A simulation method is proposed to predict the motion artifacts of plasma display panels (PDPs). The method simulates the behavior of the human vision system when perceiving moving objects. The simulation is based o...A simulation method is proposed to predict the motion artifacts of plasma display panels (PDPs). The method simulates the behavior of the human vision system when perceiving moving objects. The simulation is based on the measured temporal light properties of the display for each gray level and each phosphor. Both the effect of subfield arrangement and phosphor decay are involved. A novel algorithm is proposed to improve the calculation speed. The simulation model manages to predict the appearance of the motion image perceived by a human with a still image. The results are validated by a set of perceptual evaluation experiments. This rapid and accurate prediction of motion artifacts enables objective characterization of the PDP performance in this aspect.展开更多
Objective :To investigate the influences of motion artifacts on three-dimensional (3D) reconstruction volume and conformal radiotherapy planning. Methods: A phantom which can mimic the clip motion of lung tumor al...Objective :To investigate the influences of motion artifacts on three-dimensional (3D) reconstruction volume and conformal radiotherapy planning. Methods: A phantom which can mimic the clip motion of lung tumor along the cranial-caudal direction is constructed by step motor, small ball of polyethylene and potato. Ten different scan protocols were set and CT data of the phantom were acquired by using a commercial GE LightSpeedl6 CT scanner. The 3D reconstruction of the CT data was implemented by adopting volume-rendering technology of GE AdvantageSim 6.0 system. The reconstructed volumes of each target in different scan protocols were measured through 3D measuring tools. Thus, relative deviations of the reconstruction volumes between moving targets and static ones were determined. The three-dimensional conformal radiation therapy (3D- CRT) plans and conformal fields were created and compared for a static/moving target with the WiMRT treatment planning system (TPS). Results:For a static target, there was no obvious difference among the 3D reconstruction volumes when the CT data were acquired with different pitches and slices. The appearance of 3D reconstruction volume and 3D conformal field of a moving target was quite different from that of static one. The maximum relative deviation is nearly 90% for a moving target scanned with different scan protocols. The relative deviations are variable among the different targets, about from -39.8% to 89.5% for a smaller target and from - 18.4% to 20.5% for a larger one. Conclusion :The motion artifacts have great effects on 3 D-CRT planning and reconstruction volume, which will greatly induce distorted conformal radiation fields and false DVHs for a moving target.展开更多
During the process of magnetic resonance imaging (MRI), the patient motion causes phase errors in collected signals and induces motion artifacts in the reconstructed image. Severe artifacts interfere with the focus ...During the process of magnetic resonance imaging (MRI), the patient motion causes phase errors in collected signals and induces motion artifacts in the reconstructed image. Severe artifacts interfere with the focus location. Because the genetic algorithm (GA) has characteristics of parallel, random and adaptive stochastic searching, a correction method of motion artifacts is presented based on the algorithm. The method can correct the phase error in K-space signals step by step. Experiments show that the motion artifacts in MRI can be effectively suppressed by using the method.展开更多
This review paper aims to summarize cardiac CT blooming artifacts,how they present clinically and what their root causes and potential solutions are.A literature survey was performed covering any publications with a s...This review paper aims to summarize cardiac CT blooming artifacts,how they present clinically and what their root causes and potential solutions are.A literature survey was performed covering any publications with a specific interest in calcium blooming and stent blooming in cardiac CT.The claims from literature are compared and interpreted,aiming at narrowing down the root causes and most promising solutions for blooming artifacts.More than 30 journal publications were identified with specific relevance to blooming artifacts.The main reported causes of blooming artifacts are the partial volume effect,motion artifacts and beam hardening.The proposed solutions are classified as high-resolution CT hardware,high-resolution CT reconstruction,subtraction techniques and post-processing techniques,with a special emphasis on deep learning(DL)techniques.The partial volume effect is the leading cause of blooming artifacts.The partial volume effect can be minimized by increasing the CT spatial resolution through higherresolution CT hardware or advanced high-resolution CT reconstruction.In addition,DL techniques have shown great promise to correct for blooming artifacts.A combination of these techniques could avoid repeat scans for subtraction techniques.展开更多
Noninvasive techniques,surface electromyography(sEMG)in particular,are being increasingly employed for assessing muscle activity.In these studies,local oxygen consumption and muscle metabolism are of great interest.Me...Noninvasive techniques,surface electromyography(sEMG)in particular,are being increasingly employed for assessing muscle activity.In these studies,local oxygen consumption and muscle metabolism are of great interest.Measurements can be performed noninvasively using optics-based methods such as near-infrared spectroscopy(NIRS).By combining energy con-sumption data provided by NIRS with muscle level activation data from sEMG,we may gain an insight into the metabolic and functional characteristics of muscle tissue.However,muscle mo-tion may induce artifacts into EMG and NIRS.Thus,the inclusion of simultaneous motion measurements using accelerometers(ACMs)enhances possibilities to perceive the effects of motion on NIRS and EMG signals.This paper reviews the current state of noninvasive EMG and NIRS-based methods used to study muscle function.In addition,we built a combined sEMG/NIRS/ACM sensor to perform simultaneous measurements for static and dynamic exercises of a biceps brachii muscle.Further,we discuss the effect of muscle motion in response of NIRS and EMG when measured noninva-sively.Based on our preliminary studies,both NIRS and EMG supply specific information on muscle activation,but their signal responses also showed similarities with acceleration signals which,in this case,were supposed to be solely sensitive to motions.展开更多
AIM: To compare the clinical performance of 4 spectraldomain(SD) optical coherence tomography angiography(OCTA) systems: AngioVueTM, AngioPlexTM, Spectralis? OCTA, AngioScan, and 1 swept-source(SS) OCTA SS OC...AIM: To compare the clinical performance of 4 spectraldomain(SD) optical coherence tomography angiography(OCTA) systems: AngioVueTM, AngioPlexTM, Spectralis? OCTA, AngioScan, and 1 swept-source(SS) OCTA SS OCT AngioTM. METHODS: Twenty-seven undilated right eyes of 27 participants underwent OCTA examination using five different systems respectively for both 3×3 and 6×6 mm^2 scan pattern(Spectralis OCTA for 3×3 mm^2 scan only). Image quality, including vessel valid visibility and the number of motion artifacts, and acquisition time were evaluated. Repeated measures analysis of variance(ANOVA) with Bonferroni's post-test and Friedman test with Dunn's posttest were used to compare measurements.RESULTS: The age of the subjects was 28.19±5.55 y(range, 23-49 y). The spherical equivalent refraction was-2.55±1.84 D(range, 0.00 to-5.25 D). Significant difference was observed in the evaluation of vessel valid visibility(Angio Vue the highest: 0.111±0.031 for 3×3 mm^2 scan and 0.128±0.020 for 6×6 mm^2 scan), number of motion artifacts(AngioVue the fewest: 0.778±1.086 for 3×3 mm^2 scan and 0.333±0.620 for 6×6 mm^2 scan) and acquisition time(AngioPlex the shortest: 8.537±1.921 s for 3×3 mm^2 scan and 8.298±1.741 s for 6×6 mm^2 scan; all P〈0.001). CONCLUSION: There is poor agreement of measurements among systems. AngioVue provides images with the highest vessel valid visibility and the fewest motion artifacts. AngioPlex achieves the shortest acquisition.展开更多
Objective:To investigate the feasibility of a 4D-CT reconstruction method based on the similarity principle of spatial adjacent images and mutual information measure. Methods:A motor driven sinusoidal motion platform ...Objective:To investigate the feasibility of a 4D-CT reconstruction method based on the similarity principle of spatial adjacent images and mutual information measure. Methods:A motor driven sinusoidal motion platform made in house was used to create one-dimensional periodical motion that was along the longitudinal axis of the CT couch. The amplitude of sinusoidal motion was set to an amplitude of ±1 cm. The period of the motion was adjustable and set to 3.5 s. Phantom objects of two eggs were placed in a Styrofoam block, which in turn were placed on the motion platform. These objects were used to simulate volumes of interest undergoing ideal periodic motion. CT data of static phantom were acquired using a multi-slice general electric (GE) LightSpeed 16-slice CT scanner in an axial mode. And the CT data of periodical motion phantom were acquired in an axial and cine-mode scan. A software program was developed by using VC++ and VTK software tools to resort the CT data and reconstruct the 4D-CT. Then all of the CT data with same phase were sorted by the program into the same series based on the similarity principle of spatial adjacent images and mutual information measure among them, and 3D reconstruction of different phase CT data were completed by using the software. Results:All of the CT data were sorted accurately into different series based on the similarity principle of spatial adjacent images and mutual information measures among them. Compared with the unsorted CT data, the motion artifacts in the 3D reconstruction of sorted CT data were reduced significantly, and all of the sorted CT series result in a 4D-CT that reflected the characteristic of the periodical motion phantom. Conclusion:Time-resolved 4D-CT reconstruction can be implemented with any general multi-slice CT scanners based on the similarity principle of spatial adjacent images and mutual information measure.The process of the 4D-CT data acquisition and reconstruction were not restricted to the hardware or software of the CT scanner and has the feasibility ,which extensive applicability.展开更多
To date,the clinical use of functional near-infrared spectroscopy(NIRS)to detect cerebral ischemia has been largely limited to surgical settings,where motion artifacts are minimal.In this study,we present novel techni...To date,the clinical use of functional near-infrared spectroscopy(NIRS)to detect cerebral ischemia has been largely limited to surgical settings,where motion artifacts are minimal.In this study,we present novel techniques to address the challenges of using NIRS to monitor ambu-latory patients with kidney disease during approximately eight hours of hemodialysis(HD)treatment.People with end-stage kidney disease who require HD are at higher risk for cognitive impairment and dementia than age-matched controls.Recent studies have suggested that HD-related declines in cerebral blood flow might explain some of the adverse outcomes of HD treatment.However,there are currently no established paradigms for monitoring cerebral per-fusion in real-time during HD treatment.In this study,we used NIRS to assess cerebral hemo-dynamic responses among 95 prevalent HD patients during two consecutive HD treatments.We observed substantial signal attenuation in our predominantly Black patient cohort that required probe modifications.We also observed consistent motion artifacts that we addressed by devel-oping a novel NIRS methodology,called the HD cerebral oxygen demand algorithm(HD-CODA),to identify episodes when cerebral oxygen demand might be outpacing supply during HD treatment.We then examined the association between a summary measure of time spent in cerebral deoxygenation,derived using the HD-CODA,and hemodynamic and treatment-related variables.We found that this summary measure was associated with intradialytic mean arterial pressure,heart rate,and volume removal.Future studies should use the HD-CODA to implement studies of real-time NIRS monitoring for incident dialysis patients,over longer time frames,and in other dialysis modalities.展开更多
This paper gives an efficient approach to reconstruct moving multiple objects (multi-object). Each object has independently rigid motion which includes translation and rotation. The traditional FBP algorithm can res...This paper gives an efficient approach to reconstruct moving multiple objects (multi-object). Each object has independently rigid motion which includes translation and rotation. The traditional FBP algorithm can resolve the one-object motion problem rather well. However, it suffers from perceptible motion artifacts in multi-object cases. This paper proposes a new motion-compensated reconstruction approach with a pdori knowledge of the rigid motion model. Both an FBP-type and an ART-type algorithm were derived. In an effort to evaluate the proposed algorithms, we have performed numerical studies by using different rigid motion models. Quantitative results demonstrate that the proposed FBP-type and ART-type algorithms can recon- struct multi-object free of motion artifacts.展开更多
Purpose:Motion artifacts induced by breathing variations are common in 4D-MRI images.This study aims to reduce the motion artifacts by developing a novel,robust 4D-MRI sorting method based on anatomic feature matching...Purpose:Motion artifacts induced by breathing variations are common in 4D-MRI images.This study aims to reduce the motion artifacts by developing a novel,robust 4D-MRI sorting method based on anatomic feature matching and applicable in both cine and sequential acquisition.Method:The proposed method uses the diaphragm as the anatomic feature to guide the sorting of 4D-MRI images.Initially,both abdominal 2D sagittal cine MRI images and axial MRI images were acquired.The sagittal cine MRI images were divided into 10 phases as ground truth.Next,the phase of each axial MRI image is determined by matching its diaphragm position in the intersection plane to the ground truth cine MRI.Then,those matched phases axial images were sorted into 10-phase bins which were identical to the ground truth cine images.Finally,10-phase 4D-MRI were reconstructed from these sorted axial images.The accuracy of reconstructed 4D-MRI data was evaluated by comparing with the ground truth using the 4D eXtended Cardiac Torso(XCAT)digital phantom.The effects of breathing signal,including both regular(cosine function)and irregular(patient data)in both axial cine and sequential scanning modes,on reconstruction accuracy were investigated by calculating total relative error(TRE)of the 4D volumes,Volume-Percent-Difference(VPD)and Center-of-Mass-Shift(COMS)of the estimated tumor volume,compared with the ground truth XCAT images.Results:In both scanning modes,reconstructed 4D-MRI images matched well with ground truth with minimal motion artifacts.The averaged TRE of the 4D volume,VPD and COMS of the EOE phase in both scanning modes are 0.32%/1.20%/0.05 mm for regular breathing,and 1.13%/4.26%/0.21 mm for patient irregular breathing.Conclusion:The preliminary evaluation results illustrated the feasibility of the robust 4D-MRI sorting method based on anatomic feature matching.This method provides improved image quality with reduced motion artifacts for both cine and sequential scanning modes.展开更多
Laser speckle imaging is a common technique to monitor blood flow.The fluctuations in speckle intensity can be related to the blood flow by calculating the speckle contrast,the ratio between the standard deviation of ...Laser speckle imaging is a common technique to monitor blood flow.The fluctuations in speckle intensity can be related to the blood flow by calculating the speckle contrast,the ratio between the standard deviation of speckle fluctuations and the average intensity.However,this simple statistic calculation is easily affected by motion artifacts.In this study,we applied sample entropy analysis instead of calculating standard deviations of the speckle fluctuations.Similar to the traditional method,sample entropy-based speckle contrast increases linearly with flow rate but was shown to be more immune to sudden movements during an upper arm occlusion test.展开更多
A numerical method that compensates image distortions caused by random fluctuations of the distance to an object in spectral-domain optical coherence tomography(SD OCT)has been proposed and verified experimentally.The...A numerical method that compensates image distortions caused by random fluctuations of the distance to an object in spectral-domain optical coherence tomography(SD OCT)has been proposed and verified experimentally.The proposed method is based on the analysis of the phase shifts between adjacent scans that are caused by micrometer-scale displacements and the subsequent compensation for the displacements through phase-frequency correction in the spectral space.The efficiency of the method is demonstrated in model experiments with harmonic and random movements of a scattering object as well as during in vivo imaging of the retina of the human eye.展开更多
Electrocardiogram(ECG) can be used as a valid way for diagnosing heart disease.To fulfill ECG processing in wearable devices by reducing computation complexity and hardware cost,two kinds of adaptive filters are des...Electrocardiogram(ECG) can be used as a valid way for diagnosing heart disease.To fulfill ECG processing in wearable devices by reducing computation complexity and hardware cost,two kinds of adaptive filters are designed to perform QRS complex detection and motion artifacts removal,respectively.The proposed design achieves a sensitivity of 99.49% and a positive predictivity of 99.72%,tested under the MIT-BIH ECG database.The proposed design is synthesized under the SMIC 65-nm CMOS technology and verified by post-synthesis simulation.Experimental results show that the power consumption and area cost of this design are of 160 μW and 1.09×10^5 μm^2,respectively.展开更多
文摘A simulation method is proposed to predict the motion artifacts of plasma display panels (PDPs). The method simulates the behavior of the human vision system when perceiving moving objects. The simulation is based on the measured temporal light properties of the display for each gray level and each phosphor. Both the effect of subfield arrangement and phosphor decay are involved. A novel algorithm is proposed to improve the calculation speed. The simulation model manages to predict the appearance of the motion image perceived by a human with a still image. The results are validated by a set of perceptual evaluation experiments. This rapid and accurate prediction of motion artifacts enables objective characterization of the PDP performance in this aspect.
基金Grant sponsor:Guangzhou Municipal Medicin &Health ProgramGrant number:2006-YB-177
文摘Objective :To investigate the influences of motion artifacts on three-dimensional (3D) reconstruction volume and conformal radiotherapy planning. Methods: A phantom which can mimic the clip motion of lung tumor along the cranial-caudal direction is constructed by step motor, small ball of polyethylene and potato. Ten different scan protocols were set and CT data of the phantom were acquired by using a commercial GE LightSpeedl6 CT scanner. The 3D reconstruction of the CT data was implemented by adopting volume-rendering technology of GE AdvantageSim 6.0 system. The reconstructed volumes of each target in different scan protocols were measured through 3D measuring tools. Thus, relative deviations of the reconstruction volumes between moving targets and static ones were determined. The three-dimensional conformal radiation therapy (3D- CRT) plans and conformal fields were created and compared for a static/moving target with the WiMRT treatment planning system (TPS). Results:For a static target, there was no obvious difference among the 3D reconstruction volumes when the CT data were acquired with different pitches and slices. The appearance of 3D reconstruction volume and 3D conformal field of a moving target was quite different from that of static one. The maximum relative deviation is nearly 90% for a moving target scanned with different scan protocols. The relative deviations are variable among the different targets, about from -39.8% to 89.5% for a smaller target and from - 18.4% to 20.5% for a larger one. Conclusion :The motion artifacts have great effects on 3 D-CRT planning and reconstruction volume, which will greatly induce distorted conformal radiation fields and false DVHs for a moving target.
文摘During the process of magnetic resonance imaging (MRI), the patient motion causes phase errors in collected signals and induces motion artifacts in the reconstructed image. Severe artifacts interfere with the focus location. Because the genetic algorithm (GA) has characteristics of parallel, random and adaptive stochastic searching, a correction method of motion artifacts is presented based on the algorithm. The method can correct the phase error in K-space signals step by step. Experiments show that the motion artifacts in MRI can be effectively suppressed by using the method.
基金Research reported in this publication was supported by the National Heart,Lung,And Blood Institute of the National Institutes of Health,No.R01HL151561The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.
文摘This review paper aims to summarize cardiac CT blooming artifacts,how they present clinically and what their root causes and potential solutions are.A literature survey was performed covering any publications with a specific interest in calcium blooming and stent blooming in cardiac CT.The claims from literature are compared and interpreted,aiming at narrowing down the root causes and most promising solutions for blooming artifacts.More than 30 journal publications were identified with specific relevance to blooming artifacts.The main reported causes of blooming artifacts are the partial volume effect,motion artifacts and beam hardening.The proposed solutions are classified as high-resolution CT hardware,high-resolution CT reconstruction,subtraction techniques and post-processing techniques,with a special emphasis on deep learning(DL)techniques.The partial volume effect is the leading cause of blooming artifacts.The partial volume effect can be minimized by increasing the CT spatial resolution through higherresolution CT hardware or advanced high-resolution CT reconstruction.In addition,DL techniques have shown great promise to correct for blooming artifacts.A combination of these techniques could avoid repeat scans for subtraction techniques.
文摘Noninvasive techniques,surface electromyography(sEMG)in particular,are being increasingly employed for assessing muscle activity.In these studies,local oxygen consumption and muscle metabolism are of great interest.Measurements can be performed noninvasively using optics-based methods such as near-infrared spectroscopy(NIRS).By combining energy con-sumption data provided by NIRS with muscle level activation data from sEMG,we may gain an insight into the metabolic and functional characteristics of muscle tissue.However,muscle mo-tion may induce artifacts into EMG and NIRS.Thus,the inclusion of simultaneous motion measurements using accelerometers(ACMs)enhances possibilities to perceive the effects of motion on NIRS and EMG signals.This paper reviews the current state of noninvasive EMG and NIRS-based methods used to study muscle function.In addition,we built a combined sEMG/NIRS/ACM sensor to perform simultaneous measurements for static and dynamic exercises of a biceps brachii muscle.Further,we discuss the effect of muscle motion in response of NIRS and EMG when measured noninva-sively.Based on our preliminary studies,both NIRS and EMG supply specific information on muscle activation,but their signal responses also showed similarities with acceleration signals which,in this case,were supposed to be solely sensitive to motions.
基金Supported by National Key Research and Development Program for Precision Medicine of China (No.2016YFC0904800)
文摘AIM: To compare the clinical performance of 4 spectraldomain(SD) optical coherence tomography angiography(OCTA) systems: AngioVueTM, AngioPlexTM, Spectralis? OCTA, AngioScan, and 1 swept-source(SS) OCTA SS OCT AngioTM. METHODS: Twenty-seven undilated right eyes of 27 participants underwent OCTA examination using five different systems respectively for both 3×3 and 6×6 mm^2 scan pattern(Spectralis OCTA for 3×3 mm^2 scan only). Image quality, including vessel valid visibility and the number of motion artifacts, and acquisition time were evaluated. Repeated measures analysis of variance(ANOVA) with Bonferroni's post-test and Friedman test with Dunn's posttest were used to compare measurements.RESULTS: The age of the subjects was 28.19±5.55 y(range, 23-49 y). The spherical equivalent refraction was-2.55±1.84 D(range, 0.00 to-5.25 D). Significant difference was observed in the evaluation of vessel valid visibility(Angio Vue the highest: 0.111±0.031 for 3×3 mm^2 scan and 0.128±0.020 for 6×6 mm^2 scan), number of motion artifacts(AngioVue the fewest: 0.778±1.086 for 3×3 mm^2 scan and 0.333±0.620 for 6×6 mm^2 scan) and acquisition time(AngioPlex the shortest: 8.537±1.921 s for 3×3 mm^2 scan and 8.298±1.741 s for 6×6 mm^2 scan; all P〈0.001). CONCLUSION: There is poor agreement of measurements among systems. AngioVue provides images with the highest vessel valid visibility and the fewest motion artifacts. AngioPlex achieves the shortest acquisition.
基金Guangzhou Municipal Medicine &Health ProgramGrant number:2006-YB-177+1 种基金Guangdong Province Medicine Scientific Research ProgramGrant number:A2007290
文摘Objective:To investigate the feasibility of a 4D-CT reconstruction method based on the similarity principle of spatial adjacent images and mutual information measure. Methods:A motor driven sinusoidal motion platform made in house was used to create one-dimensional periodical motion that was along the longitudinal axis of the CT couch. The amplitude of sinusoidal motion was set to an amplitude of ±1 cm. The period of the motion was adjustable and set to 3.5 s. Phantom objects of two eggs were placed in a Styrofoam block, which in turn were placed on the motion platform. These objects were used to simulate volumes of interest undergoing ideal periodic motion. CT data of static phantom were acquired using a multi-slice general electric (GE) LightSpeed 16-slice CT scanner in an axial mode. And the CT data of periodical motion phantom were acquired in an axial and cine-mode scan. A software program was developed by using VC++ and VTK software tools to resort the CT data and reconstruct the 4D-CT. Then all of the CT data with same phase were sorted by the program into the same series based on the similarity principle of spatial adjacent images and mutual information measure among them, and 3D reconstruction of different phase CT data were completed by using the software. Results:All of the CT data were sorted accurately into different series based on the similarity principle of spatial adjacent images and mutual information measures among them. Compared with the unsorted CT data, the motion artifacts in the 3D reconstruction of sorted CT data were reduced significantly, and all of the sorted CT series result in a 4D-CT that reflected the characteristic of the periodical motion phantom. Conclusion:Time-resolved 4D-CT reconstruction can be implemented with any general multi-slice CT scanners based on the similarity principle of spatial adjacent images and mutual information measure.The process of the 4D-CT data acquisition and reconstruction were not restricted to the hardware or software of the CT scanner and has the feasibility ,which extensive applicability.
基金The study was funded by the Commonwealth Universal Research Enhancement Grant Program(CURE)MNH is supported by grants from the National Institutes of Health(NIH):K23DK105207 and R01DK124388.
文摘To date,the clinical use of functional near-infrared spectroscopy(NIRS)to detect cerebral ischemia has been largely limited to surgical settings,where motion artifacts are minimal.In this study,we present novel techniques to address the challenges of using NIRS to monitor ambu-latory patients with kidney disease during approximately eight hours of hemodialysis(HD)treatment.People with end-stage kidney disease who require HD are at higher risk for cognitive impairment and dementia than age-matched controls.Recent studies have suggested that HD-related declines in cerebral blood flow might explain some of the adverse outcomes of HD treatment.However,there are currently no established paradigms for monitoring cerebral per-fusion in real-time during HD treatment.In this study,we used NIRS to assess cerebral hemo-dynamic responses among 95 prevalent HD patients during two consecutive HD treatments.We observed substantial signal attenuation in our predominantly Black patient cohort that required probe modifications.We also observed consistent motion artifacts that we addressed by devel-oping a novel NIRS methodology,called the HD cerebral oxygen demand algorithm(HD-CODA),to identify episodes when cerebral oxygen demand might be outpacing supply during HD treatment.We then examined the association between a summary measure of time spent in cerebral deoxygenation,derived using the HD-CODA,and hemodynamic and treatment-related variables.We found that this summary measure was associated with intradialytic mean arterial pressure,heart rate,and volume removal.Future studies should use the HD-CODA to implement studies of real-time NIRS monitoring for incident dialysis patients,over longer time frames,and in other dialysis modalities.
基金Supported by the National Natural Science Foundation of China (Nos.10575059,60871084,and 10905030)
文摘This paper gives an efficient approach to reconstruct moving multiple objects (multi-object). Each object has independently rigid motion which includes translation and rotation. The traditional FBP algorithm can resolve the one-object motion problem rather well. However, it suffers from perceptible motion artifacts in multi-object cases. This paper proposes a new motion-compensated reconstruction approach with a pdori knowledge of the rigid motion model. Both an FBP-type and an ART-type algorithm were derived. In an effort to evaluate the proposed algorithms, we have performed numerical studies by using different rigid motion models. Quantitative results demonstrate that the proposed FBP-type and ART-type algorithms can recon- struct multi-object free of motion artifacts.
基金This research was partly supported by research grants(NIH R01 EB028324,NIH R01 CA226899,GRF 151021/18M,GRF 151022/19M and HMRF 06173276).
文摘Purpose:Motion artifacts induced by breathing variations are common in 4D-MRI images.This study aims to reduce the motion artifacts by developing a novel,robust 4D-MRI sorting method based on anatomic feature matching and applicable in both cine and sequential acquisition.Method:The proposed method uses the diaphragm as the anatomic feature to guide the sorting of 4D-MRI images.Initially,both abdominal 2D sagittal cine MRI images and axial MRI images were acquired.The sagittal cine MRI images were divided into 10 phases as ground truth.Next,the phase of each axial MRI image is determined by matching its diaphragm position in the intersection plane to the ground truth cine MRI.Then,those matched phases axial images were sorted into 10-phase bins which were identical to the ground truth cine images.Finally,10-phase 4D-MRI were reconstructed from these sorted axial images.The accuracy of reconstructed 4D-MRI data was evaluated by comparing with the ground truth using the 4D eXtended Cardiac Torso(XCAT)digital phantom.The effects of breathing signal,including both regular(cosine function)and irregular(patient data)in both axial cine and sequential scanning modes,on reconstruction accuracy were investigated by calculating total relative error(TRE)of the 4D volumes,Volume-Percent-Difference(VPD)and Center-of-Mass-Shift(COMS)of the estimated tumor volume,compared with the ground truth XCAT images.Results:In both scanning modes,reconstructed 4D-MRI images matched well with ground truth with minimal motion artifacts.The averaged TRE of the 4D volume,VPD and COMS of the EOE phase in both scanning modes are 0.32%/1.20%/0.05 mm for regular breathing,and 1.13%/4.26%/0.21 mm for patient irregular breathing.Conclusion:The preliminary evaluation results illustrated the feasibility of the robust 4D-MRI sorting method based on anatomic feature matching.This method provides improved image quality with reduced motion artifacts for both cine and sequential scanning modes.
基金GIST Research Institute(GRI)funded by GIST in 2019 and 2020Brain Research Program(2016M3C7A1905475)+1 种基金Basic Research Program(2018R1A2B6006797)through the National Research Foundation of Korea(NRF)funded by Ministry of Science and ICTKBRI basic research program through Korea Brain Research Institute funded by Ministry of Science and ICT(21-BR-03-05)。
文摘Laser speckle imaging is a common technique to monitor blood flow.The fluctuations in speckle intensity can be related to the blood flow by calculating the speckle contrast,the ratio between the standard deviation of speckle fluctuations and the average intensity.However,this simple statistic calculation is easily affected by motion artifacts.In this study,we applied sample entropy analysis instead of calculating standard deviations of the speckle fluctuations.Similar to the traditional method,sample entropy-based speckle contrast increases linearly with flow rate but was shown to be more immune to sudden movements during an upper arm occlusion test.
基金the State task for IAP RAS(project No.0035-2019-0013)in part of method development by the Russian scientific foundation(project No.17-15-01507)in part of model experiments and setup creatingthe Russian Federal target program(project 14.610.21.0014 unique No.RFMEFI61017X0014)in part of retinal imaging experiments.
文摘A numerical method that compensates image distortions caused by random fluctuations of the distance to an object in spectral-domain optical coherence tomography(SD OCT)has been proposed and verified experimentally.The proposed method is based on the analysis of the phase shifts between adjacent scans that are caused by micrometer-scale displacements and the subsequent compensation for the displacements through phase-frequency correction in the spectral space.The efficiency of the method is demonstrated in model experiments with harmonic and random movements of a scattering object as well as during in vivo imaging of the retina of the human eye.
基金supported by the National Natural Science Foundation of China(Nos.61574040,61234002,61525401)
文摘Electrocardiogram(ECG) can be used as a valid way for diagnosing heart disease.To fulfill ECG processing in wearable devices by reducing computation complexity and hardware cost,two kinds of adaptive filters are designed to perform QRS complex detection and motion artifacts removal,respectively.The proposed design achieves a sensitivity of 99.49% and a positive predictivity of 99.72%,tested under the MIT-BIH ECG database.The proposed design is synthesized under the SMIC 65-nm CMOS technology and verified by post-synthesis simulation.Experimental results show that the power consumption and area cost of this design are of 160 μW and 1.09×10^5 μm^2,respectively.