A Meta-Analysis of the Prognostic and Clinicopathological Significance of circZFR in Human Gastrointestinal Cancers

Background: Studies of gastrointestinal (GIT) cancers have shown that circZFR could be involved in the development and progression of various GIT cancers. However, small sample sizes limit the clinical significance of these studies. Here, a meta-analysis was conducted to ascertain the actual involvement of circZFR in the development and prognosis of GIT cancers. Methods: PubMed, Embase, Web of Science, and the Cochrane Library were searched up to December 31, 2023. Hazard ratios (HRs) or odds ratios (ORs) with 95% confidence intervals (CIs) were pooled to evaluate the association between circZFR expression and overall survival (OS). Publication bias was measured using the funnel plot and Egger’s test. Results: 10 studies having 659 participants were enrolled for meta-analysis. High circZFR expression was associated with poor OS (HR = 1.4, 95% CI: 1.20, 1.70). High circZFR expression also predicted larger tumor size (OR = 4.38, 95% CI 2.65, 7.25), advanced clinical stage (OR = 5.33, 95% CI 3.10, 9.16), and tendency for distant metastasis (OR = 2.89, 95% CI: 1.62, 5.11), but was not related to age, gender, and histological grade. Conclusions: In summary, high circZFR expression was associated with poor OS, larger tumor size, advanced stage cancer and tendency for distant metastasis. These findings suggested that circZFR could be a prognostic marker for GIT cancers.

Flower morphology of Allium(Amaryllidaceae)and its systematic significance

Allium is a complicated genus that includes approximately 1000 species.Although its morphology is well studied,the taxonomic importance of many morphological traits,including floral traits,are poorly understood.Here,we examined and measured the floral characteristics of 87 accessions of 74 Allium taxa(belonging to 30 sections and nine subgenera)from Central to Eastern Asian countries.We then examined the taxonomic relationships between select flower characteristics and a phylogenetic tree based on ITS sequences.Our results confirm that floral morphology provides key taxonomic information to assess species delimitation in Allium.We found that perianth color is an important characteristic within the subg.Melanocrommyum,Polyprason,and Reticulatobulbosa.In subg.Allium,Cepa,and Rhizirideum,significant characteristics include ovary shape,perianth shape,and inner tepal apex.For species in subg.Angunium,the key taxonomic character is ovule number(only one ovule in per locule).In the subg.Allium,Cepa,Polyprason,and Reticulatobulbosa,which belong to the third evolutionary line of Allium,hood-like appendages occur in the ovary,although these do not occur in subg.Rhizirideum.Our results also indicated that the flower morphology of several species in some sections are not clearly distinguished,e.g.,sect.Sacculiferum(subg.Cepa)and sect.Tenuissima(subg.Rhizirideum).This study provides detailed photographs and descriptions of floral characteristics and information on general distributions,habitats,and phenology of the studied taxa.

Genesis and geological significance of carbonate in Changdu Basin,Xizang,China:Constraints from geochemistry and C-O isotopes

Research on the origin of carbonates in Changdu Basin holds significant importance for understanding the regional potash formation model.Based on a comprehensive review of previous studies,field geological surveys,and laboratory investigations,this study analyzes the origin and properties of carbonates within the context of regional potash formation.Petrographic studies show that magnesite deposits,with the characteristics of sedimentary origin.The results of elemental geochemical analysis show that the carbonates in this area were formed in the sedimentary environment via evaporation followed by concentration,and the formation of magnesite was possibly caused by the substitution of calcium in the dolomite with magnesium-rich brine.Theδ^(13)C values of carbonats in the study area are between5.9‰and 9.1‰.Theδ^(18)O values of magnesite samples range from-7.3‰to-1.3‰,and theδ^(18)O values of dolomites range from-10.3‰to-8.4‰.All the calculated Z values of oxygen isotopes of carbonates greater than 120.A comprehensive analysis of carbon and oxygen isotopes indicates that the magnesite was formed in a highly concentrated Marine sedimentary environment and does not show any relation with the metasomatism of hydrothermal fluids.The results on the correlation of magnesite with seawater and its sedimentary origin provide key information for explaining the migration direction of brine between the Changdu and Lanping-Simao Basins.The residual metamorphic seawater in the Changdu Basin migrated to the Lanping-Simao Basin,where potash underwent deposition.Whereas,magnesite and dolomite in the early stage of potash formation were left in the Changdu Basin.

Microscopic characteristics and geological significance of pyrite in shales of the Wufeng-Longmaxi formations,southeastern Chongqing,China

Shales of the Wufeng-Longmaxi formations in the basin-margin transition zone of southeastern Chongqing,China are characterized by high organic matter content and a significant presence of pyrite development.By examining numerous scanning electron microscope(SEM)images and considering the crystal and aggregate characteristics of minerals,we identified four types of pyrite in the study area:euhedral crystals,irregular aggregates,framboidal aggregates,and metasomatized organisms.Among these types,framboidal aggregates are the most prevalent.The formation mechanism of framboidal pyrite can be categorized into inorganic and organic origins.As inferred from the pyrite characteristics in the study area,the formation mechanism of the metasomatized organisms aligns with the biologically induced mineralization mode of organic origin,whereas the framboidal aggregates are more associated with the biologically controlled mineralization mode of organic origin.This underscores a close relationship between the pyrite formation and organic matter,which in turn indicates that an organic origin is more consistent with the pyrite characteristics observed in this study area.The pyrite morphology can reflect reactive iron concentration.Euhedral pyrite crystals tend to form under a low reactive iron concentration,whereas the formation of framboidal pyrite requires a high reactive iron concentration.Additionally,the type and grain size of pyrite aggregates can reflect variations in the redox conditions of the depositional environment.Pyrite produces positive effects on reservoir storage space,with intercrystalline organic pores,intercrystalline pores,and mold pores associated with pyrite contributing greatly to the storage spaces.

Nomogram to predict gas-related complications during transoral endoscopic resection of upper gastrointestinal submucosal lesions:Clinical significance

Transoral endoscopic resections in treating upper gastrointestinal submucosal lesions have the advantages of maintaining the integrity of the gastrointestinal lumen,avoiding perforation and reducing gastrointestinal fistulae.They are becoming more widely used in clinical practice,but,they may also present a variety of complications.Gas-related complications are one of the most common,which can be left untreated if the symptoms are mild,but in severe cases,they can lead to rapid changes in the respiratory and circulatory systems in a short period,which can be life-threatening.Therefore,it is important to predict the occurrence of gas-related complications early and take preventive measures actively.Based on the authors'results in the prepublication of the article“Nomogram to predict gas-related complications during transoral endoscopic resection of upper gastrointestinal submucosal lesions,”and in conjunction with our evaluation and additions to the relevant content,radiographs may help screen patients at high risk for gas-related complications.Controlling blood glucose levels,shortening the duration of surgery,and choosing the most appropriate surgical resection may positively impact the prognosis of patients at high risk for gas-related complications during transoral endoscopic resection of upper gastrointestinal submucosal lesions.

Three-dimensional structural models,evolution and petroleum geological significances of transtensional faults in the Ziyang area,central Sichuan Basin,SW China

With drilling and seismic data of Transtensional(strike-slip)Fault System in the Ziyang area of the central Sichuan Basin,SW China plane-section integrated structural interpretation,3-D fault framework model building,fault throw analyzing,and balanced profile restoration,it is pointed out that the transtensional fault system in the Ziyang 3-D seismic survey consists of the northeast-trending F_(I)19 and F_(I)20 fault zones dominated by extensional deformation,as well as 3 sets of northwest-trending en echelon normal faults experienced dextral shear deformation.Among them,the F_(I)19 and F_(I)20 fault zones cut through the Neoproterozoic to Lower Triassic Jialingjiang Formation,presenting a 3-D structure of an“S”-shaped ribbon.And before Permian and during the Early Triassic,the F_(I)19 and F_(I)20 fault zones underwent at least two periods of structural superimposition.Besides,the 3 sets of northwest-trending en echelon normal faults are composed of small normal faults arranged in pairs,with opposite dip directions and partially left-stepped arrangement.And before Permian,they had formed almost,restricting the eastward growth and propagation of the F_(I)19 fault zone.The F_(I)19 and F_(I)20 fault zones communicate multiple sets of source rocks and reservoirs from deep to shallow,and the timing of fault activity matches well with oil and gas generation peaks.If there were favorable Cambrian-Triassic sedimentary facies and reservoirs developing on the local anticlinal belts of both sides of the F_(I)19 and F_(I)20 fault zones,the major reservoirs in this area are expected to achieve breakthroughs in oil and gas exploration.

A Study on the Educational Significance Guidance Plan Value of the Jumong Myth Using STEAM

Jumong is a legendary figure in Korean mythology.He is depicted as a genius archer,a brilliant mind with horses,a god who rules the rivers and the sky.Jumong is a mythical character who is believed to be of divine descent and to possess superhuman abilities that humans cannot match.The myth of Jumong is a very competitive content that can compete on a global scale.However,in order for it to be successful,it is necessary to be able to reinterpret our mythology to suit the times and reproduce it culturally.To this end,the realistic globalization of Korean classical literature should commence with the genre of Korean mythology.This paper presents the educational significance of the Jumong myth as a teaching-learning model,via STEAM(science,technology,engineering,arts,and mathematics),on the theme of Korean mythology.As we enter the era of artificial intelligence(AI)through the 4th Industrial Revolution,the most appropriate teaching and learning method,the convergence class,will provide an opportunity for students living in modern times to discover the cultural archetypes that allow them to recognise themselves as individuals and us as a collective,and to find the roots of the myth to positively renew their identity.Furthermore,it is my hope that they will rediscover and appreciate the representative work of Korean mythology,Gojomong,the eponymous story of Goguryeo.

Expression of CD151 in Gastric Cancer Tissues and Its Clinical Significance

Objective:To explore the expression of CD151 in gastric cancer tissues and its clinical significance.Methods:Immunohistochemistry was employed to detect the expression of CD151 in gastric cancer tissues and adjacent normal tissues.The relationship between CD151 expression and the clinicopathological characteristics of gastric cancer was analyzed.Results:The expression of CD151 in gastric cancer tissues was significantly higher than in adjacent normal tissues(P<0.05).It was associated with the degree of differentiation,depth of invasion,lymph node metastasis,and TNM staging of gastric cancer.The survival time of patients with high CD151 expression was significantly shorter than that of those with low expression(P<0.05).Conclusion:High expression of CD151 in gastric cancer tissues is correlated with the malignant biological behavior of gastric cancer and can serve as an indicator for evaluating the prognosis of gastric cancer.

Exploring the Significance and Implementation Strategies of Mental Health Education for College Students

College students are influenced by diverse cultures in the new era,thus their inner world is rich and changing rapidly.The acceleration of social rhythm can easily lead to different kinds of psychological problems.Mental health education is people-oriented,using scientific methods and means to train high-quality talents with all-round development across the world.A healthy psychological state can promote the sound development of students,make them establish correct core social values,and realize self-value.At present,there are some problems in university mental health education,such as single form and imperfect system.At the same time,college education plays an important role in the formation of ideas for college students’ideological values.As a front-line student worker,college counselors should cooperate with the school’s psychological departments to improve the college psychological education system,rationally plan the psychological teaching program,and pay attention to the college students’mental health education.The government should also take into account the need to ensure that the education system is not undermined by the lack of a comprehensive and effective education system.

Analysis of the Significance of Key Points of Patient Interventional Psychological Care and Pain Care

Interventional therapy has become increasingly popular in clinical practice due to advancements in medical technology.However,patients often experience psychological and physiological pressure due to its invasive nature.The management of patient discomfort and tension is crucial to ensure effective treatment.Psychological and pain management are essential components of interventional therapy,as they significantly impact patient recovery and prognosis.This article discussed the importance of interventional psychological and pain care for patients,starting with the development and spread of interventional therapy.The significance of providing high-quality nursing services to patients and improving their quality of life was also discussed.

基于C#．NET的GSMMODEM短信猫应用设计开发

短信猫(GSM MODEM)是无线数据通信应用的重要组成部分。这里主要研究短信猫应用软件开发,介绍GSMMODEM短信猫的开发架构和应用软件开发流程,重点是运用C#语言在Visual Studio 2005编译器平台下实现GSM MO-DEM的应用开发。然后在GSM MODEM短信猫上进行调试,通过多次调试验证,与VB,VC,Java等语言开发的应用软件相比,软件用户界面友好,运行稳定,可靠性高。

基于MODEM和单片机的远程通讯系统设计与实现

本文着重介绍基于８９Ｃ５１单片机和调制解调器件ＳＴ７５３６的通讯接口电路设计、软件实现方法、远程数据采集及多机通讯接口。

Win32环境下Modem数据传输实现方法及通信协议研究

对Win98/NT环境下的串口通信和Modem的编程方法进行研究 ,通过串行端口发送数据控制Mo dem的命令状态和在线状态 ,实现数据的模拟信道传输。同时对传输过程中的通信协议进行探索和改进 。

一种基于VC的Modem分布式远程监控系统设计

针对边远地区光伏电站不易值守的问题,本文设计了一种利用VC开发Modem通信来实施远程监控的系统。系统按分布式结构设计,可实现对多个电站的实时监控。实践证明,该系统经济稳定、操作方便。

利用MODEM芯片实现单片机远程通讯

介绍了利用MODEM芯片实现单片机远程通讯。着重分析73K222AL芯片的结构特征,设计出MODEM芯片与AT89C51的接口电路,并给出BELL 103协议下通讯呼叫连接过程的部分程序。

一种室内电力线载波MODEM的实现

本文对利用室内电力线路进行数据通信的有关问题进行了探讨，简述了采用电力线路作为通信信道的概况和存在的问题。对于实验室环境下的电力线路信道的特性进行了初步分析，提供了一种实现室内电力载波ＭＯＤＥＭ的方法。

基于高速Modem的电力线载波数字接入技术

介绍了在开发数字式电力线载波通信系统过程中涉及的一项关键技术——电力线载波数字接入技术。数字式电力线载波通信系统采用话音压缩、数字编码、数字复接等技术 ,完成话音与远动数据的汇合 ,以 TCM(格栅编码调制 )方式在电力线上传输高频信号 ,在接收端采用 TCM解调、Viterbi译码、自适应均衡等技术再生恢复出原始信息。其中高速 Modem采用 AD公司 Modem专用开发芯片 ADSP— 2 1 mod870 ,以一整套软、硬件解决方案高效实现了专用

专线MODEM在远程通信系统中的应用

目前远程视频监控系统已经成为计算机监控系统的重要分支。国内外现有的远程监控系统大多基于光纤,而光纤如果遇到机械冲击、碰撞等都会造成光缆断缆或断芯,光缆断裂后,很难快速修复,且修复设备复杂,普通用户根本无法进行焊接修复,再加上光端机价格较高,这些都限制了光纤远程监控系统的应用和普及。为此,人们找到了价格相对便宜、维护十分简单的极低比特率双绞线解决方案。文中以基于MODEM专线方式的远程视频监控系统为例,介绍经济、实用且具有广播能力的远程网络摄像机系统。

基于Modem和单片机的远程数据监测系统的设计

介绍了如何用 AT89C5 2单片机控制调制解调器件 MSM75 12 ,通过电话线传输数据 ,并给出了硬件原理图及部分程序清单。

基于电力Modem的远程电表联网自动抄表监控系统的研究

本文介绍基于ST电力线Modem器件ST7536和单片机89C51的电表联网管理系统设计以及多机通讯技术，其特点是可以不占用其它通讯电缆，安装使用方便，经济实用。