In addressing the challenge of motion artifacts in Positron Emission Tomography (PET) lung scans, our studyintroduces the Triple Equivariant Motion Transformer (TEMT), an innovative, unsupervised, deep-learningbasedfr...In addressing the challenge of motion artifacts in Positron Emission Tomography (PET) lung scans, our studyintroduces the Triple Equivariant Motion Transformer (TEMT), an innovative, unsupervised, deep-learningbasedframework for efficient respiratory motion correction in PET imaging. Unlike traditional techniques,which segment PET data into bins throughout a respiratory cycle and often face issues such as inefficiency andoveremphasis on certain artifacts, TEMT employs Convolutional Neural Networks (CNNs) for effective featureextraction and motion decomposition.TEMT’s unique approach involves transforming motion sequences into Liegroup domains to highlight fundamental motion patterns, coupled with employing competitive weighting forprecise target deformation field generation. Our empirical evaluations confirm TEMT’s superior performancein handling diverse PET lung datasets compared to existing image registration networks. Experimental resultsdemonstrate that TEMT achieved Dice indices of 91.40%, 85.41%, 79.78%, and 72.16% on simulated geometricphantom data, lung voxel phantom data, cardiopulmonary voxel phantom data, and clinical data, respectively. Tofacilitate further research and practical application, the TEMT framework, along with its implementation detailsand part of the simulation data, is made publicly accessible at https://github.com/yehaowei/temt.展开更多
Objective To observe the clinical application value of total free-breathing cardiac MR(CMR)examination preliminarily.Methods Two patients who underwent CMR scanning under free-breathing state,including cine,motion cor...Objective To observe the clinical application value of total free-breathing cardiac MR(CMR)examination preliminarily.Methods Two patients who underwent CMR scanning under free-breathing state,including cine,motion correction T1 and T2 mapping,blood flow imaging,and late gadolinium enhancement scanning were retrospectively enrolled,and the qualities of the above images were evaluated and compared with that of conventional CMR images under breath-holding state.Results No significant difference of imaging quality was found between total free-breathing and conventional breath-holding CMR.The differences of left ventricular ejection fraction,cardiac output,left ventricular end-diastolic volume index and left ventricular mass measured based on CMR images under different breath conditions were limited.Conclusion Total free-breathing CMR was feasible in clinical practice,which could provide"one-stop"evaluation of cardiac structure,function and myocardial histological characteristics,hence having promising clinical prospects.展开更多
A flux system deployed on a moored buoy has been described, which is capable of directly estimating the airsea fluxes after removing the contamination in the signal due to buoy motion. A triple loop fitting method has...A flux system deployed on a moored buoy has been described, which is capable of directly estimating the airsea fluxes after removing the contamination in the signal due to buoy motion. A triple loop fitting method has been demonstrated for determining the three angular offsets between measurement axes of the sonic anemometer and motion pack. The data collected in an experiment in the Northern Huanghai Sea is used to correct the three sonic anemometer measurements of turbulent wind for buoy motion. The effective removal of wave-scale motion from the spectra and cospectra are demonstrated. Estimates of along-wind momentum flux, sensible heat flux and latent heat flux calculated by the eddy correlation method based on data obtained by sonic anemometer 81000V are shown to be in the same trend and scale with those determined by the bulk aerodynamic method after motion correction. The motion correction not only greatly improve the estimation of the momentum flux but also has a great impact on the calculated sensible heat flux.展开更多
In this study,we propose a deep-learning-based method to correct motion artifacts in optical resolution photoacoustic microscopy(OR-PAM).The method is a convolutional neural network that establishes an end-to-end map ...In this study,we propose a deep-learning-based method to correct motion artifacts in optical resolution photoacoustic microscopy(OR-PAM).The method is a convolutional neural network that establishes an end-to-end map from input raw data with motion artifacts to output corrected images.First,we performed simulation studies to evaluate the feasibility and effectiveness of the proposed method.Second,we employed this method to process images of rat brain vessels with multiple motion artifacts to evaluate its performance for in vivo applications.The results demonstrate that this method works well for both large blood vessels and capillary networks.In comparison with traditional methods,the proposed method in this study can be easily modified to satisfy different scenarios of motion corrections in OR-PAM by revising the training sets.展开更多
Precise measurements of the CO2 gas transfer across the air-sea interface provide a better under- standing of the global carbon cycle. The air-sea CO2 fluxes are obtained by the eddy covariance method and the bulk met...Precise measurements of the CO2 gas transfer across the air-sea interface provide a better under- standing of the global carbon cycle. The air-sea CO2 fluxes are obtained by the eddy covariance method and the bulk method from a buoy observation in the northern Huanghai sea. The effects of buoy motion on flux calculated by the eddy covariance method are demonstrated. The research shows that a motion correction can improve the correlation coefficient between the C02 fluxes esti- mated from two different levels. Without the CO2-H20 cross-correlation correction which is termed as PKT correction, the air-sea CO2 fluxes estimated by eddy covariance method using the motion corrected data are nearly an order of magnitude larger than those estimated by the bulk method. After the CO2-H20 cross-correlation correction, some eddy covariance CO2 fluxes indeed become closer to the bulk CO2 flux, whereas some are overcorrected which are in response to small water vapor flux.展开更多
Respiratory motion is a major factor that affects the quality of PET images of the thoracic area. The diaphragm moves about 15–20 mm due to respiratory motion, which substantially degrades the effective spatial resol...Respiratory motion is a major factor that affects the quality of PET images of the thoracic area. The diaphragm moves about 15–20 mm due to respiratory motion, which substantially degrades the effective spatial resolution of PET. In this paper, a gated acquisition method is used to correct the motion effects. In this method, an improved demons algorithm is proposed to align the gated images. The experimental results show that the quality of PET images is significantly improved when using our improved method and the proposed method has a faster convergence rate than the original demons algorithm.展开更多
A numerical method that compensates image distortions caused by random fluctuations of the distance to an object in spectral-domain optical coherence tomography(SD OCT)has been proposed and verified experimentally.The...A numerical method that compensates image distortions caused by random fluctuations of the distance to an object in spectral-domain optical coherence tomography(SD OCT)has been proposed and verified experimentally.The proposed method is based on the analysis of the phase shifts between adjacent scans that are caused by micrometer-scale displacements and the subsequent compensation for the displacements through phase-frequency correction in the spectral space.The efficiency of the method is demonstrated in model experiments with harmonic and random movements of a scattering object as well as during in vivo imaging of the retina of the human eye.展开更多
This Letter proposes a coordinate difference homogenization matching method to solve motion influence in three-dimensional(3D) range-intensity correlation laser imaging. Firstly, features and feature pairs of gate i...This Letter proposes a coordinate difference homogenization matching method to solve motion influence in three-dimensional(3D) range-intensity correlation laser imaging. Firstly, features and feature pairs of gate images are obtained by speeded-up robust figures and bi-directional feature matching methods. The original mean value of the feature-pair coordinate differences is calculated. Comparing the coordinate differences with the original mean value, the wrong feature pairs are removed, and then an optimized mean value is updated. The final feature-pair coordinates are re-registered based on the updated mean value. Thus, an accurate transformation is established to rectify motion gate images for 3D reconstruction. In the experiment, a 3D image of a tower at 780 m is successfully captured by our laser gated imaging system on a pan-tilt device.展开更多
Purpose Integrated positron emission tomography and magnetic resonance(PET/MR)is a multimodality imaging technology integrating PET and MR,which can reflect the anatomical structure and physiological function simultan...Purpose Integrated positron emission tomography and magnetic resonance(PET/MR)is a multimodality imaging technology integrating PET and MR,which can reflect the anatomical structure and physiological function simultaneously.With the development of this technology,PET/MR plays an increasingly important role in clinical diagnosis and treatment.This review would demonstrate the current state of the latest advancement of PET/MR detection technology.Methods In this review,some studies of PET/MR detection technology in motion artifact correction,time of flight,noise reduction,performance testing methods,and phantoms were summarized.Results and conclusions PET/MR is advancing rapidly in imaging technology and has achieved phased achievements.The performance testing results of different models prove that the integration of PET and MR does not affect the respective performance,and the performance testing phantom for PET/MR needs further development.展开更多
Functional magnetic resonance imaging(fMRI)is one of the most commonly used methods in cognitive neuroscience on humans.In recent decades,fMRI has also been used in the awake monkey experiments to localize functiona...Functional magnetic resonance imaging(fMRI)is one of the most commonly used methods in cognitive neuroscience on humans.In recent decades,fMRI has also been used in the awake monkey experiments to localize functional brain areas and to compare the functional differences between human and monkey brains.Several procedures and paradigms have been developed to maintain proper head fixation and to perform motion control training.In this study,we extended the application of fMRI to awake cats without training,receiving a flickering checkerboard visual stimulus projected to a screen in front of them in a block-design paradigm.We found that body movement-induced non-rigid motion introduced artifacts into the functional scans,especially those around the eye and neck.To correct for these artifacts,we developed two methods:one for general experimental design,and the other for studies of whether a checkerboard task could be used as a localizer to optimize the motioncorrection parameters.The results demonstrated that,with proper animal fixation and motion correction procedures,it is possible to perform fMRI experiments with untrained awake cats.展开更多
基金the National Natural Science Foundation of China(No.82160347)Yunnan Provincial Science and Technology Department(No.202102AE090031)Yunnan Key Laboratory of Smart City in Cyberspace Security(No.202105AG070010).
文摘In addressing the challenge of motion artifacts in Positron Emission Tomography (PET) lung scans, our studyintroduces the Triple Equivariant Motion Transformer (TEMT), an innovative, unsupervised, deep-learningbasedframework for efficient respiratory motion correction in PET imaging. Unlike traditional techniques,which segment PET data into bins throughout a respiratory cycle and often face issues such as inefficiency andoveremphasis on certain artifacts, TEMT employs Convolutional Neural Networks (CNNs) for effective featureextraction and motion decomposition.TEMT’s unique approach involves transforming motion sequences into Liegroup domains to highlight fundamental motion patterns, coupled with employing competitive weighting forprecise target deformation field generation. Our empirical evaluations confirm TEMT’s superior performancein handling diverse PET lung datasets compared to existing image registration networks. Experimental resultsdemonstrate that TEMT achieved Dice indices of 91.40%, 85.41%, 79.78%, and 72.16% on simulated geometricphantom data, lung voxel phantom data, cardiopulmonary voxel phantom data, and clinical data, respectively. Tofacilitate further research and practical application, the TEMT framework, along with its implementation detailsand part of the simulation data, is made publicly accessible at https://github.com/yehaowei/temt.
文摘Objective To observe the clinical application value of total free-breathing cardiac MR(CMR)examination preliminarily.Methods Two patients who underwent CMR scanning under free-breathing state,including cine,motion correction T1 and T2 mapping,blood flow imaging,and late gadolinium enhancement scanning were retrospectively enrolled,and the qualities of the above images were evaluated and compared with that of conventional CMR images under breath-holding state.Results No significant difference of imaging quality was found between total free-breathing and conventional breath-holding CMR.The differences of left ventricular ejection fraction,cardiac output,left ventricular end-diastolic volume index and left ventricular mass measured based on CMR images under different breath conditions were limited.Conclusion Total free-breathing CMR was feasible in clinical practice,which could provide"one-stop"evaluation of cardiac structure,function and myocardial histological characteristics,hence having promising clinical prospects.
基金The National Basic Research Program of China under contract No. 2011CB403501the Fund for Creative Research Groups by NSFC of China under contract No. 40821004+1 种基金the Knowledge Innovation Programs of the Chinese Academy of Sciences under contract No. KZCX2-YW-Q07-02the High-Tech Research and Development Program (863 Program) of China under contract No. 2006AA09A309
文摘A flux system deployed on a moored buoy has been described, which is capable of directly estimating the airsea fluxes after removing the contamination in the signal due to buoy motion. A triple loop fitting method has been demonstrated for determining the three angular offsets between measurement axes of the sonic anemometer and motion pack. The data collected in an experiment in the Northern Huanghai Sea is used to correct the three sonic anemometer measurements of turbulent wind for buoy motion. The effective removal of wave-scale motion from the spectra and cospectra are demonstrated. Estimates of along-wind momentum flux, sensible heat flux and latent heat flux calculated by the eddy correlation method based on data obtained by sonic anemometer 81000V are shown to be in the same trend and scale with those determined by the bulk aerodynamic method after motion correction. The motion correction not only greatly improve the estimation of the momentum flux but also has a great impact on the calculated sensible heat flux.
基金This work was sponsored by National Natural Science Foundation of China,Nos.81571722,61775028 and 61528401.
文摘In this study,we propose a deep-learning-based method to correct motion artifacts in optical resolution photoacoustic microscopy(OR-PAM).The method is a convolutional neural network that establishes an end-to-end map from input raw data with motion artifacts to output corrected images.First,we performed simulation studies to evaluate the feasibility and effectiveness of the proposed method.Second,we employed this method to process images of rat brain vessels with multiple motion artifacts to evaluate its performance for in vivo applications.The results demonstrate that this method works well for both large blood vessels and capillary networks.In comparison with traditional methods,the proposed method in this study can be easily modified to satisfy different scenarios of motion corrections in OR-PAM by revising the training sets.
基金The National Basic Research Program of China under contract No. 2011CB403501the Public Science and Technology Research Funds Projects of Ocean of the State oceanic Administration of China under contract No. 200905012-9+1 种基金the Fund for Creative Research Groups by the National Natural Science Foundation of China under contract No. 41121064the Open Research Foundation for the key Laboratory of Ocean Circulation and Waves.Institute of Oceanology,Chinese Academy of Sciences of China under contract No.KLOCAW1207
文摘Precise measurements of the CO2 gas transfer across the air-sea interface provide a better under- standing of the global carbon cycle. The air-sea CO2 fluxes are obtained by the eddy covariance method and the bulk method from a buoy observation in the northern Huanghai sea. The effects of buoy motion on flux calculated by the eddy covariance method are demonstrated. The research shows that a motion correction can improve the correlation coefficient between the C02 fluxes esti- mated from two different levels. Without the CO2-H20 cross-correlation correction which is termed as PKT correction, the air-sea CO2 fluxes estimated by eddy covariance method using the motion corrected data are nearly an order of magnitude larger than those estimated by the bulk method. After the CO2-H20 cross-correlation correction, some eddy covariance CO2 fluxes indeed become closer to the bulk CO2 flux, whereas some are overcorrected which are in response to small water vapor flux.
基金Supported by National Natural Science Foundation of China (81101070)
文摘Respiratory motion is a major factor that affects the quality of PET images of the thoracic area. The diaphragm moves about 15–20 mm due to respiratory motion, which substantially degrades the effective spatial resolution of PET. In this paper, a gated acquisition method is used to correct the motion effects. In this method, an improved demons algorithm is proposed to align the gated images. The experimental results show that the quality of PET images is significantly improved when using our improved method and the proposed method has a faster convergence rate than the original demons algorithm.
基金the State task for IAP RAS(project No.0035-2019-0013)in part of method development by the Russian scientific foundation(project No.17-15-01507)in part of model experiments and setup creatingthe Russian Federal target program(project 14.610.21.0014 unique No.RFMEFI61017X0014)in part of retinal imaging experiments.
文摘A numerical method that compensates image distortions caused by random fluctuations of the distance to an object in spectral-domain optical coherence tomography(SD OCT)has been proposed and verified experimentally.The proposed method is based on the analysis of the phase shifts between adjacent scans that are caused by micrometer-scale displacements and the subsequent compensation for the displacements through phase-frequency correction in the spectral space.The efficiency of the method is demonstrated in model experiments with harmonic and random movements of a scattering object as well as during in vivo imaging of the retina of the human eye.
基金supported by the National Key Research and Development Program of China(No.2016YFC0500103)the Youth Innovation Promotion Association CAS(No.2017155)the Scientific Instrument Development Project from Capital Science and Technology Condition Platform(No.Z171100002817002)
文摘This Letter proposes a coordinate difference homogenization matching method to solve motion influence in three-dimensional(3D) range-intensity correlation laser imaging. Firstly, features and feature pairs of gate images are obtained by speeded-up robust figures and bi-directional feature matching methods. The original mean value of the feature-pair coordinate differences is calculated. Comparing the coordinate differences with the original mean value, the wrong feature pairs are removed, and then an optimized mean value is updated. The final feature-pair coordinates are re-registered based on the updated mean value. Thus, an accurate transformation is established to rectify motion gate images for 3D reconstruction. In the experiment, a 3D image of a tower at 780 m is successfully captured by our laser gated imaging system on a pan-tilt device.
文摘Purpose Integrated positron emission tomography and magnetic resonance(PET/MR)is a multimodality imaging technology integrating PET and MR,which can reflect the anatomical structure and physiological function simultaneously.With the development of this technology,PET/MR plays an increasingly important role in clinical diagnosis and treatment.This review would demonstrate the current state of the latest advancement of PET/MR detection technology.Methods In this review,some studies of PET/MR detection technology in motion artifact correction,time of flight,noise reduction,performance testing methods,and phantoms were summarized.Results and conclusions PET/MR is advancing rapidly in imaging technology and has achieved phased achievements.The performance testing results of different models prove that the integration of PET and MR does not affect the respective performance,and the performance testing phantom for PET/MR needs further development.
基金supported by grants from the Ministry of Science and Technology of China (2012CB825500, 2012IM030100, 2010IM030800)the National Natural Science Foundation of China (91132302, 90820307)
文摘Functional magnetic resonance imaging(fMRI)is one of the most commonly used methods in cognitive neuroscience on humans.In recent decades,fMRI has also been used in the awake monkey experiments to localize functional brain areas and to compare the functional differences between human and monkey brains.Several procedures and paradigms have been developed to maintain proper head fixation and to perform motion control training.In this study,we extended the application of fMRI to awake cats without training,receiving a flickering checkerboard visual stimulus projected to a screen in front of them in a block-design paradigm.We found that body movement-induced non-rigid motion introduced artifacts into the functional scans,especially those around the eye and neck.To correct for these artifacts,we developed two methods:one for general experimental design,and the other for studies of whether a checkerboard task could be used as a localizer to optimize the motioncorrection parameters.The results demonstrated that,with proper animal fixation and motion correction procedures,it is possible to perform fMRI experiments with untrained awake cats.