of reducing data’s high dimensionality and sparsity to improve performance and annotation on unlabeled datasets.To address this issue,we proposed the Volatile Stopwords Filtering(VSF)technique to reduce sparsity and enhance classifier performance.The resulting Student-COVID Twitter dataset achieved a sophisticated accuracy of 93.21%when using the random forest as a meta-classifier.Through testing on three benchmark datasets,we found that the SABAC ensemble framework performed exceptionally well.Our findings showed that international students during the pandemic faced various issues,including stress,uncertainty,health concerns,financial stress,and difficulties with online classes and returning to school.By analyzing and summarizing these annotated tweets,decision-makers can better understand and address the real-time problems international students face during the ongoing pandemic.

Hemodynamic Analysis and Diagnosis Based on Multi-Deep Learning Models

This study employs nine distinct deep learning models to categorize 12,444 blood cell images and automatically extract from them relevant information with an accuracy that is beyond that achievable with traditional techniques.The work is intended to improve current methods for the assessment of human health through measurement of the distribution of four types of blood cells,namely,eosinophils,neutrophils,monocytes,and lymphocytes,known for their relationship with human body damage,inflammatory regions,and organ illnesses,in particular,and with the health of the immune system and other hazards,such as cardiovascular disease or infections,more in general.The results of the experiments show that the deep learning models can automatically extract features from the blood cell images and properly classify them with an accuracy of 98%,97%,and 89%,respectively,with regard to the training,verification,and testing of the corresponding datasets.

Deep Transfer Learning Approach for Robust Hand Detection

Human hand detection in uncontrolled environments is a challenging visual recognition task due to numerous variations of hand poses and background image clutter.To achieve highly accurate results as well as provide real-time execution,we proposed a deep transfer learning approach over the state-of-the-art deep learning object detector.Our method,denoted as YOLOHANDS,is built on top of the You Only Look Once(YOLO)deep learning architecture,which is modified to adapt to the single class hand detection task.The model transfer is performed by modifying the higher convolutional layers including the last fully connected layer,while initializing lower non-modified layers with the generic pre-trained weights.To address robustness issues,we introduced a comprehensive augmentation procedure over the training image dataset,specifically adapted for the hand detection problem.Experimental evaluation of the proposed method,which is performed on a challenging public dataset,has demonstrated highly accurate results,comparable to the state-of-the-art methods.

Correction of CMPAS Precipitation Products over Complex Terrain Areas with Machine Learning Models

Machine learning models were used to improve the accuracy of China Meteorological Administration Multisource Precipitation Analysis System(CMPAS)in complex terrain areas by combining rain gauge precipitation with topographic factors like altitude,slope,slope direction,slope variability,surface roughness,and meteorological factors like temperature and wind speed.The results of the correction demonstrated that the ensemble learning method has a considerably corrective effect and the three methods(Random Forest,AdaBoost,and Bagging)adopted in the study had similar results.The mean bias between CMPAS and 85%of automatic weather stations has dropped by more than 30%.The plateau region displays the largest accuracy increase,the winter season shows the greatest error reduction,and decreasing precipitation improves the correction outcome.Additionally,the heavy precipitation process’precision has improved to some degree.For individual stations,the revised CMPAS error fluctuation range is significantly reduced.

Automatic Image Annotation Using Adaptive Convolutional Deep Learning Model

Every day,websites and personal archives create more and more photos.The size of these archives is immeasurable.The comfort of use of these huge digital image gatherings donates to their admiration.However,not all of these folders deliver relevant indexing information.From the outcomes,it is dif-ficult to discover data that the user can be absorbed in.Therefore,in order to determine the significance of the data,it is important to identify the contents in an informative manner.Image annotation can be one of the greatest problematic domains in multimedia research and computer vision.Hence,in this paper,Adap-tive Convolutional Deep Learning Model(ACDLM)is developed for automatic image annotation.Initially,the databases are collected from the open-source system which consists of some labelled images(for training phase)and some unlabeled images{Corel 5 K,MSRC v2}.After that,the images are sent to the pre-processing step such as colour space quantization and texture color class map.The pre-processed images are sent to the segmentation approach for efficient labelling technique using J-image segmentation(JSEG).Thefinal step is an auto-matic annotation using ACDLM which is a combination of Convolutional Neural Network(CNN)and Honey Badger Algorithm(HBA).Based on the proposed classifier,the unlabeled images are labelled.The proposed methodology is imple-mented in MATLAB and performance is evaluated by performance metrics such as accuracy,precision,recall and F1_Measure.With the assistance of the pro-posed methodology,the unlabeled images are labelled.

Design of N-11-Azaartemisinins Potentially Active against Plasmodium falciparum by Combined Molecular Electrostatic Potential, Ligand-Receptor Interaction and Models Built with Supervised Machine Learning Methods

N-11-azaartemisinins potentially active against Plasmodium falciparum are designed by combining molecular electrostatic potential (MEP), ligand-receptor interaction, and models built with supervised machine learning methods (PCA, HCA, KNN, SIMCA, and SDA). The optimization of molecular structures was performed using the B3LYP/6-31G* approach. MEP maps and ligand-receptor interactions were used to investigate key structural features required for biological activities and likely interactions between N-11-azaartemisinins and heme, respectively. The supervised machine learning methods allowed the separation of the investigated compounds into two classes: cha and cla, with the properties εLUMO+1 (one level above lowest unoccupied molecular orbital energy), d(C6-C5) (distance between C6 and C5 atoms in ligands), and TSA (total surface area) responsible for the classification. The insights extracted from the investigation developed and the chemical intuition enabled the design of sixteen new N-11-azaartemisinins (prediction set), moreover, models built with supervised machine learning methods were applied to this prediction set. The result of this application showed twelve new promising N-11-azaartemisinins for synthesis and biological evaluation.

Weighted Forwarding in Graph Convolution Networks for Recommendation Information Systems

Recommendation Information Systems(RIS)are pivotal in helping users in swiftly locating desired content from the vast amount of information available on the Internet.Graph Convolution Network(GCN)algorithms have been employed to implement the RIS efficiently.However,the GCN algorithm faces limitations in terms of performance enhancement owing to the due to the embedding value-vanishing problem that occurs during the learning process.To address this issue,we propose a Weighted Forwarding method using the GCN(WF-GCN)algorithm.The proposed method involves multiplying the embedding results with different weights for each hop layer during graph learning.By applying the WF-GCN algorithm,which adjusts weights for each hop layer before forwarding to the next,nodes with many neighbors achieve higher embedding values.This approach facilitates the learning of more hop layers within the GCN framework.The efficacy of the WF-GCN was demonstrated through its application to various datasets.In the MovieLens dataset,the implementation of WF-GCN in LightGCN resulted in significant performance improvements,with recall and NDCG increasing by up to+163.64%and+132.04%,respectively.Similarly,in the Last.FM dataset,LightGCN using WF-GCN enhanced with WF-GCN showed substantial improvements,with the recall and NDCG metrics rising by up to+174.40%and+169.95%,respectively.Furthermore,the application of WF-GCN to Self-supervised Graph Learning(SGL)and Simple Graph Contrastive Learning(SimGCL)also demonstrated notable enhancements in both recall and NDCG across these datasets.

A hierarchical enhanced data-driven battery pack capacity estimation framework for real-world operating conditions with fewer labeled data

Battery pack capacity estimation under real-world operating conditions is important for battery performance optimization and health management,contributing to the reliability and longevity of batterypowered systems.However,complex operating conditions,coupling cell-to-cell inconsistency,and limited labeled data pose great challenges to accurate and robust battery pack capacity estimation.To address these issues,this paper proposes a hierarchical data-driven framework aimed at enhancing the training of machine learning models with fewer labeled data.Unlike traditional data-driven methods that lack interpretability,the hierarchical data-driven framework unveils the“mechanism”of the black box inside the data-driven framework by splitting the final estimation target into cell-level and pack-level intermediate targets.A generalized feature matrix is devised without requiring all cell voltages,significantly reducing the computational cost and memory resources.The generated intermediate target labels and the corresponding features are hierarchically employed to enhance the training of two machine learning models,effectively alleviating the difficulty of learning the relationship from all features due to fewer labeled data and addressing the dilemma of requiring extensive labeled data for accurate estimation.Using only 10%of degradation data,the proposed framework outperforms the state-of-the-art battery pack capacity estimation methods,achieving mean absolute percentage errors of 0.608%,0.601%,and 1.128%for three battery packs whose degradation load profiles represent real-world operating conditions.Its high accuracy,adaptability,and robustness indicate the potential in different application scenarios,which is promising for reducing laborious and expensive aging experiments at the pack level and facilitating the development of battery technology.

Mapping soil organic matter in cultivated land based on multi-year composite images on monthly time scales

Rapid and accurate acquisition of soil organic matter(SOM)information in cultivated land is important for sustainable agricultural development and carbon balance management.This study proposed a novel approach to predict SOM with high accuracy using multiyear synthetic remote sensing variables on a monthly scale.We obtained 12 monthly synthetic Sentinel-2 images covering the study area from 2016 to 2021 through the Google Earth Engine(GEE)platform,and reflectance bands and vegetation indices were extracted from these composite images.Then the random forest(RF),support vector machine(SVM)and gradient boosting regression tree(GBRT)models were tested to investigate the difference in SOM prediction accuracy under different combinations of monthly synthetic variables.Results showed that firstly,all monthly synthetic spectral bands of Sentinel-2 showed a significant correlation with SOM(P<0.05)for the months of January,March,April,October,and November.Secondly,in terms of single-monthly composite variables,the prediction accuracy was relatively poor,with the highest R^(2)value of 0.36 being observed in January.When monthly synthetic environmental variables were grouped in accordance with the four quarters of the year,the first quarter and the fourth quarter showed good performance,and any combination of three quarters was similar in estimation accuracy.The overall best performance was observed when all monthly synthetic variables were incorporated into the models.Thirdly,among the three models compared,the RF model was consistently more accurate than the SVM and GBRT models,achieving an R^(2)value of 0.56.Except for band 12 in December,the importance of the remaining bands did not exhibit significant differences.This research offers a new attempt to map SOM with high accuracy and fine spatial resolution based on monthly synthetic Sentinel-2 images.