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Effect of Partial Replacement of Fly Ash by Decoration Waste Powder on the Fresh and Mechanical Properties of Geopolymer Masonry Mortar
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作者 刘惠 ZHANG Ruidong +2 位作者 朱平华 WANG Xinjie CHEN Chunhong 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS CSCD 2024年第3期698-704,共7页
This study aims to investigate the feasibility of using decoration waste powder(DWP)as a partial replacement for fly ash(FA)in the preparation of geopolymer masonry mortar,and to examine the effect of different DWP re... This study aims to investigate the feasibility of using decoration waste powder(DWP)as a partial replacement for fly ash(FA)in the preparation of geopolymer masonry mortar,and to examine the effect of different DWP replacement rates(0%-40%)on the fresh and mechanical properties of the mortar.The results showed that each group of geopolymer masonry mortar exhibited excellent water retention performance,with a water retention rate of 100%,which was due to the unique geopolymer mortar system and high viscosity of the alkaline activator solution.Compared to the control group,the flowability of the mortar containing lower contents of DWP(10%and 20%)was higher.However,as the DWP replacement rate further increased,the flowability gradually decreased.The DWP could absorb the free water in the reaction system of geopolymer mortar,thereby limiting the occurrence of geopolymerization reaction.The incorporation of DWP in the mortar resulted in a decrease in compressive strength compared to the mortar without DWP.However,even at a replacement rate of 40%,the compressive strength of the mortar still exceeded 15 MPa,which met the requirements of the masonry mortar.It was feasible to use DWP in the geopolymer masonry mortar.Although the addition of DWP caused some performance loss,it did not affect its usability. 展开更多
关键词 fly ash-based geopolymer decoration waste powder masonry mortar WORKABILITY compressive strength
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基于改进Ratio统计量的重尾AR(p)时间序列均值变点检验
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作者 张思 刘叶 金浩 《统计与决策》 北大核心 2024年第2期52-57,共6页
文章提出两个改进的Ratio统计量来研究重尾AR(p)时间序列均值变点检验问题,在原假设下推导了统计量的渐近分布,且在备择假设下证明了其一致性。由于重尾指数未知且难以估计,因此结合Wild Bootstrap重抽样方法来确定渐近分布的临界值;在... 文章提出两个改进的Ratio统计量来研究重尾AR(p)时间序列均值变点检验问题,在原假设下推导了统计量的渐近分布,且在备择假设下证明了其一致性。由于重尾指数未知且难以估计,因此结合Wild Bootstrap重抽样方法来确定渐近分布的临界值;在均值变点存在的情形下,给出了变点位置的一致估计量。数值模拟结果表明:统计量的临界值均不受重尾指数和自回归系数的影响,其经验水平和经验势均取得满意的效果;尤其在原假设下,积分型Ratio统计量的经验水平表现出更好的稳健性,而在备择假设下,最值型Ratio统计量则具备更好的显著性。最后,基于一组股票数据,从实际应用角度进一步阐明所提方法的有效性和可行性。 展开更多
关键词 重尾序列 ratio统计量 均值变点 Wild Bootstrap
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Effects of Filler-Asphalt Ratio on the Properties of Lignin and Polyester Fiber Reinforced SMPU/SBS Modified Asphalt Mortar
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作者 Wenjing Xia Jinhui Wang +1 位作者 Tao Xu Nan Jiang 《Journal of Renewable Materials》 EI 2023年第8期3387-3402,共16页
To understand the effects offiller-asphalt ratio on different properties of lignin and polyesterfiber reinforced shape memory polyurethane(SMPU)/styrene butadiene styrene(SBS)composite modified asphalt mortar(PSAM),as we... To understand the effects offiller-asphalt ratio on different properties of lignin and polyesterfiber reinforced shape memory polyurethane(SMPU)/styrene butadiene styrene(SBS)composite modified asphalt mortar(PSAM),as well as to reveal the reinforcing and toughening mechanisms of lignin and polyesterfibers on PSAM,SMPU,SBS and mineral powder werefirst utilized to prepare PSAM.Then the conventional,rheological and anti-cracking properties of ligninfiber reinforced PSAM(LFAM)and polyesterfiber reinforced PSAM(PFAM)at dif-ferentfiller-asphalt ratios were characterized.Test results indicate that the shear strength,deformation resistance and viscosity are increased after adding 0.8wt%ligninfiber or polyesterfiber and increasing thefiller-asphalt ratio from 0.8 to 1.2.The optimalfiller-asphalt ratio of 1.0 is proposed after comprehensive performance assessments of PSAM.Polyesterfiber shows a better reinforcing effect than ligninfiber,but its improvement in the thermal stability of PSAM is not significant at high temperatures.Additionally,the complex modulus,storage modulus,loss modulus and rutting resistance factor of PSAM are improved after adding ligninfiber and polyesterfiber,as well as show an increasing trend as thefiller-asphalt ratio is raised,but the phase angle is gradually decreased.Further,the increase of elastic components in PSAM effectively enhances the anti-deformation ability of PSAM at high temperatures,and polyesterfiber more obviously improves the high-temperature deformation resistance of PSAM than ligninfiber.Finally,the anti-cracking performance of PFAM and LFAM at low temperatures is reduced by 74.2%and 46.7%,respectively,as thefiller-asphalt ratio is raised from 0.8 to 1.2.The low-temperature anti-cracking performance of LFAM is lower than that of PFAM at the samefiller-asphalt ratio,even lower than that of PSA.Compared with ligninfiber,the anti-cracking performance and deformation resistance of PSAM at low temperature is more greatly enhanced by polyester fiber. 展开更多
关键词 Asphalt mortar fiber reinforcement filler-asphalt ratio anti-cracking performance high-temperature stability deformation resistance
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Influence of Bayer Red Mud on the Operational and Mechanical Characteristics of Composite Cement Mortar
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作者 Cheng Hu Weiheng Xiang +6 位作者 Ping Chen Yi Yang Libo Zhou Jiufang Jiang Shunkai Li Yang Ming Qing Li 《Journal of Renewable Materials》 EI 2023年第11期3945-3956,共12页
The aim of this study is to enhance the value and utilization of red mud generated in the Bayer process by preparing composite cement mortars.The effects of two different types of Bayer red mud with varying physical a... The aim of this study is to enhance the value and utilization of red mud generated in the Bayer process by preparing composite cement mortars.The effects of two different types of Bayer red mud with varying physical and chemical characteristics on the fluidity,mechanical strength,mineral composition,and microstructure of the composite cement mortar were systematically evaluated.The results showed that the optimal addition of red mud A was 10 wt%,while it was 20 wt% for red mud B.The mechanical properties of the composite cement mortar met the standards for P·O42.5 cement.Furthermore,the composite mortar with the addition of red mud B showed higher flexural and compressive strengths compared to the composite mortar with red mud A.This improvement is attributed to the smaller particle size of red mud B,which filled the micro-pores and increased the compactness of the cement stone,as well as its higher content of Na_(2)O,K_(2)O,and other free alkalis,which resulted in more obvious alkali activation,accelerating the hydration of the active minerals in the slurry. 展开更多
关键词 Bayer red mud composite cement mortar FLUIDITY mechanical strength MICROSTRUCTURE
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Yields,growth and water use under chemical topping in relations to row configuration and plant density in drip-irrigated cotton 被引量:1
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作者 Wang Xuejiao Hu Yanping +10 位作者 Ji Chunrong Chen Yongfan Sun Shuai Zhang Zeshan Zhang Yutong Wang Sen Yang Mingfeng Ji Fen Guo Yanyun Li Jie Zhang Lizhen 《Journal of Cotton Research》 CAS 2024年第2期123-136,共14页
Background Water deficit is an important problem in agricultural production in arid regions.With the advent of wholly mechanized technology for cotton planting in Xinjiang,it is important to determine which planting m... Background Water deficit is an important problem in agricultural production in arid regions.With the advent of wholly mechanized technology for cotton planting in Xinjiang,it is important to determine which planting mode could achieve high yield,fiber quality and water use efficiency(WUE).This study aimed to explore if chemical topping affected cotton yield,quality and water use in relation to row configuration and plant densities.Results Experiments were carried out in Xinjiang China,in 2020 and 2021 with two topping method,manual topping and chemical topping,two plant densities,low and high,and two row configurations,i.e.,76 cm equal rows and 10+66 cm narrow-wide rows,which were commonly applied in matching harvest machine.Chemical topping increased seed cotton yield,but did not affect cotton fiber quality comparing to traditional manual topping.Under equal row spacing,the WUE in higher density was 62.4%higher than in the lower one.However,under narrow-wide row spacing,the WUE in lower density was 53.3%higher than in higher one(farmers’practice).For machine-harvest cotton in Xinjiang,the optimal row configuration and plant density for chemical topping was narrow-wide rows with 15 plants m-2 or equal rows with 18 plants m-2.Conclusion The plant density recommended in narrow-wide rows was less than farmers’practice and the density in equal rows was moderate with local practice.Our results provide new knowledge on optimizing agronomic managements of machine-harvested cotton for both high yield and water efficient. 展开更多
关键词 Yield components Fiber quality TRANSPIratioN Water use efficiency Heat ratio method(HRM)
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A gated recurrent unit model to predict Poisson’s ratio using deep learning 被引量:1
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作者 Fahd Saeed Alakbari Mysara Eissa Mohyaldinn +4 位作者 Mohammed Abdalla Ayoub Ibnelwaleed A.Hussein Ali Samer Muhsan Syahrir Ridha Abdullah Abduljabbar Salih 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第1期123-135,共13页
Static Poisson’s ratio(vs)is crucial for determining geomechanical properties in petroleum applications,namely sand production.Some models have been used to predict vs;however,the published models were limited to spe... Static Poisson’s ratio(vs)is crucial for determining geomechanical properties in petroleum applications,namely sand production.Some models have been used to predict vs;however,the published models were limited to specific data ranges with an average absolute percentage relative error(AAPRE)of more than 10%.The published gated recurrent unit(GRU)models do not consider trend analysis to show physical behaviors.In this study,we aim to develop a GRU model using trend analysis and three inputs for predicting n s based on a broad range of data,n s(value of 0.1627-0.4492),bulk formation density(RHOB)(0.315-2.994 g/mL),compressional time(DTc)(44.43-186.9 μs/ft),and shear time(DTs)(72.9-341.2μ s/ft).The GRU model was evaluated using different approaches,including statistical error an-alyses.The GRU model showed the proper trends,and the model data ranges were wider than previous ones.The GRU model has the largest correlation coefficient(R)of 0.967 and the lowest AAPRE,average percent relative error(APRE),root mean square error(RMSE),and standard deviation(SD)of 3.228%,1.054%,4.389,and 0.013,respectively,compared to other models.The GRU model has a high accuracy for the different datasets:training,validation,testing,and the whole datasets with R and AAPRE values were 0.981 and 2.601%,0.966 and 3.274%,0.967 and 3.228%,and 0.977 and 2.861%,respectively.The group error analyses of all inputs show that the GRU model has less than 5% AAPRE for all input ranges,which is superior to other models that have different AAPRE values of more than 10% at various ranges of inputs. 展开更多
关键词 Static Poisson’s ratio Deep learning Gated recurrent unit(GRU) Sand control Trend analysis Geomechanical properties
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Serum cystatin C,monocyte/high-density lipoprotein-C ratio,and uric acid for the diagnosis of coronary heart disease and heart failure 被引量:1
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作者 Ming Li Da-Hao Yuan +2 位作者 Zhi Yang Teng-Xiang Luw Xiao-Biao Zou 《World Journal of Clinical Cases》 SCIE 2024年第18期3461-3467,共7页
BACKGROUND Coronary heart disease(CHD)and heart failure(HF)are the major causes of morbidity and mortality worldwide.Early and accurate diagnoses of CHD and HF are essential for optimal management and prognosis.Howeve... BACKGROUND Coronary heart disease(CHD)and heart failure(HF)are the major causes of morbidity and mortality worldwide.Early and accurate diagnoses of CHD and HF are essential for optimal management and prognosis.However,conventional diagnostic methods such as electrocardiography,echocardiography,and cardiac biomarkers have certain limitations,such as low sensitivity,specificity,availability,and cost-effectiveness.Therefore,there is a need for simple,noninvasive,and reliable biomarkers to diagnose CHD and HF.AIM To investigate serum cystatin C(Cys-C),monocyte/high-density lipoprotein cholesterol ratio(MHR),and uric acid(UA)diagnostic values for CHD and HF.METHODS We enrolled 80 patients with suspected CHD or HF who were admitted to our hospital between July 2022 and July 2023.The patients were divided into CHD(n=20),HF(n=20),CHD+HF(n=20),and control groups(n=20).The serum levels of Cys-C,MHR,and UA were measured using immunonephelometry and an enzymatic method,respectively,and the diagnostic values for CHD and HF were evaluated using receiver operating characteristic(ROC)curve analysis.RESULTS Serum levels of Cys-C,MHR,and UA were significantly higher in the CHD,HF,and CHD+HF groups than those in the control group.The serum levels of Cys-C,MHR,and UA were significantly higher in the CHD+HF group than those in the CHD or HF group.The ROC curve analysis showed that serum Cys-C,MHR,and UA had good diagnostic performance for CHD and HF,with areas under the curve ranging from 0.78 to 0.93.The optimal cutoff values of serum Cys-C,MHR,and UA for diagnosing CHD,HF,and CHD+HF were 1.2 mg/L,0.9×10^(9),and 389μmol/L;1.4 mg/L,1.0×10^(9),and 449μmol/L;and 1.6 mg/L,1.1×10^(9),and 508μmol/L,respectively.CONCLUSION Serum Cys-C,MHR,and UA are useful biomarkers for diagnosing CHD and HF,and CHD+HF.These can provide information for decision-making and risk stratification in patients with CHD and HF. 展开更多
关键词 Serum cystatin C Monocyte/high-density lipoprotein-C ratio Uric acid Coronary heart disease Heart failure Risk stratification
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Evolution of Biofilm and Its Effect on Microstructure of Mortar Surfaces in Simulated Seawater
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作者 荣辉 YU Chenglong 张颖 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS CSCD 2024年第1期234-243,共10页
To explore the role of biofilm formation on the corrosion of marine concrete structures, we investigated the attachment of biofilm on mortar surfaces in simulated seawater and the influence of biofilm on the microstru... To explore the role of biofilm formation on the corrosion of marine concrete structures, we investigated the attachment of biofilm on mortar surfaces in simulated seawater and the influence of biofilm on the microstructure of mortar surfaces. The results show that the evolution of biofilm on mortar surfaces in simulated seawater is closely related to the corrosion suffered by the mortar, and the process of biofilm attachment and shedding is continuous and cyclical. It is found that the specimens in the absence of biofilm attachment are more severely eroded internally by the corrosive medium in simulated seawater than those in the presence of biofilm attachment. For the specimens without biofilm attachment, after 60 days, gypsum forms,and after 120 days, the number of pores in the mortar is reduced. In contrast, for the specimens in the presence of biofilm attachment, gypsum could only be detected after 90 days, and fewer pores are filled. Therefore, the formation of biofilm could delay the invasion of the corrosive medium into the interior of mortar during the evolution of biofilm on mortar surfaces, mitigating the corrosion of mortars in seawater. 展开更多
关键词 biofilm attachment mortar sulfur-oxidizing bacteria GYPSUM simulated seawater MICROSTRUCTURE
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An Investigation into the Performances of Cement Mortar Incorporating Superabsorbent Polymer Synthesized with Kaolin
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作者 Xiao Huang Jin Yang 《Fluid Dynamics & Materials Processing》 EI 2024年第6期1393-1406,共14页
Cement-based materials are fundamental in the construction industry,and enhancing their properties is an ongoing challenge.The use of superabsorbent polymers(SAP)has gained significant attention as a possible way to i... Cement-based materials are fundamental in the construction industry,and enhancing their properties is an ongoing challenge.The use of superabsorbent polymers(SAP)has gained significant attention as a possible way to improve the performance of cement-based materials due to their unique water-absorption and retention properties.This study investigates the multifaceted impact of kaolin intercalation-modified superabsorbent polymers(K-SAP)on the properties of cement mortar.The results show that K-SAP significantly affects the cement mortar’s rheological behavior,with distinct phases of water absorption and release,leading to changes in workability over time.Furthermore,K-SAP alters the hydration kinetics,delaying the exothermic peak of hydration and subsequently modifying the heat release kinetics.Notably,K-SAP effectively maintains a higher internal relative humidity within the mortar,reducing the autogenous shrinkage behavior.Moreover,K-SAP can have a beneficial effect on pore structure and this can be ascribed to the internal curing effect of released water from K-SAP. 展开更多
关键词 Superabsorbent polymer KAOLIN cement mortar rheological behavior autogenous shrinkage
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Systemic immune-inflammation index,neutrophilto-lymphocyte ratio,and platelet-to-lymphocyte ratio in patients with type 2 diabetes at different stages of diabetic retinopathy
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作者 Ying Gao Rong-Xin Lu +6 位作者 Yun Tang Xin-Yi Yang Hu Meng Chang-Lin Zhao Yi-Lu Chen Feng Yan Qian Cao 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第5期877-882,共6页
AIM:To investigate systemic immune-inflammation index(SII),neutrophil-to-lymphocyte ratio(NLR),and plateletto-lymphocyte ratio(PLR)levels in patients with type 2 diabetes at different stages of diabetic retinopathy(DR... AIM:To investigate systemic immune-inflammation index(SII),neutrophil-to-lymphocyte ratio(NLR),and plateletto-lymphocyte ratio(PLR)levels in patients with type 2 diabetes at different stages of diabetic retinopathy(DR).METHODS:This retrospective study included 141 patients with type 2 diabetes mellitus(DM):45 without diabetic retinopathy(NDR),47 with non-proliferative diabetic retinopathy(NPDR),and 49 with proliferative diabetic retinopathy(PDR).Complete blood counts were obtained,and NLR,PLR,and SII were calculated.The study analysed the ability of inflammatory markers to predict DR using receiver operating characteristic(ROC)curves.The relationships between DR stages and SII,PLR,and NLP were assessed using multivariate logistic regression.RESULTS:The average NLR,PLR,and SII were higher in the PDR group than in the NPDR group(P=0.011,0.043,0.009,respectively);higher in the NPDR group than in the NDR group(P<0.001 for all);and higher in the PDR group than in the NDR group(P<0.001 for all).In the ROC curve analysis,the NLR,PLR,and SII were significant predictors of DR(P<0.001 for all).The highest area under the curve(AUC)was for the PLR(0.929 for PLR,0.925 for SII,and 0.821 for NLR).Multivariate regression analysis indicated that NLR,PLR,and SII were statistically significantly positive and independent predictors for the DR stages in patients with DM[odds ratio(OR)=1.122,95%confidence interval(CI):0.200–2.043,P<0.05;OR=0.038,95%CI:0.018–0.058,P<0.05;OR=0.007,95%CI:0.001–0.01,P<0.05,respectively).CONCLUSION:The NLR,PLR,and SII may be used as predictors of DR. 展开更多
关键词 diabetic retinopathy neutrophil-tolymphocyte ratio platelet-to-lymphocyte ratio systemic immune-inflammation index
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Predictive Ability of Hypertriglyceridemic Waist,Hypertriglyceridemic Waist-to-Height Ratio,and Waist-to-Hip Ratio for Cardiometabolic Risk Factors Clustering Screening among Chinese Children and Adolescents
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作者 XIAO Tian Li YUAN Shu Qian +6 位作者 GAO Jing Yu Julien SBaker YANG Yi De WANG Xi Jie ZHENG Chan Juan DONG Yan Hui ZOU Zhi Yong 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2024年第3期233-241,共9页
Objective Hypertriglyceridemic waist(HW),hypertriglyceridemic waist-to-height ratio(HWHtR),and waist-to-hip ratio(WHR)have been shown to be indicators of cardiometabolic risk factors.However,it is not clear which indi... Objective Hypertriglyceridemic waist(HW),hypertriglyceridemic waist-to-height ratio(HWHtR),and waist-to-hip ratio(WHR)have been shown to be indicators of cardiometabolic risk factors.However,it is not clear which indicator is more suitable for children and adolescents.We aimed to investigate the relationship between HW,HWHtR,WHR,and cardiovascular risk factors clustering to determine the best screening tools for cardiometabolic risk in children and adolescents.Methods This was a national cross-sectional study.Anthropometric and biochemical variables were assessed in approximately 70,000 participants aged 6–18 years from seven provinces in China.Demographics,physical activity,dietary intake,and family history of chronic diseases were obtained through questionnaires.ANOVA,χ2 and logistic regression analysis was conducted.Results A significant sex difference was observed for HWHtR and WHR,but not for HW phenotype.The risk of cardiometabolic health risk factor clustering with HW phenotype or the HWHtR phenotype was significantly higher than that with the non-HW or non-HWHtR phenotypes among children and adolescents(HW:OR=12.22,95%CI:9.54-15.67;HWHtR:OR=9.70,95%CI:6.93-13.58).Compared with the HW and HWHtR phenotypes,the association between risk of cardiometabolic health risk factors(CHRF)clustering and high WHR was much weaker and not significant(WHR:OR=1.14,95%CI:0.97-1.34).Conclusion Compared with HWHtR and WHR,the HW phenotype is a more convenient indicator with higher applicability to screen children and adolescents for cardiovascular risk factors. 展开更多
关键词 Hypertriglyceridemic waist Waist-to-hip ratio Children and adolescents China Hypertriglyceridemic waist-to-height ratio Cardiovascular risk factors
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Influence of Recycled Concrete Fine Powder on Durability of Cement Mortar
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作者 Yadong Bian Xuan Qiu +2 位作者 Jihui Zhao Zhong Li Jiana Ouyang 《Fluid Dynamics & Materials Processing》 EI 2024年第1期45-58,共14页
In this paper,the durability of cement mortar prepared with a recycled-concrete fine powder(RFP)was examined;including the analysis of a variety of aspects,such as the carbonization,sulfate attack and chloride ion ero... In this paper,the durability of cement mortar prepared with a recycled-concrete fine powder(RFP)was examined;including the analysis of a variety of aspects,such as the carbonization,sulfate attack and chloride ion erosion resistance.The results indicate that the influence of RFP on these three aspects is different.The carbonization depth after 30 days and the chloride diffusion coefficient of mortar containing 10%RFP decreased by 13.3%and 28.19%.With a further increase in the RFP content,interconnected pores formed between the RFP particles,leading to an acceleration of the penetration rate of CO_(2)and Cl^(−).When the RFP content was less than 50%,the corrosion resistance coefficient of the compressive strength of the mortar was 0.84-1.05 after 90 days of sulfate attack.But the expansion and cracking of the mortar was effectively alleviated due to decrease of the gypsum production.Scanning electron microscope(SEM)analysis has confirmed that 10%RFP contributes to the formation of a dense microstructure in the cement mortar. 展开更多
关键词 Recycled concrete fine powder cement mortar CARBONIZATION SULFATE chloride ion DURABILITY
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Analysis of Calcined Red Mud Properties and Related Mortar Performances
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作者 Zhengfan Lyu Yulin Li +2 位作者 Mengmeng Fan Yan Huang Chenguang Li 《Fluid Dynamics & Materials Processing》 EI 2024年第5期901-913,共13页
Red mud(RM)is a low-activity industrial solid waste,and its utilization as a resource is currently a hot topic.In this study,the micro characteristics of red mud at different calcination temperatures were analyzed usi... Red mud(RM)is a low-activity industrial solid waste,and its utilization as a resource is currently a hot topic.In this study,the micro characteristics of red mud at different calcination temperatures were analyzed using X-ray diffraction and scanning electron microscopy.The performance of calcined red mud was determined through mortar strength tests.Results indicate that high-temperature calcination can change the mineral composition and microstructure of red mud,and increase the surface roughness and specific surface area.At the optimal temperature of 700°C,the addition of calcined red mud still leads to a decrease in mortar strength,but its activity index and flexural coefficient increase by 16.2%and 11.9%with respect to uncalcined red mud,reaching values of 0.826 and 0.974,respectively.Compared with the control group,the synergistic activation of calcined red mud with slag can increase the compressive and flexural strength of the mortar by 12.9%and 1.5%,reaching 8.7 and 62.4 MPa,respectively.Correspondingly,the activity index and flexural coefficient of the calcined RM and GGBS(Ground Granulated Blast furnace Slag)mixtures also increase to 1.015 and 1.130,respectively. 展开更多
关键词 Red mud SLAG thermal activation synergistic activation mortar test microscopic properties
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Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio:Markers predicting immune-checkpoint inhibitor efficacy and immune-related adverse events
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作者 Qiu-Yu Jiang Ru-Yi Xue 《World Journal of Gastrointestinal Oncology》 SCIE 2024年第3期577-582,共6页
We conducted a comprehensive review of existing prediction models pertaining to the efficacy of immune-checkpoint inhibitor(ICI)and the occurrence of immune-related adverse events(irAEs).The predictive potential of ne... We conducted a comprehensive review of existing prediction models pertaining to the efficacy of immune-checkpoint inhibitor(ICI)and the occurrence of immune-related adverse events(irAEs).The predictive potential of neutrophil-to-lymphocyte ratio(NLR)and platelet-to-lymphocyte ratio(PLR)in determining ICI effectiveness has been extensively investigated,while limited research has been conducted on predicting irAEs.Furthermore,the combined model incor-porating NLR and PLR,either with each other or in conjunction with additional markers such as carcinoembryonic antigen,exhibits superior predictive capabilities compared to individual markers alone.NLR and PLR are promising markers for clinical applications.Forthcoming models ought to incorporate established efficacious models and newly identified ones,thereby constituting a multifactor composite model.Furthermore,efforts should be made to explore effective clinical application approaches that enhance the predictive accuracy and efficiency. 展开更多
关键词 Neutrophil-to-lymphocyte ratio Platelet-to-lymphocyte ratio Immunecheckpoint inhibitor Immune-related adverse event
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Study on physical and mechanical properties of cement asphalt emulsified mortar under track slab
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作者 Tao Wang Shaoliang Wu +5 位作者 Hengqiong Jia Shanqing Peng Haiyan Li Piyan Shao Zhao Wei Yi Shi 《Railway Sciences》 2024年第2期227-238,共12页
Purpose–During the construction process of the China Railway Track System(CRTS)I type filling layer,the nonwoven fabric bags have been used as grouting templates for cement asphalt(CA)emulsified mortar.The porous str... Purpose–During the construction process of the China Railway Track System(CRTS)I type filling layer,the nonwoven fabric bags have been used as grouting templates for cement asphalt(CA)emulsified mortar.The porous structure of nonwoven fabrics endowed the templates with breathability and water permeability.The standard requires that the volume expansion rate of CA mortar must be controlled within 1%–3%,which can generate expansion pressure to ensure that the cavities under track slabs are filled fully.However,the expansion pressure caused some of the water to seep out from the periphery of the filling bag,and it would affect the actual mix proportion of CA mortar.The differences in physical and mechanical properties between the CA mortar under track slabs and the CA mortar formed in the laboratory were studied in this paper.The relevant results could provide important methods for the research of filling layer materials for CRTS I type and other types of ballastless tracks in China.Design/methodology/approach–During the inspection of filling layer,the samples of CA mortar from different working conditions and raw materials were taken by uncovering the track slabs and drilling cores.The physical and mechanical properties of CA mortar under the filling layer of the slab were systematically analyzed by testing the electrical flux,compressive strength and density of mortar in different parts of the filling layer.Findings–In this paper,the electric flux,the physical properties and mechanical properties of different parts of CA mortar under the track slab were investigated.The results showed that the density,electric flux and compressive strength of CA mortar were affected by the composition of raw materials for dry powders and different parts of the filling layer.In addition,the electrical flux of CA mortar gradually decreased within 90 days’age.The electrical flux of samples with the thickness of 54 mm was lower than 500 C.Therefore,the impermeability and durability of CA mortar could be improved by increasing the thickness of filling layer.Besides,the results showed that the compressive strength of CA mortar increased,while the density and electric flux decreased gradually,with the prolongation of hardening time.Originality/value–During 90 days’age,the electrical flux of the CA mortar gradually decreased with the increase of specimen thickness and the electrical flux of the specimens with the thickness of 54 mm was lower than 500 C.The impermeability and durability of the CA mortar could be improved by increasing the thickness of filling layer.The proposed method can provide reference for the further development and improvement of CRTS I and CRTS II type ballastless track in China. 展开更多
关键词 CA mortar Electric flux Compressive strength DENSITY
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Influence of Ultra Fine Glass Powder on the Properties and Microstructure of Mortars
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作者 Wei Chen Dingdan Liu Yue Liang 《Fluid Dynamics & Materials Processing》 EI 2024年第5期915-938,共24页
This study focuses on the effect of ultrafine waste glass powder on cement strength,gas permeability and pore structure.Varying contents were considered,with particle sizes ranging from 2 to 20μm.Moreover,alkali acti... This study focuses on the effect of ultrafine waste glass powder on cement strength,gas permeability and pore structure.Varying contents were considered,with particle sizes ranging from 2 to 20μm.Moreover,alkali activation was considered to ameliorate the reactivity and cementitious properties,which were assessed by using scanning electron microscopy(SEM),energy-dispersive X-ray spectroscopy(EDS),and specific surface area pore size distribution analysis.According to the results,without the addition of alkali activators,the performance of glass powder mortar decreases as the amount of glass powder increases,affecting various aspects such as strength and resistance to gas permeability.Only 5%glass powder mortar demonstrated a compressive strength at 60 days higher than that of the control group.However,adding alkali activator(CaO)during hydration ameliorated the hydration environment,increased the alkalinity of the composite system,activated the reactivity of glass powder,and enhanced the interaction of glass powder and pozzolanic reaction.In general,compared to ordinary cement mortar,alkali-activated glass powder mortar produces more hydration products,showcases elevated density,and exhibits improved gas resistance.Furthermore,alkali-activated glass powder mortar demonstrates an improvement in performance across various aspects as the content increases.At a substitution rate of 15%,the glass powder mortar reaches its optimal levels of strength and resistance to gas permeability,with a compressive strength increase ranging from 28.4%to 34%,and a gas permeation rate reduction between 51.8%and 66.7%. 展开更多
关键词 mortar waste glass powder alkali activation compressive strength gas permeability pore structure
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Clinical study of neutrophil-to-lymphocyte ratio and platelet-tolymphocyte ratio in hypertriglyceridemia-induced acute pancreatitis and acute biliary pancreatitis with persistent organ failure
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作者 Mu-Sen Xu Jia-Le Xu +5 位作者 Xin Gao Shao-Jian Mo Jia-Yu Xing Jia-Hang Liu Yan-Zhang Tian Xi-Feng Fu 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第6期1647-1659,共13页
BACKGROUND The neutrophil-to-lymphocyte ratio(NLR)and platelet-to-lymphocyte ratio(PLR)are novel inflammatory indicators that can be used to predict the severity and prognosis of various diseases.We categorize acute p... BACKGROUND The neutrophil-to-lymphocyte ratio(NLR)and platelet-to-lymphocyte ratio(PLR)are novel inflammatory indicators that can be used to predict the severity and prognosis of various diseases.We categorize acute pancreatitis by etiology into acute biliary pancreatitis(ABP)and hypertriglyceridemia-induced acute pancreatitis(HTGP).AIM To investigate the clinical significance of NLR and PLR in assessing persistent organ failure(POF)in HTGP and ABP.METHODS A total of 1450 patients diagnosed with acute pancreatitis(AP)for the first time at Shanxi Bethune Hospital between January 2012 and January 2023 were enrolled.The patients were categorized into two groups according to the etiology of AP:ABP in 530 patients and HTGP in 241 patients.We collected and compared the clinical data of the patients,including NLR,PLR,and AP prognostic scoring systems,within 48 h of hospital admission.RESULTS The NLR(9.1 vs 6.9,P<0.001)and PLR(203.1 vs 160.5,P<0.001)were significantly higher in the ABP group than in the HTGP group.In the HTGP group,both NLR and PLR were significantly increased in patients with severe AP and those with a SOFA score≥3.Likewise,in the ABP group,NLR and PLR were significantly elevated in patients with severe AP,modified computed tomography severity index score≥4,Japanese Severity Score≥3,and modified Marshall score≥2.Moreover,NLR and PLR showed predictive value for the development of POF in both the ABP and HTGP groups.CONCLUSION NLR and PLR vary between ABP and HTGP,are strongly associated with AP prognostic scoring systems,and have predictive potential for the occurrence of POF in both ABP and HTGP. 展开更多
关键词 Acute pancreatitis GALLSTONE HYPERTRIGLYCERIDEMIA Neutrophil-to-lymphocyte ratio Platelet-to-lymphocyte ratio Persistent organ failure
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Effect of length-width ratio of rounded rectangle aquaculture tank in dual-diagonal-inlet layout on hydrodynamic
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作者 Meng LI Xiaozhong REN +4 位作者 Shupeng DU Wei SUN Chenxu ZHAO Hangfei LIU Xianying SHI 《Journal of Oceanology and Limnology》 SCIE CAS CSCD 2024年第5期1695-1709,共15页
To adapt to the change of aquaculture workshop site,optimize the shape of aquaculture tanks and improve the utilization rate of breeding space,it is necessary to determine the appropriate length width ratio parameters... To adapt to the change of aquaculture workshop site,optimize the shape of aquaculture tanks and improve the utilization rate of breeding space,it is necessary to determine the appropriate length width ratio parameters of aquaculture tanks.In this paper,computational fluid dynamics(CFD)technology is adopted to study the flow field performance of aquaculture tanks with different L/B ratios(L:the length;B:the width,of aquaculture tank)and different jet direction conditions(lengthways jet and widthways jet).A three-dimensional numerical calculation model of turbulence in rounded rectangle aquaculture tanks in dual-diagonal-inlet layout was established.Jet directions are arranged lengthways and widthways,and the water flow velocity,resistance coefficient change,vorticity,etc.are analyzed under two working conditions.Results show that the flow field performance in aquaculture tank decreases with the increase of the L/B ratio.The flow field performed well when L/B was 1.0-1.3,sharply dropped at 1.4-1.6,and poor at 1.7-1.9.The results provided a theoretical basis for the design and optimization in flow field performance of the industrialized circulating aquaculture tanks. 展开更多
关键词 aquaculture tank length-width ratio computational fluid dynamic HYDRODYNAMIC
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Experimental Study of Local Scour Around Four Piles Under Different Attack Angles and Gap Ratios
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作者 LIU Ming-ming TANG Guo-qiang +1 位作者 JIN Xin GENG Shao-yang 《China Ocean Engineering》 SCIE EI CSCD 2024年第4期612-624,共13页
In an effort to investigate and quantify the patterns of local scour,researchers embarked on an in-depth study using a systematic experimental approach.The research focused on the effects of local scour around a set o... In an effort to investigate and quantify the patterns of local scour,researchers embarked on an in-depth study using a systematic experimental approach.The research focused on the effects of local scour around a set of four piles,each subjected to different hydromechanical conditions.In particular,this study aimed to determine how different attack angles—the angles at which the water flow impinges on the piles,and gap ratios—the ratios of the spacing between the piles to their diameters,influence the extent and nature of scour.A comprehensive series of 35 carefully designed experiments were orchestrated,each designed to dissect the nuances in how the gap ratio and attack angle might contribute to changes in the local scour observed at the base of pile groups.During these experimental trials,a wealth of local scour data were collected to support the analysis.These data included precise topographic profiles of the sediment bed around the pile groups,as well as detailed scour time histories showing the evolution of scour at strategic feature points throughout the test procedure.The analysis of the experimental data provided interesting insights.The study revealed that the interplay between the gap ratio and the attack angle had a pronounced influence on the scouring dynamics of the pile groups.One of the key observations was that the initial phases of scour,particularly within the first hour of water flow exposure,were characterized by a sharp increase in the scour depth occurring immediately in front of the piles.After this initial rapid development,the scour depth transitioned to a more gradual change rate.In contrast,the scour topography around the piles continuously evolved.This suggests that sediment displacement and the associated sculpting of the seabed around pile foundations are sustained and progressive processes,altering the underwater landscape over time.The results of this empirical investigation have significant implications for the design and construction of offshore multi-pile foundations,providing a critical reference for engineers and designers to estimate the expected scour depth around such structures,which is an integral part of decisions regarding foundation design,selection of structural materials,and implementation of scour protection measures. 展开更多
关键词 local scour PILES gap ratio attack angle
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Effects of the Water-Cement Ratio and the Molding Temperature on the Hydration Heat of Cement
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作者 代金鹏 HE Jie +1 位作者 WANG Qicai LOU Xuyu 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS CSCD 2024年第4期990-998,共9页
The effects of the water-cement ratio and the molding temperature on the hydration heat of cement were investigated with semi-adiabatic calorimetry.The specimens were prepared with water-cement ratios of 0.31,0.38,and... The effects of the water-cement ratio and the molding temperature on the hydration heat of cement were investigated with semi-adiabatic calorimetry.The specimens were prepared with water-cement ratios of 0.31,0.38,and 0.45,and the molding temperature was specified at 10 and 20℃.The experimental results show that,as the water-binder ratio increases,the value of the second temperature peak on the temperature curve of the cement paste decreases,and the age at which the peak appears is delayed.The higher the water-cement ratio,the higher the hydration heat release in the early period of cement hydration,but this trend reverses in the late period.There are intersection points of the total hydration heat curve of the cement pastes under the influence of the water-cement ratio,and this law can be observed at both molding temperatures.With the increase in the molding temperature,the age of the second temperature peak on the temperature curve of the cement paste will advance,but the temperature peak will decrease.The higher the molding temperature,the earlier the acceleration period of the cement hydration began,and the larger the hydration heat of the cement in the early stage,but the smaller the total heat in the late period.A subsection function calculation model of the hydration heat,which was based on the existing models,was proposed in order to predict the heat of the hydration of the concrete. 展开更多
关键词 semi-adiabatic calorimetry hydration heat water-cement ratio molding temperature MODELING
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