Insular lesions remain surgically challenging because of the need to balance aggressive resection and functional protection. Motor function deficits due to corticospinal tract injury are a common complication of surge...Insular lesions remain surgically challenging because of the need to balance aggressive resection and functional protection. Motor function deficits due to corticospinal tract injury are a common complication of surgery for lesions adjacent to the internal capsule and it is therefore essential to evaluate the corticospinal tract adjacent to the lesion. We used diffusion tensor imaging to evaluate the corticospinal tract in 89 patients with insular lobe lesions who underwent surgery in Chinese PLA General Hospital from February 2009 to May 2011. Postoperative motor function evaluation revealed that 57 patients had no changes in motor function, and 32 patients suffered motor dysfunction or aggravated motor dysfunction. Of the affected patients, 20 recovered motor function during the 6-12-month follow-up, and an additional 12 patients did not recover over more than 12 months of follow-up. Following reconstruction of the corticospinal tract, fractional anisotropy comparison demonstrated that preoperative, intraoperative and follow-up normalized fractional anisotropy in the stable group was higher than in the transient deficits group or the long-term deficits group. Compared with the transient deficits group, intraoperative normalized fractional anisotropy significantly decreased in the long-term deficits group. We conclude that intraoperative fractional anisotropy values of the corticospinal tracts can be used as a prognostic indicator of motor function outcome.展开更多
Abstract-The development of asynchronous brain-computer interface （BCI） based on motor imagery （M1） poses the research in algorithms for detecting the nontask states （i.e., idle state） and the design of continuo...Abstract-The development of asynchronous brain-computer interface （BCI） based on motor imagery （M1） poses the research in algorithms for detecting the nontask states （i.e., idle state） and the design of continuous classifiers that classify continuously incoming electroencephalogram （EEG） samples. An algorithm is proposed in this paper which integrates two two-class classifiers to detect idle state and utilizes a sliding window to achieve continuous outputs. The common spatial pattern （CSP） algorithm is used to extract features of EEG signals and the linear support vector machine （SVM） is utilized to serve as classifier. The algorithm is applied on dataset IVb of BCI competition Ⅲ, with a resulting mean square error of 0.66. The result indicates that the proposed algorithm is feasible in the first step of the development of asynchronous systems.展开更多
基金supported by the National Natural Science Foundation of China, No. 30800349the Natural Science Foundation of Beijing, No. 7102145
文摘Insular lesions remain surgically challenging because of the need to balance aggressive resection and functional protection. Motor function deficits due to corticospinal tract injury are a common complication of surgery for lesions adjacent to the internal capsule and it is therefore essential to evaluate the corticospinal tract adjacent to the lesion. We used diffusion tensor imaging to evaluate the corticospinal tract in 89 patients with insular lobe lesions who underwent surgery in Chinese PLA General Hospital from February 2009 to May 2011. Postoperative motor function evaluation revealed that 57 patients had no changes in motor function, and 32 patients suffered motor dysfunction or aggravated motor dysfunction. Of the affected patients, 20 recovered motor function during the 6-12-month follow-up, and an additional 12 patients did not recover over more than 12 months of follow-up. Following reconstruction of the corticospinal tract, fractional anisotropy comparison demonstrated that preoperative, intraoperative and follow-up normalized fractional anisotropy in the stable group was higher than in the transient deficits group or the long-term deficits group. Compared with the transient deficits group, intraoperative normalized fractional anisotropy significantly decreased in the long-term deficits group. We conclude that intraoperative fractional anisotropy values of the corticospinal tracts can be used as a prognostic indicator of motor function outcome.
基金supported by the National Natural Science Foundation of China under Grant No. 30525030, 60736029, 60701015, and 30870655.
文摘Abstract-The development of asynchronous brain-computer interface （BCI） based on motor imagery （M1） poses the research in algorithms for detecting the nontask states （i.e., idle state） and the design of continuous classifiers that classify continuously incoming electroencephalogram （EEG） samples. An algorithm is proposed in this paper which integrates two two-class classifiers to detect idle state and utilizes a sliding window to achieve continuous outputs. The common spatial pattern （CSP） algorithm is used to extract features of EEG signals and the linear support vector machine （SVM） is utilized to serve as classifier. The algorithm is applied on dataset IVb of BCI competition Ⅲ, with a resulting mean square error of 0.66. The result indicates that the proposed algorithm is feasible in the first step of the development of asynchronous systems.
