BACKGROUND Mucinous cystic neoplasm(MCN)of the pancreas is characterized by mucinproducing columnar epithelium and dense ovarian-type stroma and at risk for malignant transformation.Early diagnosis and treatment of MC...BACKGROUND Mucinous cystic neoplasm(MCN)of the pancreas is characterized by mucinproducing columnar epithelium and dense ovarian-type stroma and at risk for malignant transformation.Early diagnosis and treatment of MCN are particularly important.AIM To investigate the clinical characteristics of and management strategies for pancreatic mucinous cystadenoma(MCA)and mucinous cystadenocarcinoma(MCC).METHODS The clinical and pathological data of 82 patients with pancreatic MCA and MCC who underwent surgical resection at our department between April 2015 and March 2019 were retrospectively analyzed.RESULTS Of the 82 patients included in this study,70 had MCA and 12 had MCC.Tumor size of MCC was larger than that of MCA(P=0.049).Age and serum levels of tumor markers carcinoembryonic antigen(CEA),carbohydrate antigen(CA)19-9,and CA12-5 were significantly higher in MCC than in MCA patients(P=0.005,0.026,and 0.037,respectively).MCA tumor size was positively correlated with serum CA19-9 levels(r=0.389,P=0.001).Compared with MCC,MCA had a higher minimally invasive surgery rate(P=0.014).In the MCA group,the rate of major complications was 5.7%and that of clinically relevant pancreatic fistula was 8.6%;the corresponding rates in the MCC group were 16.7%and 16.7%,respectively.CONCLUSION Tumor size,age,and serum CEA,CA19-9,and CA12-5 levels may contribute to management of patients with MCN.Surgical resection is the primary treatment modality for MCC and MCA.展开更多
Goblet cell carcinoid is an uncommon primary tumor of the vermiform appendix, characterized by dual endocrine and glandular differentiation. Whether goblet cell carcinoid represents a morphological variant of appendic...Goblet cell carcinoid is an uncommon primary tumor of the vermiform appendix, characterized by dual endocrine and glandular differentiation. Whether goblet cell carcinoid represents a morphological variant of appendiceal classical carcinoid or a mucin-producing adenocarcinoma is a matter of conjecture. Rare cases of goblet cell carcinoid with other concomitant appendiceal epithelial neoplasms have been documented. In this report, we describe a rare case of combined appendiceal goblet cell carcinoid and mucinous cystadenoma, and discuss the possible histopathogenesis of this combination.展开更多
Primary retroperitoneal mucinous cystadenomas (RMCs) are very rare and their biological behavior and histogenesis remain speculative. An accurate preoperative diagnosis of these tumors is difficult because no effectiv...Primary retroperitoneal mucinous cystadenomas (RMCs) are very rare and their biological behavior and histogenesis remain speculative. An accurate preoperative diagnosis of these tumors is difficult because no effective diagnostic measures have been established. We describe a 29-year-old woman with abdominal pain and a palpable mass. Computed tomography (CT) of the abdomen revealed a retroperi-toneal cystic mass which was resected successfully at laparotomy. Histopathological examination of the resected mass confirmed the diagnosis of RMC. There was no evidence of disease 2 years after surgery.展开更多
BACKGROUND Co-occurrence of different tumor types in a same patient’s ovaries diagnosed with endometriosis is a rare phenomenon.CASE SUMMARY In this article we present an uncommon association of three distinct ovaria...BACKGROUND Co-occurrence of different tumor types in a same patient’s ovaries diagnosed with endometriosis is a rare phenomenon.CASE SUMMARY In this article we present an uncommon association of three distinct ovarian pathologies in a same woman presenting with adnexal mass.A 31-year-old nulliparous woman with a large persistent adnexal mass underwent laparoscopic surgery.Imaging demonstrated a multi-cystic mass with internal echoes.Tumor markers were within normal range.Based on histopathologic assessment,benign mucinous cystadenoma and mature cystic teratoma of the right ovary together with endometrioma of left ovary were revealed.CONCLUSION In cases of large adnexal mass,the of existence of more than one tumor type and the involvement of the contralateral ovary is possible.Also,the possibility of concurrent underlying malignancy or diminished ovarian reserve should be kept in mind.展开更多
Appendiceal mucinous cystadenoma （AMC） is an ,uncommon disease. The clinical symptoms arenon-specific, thus the preoperative diagnosis is very difficult. The importance of recognizing this condition lies in preventi...Appendiceal mucinous cystadenoma （AMC） is an ,uncommon disease. The clinical symptoms arenon-specific, thus the preoperative diagnosis is very difficult. The importance of recognizing this condition lies in preventing spillage during surgery. At present, the widespread use of computed tomography （CT） for evaluating abdominal disease has increased the detection rate and diagnostic accuracy for AMC. Here, we report the CT appearance of 4 histologically proven AMCs.展开更多
Hepatobiliary cystadenomas are rare tumors that are difficult to diagnose preoperatively. They can reach large sizes that make them real intraoperative ＂surprises＂. A 63-year-old woman, presented with a symptomatic ...Hepatobiliary cystadenomas are rare tumors that are difficult to diagnose preoperatively. They can reach large sizes that make them real intraoperative ＂surprises＂. A 63-year-old woman, presented with a symptomatic huge abdominal cystic mass, underwent complete resection of the mass with safety margins. Histopathological report revealed mucinous hepatic cystadenoma with ＂ovarian- like＂ stroma and areas of sclerohyalinization. The differential diagnosis of the large cystic tumors which occupy the right hemiabdomen must include the biliary cystadenoma; the complete resection of the tumor with safety margins avoids local recurrence, and therefore represents the optimal therapy because of the malignant potential of the disease. The postoperative follow-up includes abdominal ultrasound or CT scan and CA 19-9 measurement.展开更多
Mucinous cystadenoma of appendix is a rare clinical entity with very few reported cases in the literature.Consensus on optimal surgical management has not been reached.We report the case of a 65-year-old female patien...Mucinous cystadenoma of appendix is a rare clinical entity with very few reported cases in the literature.Consensus on optimal surgical management has not been reached.We report the case of a 65-year-old female patient who presented with fistula over the right iliac fossa.Computed tomography(CT)of the abdomen suggested abscess of the parietal wall.Upon exploration,a mass was found to be arising from the tip of the retroperitoneal appendix and the retroperitoneum was studded with mucoid material.Appendectomy was carried out and final histopathology revealed mucinous cystadenoma with no evidence of malignancy.The patient was discharged uneventfully.The unusual presentation of this disease,as retroperitoneal psuedomyxoma without any intraperitoneal pathology,prompted us to report this case.展开更多
Mucinous cystadenoma is a rare benign tumor. Because it has no specific clinical manifestations or imaging features, preoperative clinical and radiologic diagnoses are difficult to make.l-3 We report here a case of pr...Mucinous cystadenoma is a rare benign tumor. Because it has no specific clinical manifestations or imaging features, preoperative clinical and radiologic diagnoses are difficult to make.l-3 We report here a case of primary mucinous cystadenoma of the terminal ileum wall. In this report, the characteristics of the disease will be discussed and the previous reports in literature on mucinous cystadenoma in other organs will be reviewed.展开更多
Adnexal torsion is defined by the existence of a partial or complete torsion of the ovary and a tubal portion around its vascular pedicle. It is a rare gynecological emergency. We report the case of adnexal torsion on...Adnexal torsion is defined by the existence of a partial or complete torsion of the ovary and a tubal portion around its vascular pedicle. It is a rare gynecological emergency. We report the case of adnexal torsion on a large postpartum ovarian cyst in a 40-year-old patient. The diagnosis was suspected based on clinical and ultrasound signs and confirmed by exploratory laparotomy. The appearance of the cyst was suggestive of a mucinous cystadenoma of the ovary. The treatment was radical by performing an adnexectomy. The surgical piece weighed 5.2 kg. The postoperative course was simple. Anatomopathological examination had not been carried out;the parents had buried the operating piece.展开更多
Gastric duplication is a congenital malformation occurring mostly in infants or childhood. It is rarely found in adults. Some are completely separate cystic lesions unconnected to the stomach, which makes them more di...Gastric duplication is a congenital malformation occurring mostly in infants or childhood. It is rarely found in adults. Some are completely separate cystic lesions unconnected to the stomach, which makes them more difficult to diagnose in a clinical setting. Differential diagnoses of this separate form often include a pancreatic pseudocyst or pancreatic cystic tumor according to the anatomic location. Some associated anomalies have been documented in the literature, but these are rare. Herein, we report a case of gastric duplication at the splenic hilum of a young female adult with a clinical impression of endometriosis due to the coexistence of a fight ovarian cyst and image findings.展开更多
文摘BACKGROUND Mucinous cystic neoplasm(MCN)of the pancreas is characterized by mucinproducing columnar epithelium and dense ovarian-type stroma and at risk for malignant transformation.Early diagnosis and treatment of MCN are particularly important.AIM To investigate the clinical characteristics of and management strategies for pancreatic mucinous cystadenoma(MCA)and mucinous cystadenocarcinoma(MCC).METHODS The clinical and pathological data of 82 patients with pancreatic MCA and MCC who underwent surgical resection at our department between April 2015 and March 2019 were retrospectively analyzed.RESULTS Of the 82 patients included in this study,70 had MCA and 12 had MCC.Tumor size of MCC was larger than that of MCA(P=0.049).Age and serum levels of tumor markers carcinoembryonic antigen(CEA),carbohydrate antigen(CA)19-9,and CA12-5 were significantly higher in MCC than in MCA patients(P=0.005,0.026,and 0.037,respectively).MCA tumor size was positively correlated with serum CA19-9 levels(r=0.389,P=0.001).Compared with MCC,MCA had a higher minimally invasive surgery rate(P=0.014).In the MCA group,the rate of major complications was 5.7%and that of clinically relevant pancreatic fistula was 8.6%;the corresponding rates in the MCC group were 16.7%and 16.7%,respectively.CONCLUSION Tumor size,age,and serum CEA,CA19-9,and CA12-5 levels may contribute to management of patients with MCN.Surgical resection is the primary treatment modality for MCC and MCA.
文摘Goblet cell carcinoid is an uncommon primary tumor of the vermiform appendix, characterized by dual endocrine and glandular differentiation. Whether goblet cell carcinoid represents a morphological variant of appendiceal classical carcinoid or a mucin-producing adenocarcinoma is a matter of conjecture. Rare cases of goblet cell carcinoid with other concomitant appendiceal epithelial neoplasms have been documented. In this report, we describe a rare case of combined appendiceal goblet cell carcinoid and mucinous cystadenoma, and discuss the possible histopathogenesis of this combination.
文摘Primary retroperitoneal mucinous cystadenomas (RMCs) are very rare and their biological behavior and histogenesis remain speculative. An accurate preoperative diagnosis of these tumors is difficult because no effective diagnostic measures have been established. We describe a 29-year-old woman with abdominal pain and a palpable mass. Computed tomography (CT) of the abdomen revealed a retroperi-toneal cystic mass which was resected successfully at laparotomy. Histopathological examination of the resected mass confirmed the diagnosis of RMC. There was no evidence of disease 2 years after surgery.
文摘BACKGROUND Co-occurrence of different tumor types in a same patient’s ovaries diagnosed with endometriosis is a rare phenomenon.CASE SUMMARY In this article we present an uncommon association of three distinct ovarian pathologies in a same woman presenting with adnexal mass.A 31-year-old nulliparous woman with a large persistent adnexal mass underwent laparoscopic surgery.Imaging demonstrated a multi-cystic mass with internal echoes.Tumor markers were within normal range.Based on histopathologic assessment,benign mucinous cystadenoma and mature cystic teratoma of the right ovary together with endometrioma of left ovary were revealed.CONCLUSION In cases of large adnexal mass,the of existence of more than one tumor type and the involvement of the contralateral ovary is possible.Also,the possibility of concurrent underlying malignancy or diminished ovarian reserve should be kept in mind.
文摘Appendiceal mucinous cystadenoma （AMC） is an ,uncommon disease. The clinical symptoms arenon-specific, thus the preoperative diagnosis is very difficult. The importance of recognizing this condition lies in preventing spillage during surgery. At present, the widespread use of computed tomography （CT） for evaluating abdominal disease has increased the detection rate and diagnostic accuracy for AMC. Here, we report the CT appearance of 4 histologically proven AMCs.
文摘Hepatobiliary cystadenomas are rare tumors that are difficult to diagnose preoperatively. They can reach large sizes that make them real intraoperative ＂surprises＂. A 63-year-old woman, presented with a symptomatic huge abdominal cystic mass, underwent complete resection of the mass with safety margins. Histopathological report revealed mucinous hepatic cystadenoma with ＂ovarian- like＂ stroma and areas of sclerohyalinization. The differential diagnosis of the large cystic tumors which occupy the right hemiabdomen must include the biliary cystadenoma; the complete resection of the tumor with safety margins avoids local recurrence, and therefore represents the optimal therapy because of the malignant potential of the disease. The postoperative follow-up includes abdominal ultrasound or CT scan and CA 19-9 measurement.
文摘Mucinous cystadenoma of appendix is a rare clinical entity with very few reported cases in the literature.Consensus on optimal surgical management has not been reached.We report the case of a 65-year-old female patient who presented with fistula over the right iliac fossa.Computed tomography(CT)of the abdomen suggested abscess of the parietal wall.Upon exploration,a mass was found to be arising from the tip of the retroperitoneal appendix and the retroperitoneum was studded with mucoid material.Appendectomy was carried out and final histopathology revealed mucinous cystadenoma with no evidence of malignancy.The patient was discharged uneventfully.The unusual presentation of this disease,as retroperitoneal psuedomyxoma without any intraperitoneal pathology,prompted us to report this case.
文摘Mucinous cystadenoma is a rare benign tumor. Because it has no specific clinical manifestations or imaging features, preoperative clinical and radiologic diagnoses are difficult to make.l-3 We report here a case of primary mucinous cystadenoma of the terminal ileum wall. In this report, the characteristics of the disease will be discussed and the previous reports in literature on mucinous cystadenoma in other organs will be reviewed.
文摘Adnexal torsion is defined by the existence of a partial or complete torsion of the ovary and a tubal portion around its vascular pedicle. It is a rare gynecological emergency. We report the case of adnexal torsion on a large postpartum ovarian cyst in a 40-year-old patient. The diagnosis was suspected based on clinical and ultrasound signs and confirmed by exploratory laparotomy. The appearance of the cyst was suggestive of a mucinous cystadenoma of the ovary. The treatment was radical by performing an adnexectomy. The surgical piece weighed 5.2 kg. The postoperative course was simple. Anatomopathological examination had not been carried out;the parents had buried the operating piece.
文摘Gastric duplication is a congenital malformation occurring mostly in infants or childhood. It is rarely found in adults. Some are completely separate cystic lesions unconnected to the stomach, which makes them more difficult to diagnose in a clinical setting. Differential diagnoses of this separate form often include a pancreatic pseudocyst or pancreatic cystic tumor according to the anatomic location. Some associated anomalies have been documented in the literature, but these are rare. Herein, we report a case of gastric duplication at the splenic hilum of a young female adult with a clinical impression of endometriosis due to the coexistence of a fight ovarian cyst and image findings.
