Dysfunctional attitudes,social support,negative life events,and depressive symptoms in Chinese adolescents:A moderated mediation model

BACKGROUND Depression is a prevalent psychological issue in adolescents that is significantly related to negative life events(NLEs)and dysfunctional attitudes.High levels of social support can significantly buffer NLEs’effect on depression.Currently,there is limited research on how social support moderates the relationship between NLEs,dysfunctional attitudes,and depression in adolescents in China.It is imperative to investigate this moderating effect to mitigate dysfunctional attitudes in adolescent undergoing depressive mood,ultimately enhancing their overall mental health.AIM To investigate the relationship and underlying mechanisms between specific dysfunctional attitudes,social support,and depression among Chinese adolescents.METHODS This is a cross-sectional study which selected five middle schools in Shandong Province for investigation in March 2022.Participants included 795 adolescents(49.87%male,mage=15.15,SD=1.84,age range=11-18 years old).All participants completed the Dysfunctional Attitude Scale,Adolescent Life Event Scale,Beck Depression Inventory,and Social Support Rating Scale.A moderated mediation model was conducted to examine the relationship between specific dysfunctional attitudes,social support,and depression.RESULTS Results indicated that NLEs affected depression through the mediating role of specific dysfunctional attitudes(autonomy attitudesβ=0.21;perfectionismβ=0.25).Moreover,social support was found to moderate the mediating effect between NLEs,specific dysfunctional attitudes,and depressive symptoms(autonomy attitudes b2=-0.08;perfectionism b2=-0.09).CONCLUSION Dysfunctional attitudes mediated and social support moderated the relationship between NLEs and depression.Social support can buffer depression symptoms among adolescents with autonomy attitudes and perfectionism.

Suppressive effects of exercise-conditioned serum on cancer cells:A narrative review of the influence of exercise mode,volume,and intensity

Cancer is a major cause of morbidity and mortality worldwide,and the incidence is increasing,highlighting the need for effective strategies to treat this disease.Exercise has emerged as fundamental therapeutic medicine in the management of cancer,associated with a lower risk of recur-rence and increased survival.Several avenues of research demonstrate reduction in growth,proliferation,and increased apoptosis of cancer cells,including breast,prostate,colorectal,and lung cancer,when cultured by serum collected after exercise in vitro(i.e.,the cultivation of cancer cell lines in an experimental setting,which simplifies the biological system and provides mechanistic insight into cell responses).The underlying mechanisms of exercise-induced cancer suppressive effects may be attributed to the alteration in circulating factors,such as skeletal muscle-induced cytokines(i.e.,myokines)and hormones.However,exercise-induced tumor suppressive effects and detailed information about training interventions are not well investigated,constraining more precise application of exercise medicine within clinical oncology.To date,it remains unclear what role different training modes(i.e.,resistance and aerobic training)as well as volume and intensity have on exercise-condi-tioned serum and its effects on cancer cells.Nevertheless,the available evidence is that a single bout of aerobic training at moderate to vigorous intensity has cancer suppressive effects,while for chronic training interventions,exercise volume appears to be an influential candidate driving cancer inhibitory effects regardless of training mode.Insights for future research investigating training modes,volume and intensity are provided to further our understanding of the effects of exercise-conditioned serum on cancer cells.

Marital Status as a Moderator:Exploring the Relationship between Social Engagement and Depressive Symptoms in China’s Older Adult Population

Objective This study aims to explore the complex relationship between social engagement and depressive symptoms among older adults in China,focusing particularly on the moderating role of marital status.Methods This study used data from the latest Chinese Longitudinal Healthy Longevity Survey(CLHLS).The analysis used the latent class analysis to delineate personality clusters and hierarchical linear regression,supplemented by the PROCESS macro,to investigate the effects of social engagement and marital status on depressive symptoms.Results The analysis encompassed 7,789 respondents(mean age:82.53[s=11.20]years),with 54%female.The personality analysis categorized participants into four clusters,with the majority(77.60%)classified as Confident Idealists,who exhibited the lowest levels of depressive symptoms.Hierarchical linear regression analysis yielded several significant findings:Higher levels of social engagement were significantly associated with fewer depressive symptoms(t=-7.932,P<0.001,B=-0.463).Marital status was a significant factor;married individuals reported fewer depressive symptoms compared to their unmarried counterparts(t=-6.368,P<0.001,B=-0.750).There was a significant moderating effect of marital status on the relationship between social engagement and depressive symptoms(t=-2.092,P=0.037,B=-0.217).Conclusion This study demonstrates that,among Chinese older adults,both social engagement and marital status significantly influence depressive symptoms.Higher social engagement,particularly in other activities like doing household chores,gardening,reading newspapers or books,and playing cards or Mahjong,is associated with fewer depressive symptoms,especially among married individuals.

Moderating Effect of Perceived Threat of Breast Cancer on Relation between Knowledge and Breast Self Examination

Estimated at more than 2.2 million cases worldwide,most breast cancer cases and deaths from breast cancer occur in low and middle-income countries.In Cameroon,many studies have underlined the effect of knowledge of breast cancer on screening measures such as self-examination and,to a lesser extent,the perception of the threat of this disease.This research aims to assess according to the Health Belief Model(HBM),the moderating effect of perceived threat of breast cancer on the relation between knowledge and breast self-examination.A questionnaire survey was conducted among 517 Cameroonian women to assess their general knowledge about breast cancer(risk factors and screening measures),their level of the perceived threat of breast cancer through Perceived susceptibility and severity,and the prevalence of breast self-examination amongst them.A regression analysis using the Macro Process for moderation indicates the main effect of Perceived threat(b=0,29;t(517)=2,36;p=0,02)of breast cancer and knowledge(b=0,02;t(517)=4,29;p<0,001)on breast self-examination.Results also confirm that the perceived threat of breast cancer moderates the effect of knowledge on breast self-examination.While the low level of perceived threat highlights the effect of knowledge on breast self-examination(b=0,02;t(517)=3,49;p<0,001),the high level of perceived threat cancels that effect(b=0,01;t(517)=1,97;p=0,01).A woman who perceives severity and susceptibility to breast cancer is more inclined to perform breast self-examination.This result suggests the importance of taking into account,in a context where knowledge of breast cancer is limited,relevant factors of the health belief model in preventive measures against breast cancer in general and the practice of breast self-examination in particular.

The Mediating and Moderating Effects of Family Resilience on the Relationship between Individual Resilience and Depression in Patients with Breast Cancer

Objective:This study evaluated the effect of resilience on depression among patients with breast cancer from individual and familial perspectives by exploring the mediating and moderating effects of family resilience between individual resilience and depression.Methods:A questionnaire survey was conducted among 337 patients with breast cancer who were admitted to the Oncology Department of Jiangsu Province Hospital.The survey included demographic information,the Connor–Davidson Resilience Scale(CD-RISC),the Family Resilience Assessment Scale(FRAS),and the Chinese version of the Patient Health Questionnaire-9(PHQ-9)for Depression.The relationship among individual resilience,family resilience,and depression was analyzed using hierarchical regression and bootstrap test to assess the mediating and moderating effects of family resilience.Results:The depression scores were(13.50±5.16),the individual resilience scores were(48.62±17.50),and the family resilience scores were(105.98±24.35).Significant differences in depression scores were observed in terms of family monthly income,average weekly exercise before diagnosis,post-diagnosis interpersonal relationship quality,and overall sleep quality in the past month(p<0.05).Patients with lower individual resilience had significantly higher depression scores than those with higher resilience(F=24.314,p<0.001),and similarly,patients with lower family resilience had higher depression scores than those with higher family resilience(F=41.660,p<0.001).Individual resilience and family resilience were significantly negatively correlated with depression(r=-0.447 and-0.441,respectively,p<0.001).Hierarchical regression analysis and bootstrap test showed that family resilience(β=-0.310,p<0.001)had a partial mediating effect between individual resilience(β=-0.321,p<0.001)and depression.The indirect effect size was-0.038,the 95%CI was(-0.056,-0.020),and the direct effect ratio was 71.43%.The interaction of family resilience and individual resilience had a moderating effect on depression(B=0.166,p<0.001).Family resilience negatively moderated the relationship between individual resilience and depressive symptoms and enhanced the protective effect of individual resilience against depression with increasing family resilience.Conclusion:Family resilience has mediating and moderating effects between individual resilience and depression in patients with breast cancer.

Effect of Dendrobium nobile powder combined with conventional therapy on mild to moderate fatty liver

BACKGROUND Nonalcoholic fatty liver disease(NAFLD)encompasses a variety of liver conditions impacting individuals who consume minimal or no alcohol.Recently,traditional Chinese medicine has been gradually used to treat mild to moderate fatty liver,among which Dendrobium nobile Lindl.powder has been affirmed by many doctors and patients to be effective.However,there is limited research on combining this treatment with standard therapies for mild to moderate NAFLD.AIM To survey the effect of combining Dendrobium nobile Lindl.powder with standard treatment on liver function and lipid metabolism disorder in patients with mild to moderate NAFLD.METHODS Eighty patients with mild to moderate NAFLD participated in this retrospective study,classified into two groups:The observation group(n=40)and the control group(n=40).In November 2020 and November 2022,the study was conducted at People’s Hospital of Chongqing Liang Jiang New Area.The control group received standard treatment,while the observation group received Dendrobium nobile Lindl.powder based on the control group.The study compared differences in traditional Chinese medicine clinical syndrome scores,liver fibrosis treatment,liver function indicators,lipid levels,and serum inflammatory factor levels before and after treatment,and we calculated the incidence of adverse reactions for both groups.RESULTS The total effective rate was 97.50%in the observation group and 72.5%in the control group.After 8 weeks of treatment,the main and secondary symptom scores remarkably decreased,especially in the observation group(P<0.05),and there was a significant reduction in the serum levels of hyaluronic acid(HA),laminin(LN),human rocollagen III(PC III),and collagen type IV(CIV).The levels of HA,LN,PC III,and CIV were significantly lower in the observation group(P<0.05).After 8 weeks,both groups indicated remarkable improvements in liver function and blood lipid levels,with the observation group having even lower levels(P<0.05).Serum levels of interleukin-1β,tumor necrosis factor-α,and interleukin-8 also dropped significantly.The observation group had a lower rate of adverse reactions(5.00%)compared to the control group(22.50%).CONCLUSION Adding Dendrobium nobile Lindl.powder to standard treatment has been found to remarkably improve symptoms and reduce inflammation in patients with mild to moderate fatty liver disease.It also enhances hepatic function and lipid profile,ameliorates liver fibrosis indices,and lowers the risk of side effects.Consequently,this therapeutic protocol shows promise for clinical implementation and dissemination.

The Impact of Sleep Determination on Procrastination before Bedtime:The Role of Anxiety

Objective:The importance of good sleep for energy recovery and overall physical and mental health cannot be overstated.However,the increasing competitiveness of society,diversifying lifestyles,and the rapid spread of the internet and electronic devices have significantly impacted people’s sleep patterns,particularly through bedtime procrastination.Therefore,this study aims to investigate the relationship and underlying mechanisms between sleep determination,anxiety,and bedtime procrastination among the Chinese population.Method:The study utilized data from a national survey—the China Residents’Sleep Condition Survey(November 2021,with 6,037 participants).By constructing mediation and moderation models,it analyzed the relationship and mechanisms between sleep determination and bedtime procrastination,highlighting the dual role of anxiety:as a mediator between sleep determination and bedtime procrastination,and as a moderator of their relationship.Results:There was a negative correlation between sleep determination and bedtime procrastination;anxiety was related to an increase in bedtime procrastination behaviors;In the interplay between sleep determination and pre-bedtime procrastination,the regulatory effect of anxiety is found to be more pronounced than its intermediary role,with anxiety significantly diminishing the inverse relationship between sleep determination and procrastination before bedtime.Conclusion:Bedtime procrastination can lead to sleep issues,thus reducing sleep quality.Enhancing sleep determination or alleviating pre-sleep anxiety can help inhibit bedtime procrastination behaviors.Intervening and reducing bedtime procrastination is one of the effective measures to improve sleep quality.

Relation between Interparental Conflict and Non-Suicidal Self-Injury in Adolescents:Mediating Role of Alexithymia and Moderating Role of Resilience

Background:Adolescents frequently engage in Non-Suicidal Self-Injury(NSSI),with recent trends indicating an increase in this behavior.At the same time,Chinese adolescents have a higher incidence of NSSI than Western adolescents.Therefore,it is necessary to explore the relationship between interparental conflict and NSSI among adolescents within the context of Chinese families.Methods:The research sample comprised 755 senior high school students(46.62%male;age M=16.82,SD=0.94 years)who completed the Interparental Conflict Child Perception Scale(CPIC),Adolescent Self-Injury Behavior Questionnaire(ASHS),Toronto Alexithymia Scale-20(TAS-20),and Scale of Adolescent Resilience(RSCA).Results:Findings suggest that interparental conflict is a significant positive predictor of NSSI(r=0.22,p<0.01).Alexithymia mediates the relation between interparental conflict and NSSI(effect size=0.09,95%CI[0.05,0.13]).Additionally,resilience moderates both the direct relation(β=−0.08,p<0.05)and the latter half of the mediating pathway(β=−0.08,p<0.05)in the moderated mediation model.Conclusion:This study indicates that interparental conflict have an impact on adolescents’NSSI in Chinese families,and alexithymia and resilience play important roles in the relationship.These findings offer valuable guidance for the prevention and intervention efforts targeting NSSI among adolescents in China and in similar family contexts.

Empowerment Mechanisms and Empirical Evidence of Payment Technology in Capacity Expansion and Quality Improvement of Residents’Consumption

The time-varying difference-in-difference model is used to identify the impact of payment technology on residents’consumption,and the moderation effect analysis method is used to identify its mechanism.It is found that payment technology promotes consumption capacity expansion and quality improvement(CEQI)through three pathways of alleviating liquidity constraints,reducing transaction costs and weakening the payment of pain.The parallel and serial mechanisms of the three are further explored.The effect of payment technology on the CEQI of residents’consumption shows obvious heterogeneity due to differences in urban and rural household registration and financial literacy.Based on the empirical research results and the national conditions of China,targeted policy recommendations are proposed from the demand side,the supply side and the technological side.

Parental Psychological Control and Internet Gaming Disorder Tendency:A Moderated Mediation Model of Core Self-Evaluation and Intentional Self-Regulation

Internet gaming disorder(IGD)among junior high school students is an increasingly prominent mental health concern.It is important to look for influences behind internet gaming disorder tendency(IGDT)in the junior high school student population.The present study aimed to reveal the explanatory mechanisms underlying the association between parental psychological control(PPC)and internet gaming disorder tendency among junior high school students by testing the mediating role of core self-evaluation(CSE)and the moderating role of intentional self-regulation(ISR).Participants in present study were 735 Chinese junior high school students who completed offline self-report questionnaires on parental psychological control,core self-evaluation,intentional self-regulation,and Internet gaming disorder tendency.Analyses were conducted via mediation and moderated mediation.The results showed that:(1)Parental psychological control was positively related to junior high school students’Internet gaming disorder tendency.Core self-evaluation,and intentional self-regulation were negatively related to junior high school students’Internet gaming disorder tendency,respectively.(2)Core self-evaluation partially mediated the relationship between parental psychological control and junior high school students’Internet gaming disorder tendency.(3)Intentional self-regulation moderated the association between parental psychological control and Internet gaming disorder tendency,as well as the relationships between parental psychological control and core self-evaluation and core self-evaluation and Internet gaming disorder tendency in the mediated model.Based on these findings,we believe that there is a need to weaken parental psychological control,strengthen junior high school students’core self-evaluation and intentional self-regulation,and to recognize the important role of parents as well as their children’s personal positive traits in the healthy development of junior high school students.

The Moderating Effect of Organizational Identification on Occupational Stress and Insomnia Among Nurses

Objective:To explore the relationship between organizational identification,occupational stress,and insomnia among nurses and to analyze the moderating role of organizational identification between occupational stress and insomnia.Methods:Through stratified sampling,720 nurses working in a tertiary A-level hospital in Shandong Province from March to May 2021 were surveyed using an effort-reward imbalance questionnaire,an organizational identification questionnaire,and the Athens Insomnia scale.Results:Organizational identification was negatively correlated with occupational stress and insomnia(r_(1)=-0.121,P_(1)<0.01;r_(2)=-0.144,P_(2)<0.01).Occupational stress was positively correlated with insomnia(r=0.379,P<0.01).Organizational identity significantly moderated nurses’occupational stress and insomnia(β=-0.192,t=-2.558,P<0.05).Conclusion:Occupational stress and organizational identification can predict insomnia.Organizational identification could negatively mediate the relationship between occupational stress and insomnia.Improving organizational identification may help alleviate insomnia symptoms by relieving occupational stress.

Analysis of Influencing Factors of Moderate to Severe Malnutrition in Elderly Patients with Lung Cancer during Chemotherapy

Objective:This study aims to identify the factors influencing moderate to severe malnutrition in elderly lung cancer patients undergoing chemotherapy and to provide a basis for developing clinical prevention and intervention strategies.Methods:The clinical data of 150 elderly lung cancer patients who received chemotherapy were retrospectively analyzed.Demographic data,clinical characteristics,laboratory indicators,treatment plans,and other relevant information were collected.Independent risk factors for moderate to severe malnutrition during chemotherapy were identified.Results:During chemotherapy,50 patients(33.33%)developed moderate to severe malnutrition.The BMI of patients with moderate to severe malnutrition was significantly lower than that of patients with no or mild malnutrition(21.20±1.60 vs.26.14±2.31,P<0.001),and the proportion of patients with stage IV tumors was significantly higher(60.00%vs.27.00%,P<0.001).Serum pre-albumin(pre-ALB)and hemoglobin(Hb)levels in patients with moderate to severe malnutrition were significantly lower than those in patients with no or mild malnutrition(152.67±30.41 g/L vs.252.47±51.24 g/L and 102.44±10.09 g/L vs.154.21±15.18 g/L,respectively,P<0.001 for all).Conclusion:Low BMI,decreased serum pre-ALB levels,and decreased serum Hb levels before chemotherapy are independent risk factors for moderate to severe malnutrition in elderly lung cancer patients during chemotherapy.Close clinical attention should be given to these patients,with early intervention measures such as nutritional support to reduce the incidence of malnutrition and improve patients’quality of life and prognosis.

应用MODIS数据反演青藏高原地区地表反照率

应用RossThick-LiTransit核驱动BRDF(bidirectional reflectance distribution function)模型,选择2004年Terra MODIS(moderate resolution imaging spectraradiometer)500 m分辨率数据,对青藏高原地区的地表反照率进行了反演研究,并以平均气溶胶光学厚度值0.11计算了正午时(北京时间12:00)实际的地表反照率,反演结果与当地的地表覆盖类型和地形具有较好的一致性。此外,藏北高原4个辐射观测站点观测资料与反演结果的比较表明,500 m分辨率反演结果不仅可以满足气候和陆面过程模式的精度要求,而且精度高于美国1 km分辨率反照率反演结果。

Optimization of copper extraction for bioleaching of complex Cu-polymetallic concentrate by moderate thermophiles

Effects of initial pH, temperature, liquid volume, rotation speed, galvanic interaction （pyrite ratio） and pulp density on bioleaching of complex Cu-polymetallic concentrate were investigated. The results indicated that the copper extraction at pH 1.5 was 1.5 and 1.4 times that at pH 1.0 and pH 2.0 respectively. The copper extraction obtained at 45 ℃ was 1236.8%higher than that at 50 ℃. With the increase of rotation speed or the decrease of liquid volume, copper extraction was improved obviously. Copper extraction was improved gradually with the increase of pyrite ratio. However, when the ratio was higher than 20.0%, no further increase in copper extraction was observed. And the statistically significant interactive effects on copper extraction were found between temperature and pH, and temperature and pyrite ratio.

Surface species of chalcopyrite during bioleaching by moderately thermophilic bacteria

X-ray diffraction （XRD） and X-ray photoelectron spectroscopy （XPS） analyses were carried out to investigate the surface species and interfacial reactions during bioleaching of chalcopyrite by different strains of moderately thermophilic bacteria （45 °C）. Results show that monosulfide （CuS）, disulfide （S22？）, polysulfide （Sn2？）, elemental sulfur （S0） and sulfate （SO42？） are the main intermediate species on the surface of chalcopyrite during bioleaching byA. caldus,S. thermosulfidooxidans andL. ferriphilum. The low kinetics of dissolution of chalcopyrite inA. caldus can be mainly attributed to the incomplete dissolution of chalcopyrite and the passivation layer of polysulfide. Polysulfide and jarosite should be mainly responsible for the passivation of chalcopyrite in bioleaching byL. ferriphilumorS. thermosulfidooxidans. However, elemental sulfur should not be the main composition of passivation layer of chalcopyrite during bioleaching.

烟台四十里湾叶绿素a浓度的时空分布特征及其影响机制

本文利用2003～2012年MODIS（Moderate Resolution Imaging Spectrometer）卫星遥感数据,分析了四十里湾叶绿素a浓度的时空分布特征,并探讨其影响机制。结果表明,四十里湾叶绿素a浓度具有显著的时空分布特征。从空间分布来看,全年均是南部近岸较高,从西南的湾内向东北的湾外逐渐降低。逛荡河口正北约6 km海域在4～5、7～9月出现叶绿素a高值羽。从时间分布来看,四十里湾叶绿素a浓度夏季最高,春秋次之,冬季最低,5月份和8月份出现峰值,呈现温带海域特有的＂双峰＂特性。四十里湾年平均叶绿素a浓度呈现波动状态,波动范围约为6～12 mg/m3。四十里湾叶绿素a浓度的分布及变化与海表面温度成正相关,相关系数是0.41。另外,入海排污和海水养殖业等人类活动可能也是影响四十里湾叶绿素a浓度时空变化的重要因素。

FINITE ELEMENT MODELING OF MODERATELY THICK COMPOSITE PLATE WITH PIEZOELECTRIC SENSORS AND ACTUATORS

A rectangular finite element for laminated plate with bonded and/or embedded piezoelectric sensors and actuators is developed based on the variational principle and the first order shear deformation theory. The element has four-node, 20-degrees-of-freedom with one potential degree of freedom for each piezoelectric layer to represent the piezoelectric behavior. The higher order derivation of deflection is obtained by using the normal rotation expressions to take the effects of transverse shear deformation into considerations. The finite element can accurately simulate the deformation of both thin and moderately thick plates. A Fortran program is written and a number of benchmark tests are exercised to verify its effectiveness. Results are compared well with the existing data. The unbalanced composite with piezoelectric layers is then analyzed by using the model. Results show that the changes of the ratio between the thickness of positive angle layers and the negative angle layers have an effect on the deformation of the structure under the same electric loading.

天地图·河南影像数据关键技术研究

天地图·河南是"天地图"的有机组成部分保质保量实现天地图.河南影像数据一年更新两次目标,需要研究如何快速处理影像数据,提高工作效率,有必要从软件与硬件应用两个方面探讨影像数据处理关键技术。

Relationship between Pepper Cultivars' Yields and High Temperatures with Pepper in Different Genotypes

[Objective] The aim was to research effects of high temperature stress on pepper yield by cultivation of peppers in different genotypes and provide theoretical references for pepper breeding and high-yield cultivation. [Method] Four pepper va- rieties were studied with varied genotypes to explore effects of temperatures on pepper fruiting and yield in the whole growth stage. [Result] The optimal-temperatre term for pepper blooming and fruiting were shorter. For example, the periods from June 16 to July 15 and from August 16 to September 15 would be the best, with temperature ranging from 20.70 ℃ to 30.74 ℃. In the stage from July 16 to August 15, the temperature range of 24.22 ℃-32.17 ℃ would severely affect pepper growth and yield. Pepper No. 1 and pepper No. 1-1＇s yields were just 38.21% and 51.74% of the yields in the stage 1st and 52.01% and 62.35% in the stage 3rd and eady No. 1 and late No. 1 were 48.1% and 72.38%, respectively. Under high tem- perature stress in summer, pepper No. 1, pepper No. 1-1, and late No. 1 showed extremely significant differences with early No. 1 （P〈0.01）. The yield ratios of pep- per No. 1 and pepper No. 1-1 in stage 1st （May 25-July 15） and the later three stages were 42.34：57.66 and 39.50：60.50; the ratio was 47.99：52.21 of early No. 1; the ratio of late No. 1 was 20.25：79.75. [Conclusion] The cultivation approaches should vary upon pepper variety, necessitating the focus on pepper management, fertilization, and irrigation, and locating peak-blooming term in moderate-temperature stage to accelerate pepper growth.