Rapid and accurate acquisition of soil organic matter(SOM)information in cultivated land is important for sustainable agricultural development and carbon balance management.This study proposed a novel approach to pred...Rapid and accurate acquisition of soil organic matter(SOM)information in cultivated land is important for sustainable agricultural development and carbon balance management.This study proposed a novel approach to predict SOM with high accuracy using multiyear synthetic remote sensing variables on a monthly scale.We obtained 12 monthly synthetic Sentinel-2 images covering the study area from 2016 to 2021 through the Google Earth Engine(GEE)platform,and reflectance bands and vegetation indices were extracted from these composite images.Then the random forest(RF),support vector machine(SVM)and gradient boosting regression tree(GBRT)models were tested to investigate the difference in SOM prediction accuracy under different combinations of monthly synthetic variables.Results showed that firstly,all monthly synthetic spectral bands of Sentinel-2 showed a significant correlation with SOM(P<0.05)for the months of January,March,April,October,and November.Secondly,in terms of single-monthly composite variables,the prediction accuracy was relatively poor,with the highest R^(2)value of 0.36 being observed in January.When monthly synthetic environmental variables were grouped in accordance with the four quarters of the year,the first quarter and the fourth quarter showed good performance,and any combination of three quarters was similar in estimation accuracy.The overall best performance was observed when all monthly synthetic variables were incorporated into the models.Thirdly,among the three models compared,the RF model was consistently more accurate than the SVM and GBRT models,achieving an R^(2)value of 0.56.Except for band 12 in December,the importance of the remaining bands did not exhibit significant differences.This research offers a new attempt to map SOM with high accuracy and fine spatial resolution based on monthly synthetic Sentinel-2 images.展开更多
Introduction: the problem of Severe Acute Malnutrition (SAM) and its consequences concern and challenge all social actors worldwide. The objective of the study was to identify the real obstacles that actors face in th...Introduction: the problem of Severe Acute Malnutrition (SAM) and its consequences concern and challenge all social actors worldwide. The objective of the study was to identify the real obstacles that actors face in the integrated management of children aged 6 - 59 months suffering from SAM at the University Hospital of Mother and Child (CHUME) and the Chad-China Friendship Hospital (HATC) of N’Djamena. Methodology: this is a cross-sectional descriptive and interpretative study conducted from January to October 2023 at the CHUME and HATC of N’Djamena. It is based on questionnaires and direct observation of two hundred and thirty-six (236) parents or guardians of malnourished children admitted to these health facilities. All 236 agreed to participate freely in this study. Results: it appears from this study that the obstacles to the integrated management of malnourished children were: poor care-care relationship (26.7%) permanent product breaks (22.9%), the direct costs of services ranged from 30,000 to 60,000 FCFA (41.53%), drugs used for the treatment of patients came from the street (66.10%), malaria and anemia occupy an important place (27.5%), 57.2% respondents had monthly income below 60,000 CFAF. Conclusion: the present study carried out has identified the real bottlenecks to the integrated management of children suffering from SAM in the therapeutic nutritional units of the city of N’Djamena. .展开更多
Introduction: Infant and child mortality is a worldwide concern, but developing countries such as Mali are more affected. The aim of this study was to investigate morbidity and factors associated with mortality in chi...Introduction: Infant and child mortality is a worldwide concern, but developing countries such as Mali are more affected. The aim of this study was to investigate morbidity and factors associated with mortality in children aged 1 month to 15 years. Methodology: This was a cross-sectional study which took place from January 1 to December 31, 2020 covering children aged 1 month to 15 years hospitalized at the Kalaban-Coro CSRéf. Data were entered into Excel and analyzed using SPSS version 20 software. Results: Five hundred children aged 1 months to 15 years were included. The age range 1 to 5 years (53.6%) and male sex (58.2%) were the most represented. Malaria (72.2%), acute respiratory infections (6.2%) and diarrhea/dehydration (3%) were the main morbidities. Mortality was estimated at 10.6%, and the two main causes of death were malaria (56.6%) and acute respiratory infections (7.54%). Univariate analysis revealed a statistically significant association between the dependent variable (death) and age (p Conclusion: This study confirms the high rate of infant and child morbidity and mortality in our health facilities. Strengthening human resources and intensifying behavior-change communication can help reverse the trend.展开更多
Copula functions have been widely used in stochastic simulation and prediction of streamflow.However,existing models are usually limited to single two-dimensional or three-dimensional copulas with the same bivariate b...Copula functions have been widely used in stochastic simulation and prediction of streamflow.However,existing models are usually limited to single two-dimensional or three-dimensional copulas with the same bivariate block for all months.To address this limitation,this study developed a mixed D-vine copula-based conditional quantile model that can capture temporal correlations.This model can generate streamflow by selecting different historical streamflow variables as the conditions for different months and by exploiting the conditional quantile functions of streamflows in different months with mixed D-vine copulas.The up-to-down sequential method,which couples the maximum weight approach with the Akaike information criteria and the maximum likelihood approach,was used to determine the structures of multivariate Dvine copulas.The developed model was used in a case study to synthesize the monthly streamflow at the Tangnaihai hydrological station,the inflow control station of the Longyangxia Reservoir in the Yellow River Basin.The results showed that the developed model outperformed the commonly used bivariate copula model in terms of the performance in simulating the seasonality and interannual variability of streamflow.This model provides useful information for water-related natural hazard risk assessment and integrated water resources management and utilization.展开更多
Slag carry-over during the draining of molten steel from a teeming ladle is numerically studied here. Two-phase isothermal transient 3D Computational Fluid Dynamics simulations were employed to simulate the draining p...Slag carry-over during the draining of molten steel from a teeming ladle is numerically studied here. Two-phase isothermal transient 3D Computational Fluid Dynamics simulations were employed to simulate the draining process. Two nozzle diameters, two nozzle positions and three slag heights were considered. From mass balances, the slag carry-over in terms of mass flow rate was obtained for each of the above variables. Besides, the draining times of the teeming ladle were estimated from theoretical considerations and CDF simulations, and compared.展开更多
There is a continuous and relatively stable rainy period every spring in southern China(SC).This spring precipitation process is a unique weather and climate phenomenon in East Asia.Previously,the variation characteri...There is a continuous and relatively stable rainy period every spring in southern China(SC).This spring precipitation process is a unique weather and climate phenomenon in East Asia.Previously,the variation characteristics and associated mechanisms of this precipitation process have been mostly discussed from the perspective of seasonal mean.Based on the observed and reanalysis datasets from 1982 to 2021,this study investigates the diversity of the interannual variations of monthly precipitation in spring in SC,and focuses on the potential influence of the tropical sea surface temperature(SST)anomalies.The results show that the interannual variations of monthly precipitation in spring in SC have significant differences,and the correlations between each two months are very weak.All the interannual variations of precipitation in three months are related to a similar western North Pacific anomalous anticyclone(WNPAC),and the southwesterlies at the western flank of WNPAC bring abundant water vapor for the precipitation in SC.However,the WNPAC is influenced by tropical SST anomalies in different regions each month.The interannual variation of precipitation in March in SC is mainly influenced by the signal of El Nino-Southern Oscillation,and the associated SST anomalies in the equatorial central-eastern Pacific regulate the WNPAC through the Pacific-East Asia(PEA)teleconnection.In contrast,the WNPAC associated with the interannual variation of precipitation in April can be affected by the SST anomalies in the northwestern equatorial Pacific through a thermally induced Rossby wave response.The interannual variation of precipitation in May is regulated by the SST anomalies around the western Maritime Continent,which stimulates the development of low-level anomalous anticyclones over the South China Sea and east of the Philippine Sea by driving anomalous meridional vertical circulation.展开更多
At present, carry-over research in mycotoxins experiences a change in focus. We reviewed the state-of-art knowledge regarding carry-over in aflatoxins, ochratoxin A, Fusarium toxins, patulin, ergot and citrinin. The c...At present, carry-over research in mycotoxins experiences a change in focus. We reviewed the state-of-art knowledge regarding carry-over in aflatoxins, ochratoxin A, Fusarium toxins, patulin, ergot and citrinin. The common cooccurrence of mycotoxins demands for employment of multi-toxin analysis and poses a new challenge in reliable health hazard assessment. Synergies in adverse mycotoxin effects call for a revision of various guidance levels in feed. We found a lack of risk assessment regarding carry-over of rare mycotoxins and metabolites usually considered negligible.展开更多
In this paper,we describe and analyze two datasets entitled“Homogenised monthly and daily temperature and precipitation time series in China during 1960–2021”and“Homogenised monthly and daily temperature and preci...In this paper,we describe and analyze two datasets entitled“Homogenised monthly and daily temperature and precipitation time series in China during 1960–2021”and“Homogenised monthly and daily temperature and precipitation time series in Greece during 1960–2010”.These datasets provide the homogenised monthly and daily mean(TG),minimum(TN),and maximum(TX)temperature and precipitation(RR)records since 1960 at 366 stations in China and 56stations in Greece.The datasets are available at the Science Data Bank repository and can be downloaded from https://doi.org/10.57760/sciencedb.01731 and https://doi.org/10.57760/sciencedb.01720.For China,the regional mean annual TG,TX,TN,and RR series during 1960–2021 showed significant warming or increasing trends of 0.27℃(10 yr)^(-1),0.22℃(10 yr)^(-1),0.35℃(10 yr)^(-1),and 6.81 mm(10 yr)-1,respectively.Most of the seasonal series revealed trends significant at the 0.05level,except for the spring,summer,and autumn RR series.For Greece,there were increasing trends of 0.09℃(10 yr)-1,0.08℃(10 yr)^(-1),and 0.11℃(10 yr)^(-1)for the annual TG,TX,and TN series,respectively,while a decreasing trend of–23.35 mm(10 yr)^(-1)was present for RR.The seasonal trends showed a significant warming rate for summer,but no significant changes were noted for spring(except for TN),autumn,and winter.For RR,only the winter time series displayed a statistically significant and robust trend[–15.82 mm(10 yr)^(-1)].The final homogenised temperature and precipitation time series for both China and Greece provide a better representation of the large-scale pattern of climate change over the past decades and provide a quality information source for climatological analyses.展开更多
Context: The evaluation of plasma Viral Load constitutes an indicator of the progression of the infection, the effectiveness and the tolerance of the treatment. Objective: The objective of this study is to present the...Context: The evaluation of plasma Viral Load constitutes an indicator of the progression of the infection, the effectiveness and the tolerance of the treatment. Objective: The objective of this study is to present the virological profile of Patients Living with HIV (PLHIV) after 12 months of AntiRetro Viral Treatment (ART) based on Dolutegravir (DTG) in Kinshasa. Method: The present study is a cross-sectional view of the virological profile of the twelfth month of a prospective cohort of PLHIV at M12 of DTG-based ART in Kinshasa. During the M12 appointment, a blood sample was taken for Molecular Biology analyses from all PLHIV included. Result: During the M12 appointment, 28 patients were registered, including 16 (57.1%) women. Nine (9) patients (45.0%) had an undetectable Viral Load (VL). The median VL value was 3.18 log<sub>10</sub> RNA copies/mL (1530 RNA copies/mL). The mutations K65R, T69P/N, K70R and M184V have been listed as mutations conferring resistance to Nucleotide Reverse Transcriptase Inhibitors. No mutations associated with Dolutegravir were observed at M12. Conclusion: After 12 months of AntiRetroViral Treatment based on Dolutegravir, half of the Patients on first-line ART are in a state of virological failure.展开更多
Background: In accordance with its measles elimination strategic plan 2012-2020, the Democratic Republic of the Congo (DRC) organized a follow-up vaccination campaign against measles from October to December 2019 in 2...Background: In accordance with its measles elimination strategic plan 2012-2020, the Democratic Republic of the Congo (DRC) organized a follow-up vaccination campaign against measles from October to December 2019 in 26 provinces. This study aims to establish the contribution of this supplementary vaccination campaign to protecting children against measles. Methods: The survey was carried out in November 2020 among households of the DRC, according to the 2018 revised version of the World Health Organization’s stratified cluster sampling method, using multiple stage sampling. It targeted 280 children aged 6 - 59 months per stratum or province, with 10 children in each of the 28 selected clusters. Data collection using tablets with centralized and real-time data processing was preceded by enumeration to refine the household sampling frame. Clusters and households were selected by random draw. Data collected with CS Pro 7 software were analyzed with SPSS, Epi info 7 and Excel software to determine indicators and make before-after comparisons using the McNemar test, at a precision threshold of 5%. Results: Of the 8535 surveyed children, 89.5% were vaccinatedduring the follow-up campaign and 81.6% were vaccinated before. Only 3.7% had correctly completed campaign vaccination cards. Estimated vaccination coverage increased from 80.8% before the campaign to 92.6% after the campaign (p 0.001). Vaccination coverage after campaign against measles improved in all provinces (p < 0.001) except Bas-Uele and Maniema. Thirteen provinces reached the national coverage target of 95%, compared to five before the campaign. The proportion of zero-dose children dropped significantly after this campaign from 19.2% to 7.4% (p 0.001), and even fell below 1% in six provinces. Conclusion: This measles vaccination campaign improved overall vaccination coverage by 10% and reached more unvaccinated children. Efforts must continue to improve the retention of vaccination card, the adherence of unvaccinated children and the effectiveness of routine vaccination.展开更多
The identification method revealed asymmetric wavelets of dynamics, as fractal quanta of the behavior of the surface air layer at a height of 2 m, according to the average monthly temperature at four weather stations ...The identification method revealed asymmetric wavelets of dynamics, as fractal quanta of the behavior of the surface air layer at a height of 2 m, according to the average monthly temperature at four weather stations in India (Srinagar, Jolhpur, New Delhi and Guvahati). For Srinagar station, the maximum for all years is observed in July, for Jolhpur and New Delhi stations it shifts to June, and for Guvahati it shifts to August. With a high correlation coefficient of 0.9659, 0.8640 and 0.8687, a three-factor model of the form was obtained. The altitude, longitude and latitude of the station are given sequentially. The hottest month for Srinagar over a period of 130 years is in July. At the same time, the temperature increased from 23.4 °C to 24.2 °C (by 3.31%). A noticeable decrease in the intensity of heat flows in June occurred at Jolhpur (over 125 years, a decrease from 36.2 °C to 33.3 °C, or by 8.71%) and New Delhi (over 90 years, a decrease from 35.1 °C to 32.4 °C, or by 7.69%). For almost 120 years, Guvahati has experienced complex climate changes: In 1902, the hottest month was July, but in 2021 it has shifted to August. The increase in temperature at various stations is considered. At Srinagar station in 2021, compared to 1892, temperatures increased in June, September and October. Guvahati has a 120-year increase in December, January, March and April. Temperatures have risen in February, March and April at Jolhpur in 125 years, but have risen in February and March at New Delhi Station in 90 years. Despite the presence of tropical evergreen forests, the area around Guvahati Station is expected to experience strong warming.展开更多
基金National Key Research and Development Program of China(2022YFB3903302 and 2021YFC1809104)。
文摘Rapid and accurate acquisition of soil organic matter(SOM)information in cultivated land is important for sustainable agricultural development and carbon balance management.This study proposed a novel approach to predict SOM with high accuracy using multiyear synthetic remote sensing variables on a monthly scale.We obtained 12 monthly synthetic Sentinel-2 images covering the study area from 2016 to 2021 through the Google Earth Engine(GEE)platform,and reflectance bands and vegetation indices were extracted from these composite images.Then the random forest(RF),support vector machine(SVM)and gradient boosting regression tree(GBRT)models were tested to investigate the difference in SOM prediction accuracy under different combinations of monthly synthetic variables.Results showed that firstly,all monthly synthetic spectral bands of Sentinel-2 showed a significant correlation with SOM(P<0.05)for the months of January,March,April,October,and November.Secondly,in terms of single-monthly composite variables,the prediction accuracy was relatively poor,with the highest R^(2)value of 0.36 being observed in January.When monthly synthetic environmental variables were grouped in accordance with the four quarters of the year,the first quarter and the fourth quarter showed good performance,and any combination of three quarters was similar in estimation accuracy.The overall best performance was observed when all monthly synthetic variables were incorporated into the models.Thirdly,among the three models compared,the RF model was consistently more accurate than the SVM and GBRT models,achieving an R^(2)value of 0.56.Except for band 12 in December,the importance of the remaining bands did not exhibit significant differences.This research offers a new attempt to map SOM with high accuracy and fine spatial resolution based on monthly synthetic Sentinel-2 images.
文摘Introduction: the problem of Severe Acute Malnutrition (SAM) and its consequences concern and challenge all social actors worldwide. The objective of the study was to identify the real obstacles that actors face in the integrated management of children aged 6 - 59 months suffering from SAM at the University Hospital of Mother and Child (CHUME) and the Chad-China Friendship Hospital (HATC) of N’Djamena. Methodology: this is a cross-sectional descriptive and interpretative study conducted from January to October 2023 at the CHUME and HATC of N’Djamena. It is based on questionnaires and direct observation of two hundred and thirty-six (236) parents or guardians of malnourished children admitted to these health facilities. All 236 agreed to participate freely in this study. Results: it appears from this study that the obstacles to the integrated management of malnourished children were: poor care-care relationship (26.7%) permanent product breaks (22.9%), the direct costs of services ranged from 30,000 to 60,000 FCFA (41.53%), drugs used for the treatment of patients came from the street (66.10%), malaria and anemia occupy an important place (27.5%), 57.2% respondents had monthly income below 60,000 CFAF. Conclusion: the present study carried out has identified the real bottlenecks to the integrated management of children suffering from SAM in the therapeutic nutritional units of the city of N’Djamena. .
文摘Introduction: Infant and child mortality is a worldwide concern, but developing countries such as Mali are more affected. The aim of this study was to investigate morbidity and factors associated with mortality in children aged 1 month to 15 years. Methodology: This was a cross-sectional study which took place from January 1 to December 31, 2020 covering children aged 1 month to 15 years hospitalized at the Kalaban-Coro CSRéf. Data were entered into Excel and analyzed using SPSS version 20 software. Results: Five hundred children aged 1 months to 15 years were included. The age range 1 to 5 years (53.6%) and male sex (58.2%) were the most represented. Malaria (72.2%), acute respiratory infections (6.2%) and diarrhea/dehydration (3%) were the main morbidities. Mortality was estimated at 10.6%, and the two main causes of death were malaria (56.6%) and acute respiratory infections (7.54%). Univariate analysis revealed a statistically significant association between the dependent variable (death) and age (p Conclusion: This study confirms the high rate of infant and child morbidity and mortality in our health facilities. Strengthening human resources and intensifying behavior-change communication can help reverse the trend.
基金supported by the National Natural Science Foundation of China(Grant No.52109010)the Postdoctoral Science Foundation of China(Grant No.2021M701047)the China National Postdoctoral Program for Innovative Talents(Grant No.BX20200113).
文摘Copula functions have been widely used in stochastic simulation and prediction of streamflow.However,existing models are usually limited to single two-dimensional or three-dimensional copulas with the same bivariate block for all months.To address this limitation,this study developed a mixed D-vine copula-based conditional quantile model that can capture temporal correlations.This model can generate streamflow by selecting different historical streamflow variables as the conditions for different months and by exploiting the conditional quantile functions of streamflows in different months with mixed D-vine copulas.The up-to-down sequential method,which couples the maximum weight approach with the Akaike information criteria and the maximum likelihood approach,was used to determine the structures of multivariate Dvine copulas.The developed model was used in a case study to synthesize the monthly streamflow at the Tangnaihai hydrological station,the inflow control station of the Longyangxia Reservoir in the Yellow River Basin.The results showed that the developed model outperformed the commonly used bivariate copula model in terms of the performance in simulating the seasonality and interannual variability of streamflow.This model provides useful information for water-related natural hazard risk assessment and integrated water resources management and utilization.
文摘Slag carry-over during the draining of molten steel from a teeming ladle is numerically studied here. Two-phase isothermal transient 3D Computational Fluid Dynamics simulations were employed to simulate the draining process. Two nozzle diameters, two nozzle positions and three slag heights were considered. From mass balances, the slag carry-over in terms of mass flow rate was obtained for each of the above variables. Besides, the draining times of the teeming ladle were estimated from theoretical considerations and CDF simulations, and compared.
基金National Key Research and Development Program of China(2019YFC1510400)National Natural Science Foundation of China(41975080)+1 种基金Guangdong Major Project of Basic and Applied Basic Research(2020B0301030004)Guangdong Province Key Laboratory for Climate Change and Natural Disaster Studies(2020B1212060025)。
文摘There is a continuous and relatively stable rainy period every spring in southern China(SC).This spring precipitation process is a unique weather and climate phenomenon in East Asia.Previously,the variation characteristics and associated mechanisms of this precipitation process have been mostly discussed from the perspective of seasonal mean.Based on the observed and reanalysis datasets from 1982 to 2021,this study investigates the diversity of the interannual variations of monthly precipitation in spring in SC,and focuses on the potential influence of the tropical sea surface temperature(SST)anomalies.The results show that the interannual variations of monthly precipitation in spring in SC have significant differences,and the correlations between each two months are very weak.All the interannual variations of precipitation in three months are related to a similar western North Pacific anomalous anticyclone(WNPAC),and the southwesterlies at the western flank of WNPAC bring abundant water vapor for the precipitation in SC.However,the WNPAC is influenced by tropical SST anomalies in different regions each month.The interannual variation of precipitation in March in SC is mainly influenced by the signal of El Nino-Southern Oscillation,and the associated SST anomalies in the equatorial central-eastern Pacific regulate the WNPAC through the Pacific-East Asia(PEA)teleconnection.In contrast,the WNPAC associated with the interannual variation of precipitation in April can be affected by the SST anomalies in the northwestern equatorial Pacific through a thermally induced Rossby wave response.The interannual variation of precipitation in May is regulated by the SST anomalies around the western Maritime Continent,which stimulates the development of low-level anomalous anticyclones over the South China Sea and east of the Philippine Sea by driving anomalous meridional vertical circulation.
文摘At present, carry-over research in mycotoxins experiences a change in focus. We reviewed the state-of-art knowledge regarding carry-over in aflatoxins, ochratoxin A, Fusarium toxins, patulin, ergot and citrinin. The common cooccurrence of mycotoxins demands for employment of multi-toxin analysis and poses a new challenge in reliable health hazard assessment. Synergies in adverse mycotoxin effects call for a revision of various guidance levels in feed. We found a lack of risk assessment regarding carry-over of rare mycotoxins and metabolites usually considered negligible.
基金funded by the Hellenic and Chinese Governments,in the frame of the Greek-Chinese R&T Cooperation Programme project“Comparative study of extreme climate indices in China and Europe/Greece,based on homogenised daily observations—CLIMEX”(Contract T7ΔKI-00046)the National Key Technologies Research and Development Program“Comparative study of changing climate extremes between China and Europe/Greece based on homogenised daily observations”(Grant No.2017YFE0133600)。
文摘In this paper,we describe and analyze two datasets entitled“Homogenised monthly and daily temperature and precipitation time series in China during 1960–2021”and“Homogenised monthly and daily temperature and precipitation time series in Greece during 1960–2010”.These datasets provide the homogenised monthly and daily mean(TG),minimum(TN),and maximum(TX)temperature and precipitation(RR)records since 1960 at 366 stations in China and 56stations in Greece.The datasets are available at the Science Data Bank repository and can be downloaded from https://doi.org/10.57760/sciencedb.01731 and https://doi.org/10.57760/sciencedb.01720.For China,the regional mean annual TG,TX,TN,and RR series during 1960–2021 showed significant warming or increasing trends of 0.27℃(10 yr)^(-1),0.22℃(10 yr)^(-1),0.35℃(10 yr)^(-1),and 6.81 mm(10 yr)-1,respectively.Most of the seasonal series revealed trends significant at the 0.05level,except for the spring,summer,and autumn RR series.For Greece,there were increasing trends of 0.09℃(10 yr)-1,0.08℃(10 yr)^(-1),and 0.11℃(10 yr)^(-1)for the annual TG,TX,and TN series,respectively,while a decreasing trend of–23.35 mm(10 yr)^(-1)was present for RR.The seasonal trends showed a significant warming rate for summer,but no significant changes were noted for spring(except for TN),autumn,and winter.For RR,only the winter time series displayed a statistically significant and robust trend[–15.82 mm(10 yr)^(-1)].The final homogenised temperature and precipitation time series for both China and Greece provide a better representation of the large-scale pattern of climate change over the past decades and provide a quality information source for climatological analyses.
文摘Context: The evaluation of plasma Viral Load constitutes an indicator of the progression of the infection, the effectiveness and the tolerance of the treatment. Objective: The objective of this study is to present the virological profile of Patients Living with HIV (PLHIV) after 12 months of AntiRetro Viral Treatment (ART) based on Dolutegravir (DTG) in Kinshasa. Method: The present study is a cross-sectional view of the virological profile of the twelfth month of a prospective cohort of PLHIV at M12 of DTG-based ART in Kinshasa. During the M12 appointment, a blood sample was taken for Molecular Biology analyses from all PLHIV included. Result: During the M12 appointment, 28 patients were registered, including 16 (57.1%) women. Nine (9) patients (45.0%) had an undetectable Viral Load (VL). The median VL value was 3.18 log<sub>10</sub> RNA copies/mL (1530 RNA copies/mL). The mutations K65R, T69P/N, K70R and M184V have been listed as mutations conferring resistance to Nucleotide Reverse Transcriptase Inhibitors. No mutations associated with Dolutegravir were observed at M12. Conclusion: After 12 months of AntiRetroViral Treatment based on Dolutegravir, half of the Patients on first-line ART are in a state of virological failure.
文摘Background: In accordance with its measles elimination strategic plan 2012-2020, the Democratic Republic of the Congo (DRC) organized a follow-up vaccination campaign against measles from October to December 2019 in 26 provinces. This study aims to establish the contribution of this supplementary vaccination campaign to protecting children against measles. Methods: The survey was carried out in November 2020 among households of the DRC, according to the 2018 revised version of the World Health Organization’s stratified cluster sampling method, using multiple stage sampling. It targeted 280 children aged 6 - 59 months per stratum or province, with 10 children in each of the 28 selected clusters. Data collection using tablets with centralized and real-time data processing was preceded by enumeration to refine the household sampling frame. Clusters and households were selected by random draw. Data collected with CS Pro 7 software were analyzed with SPSS, Epi info 7 and Excel software to determine indicators and make before-after comparisons using the McNemar test, at a precision threshold of 5%. Results: Of the 8535 surveyed children, 89.5% were vaccinatedduring the follow-up campaign and 81.6% were vaccinated before. Only 3.7% had correctly completed campaign vaccination cards. Estimated vaccination coverage increased from 80.8% before the campaign to 92.6% after the campaign (p 0.001). Vaccination coverage after campaign against measles improved in all provinces (p < 0.001) except Bas-Uele and Maniema. Thirteen provinces reached the national coverage target of 95%, compared to five before the campaign. The proportion of zero-dose children dropped significantly after this campaign from 19.2% to 7.4% (p 0.001), and even fell below 1% in six provinces. Conclusion: This measles vaccination campaign improved overall vaccination coverage by 10% and reached more unvaccinated children. Efforts must continue to improve the retention of vaccination card, the adherence of unvaccinated children and the effectiveness of routine vaccination.
文摘The identification method revealed asymmetric wavelets of dynamics, as fractal quanta of the behavior of the surface air layer at a height of 2 m, according to the average monthly temperature at four weather stations in India (Srinagar, Jolhpur, New Delhi and Guvahati). For Srinagar station, the maximum for all years is observed in July, for Jolhpur and New Delhi stations it shifts to June, and for Guvahati it shifts to August. With a high correlation coefficient of 0.9659, 0.8640 and 0.8687, a three-factor model of the form was obtained. The altitude, longitude and latitude of the station are given sequentially. The hottest month for Srinagar over a period of 130 years is in July. At the same time, the temperature increased from 23.4 °C to 24.2 °C (by 3.31%). A noticeable decrease in the intensity of heat flows in June occurred at Jolhpur (over 125 years, a decrease from 36.2 °C to 33.3 °C, or by 8.71%) and New Delhi (over 90 years, a decrease from 35.1 °C to 32.4 °C, or by 7.69%). For almost 120 years, Guvahati has experienced complex climate changes: In 1902, the hottest month was July, but in 2021 it has shifted to August. The increase in temperature at various stations is considered. At Srinagar station in 2021, compared to 1892, temperatures increased in June, September and October. Guvahati has a 120-year increase in December, January, March and April. Temperatures have risen in February, March and April at Jolhpur in 125 years, but have risen in February and March at New Delhi Station in 90 years. Despite the presence of tropical evergreen forests, the area around Guvahati Station is expected to experience strong warming.