Background Severe aortic regurgitation is a rare clinical presentation of Behcet's disease,but the valve detachment after valve replacement presents challenges to cardiac surgeons.Methods Five patients with prostheti...Background Severe aortic regurgitation is a rare clinical presentation of Behcet's disease,but the valve detachment after valve replacement presents challenges to cardiac surgeons.Methods Five patients with prosthetic detachment after aortic valve replacement attributable to Behcet's disease were surgically treated between January 2007 and December 2010.These 5 patients (all male) were from 24 to 50 years of age (mean,38.8 ± 9.8).Mean follow-up duration from index operations was 19.2 ± 12.5 months (range,3-36 months).Results There was no early death and pseudoaneurysm of the aortic root occurred at index operations.But one patient suffered Ⅲ° AVB and had pacemaker implanted.All the patients were administered immunosuppressive therapies after operation.Conclusion Modified Bentall operation and postoperative immunosuppressive therapy may be helpful for the patients with valve detachment after valve surgery due to Behcet's disease.展开更多
文摘Background Severe aortic regurgitation is a rare clinical presentation of Behcet's disease,but the valve detachment after valve replacement presents challenges to cardiac surgeons.Methods Five patients with prosthetic detachment after aortic valve replacement attributable to Behcet's disease were surgically treated between January 2007 and December 2010.These 5 patients (all male) were from 24 to 50 years of age (mean,38.8 ± 9.8).Mean follow-up duration from index operations was 19.2 ± 12.5 months (range,3-36 months).Results There was no early death and pseudoaneurysm of the aortic root occurred at index operations.But one patient suffered Ⅲ° AVB and had pacemaker implanted.All the patients were administered immunosuppressive therapies after operation.Conclusion Modified Bentall operation and postoperative immunosuppressive therapy may be helpful for the patients with valve detachment after valve surgery due to Behcet's disease.