Review on Development and Application of Fabric Electrodes in Electrocardiogram Monitoring Garments

Cardiovascular disease persists as the primary cause of human mortality,significantly impacting healthy life expectancy.The routine electrocardiogram(ECG)stands out as a pivotal noninvasive diagnostic tool for identifying arrhythmias.The evolving landscape of fabric electrodes,specifically designed for the prolonged monitoring of human ECG signals,is the focus of this research.Adhering to the preferred reporting items for systematic reviews and meta-analyses(PRISMA)statement and assimilating data from 81 pertinent studies sourced from reputable databases,the research conducts a comprehensive systematic review and meta-analysis on the materials,fabric structures and preparation methods of fabric electrodes in the existing literature.It provides a nuanced assessment of the advantages and disadvantages of diverse textile materials and structures,elucidating their impacts on the stability of biomonitoring signals.Furthermore,the study outlines current developmental constraints and future trajectories for fabric electrodes.These insights could serve as essential guidance for ECG monitoring system designers,aiding them in the selection of materials that optimize the measurement of biopotential signals.

Semi-implantable device based on multiplexed microfilament electrode cluster for continuous monitoring of physiological ions

Modern medicine is increasingly interested in advanced sensors to detect and analyze biochemical indicators.Ion sensors based on potentiometric methods are a promising platform for monitoring physiological ions in biological subjects.Current semi-implantable devices are mainly based on single-parameter detection.Miniaturized semi-implantable electrodes for multiparameter sensing have more restrictions on the electrode size due to biocompatibility considerations,but reducing the electrode surface area could potentially limit electrode sensitivity.This study developed a semi-implantable device system comprising a multiplexed microfilament electrode cluster(MMEC)and a printed circuit board for real-time monitoring of intra-tissue K^(+),Ca^(2+),and Na^(+)concentrations.The electrode surface area was less important for the potentiometric sensing mechanism,suggesting the feasibility of using a tiny fiber-like electrode for potentiometric sensing.The MMEC device exhibited a broad linear response(K^(+):2–32 mmol/L;Ca^(2+):0.5–4 mmol/L;Na^(+):10–160 mmol/L),high sensitivity(about 20–45 mV/decade),temporal stability(>2weeks),and good selectivity(>80%)for the above ions.In vitro detection and in vivo subcutaneous and brain experiment results showed that the MMEC system exhibits good multi-ion monitoring performance in several complex environments.This work provides a platform for the continuous real-time monitoring of ion fluctuations in different situations and has implications for developing smart sensors to monitor human health.

Epidural Blood Patches Performed with Miethke Sensor Reservoir for Continuous Intracranial Pressure Monitoring

An epidural blood patch (EBP) is a procedure performed by injecting autologous blood into a patient’s epidural space, usually at the site of a suspected CSF leak. It is typically performed in patients with characteristic postural headaches due to low intracranial pressure. We report a case of a young female with an implanted Miethke Sensor Reservoir, which was used for continuous intracranial pressure (ICP) monitoring during a two-level epidural blood patch. ICP increased only with thoracic injection, suggesting thoracic EBP may have greater efficacy than lumbar EBP in treating SIH and PDPH when the site of CSF leak is unknown.

Preparation and Properties of Embeddable Ag/Ag Cl Gelling Reference Electrode for Rebars Corrosion Monitoring in Concrete

Reference electrodes are a key part for corrosion monitoring and measurement of rebars in concrete. A reference electrode that can be buried in concrete is fabricated by using Ag/Ag Cl electrode and methyl cellulose gelling electrolyte. The stability, repeatability and anti-polarization of the reference electrode are investigated; the influences of the inner electrolyte loss, exterior OH- contamination, and temperature on the potential of the reference electrode are also investigated in this paper. The results show that the reference electrode has good stability, repeatability, and antipolarization. The influences of inner electrolyte loss, exterior OH- contamination, and temperature on the potential of the reference electrode are minimal. Therefore, it can be used for corrosion monitoring and measurement of rebars in concrete.

Evaluation of Pencil Lead Based Electrodes for Electrocardiogram Monitoring in Hot Spring

Electrocardiogram(ECG)electrodes are conductive pads applied to the skin to measure cardiac activity.Ag/AgCl electrodes are the commercial product which widely used to obtain ECGs.When monitoring the ECG in a hot spring,Ag/AgCl electrodes must be waterproofed;however,this is time-consuming,and the adhesive may tear the skin on removal.For solving the problem,we developed the carbon pencil lead(CPL)electrodes for use in hot springs.Both CPL and Ag/AgCl electrodes were connected to ECG100C’s cables.The Performance was evaluated in three conditions as following:hot spring water with and without bubble,and in cold water.In each environment,the procedure was followed by three different protocols that are recording from the dry condition,hot spring water immersion with and without movement,post hot spring water condition.Under dry and wet conditions,both electrodes can obtain the waveform of the ECG signal in which all PQRST waves were identifiable.Nevertheless,the signal quality of both types of electrodes was different in water immersion with and without movement.The overall morphology obtained by Ag/AgCl electrodes was unstable higher than that of CPL electrodes in immersion without movement condition.The CPL electrodes provided better ECG waveform quality compared to Ag/AgCl electrodes in which the ECG signal had high waveforms distortion in water immersion with movement condition.

New solid state phosphate sensitive electrodes for routine environmental monitoring

Highly selective and sensitive phosphate sensors have been fabricated by constructing a solid membrane disk consisting of variable mixtures of aluminium powder (Al), aluminium phosphate (AlPO4) and powdered copper (Cu). Both binary and ternary electrode systems are produced. The ternary membranes exhibit greater selectivity over a wide range of concentrations. The ternary electrode with the composition 25% AlPO4, 25% Cu and 50% Al was selected as our preferred electrode. The newly fabricated ternary membrane phosphate selective electrodes exhibited linear potential response in the concentration range of 1.0?×?10?1 to 1.0?×?10?6?mol?L?1. The electrodes also exhibit a fast response time of <60?s. Their detection limit is lower than 1.0?×?10?6?mol?L?1. The unique feature of the described electrodes is their ability to maintain a steady and reproducible response in the absence of an ionic strength control. The electrodes have a long lifetime and can be stored in air when not in use.

Design of On-Line Monitoring System for UHVDC Earth Electrode

At present the detecting of ultra high voltage direct current (UHVDC) earth electrode frequently uses manual inspection. This method can't get the real-time operational data of the earth electrodes, and meanwhile, the labor cost is very high. In order to satisfy the security needs of UHVDC, this paper designs an on-line monitoring system for UHVDC earth electrode. By 3G wireless communication-technologies, the system can monitor remotely many kinds of data such as the value of the grounding current, water level of the observation well, soil temperature and humidity near the earth electrode, the micro-climate around the earth electrode site, video data, etc. Through analyzing the datum, the system has broad prospect on fault detection and life evaluation of the UHVDC earth electrode.

Interventional therapy for intracranial aneurysms under neuroelectrophysiological monitoring

Objective To study the application of neuroelectrophysiological monitoring for interventional therapy of intracranial aneurysms. Methods 22 patients with intracranial aneurysm underwent neuroelectrophysiological monitoring during interventional therapy. Somatosensory evoked potential( SSEP) ,brainstem

Flexible and Stretchable Electrodes for In Vivo Electrophysiological and Electrochemical Monitoring

In vivo monitoring of bioelectrical and biochemical signals with implanted electrodes has received great interest over the past decades.However,this faces huge challenges because of the severe mechanical mismatch between conventional rigid electrodes and soft biological tissues.In recent years,the emergence of flexible and stretchable electrodes offers seamless and conformable biological-electronic interfaces and has demonstrated significant advantages for in vivo electrochemical and electrophysiological monitoring.This review first summarizes the strategies for electrode fabrication from the point of substrate and conductive materials.Next,recent progress in electrode functionalization for improved performance is presented.Then,the advances of flexible and stretchable electrodes in exploring bioelectrical and biochemical signals are introduced.Finally,we present some challenges and perspectives ranging from electrode fabrication to application.

Monitoring Biosignals with Low Cost Wearable Sensors

With the increase of aging population, we have been witnessing a decline in the quality of life influenced by numerous social, cultural and economic factors. Several studies have addressed these facts and some emerging technologies are capable of monitoring and anticipating these problems. With the advance in the development of smart textiles, it＇s possible to use these technologies in the acquisition of biosignals, which allows obtaining a better comfort regarding the use of smart clothes over traditional Ag/AgCI electrodes. In this way, it is possible to monitor for longer periods reducing the discomfort to the user. This paper reports the development of a low cost sensor with the capability of monitoring the electrical activity of the heart, measuring the heart rate and body temperature and is applied in the scenario： health ＆ wellbeing, targeting the continuous measurement of vital signs.

Monitoring Domoic Acid in Marine Phytoplankton by Disposable Immunosensors

Advances in sensor technology have allowed the significant progress in the monitoring of noxious compounds in the sea, providing real-time detection so as to prevent risks associated with the diffusion and dispersion of toxic substances in the environment. An important element in the overall picture is the harmful algal blooms which pose serious threats to marine ecosystems through the production of toxins that accumulate in filter-feeders and ultimately impact both human health and fisheries. Domoic acid is a neurotoxic amino acid produced by marine planktonic diatoms of the genus Pseudo-nitzschia. Here we monitored domoic acid production by natural Pseudo-nitzschia populations in phytoplankton samples collected along the Middle Tyrrhenian coast, over the course of one year, using selective immunosensors based on screenprinted electrodes, using differential pulse voltammetry as the electrochemical technique, to yield quantitative outputs. In this work, disposable devices have been applied for monitoring the production of domoic acid on algal extracts and the results have been validated by conventional high pressure liquid chromatography-ultraviolet detection methods. The data obtained revealed the presence of domoic acid in Italian phytoplankton, especially in coastal impacted areas, highlighting the potential risk of toxin entering into marine food webs and the environment. Immunosensors based on screen-printed electrodes prove to be effective tools for annual monitoring of domoic acid in seawater samples, thus providing a reliable early warning system relative to health and economic impact of algal toxins.

Development of Portable Monitoring System for Real-Time Detection of Fetal Movement

Effective fetal monitoring is an important guarantee for fetal health and early treatment. Fetal movement is one of critical indicators of fetal monitoring, which plays an important role in fetal health. Counting the number of fetal movement by pregnant women is a traditional method for long-term monitoring. However, there are many defects in pregnant women’s feeling count, which cannot meet the accurate requirements of modern perinatal medicine. With the rapid development of biological and electronic technology, various sensors are used to probe the fetal dynamic monitoring, but not on fetal movement. This research proposes a monitoring method for fetal movement via three electrodes. Briefly: first, three electrodes are used to extract electrical signals in the abdomen of pregnant women;second, these signals are amplified and filtered;third, A/D converter with microprocessor is used to make analog digital conversion, which can be stored in the SD card under the control of the microprocessor;finally, the SD card data are processed by computer software and the fetal movement information is analyzed.

The Calibration and Use of a New Ring-Shaped Ionization Chamber for Monitoring and Dosimetry of X-Ray Beams

Today, dosimeters are used generally for dosimetry of the diagnostic X-ray beam. Ionization chambers are appropriate instruments for monitoring and also the dosimetry of X-ray beam in medical diagnostic equipment. The present work introduces design and investigation of a new ring-shaped monitor chamber with a PMMA body, graphite-coated PMMA windows (0.5 mm thick), a special graphite-foil central electrode (0.1 mm thick, 0.7 g/cm3 dense) that creating two sensitive volumes and a central hole for crossing the radiation beam with less attenuation. The results of performance tests conducted at the Nuclear Science and Technology Research Institute, AEOI in Karaj- Iran proved the high short and long-term stability, the very low leakage current, the low directional dependence and very high ion collection efficiency through the special design of the collecting electrode. Moreover, the FLUKA Monte Carlo simulations certified the negligible effect of central electrode on this new ring-shaped monitor chamber. According to the results of the performance tests, the new monitor chamber can be used as a standard dosimeter in order to monitor X-ray beam in primary standard dosimetry laboratories.

Porous fiber paper and 3D patterned electrodes composed high-sensitivity flexible piezoresistive sensor for physiological signal monitoring

The research on flexible pressure sensors has drawn widespread attention in recent years,especially in the fields of health care and intelligent robots.In practical applications,the sensitivity of sensors directly affects the precision and integrity of weak pressure signals.Here,a pressure sensor with high sensitivity and a wide measurement range composed of porous fiber paper and 3D patterned electrodes is proposed.Multi-walled carbon nanotubes with excellent conductivity were evenly sprayed on the fiber paper to form the natural spatial conducting networks,while the copper-deposited polydimethylsiloxane films with micropyramids array were used as electrodes and flexible substrates.Increased conducting paths between electrodes and fibers can be obtained when high-density micro-pyramids fall into the porous structures of the fiber paper under external pressure,thereby promoting the pressure sensor to show an ultra-high sensitivity of 17.65 kPa^(-1)in the pressure range of 0–2 kPa,16 times that of the device without patterned electrodes.Besides,the sensor retains a high sensitivity of 2.06 kPa^(-1)in an ultra-wide measurement range of 150 kPa.Moreover,the sensor can detect various physiological signals,including pulse and voice,while attached to the human skin.This work provides a novel strategy to significantly improve the sensitivity and measurement range of flexible pressure sensors,as well as demonstrates attractive applications in physiological signal monitoring.

Smart epidermal electrophysiological electrodes:Materials,structures,and algorithms

Epidermal electrophysiological monitoring has garnered significant attention for its potential in medical diagnosis and healthcare,particularly in continuous signal recording.However,simultaneously satisfying skin compliance,mechanical properties,environmental adaptation,and biocompatibility to avoid signal attenuation and motion artifacts is challenging,and accurate physiological feature extraction necessitates effective signal-processing algorithms.This review presents the latest advancements in smart electrodes for epidermal electrophysiological monitoring,focusing on materials,structures,and algorithms.First,smart materials incorporating self-adhesion,self-healing,and self-sensing functions offer promising solutions for long-term monitoring.Second,smart meso-structures,together with micro/nanostructures endowed the electrodes with self-adaption and multifunctionality.Third,intelligent algorithms give smart electrodes a“soul,”facilitating faster and more-accurate identification of required information via automatic processing of collected electrical signals.Finally,the existing challenges and future opportunities for developing smart electrodes are discussed.Recognized as a crucial direction for next-generation epidermal electrodes,intelligence holds the potential for extensive,effective,and transformative applications in the future.

Optic nerve sheath diameters in nontraumatic brain injury:A scoping review and role in the intensive care unit

BACKGROUND Neuromonitoring in medical intensive care units is challenging as most patients are unfit for invasive intracranial pressure(ICP)modalities or unstable to transport for imaging.Ultrasonography-based optic nerve sheath diameter(ONSD)is an attractive option as it is reliable,repeatable and easily performed at the bedside.It has been sufficiently validated in traumatic brain injury(TBI)to be incorporated into the guidelines.However,currently the data for non-TBI patients is inconsistent for a scientific recommendation to be made.AIM To compile the existing evidence for understanding the scope of ONSD in measuring ICP in adult non-traumatic neuro-critical patients.METHODS PubMed,Google Scholar and research citation analysis databases were searched for studies in adult patients with non-traumatic causes of raised ICP.Studies from 2010 to 2024 in English languages were included.RESULTS We found 37 articles relevant to our search.The cutoff for ONSD in predicting ICP varied from 4.1 to 6.3 mm.Most of the articles used cerebrospinal fluid opening pressure followed by raised ICP on computed tomography/magnetic resonance imaging as the comparator parameter.ONSD was also found to be a reliable outcome measure in cases of acute ischaemic stroke,intracerebral bleeding and intracranial infection.However,ONSD is of doubtful utility in septic metabolic encephalopathy,dysnatremias and aneurysmal subarachnoid haemorrhage.CONCLUSION ONSD is a useful tool for the diagnosis of raised ICP in non-traumatic neuro-critically ill patients and may also have a role in the prognostication of a subset of patients.

重型创伤性脑损伤去骨瓣减压应用改良Paine点穿刺监测脑室内颅内压的优势

目的探讨重型创伤性脑损伤(TBI)开颅去骨瓣减压术(DC)中应用改良Paine点穿刺行脑室内颅内压(ICP)监测探头置入的优势。方法回顾性分析2020年4月-2022年4月嘉兴市第二医院收治的48例重型TBI患者的临床资料。所有患者均行DC联合脑室内ICP监护术,按照ICP监测术式的不同,分为观察组(23例)与对照组(25例),其中观察组行DC切口内改良Paine点穿刺脑室内ICP监测探头置入术,对照组行传统DC对侧切口颅骨钻孔经Kocher点脑室内ICP监测探头置入术。比较两组术前一般资料、手术用时、术后甘露醇使用剂量及持续时间、ICP监测持续时间、术后再出血率、颅内感染率、术后3个月时格拉斯哥预后评分(GOS)。结果两组一般资料、甘露醇使用剂量、甘露醇持续时间和ICP监测持续时间比较差异均无统计学意义(P>0.05);观察组手术用时、术后再出血率、颅内感染率明显少于或低于对照组(P<0.05);两组术后3个月GOS评分比较差异无统计学意义(P>0.05)。结论相较传统的DC对侧切口颅骨钻孔经Kocher点行脑室内ICP监测探头置入术,重型脑外伤DC术中通过切口内改良Paine点穿刺行脑室内ICP监测探头置入术可缩短手术用时,降低术后再出血率、颅内感染率。

基于智能柔性织物传感器的漏尿频次监测系统研究

为诊断每位尿失禁患者的漏尿频次,治疗尿失禁问题,在尿片中嵌入织物功能电极,连接到自制的可穿戴式尿失禁患者漏尿频次监测系统,制备出智能尿片,根据功能电极电阻值的变化监测漏尿的频次。结果表明:每个功能电极连续监测次数可达15次以上,平均准确率达86.2%,灵敏度达73.5 kΩ/(0.1 mL)。该系统提出了一种尿失禁患者监测漏尿频次的简便方法,也可用于患者评估基本健康状况;同时也提供了一种智能柔性织物传感器的应用思路。

神经内镜血肿清除术联合颅内压监测在高血压脑出血患者中的应用效果分析

目的探讨神经内镜血肿清除术联合颅内压监测在高血压脑出血(HICH)患者中的应用效果。方法选取2018年1月至2022年1月四川省资阳市中心医院收治的64例HICH患者为研究对象,根据手术方式不同将研究对象分为对照组(给予神经内镜血肿清除术)和观察组(给予神经内镜血肿清除术联合颅内压监测),每组32例。比较分析两组患者的临床特征、围手术期相关指标。比较分析两组患者术后6个月的预后及并发症发生情况。结果两组患者的脑出血侧别、脑血肿体积、脑出血位置、中线偏移比较差异均无统计学意义(P>0.05)。观察组患者的血肿清除率高于对照组,甘露醇用量、出院时的Rankin量表评分、术后住院时间均低于或短于对照组,差异均有统计学意义(P<0.05)。两组患者术后6个月的并发症总发生率比较差异无统计学意义(P>0.05);观察组患者术后6个月的Rankin量表评分低于对照组,差异有统计学意义(P<0.05)。结论神经内镜血肿清除术联合颅内压监测可显著改善HICH患者的预后,且安全性较好。

中重度颅脑损伤颅内压波幅监测与甘露醇应用的关系及预后情况研究

目的探究中重度颅脑损伤患者颅内压波幅监测与甘露醇应用的关系及患者预后情况。方法选取中重度颅脑损伤患者80例,按随机数字表法将其分为2组,实验组和对照组,每组40例。对照组采用单纯监测颅内压,若患者单纯监测颅内压>22 mmHg则应用甘露醇,观察组采用平均颅内压波幅监测,若患者平均颅内压波幅(MWA)>5 mmHg则应用甘露醇。观察2组甘露醇应用总量、甘露醇应用时间、甘露醇相关并发症发生率及治疗后3个月预后情况。结果2组患者性别、年龄、格拉斯哥昏迷评分法(GCS)评分、损伤原因、出血部位等一般资料比较,差异无统计学意义(P>0.05)。观察组甘露醇应用总量、甘露醇应用时间均低于对照组,差异有统计学意义(P<0.05)。2组患者在急性肾衰竭、血容量不足、心律失常等并发症比较上,差异无统计学意义(P>0.05),但在高渗状态、电解质紊乱、静脉炎等并发症发生率上,观察组显著低于对照组,差异有统计学意义(P<0.05)。观察组预后良好率为75.00%,显著高于对照组的52.50%,差异有统计学意义(P<0.05)。结论中重度颅脑损伤患者采用平均颅内压波幅(MWA)监测并应用甘露醇治疗,在减少甘露醇应用总量、应用时间和甘露醇相关并发症的同时,可以提高预后良好率,具有一定的临床应用价值。