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基于Group-Res2Block的智能合成语音说话人确认方法
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作者 李菲 苏兆品 +2 位作者 王年松 杨波 张国富 《应用科学学报》 CAS CSCD 北大核心 2024年第4期709-722,共14页
针对现有说话人确认任务基于自然语音条件下并不适用于智能合成语音的问题,提出一种基于Group-Res2Block的智能合成语音说话人确认方法。首先,设计了Group-Res2Block结构,在Res2Block的基础上将当前分组与相邻前后分组进行合并形成新的... 针对现有说话人确认任务基于自然语音条件下并不适用于智能合成语音的问题,提出一种基于Group-Res2Block的智能合成语音说话人确认方法。首先,设计了Group-Res2Block结构,在Res2Block的基础上将当前分组与相邻前后分组进行合并形成新的分组,以增强说话人局部特征的上下文联系;其次,设计了并行结构的多尺度通道注意力特征融合机制,利用不同大小卷积核实现同一层级的特征在通道维度的特征选择,以获取更具表现力的说话人特征,避免信息冗余;最后,设计了串行结构的多尺度层注意力特征融合机制,构建层结构,将深浅层特征整体进行融合并赋予不同权重,以获取最优的特征表达。为验证所提出特征提取网络的有效性,构建了中英文两种智能合成语音数据集进行消融实验和对比实验。结果表明本文方法在该任务的评价指标精确度(accuracy,ACC)、等错误率(equal error rate,EER)和最小检测代价函数(minimum detection cost function,minDCF)上是最优的。此外,通过对模型泛化性能进行测试,验证了本文方法对未知智能语音算法的适用性。 展开更多
关键词 说话人确认 智能合成语音 group-Res2Block深度神经网络 多尺度特征 注意力机制
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Grid Side Distributed Energy Storage Cloud Group End Region Hierarchical Time-Sharing Configuration Algorithm Based onMulti-Scale and Multi Feature Convolution Neural Network
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作者 Wen Long Bin Zhu +3 位作者 Huaizheng Li Yan Zhu Zhiqiang Chen Gang Cheng 《Energy Engineering》 EI 2023年第5期1253-1269,共17页
There is instability in the distributed energy storage cloud group end region on the power grid side.In order to avoid large-scale fluctuating charging and discharging in the power grid environment and make the capaci... There is instability in the distributed energy storage cloud group end region on the power grid side.In order to avoid large-scale fluctuating charging and discharging in the power grid environment and make the capacitor components showa continuous and stable charging and discharging state,a hierarchical time-sharing configuration algorithm of distributed energy storage cloud group end region on the power grid side based on multi-scale and multi feature convolution neural network is proposed.Firstly,a voltage stability analysis model based onmulti-scale and multi feature convolution neural network is constructed,and the multi-scale and multi feature convolution neural network is optimized based on Self-OrganizingMaps(SOM)algorithm to analyze the voltage stability of the cloud group end region of distributed energy storage on the grid side under the framework of credibility.According to the optimal scheduling objectives and network size,the distributed robust optimal configuration control model is solved under the framework of coordinated optimal scheduling at multiple time scales;Finally,the time series characteristics of regional power grid load and distributed generation are analyzed.According to the regional hierarchical time-sharing configuration model of“cloud”,“group”and“end”layer,the grid side distributed energy storage cloud group end regional hierarchical time-sharing configuration algorithm is realized.The experimental results show that after applying this algorithm,the best grid side distributed energy storage configuration scheme can be determined,and the stability of grid side distributed energy storage cloud group end region layered timesharing configuration can be improved. 展开更多
关键词 multiscale and multi feature convolution neural network distributed energy storage at grid side cloud group end region layered time-sharing configuration algorithm
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Multi-Criteria Group Decision-Making Method Based on an Improved Single-Valued Neutrosophic Hamacher Weighted Average Operator and Grey Relational Analysis
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作者 Ye Mei Junjie Yang Bo Chen 《Journal of Computer and Communications》 2023年第3期167-188,共22页
This paper proposes a multi-criteria decision-making (MCGDM) method based on the improved single-valued neutrosophic Hamacher weighted averaging (ISNHWA) operator and grey relational analysis (GRA) to overcome the lim... This paper proposes a multi-criteria decision-making (MCGDM) method based on the improved single-valued neutrosophic Hamacher weighted averaging (ISNHWA) operator and grey relational analysis (GRA) to overcome the limitations of present methods based on aggregation operators. First, the limitations of several existing single-valued neutrosophic weighted averaging aggregation operators (i.e. , the single-valued neutrosophic weighted averaging, single-valued neutrosophic weighted algebraic averaging, single-valued neutrosophic weighted Einstein averaging, single-valued neutrosophic Frank weighted averaging, and single-valued neutrosophic Hamacher weighted averaging operators), which can produce some indeterminate terms in the aggregation process, are discussed. Second, an ISNHWA operator was developed to overcome the limitations of existing operators. Third, the properties of the proposed operator, including idempotency, boundedness, monotonicity, and commutativity, were analyzed. Application examples confirmed that the ISNHWA operator and the proposed MCGDM method are rational and effective. The proposed improved ISNHWA operator and MCGDM method can overcome the indeterminate results in some special cases in existing single-valued neutrosophic weighted averaging aggregation operators and MCGDM methods. 展开更多
关键词 Single-Valued Neutrosophic Numbers Single-Valued Neutrosophic Hamacher Weighted Averaging Operator Grey Relational Analysis multi-Criteria Decision-Making multi-Criteria group Decision-Making
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基于GRA-GCRITIC和改进加权双向投影的区间Fermatean模糊多属性群决策方法
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作者 赵敬华 施佳 +1 位作者 荣海迎 林杰 《计算机应用研究》 CSCD 北大核心 2024年第2期493-500,共8页
针对司法案件决策环境的复杂性及评价信息的模糊性,提出一种基于GRA-GCRITIC(grey relational analysis-group criteria importance through intercriteria correlation)和改进加权双向投影的区间Fermatean模糊Hamacher-TODIM多属性群... 针对司法案件决策环境的复杂性及评价信息的模糊性,提出一种基于GRA-GCRITIC(grey relational analysis-group criteria importance through intercriteria correlation)和改进加权双向投影的区间Fermatean模糊Hamacher-TODIM多属性群决策方法。首先考虑到各位专家对各评价方案下各指标评价信息的差异性,提出一种GRA-GCRITIC方法,该方法将灰色关联融入到CRITIC中,以确定指标综合权重比单一获取的指标权重更加客观可靠;其次,结合信任关系对加权双向投影法进行改进,兼顾主客观关系,利用专家个体与群体评价信息的隶属度及非隶属度矩阵间的相似度得到专家权重;最后,考虑到决策者的损失规避心理,将融合了Hamacher算子的TODIM方法拓展至区间Fermatean模糊环境中,通过具体算例可得到其综合优势度及排序,验证了所提方法的可行性及灵活性。 展开更多
关键词 区间Fermatean模糊 GRA-GCRITIC 改进加权双向投影 Hamacher-TODIM 多属性群决策
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基于CMCP-LMCL的多分类深度神经网络及其应用
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作者 王小燕 冮建伟 姚欣悦 《统计研究》 北大核心 2024年第7期148-160,共13页
多分类问题涉及信用风险管理、股票走势预测等多个领域。深度神经网络(DNN)是常用于多分类预测的机器学习模型,然而输入特征维度较高且存在冗余信号时,将加重其可解释性不强和结构冗余等缺陷;同时,常用的Softmax损失也可能面临分类边界... 多分类问题涉及信用风险管理、股票走势预测等多个领域。深度神经网络(DNN)是常用于多分类预测的机器学习模型,然而输入特征维度较高且存在冗余信号时,将加重其可解释性不强和结构冗余等缺陷;同时,常用的Softmax损失也可能面临分类边界模糊导致预测效果不佳等问题。为此,本文针对多分类问题,提出一个新的深度神经网络CMCP-LMCL,利用CMCP变量选择方法压缩输入特征到第1隐藏层的权重。该方法融合权重的组结构,能够剔除无关特征以及不重要的连接;同时,对特征层之外的权重施加权重衰减L;2;惩罚,有利于改进过拟合问题。新方法的增强边缘余弦损失(LMCL)在Softmax基础上引入扩大参数和距离参数,增大分类决策边界的间隔以期提高分类预测性能。模拟分析表明,对比已有DNN和传统分类方法,无论特征以简单线性形式还是复杂非线性形式映射到因变量,本文所提出的方法均具有良好的特征选择性能和预测表现。基于信用贷款数据的实证分析表明,该方法能够有效选择风险指标并进行违约风险预警。 展开更多
关键词 组变量选择 深度神经网络 多分类 信用风险评估
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计及群体压力和群体极化的PDHFSs-TODIM多属性群体决策算法
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作者 袁畅 孙永辉 +2 位作者 王森 武云逸 周伟 《浙江大学学报(理学版)》 CAS CSCD 北大核心 2024年第4期407-417,共11页
在概率对偶犹豫模糊环境下的多属性决策中,针对决策过程一般未考虑决策专家在讨论中所受的群体压力和群体极化的问题,提出了一种计及群体压力和群体极化的概率对偶犹豫模糊集-拓扑判别目标间方法(probabilistic discriminative heteroge... 在概率对偶犹豫模糊环境下的多属性决策中,针对决策过程一般未考虑决策专家在讨论中所受的群体压力和群体极化的问题,提出了一种计及群体压力和群体极化的概率对偶犹豫模糊集-拓扑判别目标间方法(probabilistic discriminative heterogeneous fuzzy sets-topological discriminative inter-objective method,PDHFSsTODIM)的多属性群体决策算法。首先,定义了考虑群体压力的决策信息修正公式,有效削弱群体压力对专家决策信息的影响;然后,搭建了一种考虑群体极化现象的决策模型,该模型充分考虑了专家的主观性,为专家讨论和修正决策提供了机会,通过分配动态决策权重提高决策的置信度,并通过群体极化阈值约束群体的极化效应;进一步,将计算得到的决策数据输入改进的TODIM算法,得到最终决策结果。将算法运用于储能电池综合性能评估分析,通过与其他先进决策算法做对比,验证了所提算法的可靠性与准确性。 展开更多
关键词 概率对偶犹豫模糊集 多属性群体决策 群体压力
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GLOBAL STABILITY OF EXTENDED MULTI-GROUP SIR EPIDEMIC MODELS WITH PATCHES THROUGH MIGRATION AND CROSS PATCH INFECTION 被引量:7
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作者 Yoshiaki MUROYA Yoichi ENATSU Toshikazu KUNIYA 《Acta Mathematica Scientia》 SCIE CSCD 2013年第2期341-361,共21页
In this article, we establish the global stability of an endemic equilibrium of multi-group SIR epidemic models, which have not only an exchange of individuals between patches through migration but also cross patch in... In this article, we establish the global stability of an endemic equilibrium of multi-group SIR epidemic models, which have not only an exchange of individuals between patches through migration but also cross patch infection between different groups. As a result, we partially generalize the recent result in the article [16]. 展开更多
关键词 multi-group SIR epidemic model PATCH global asymptotic stability Lyapunovfunction
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A modified multi-group model of angular and momentum distribution of cosmic ray muons for thickness measurement and material discrimination of slabs 被引量:4
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作者 Sa Xiao Wei-Bo He +2 位作者 Ming-Cong Lan Ying Chen Mao-Bing Shuai 《Nuclear Science and Techniques》 SCIE CAS CSCD 2018年第2期111-117,共7页
Muon tomography is a capable imaging technique to measure the geometry of high-Z objects. However,most existed algorithms used in muon tomography have obscured the effects of angular distribution and momentum spectra ... Muon tomography is a capable imaging technique to measure the geometry of high-Z objects. However,most existed algorithms used in muon tomography have obscured the effects of angular distribution and momentum spectra of cosmic ray muons and reduced the spatial resolution. We present a modified multi-group model that takes into account these effects and calibrates the model by the material of lead. Performance tests establish that the model is capable of measuring the thickness of a Pb slab and identifying the material of an unknown slab on a reasonable exposure timescale, in both cases of complete and incomplete angular data. Results show that the modified multi-group model is helpful for improvements in image resolution in real applications. 展开更多
关键词 MUON tomography MODIFIED multi-group model ANGULAR distribution MOMENTUM spectra
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Novel combinatorial algorithm for the problems of fuzzy grey multi-attribute group decision making 被引量:13
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作者 Rao Congjun Xiao Xinping Peng Jin 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2007年第4期774-780,共7页
To study the fuzzy and grey information in the problems of multi-attribute group decision making, the basic concepts of both fuzzy grey numbers and grey interval numbers are given firstly, then a new model of fuzzy gr... To study the fuzzy and grey information in the problems of multi-attribute group decision making, the basic concepts of both fuzzy grey numbers and grey interval numbers are given firstly, then a new model of fuzzy grey multi-attribute group decision making based on the theories of fuzzy mathematics and grey system is presented. Furthermore, the grey interval relative degree and deviation degree is defined, and both the optimistic algorithm of the grey interval relational degree and the algorithm of deviation degree minimization for solving this new model are also given. Finally, a decision making example to demonstrate the feasibility and rationality of this new method is given, and the results by using these two algorithms are uniform. 展开更多
关键词 multi-attribute group decision making fuzzy grey number grey interval relational degree deviation degree
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Global dynamics of a novel multi-group model for computer worms 被引量:3
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作者 巩永旺 宋玉蓉 蒋国平 《Chinese Physics B》 SCIE EI CAS CSCD 2013年第4期56-62,共7页
In this paper, we study worm dynamics in computer networks composed of many autonomous systems. A novel multigroup SIQR (susceptible-infected-quarantined-removed) model is proposed for computer worms by explicitly c... In this paper, we study worm dynamics in computer networks composed of many autonomous systems. A novel multigroup SIQR (susceptible-infected-quarantined-removed) model is proposed for computer worms by explicitly considering anti-virus measures and the network infrastructure. Then, the basic reproduction number of worm R0 is derived and the global dynamics of the model are established. It is shown that if R0 is less than or equal to 1, the disease-free equilibrium is globally asymptotically stable and the worm dies out eventually, whereas, if R0 is greater than 1, one unique endemic equilibrium exists and it is globally asymptotically stable, thus the worm persists in the network. Finally, numerical simulations are given to illustrate the theoretical results. 展开更多
关键词 computer worm multi-group model Lyapunov function global dynamics
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Multi-group ant colony algorithm based on simulated annealing method 被引量:2
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作者 朱经纬 芮挺 +1 位作者 廖明 张金林 《Journal of Shanghai University(English Edition)》 CAS 2010年第6期464-468,共5页
To overcome the default of single search tendency, the ants in the colony are divided into several sub-groups. The ants in different subgroups have different trail information and expectation coefficients. The simulat... To overcome the default of single search tendency, the ants in the colony are divided into several sub-groups. The ants in different subgroups have different trail information and expectation coefficients. The simulated annealing method is introduced to the algorithm. Through setting the temperature changing with the iterations, after each turn of tours, the solution set obtained by the ants is taken as the candidate set. The update set is obtained by adding the solutions in the candidate set to the previous update set with the probability determined by the temperature. The solutions in the candidate set are used to update the trail information. In each turn of updating, the current best solution is also used to enhance the trail information on the current best route. The trail information is reset when the algorithm is in stagnation state. The computer experiments demonstrate that the proposed algorithm has higher stability and convergence speed. 展开更多
关键词 ant colony algorithm simulated annealing method multi-group candidate set update set
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Multi-group pin power reconstruction method based on colorset form functions 被引量:1
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作者 HUANG Hao 《Nuclear Science and Techniques》 SCIE CAS CSCD 2009年第1期60-64,共5页
A multi-group pin power reconstruction method that fully exploits nodal information obtained from global coarse mesh solution has been developed.It expands the intra-nodal flux distributions into nonseparable semi-ana... A multi-group pin power reconstruction method that fully exploits nodal information obtained from global coarse mesh solution has been developed.It expands the intra-nodal flux distributions into nonseparable semi-analytic basis functions,and a colorset based form function generating method is proposed,which can accurately model the spectral interaction occurring at assembly interface.To demonstrate its accuracy and applicability to realistic problems, the new method is tested against two benchmark problems,including a mixed-oxide fuel problem.The results show that the new method is comparable in accuracy to fine-mesh methods. 展开更多
关键词 群组管理 LWR 二维多群辐射 输运过程 原子核
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Multi-proxy quantum group signature scheme with threshold shared verification 被引量:4
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作者 杨宇光 《Chinese Physics B》 SCIE EI CAS CSCD 2008年第2期415-418,共4页
A multi-proxy quantum group signature scheme with threshold shared verification is proposed. An original signer may authorize a proxy group as his proxy agent. Then only the cooperation of all the signers in the proxy... A multi-proxy quantum group signature scheme with threshold shared verification is proposed. An original signer may authorize a proxy group as his proxy agent. Then only the cooperation of all the signers in the proxy group can generate the proxy signature on behalf of the original signer. In the scheme, any t or more of n receivers can verify the message and any t - 1 or fewer receivers cannot verify the validity of the proxy signature. 展开更多
关键词 quantum signature multi-proxy quantum group signature threshold shared verification
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基于决策者偏好构造的概率语言型Z-number多属性决策方法
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作者 王旭婷 毛军军 张新宇 《海南师范大学学报(自然科学版)》 CAS 2024年第2期135-143,共9页
由于决策环境的日益复杂,专家评价信息往往会包含专家偏好,因此有必要对专家偏好进行识别与处理。针对这一情况,提出了基于决策者偏好构造的概率语言型Z-number并应用于多属性决策问题中。首先,针对专家偏好未知的情况,提出了一种基于... 由于决策环境的日益复杂,专家评价信息往往会包含专家偏好,因此有必要对专家偏好进行识别与处理。针对这一情况,提出了基于决策者偏好构造的概率语言型Z-number并应用于多属性决策问题中。首先,针对专家偏好未知的情况,提出了一种基于修正的平均得分距离,由专家评价信息确定专家偏好。然后,依据得到的专家偏好,利用GOWPA算子与最大熵生成概率语言型Z-number。同时,获得专家评价信息的可信度,由专家可信度聚合专家信息并采用TODIM方法对方案进行排序。最后,在国家大力提倡节能减排的背景下,将所提方法应用于国家绿色矿山试点企业的选取上,验证了所提方法的有效性和可行性。 展开更多
关键词 概率语言型Z-number 偏好 GOWPA算子 最大熵 多准则群决策
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Multi-criteria group decision making with fuzzy data:an extension of the VIKOR method 被引量:2
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作者 Wenqi Jiang Jennifer Shang 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2015年第4期764-773,共10页
The VIKOR method is a multi-criteria decision making aid, which employs linear normalization to offer compromise solu- tions and has been successfully applied to various group decision making problems. However, the co... The VIKOR method is a multi-criteria decision making aid, which employs linear normalization to offer compromise solu- tions and has been successfully applied to various group decision making problems. However, the conventional VIKOR techniques used to integrate group judgments and the information loss arising from defuzzification are problematic and distort final outcomes. An improved integration method, which is optimization-based, is proposed. And it can handle fuzzy criteria values and weights. The precondition for accurately defuzzifying triangular fuzzy num- bers is identified. Several effective defuzzification procedures are proposed to improve the extant VIKOR, and a comprehensive evaluation framework is offered to aid multi-criteria group decision making. Finally, a numerical example is provided to illustrate the practicability of the proposed method. 展开更多
关键词 multi-criteria group decision making triangular fuzzynumbers VlKOR compromise solution.
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Power Aggregation Operators of Simplified Neutrosophic Sets and Their Use in Multi-attribute Group Decision Making 被引量:2
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作者 Chunfang Liu Yuesheng Luo 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2019年第2期575-583,共9页
The simplified neutrosophic set(SNS) is a useful generalization of the fuzzy set that is designed for some practical situations in which each element has different truth membership function, indeterminacy membership f... The simplified neutrosophic set(SNS) is a useful generalization of the fuzzy set that is designed for some practical situations in which each element has different truth membership function, indeterminacy membership function and falsity membership function. In this paper, we develop a series of power aggregation operators called simplified neutrosophic number power weighted averaging(SNNPWA) operator, simplified neutrosophic number power weighted geometric(SNNPWG) operator, simplified neutrosophic number power ordered weighted averaging(SNNPOWA) operator and simplified neutrosophic number power ordered weighted geometric(SNNPOWG) operator. We present some useful properties of the operators and discuss the relationships among them. Moreover, an approach to multiattribute group decision making(MAGDM) within the framework of SNSs is developed by the above aggregation operators.Finally, a practical application of the developed approach to deal with the problem of investment is given, and the result shows that our approach is reasonable and effective in dealing with uncertain decision making problems. 展开更多
关键词 multi-ATTRIBUTE group decision making(MAGDM) POWER AGGREGATION operator(PAO) simplified neutrosophic set(SNS) uncertainty
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Dynamic programming methodology for multi-criteria group decision-making under ordinal preferences 被引量:3
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作者 Wu Li Guanqi Guo +1 位作者 Chaoyuan Yue Yong Zhao 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2010年第6期975-980,共6页
A method of minimizing rankings inconsistency is proposed for a decision-making problem with rankings of alternatives given by multiple decision makers according to multiple criteria. For each criteria, at first, the ... A method of minimizing rankings inconsistency is proposed for a decision-making problem with rankings of alternatives given by multiple decision makers according to multiple criteria. For each criteria, at first, the total inconsistency between the rankings of all alternatives for the group and the ones for every decision maker is defined after the decision maker weights in respect to the criteria are considered. Similarly, the total inconsistency between their final rankings for the group and the ones under every criteria is determined after the criteria weights are taken into account. Then two nonlinear integer programming models minimizing respectively the two total inconsistencies above are developed and then transformed to two dynamic programming models to obtain separately the rankings of all alternatives for the group with respect to each criteria and their final rankings. A supplier selection case illustrated the proposed method, and some discussions on the results verified its effectiveness. This work develops a new measurement of ordinal preferences’ inconsistency in multi-criteria group decision-making (MCGDM) and extends the cook-seiford social selection function to MCGDM considering weights of criteria and decision makers and can obtain unique ranking result. 展开更多
关键词 multi-criteria group decision-making (MCGDM) ordinal preference minimum deviation method dynamic programming Cook-Seiford social selection function.
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Pythagorean Uncertain Linguistic Variable Hamy Mean Operator and Its Application to Multi-attribute Group Decision Making 被引量:2
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作者 Huidong Wang Shifan He +1 位作者 Chengdong Li Xiaohong Pan 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2019年第2期527-539,共13页
Pythagorean fuzzy set(PFS) can provide more flexibility than intuitionistic fuzzy set(IFS) for handling uncertain information, and PFS has been increasingly used in multi-attribute decision making problems. This paper... Pythagorean fuzzy set(PFS) can provide more flexibility than intuitionistic fuzzy set(IFS) for handling uncertain information, and PFS has been increasingly used in multi-attribute decision making problems. This paper proposes a new multiattribute group decision making method based on Pythagorean uncertain linguistic variable Hamy mean(PULVHM) operator and VIKOR method. Firstly, we define operation rules and a new aggregation operator of Pythagorean uncertain linguistic variable(PULV) and explore some properties of the operator.Secondly, taking the decision makers' hesitation degree into account, a new score function is defined, and we further develop a new group decision making approach integrated with VIKOR method. Finally, an investment example is demonstrated to elaborate the validity of the proposed method. Sensibility analysis and comprehensive comparisons with another two methods are performed to show the stability and advantage of our method. 展开更多
关键词 Hamy mean(HM) OPERATOR multi-ATTRIBUTE group decision making(MAGDM) PYTHAGOREAN fuzzy set PYTHAGOREAN UNCERTAIN LINGUISTIC variable
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MiR-142-3p Regulates ILC1s by Targeting HMGB1 via the NF-κB Pathway in a Mouse Model of Early Pregnancy Loss 被引量:1
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作者 Xiang-li PANG Jie LI +2 位作者 Jing WANG Si-si YAN Jing YANG 《Current Medical Science》 SCIE CAS 2024年第1期195-211,共17页
Objective Innate lymphoid cells(ILCs)are a class of newly discovered immunocytes.Group 1 ILCs(ILC1s)are identified in the decidua of humans and mice.High mobility group box 1(HMGB1)is predicted to be one of the target... Objective Innate lymphoid cells(ILCs)are a class of newly discovered immunocytes.Group 1 ILCs(ILC1s)are identified in the decidua of humans and mice.High mobility group box 1(HMGB1)is predicted to be one of the target genes of miR-142-3p,which is closely related to pregnancy-related diseases.Furthermore,miR-142-3p and HMGB1 are involved in regulating the NF-κB signaling pathway.This study aimed to examine the regulatory effect of miR-142-3p on ILC1s and the underlying mechanism involving HMGB1 and the NF-κB signaling pathway.Methods Mouse models of normal pregnancy and abortion were constructed,and the alterations of ILC1s,miR-142-3p,ILC1 transcription factor(T-bet),and pro-inflammatory cytokines of ILC1s(TNF-α,IFN-γand IL-2)were detected in mice from different groups.The targeting regulation of HMGB1 by miR-142-3p in ILC1s,and the expression of HMGB1 in normal pregnant mice and abortive mice were investigated.In addition,the regulatory effects of miR-142-3p and HMGB1 on ILC1s were detected in vitro by CCK-8,Annexin-V/PI,ELISA,and RT-PCR,respectively.Furthermore,changes of the NF-κB signaling pathway in ILC1s were examined in the different groups.For the in vivo studies,miR-142-3p-Agomir was injected in the uterus of abortive mice to evaluate the abortion rate and alterations of ILC1s at the maternal-fetal interface,and further detect the expression of HMGB1,pro-inflammatory cytokines,and the NF-κB signaling pathway.Results The number of ILC1s was significantly increased,the level of HMGB1 was significantly upregulated,and that of miR-142-3p was considerably downregulated in the abortive mice as compared with the normal pregnant mice(all P<0.05).In addition,miR-142-3p was found to drastically inhibit the activation of the NF-κB signaling pathway(P<0.05).The number of ILC1s and the levels of pro-inflammatory cytokines were significantly downregulated and the activation of the NF-κB signaling pathway was inhibited in the miR-142-3p Agomir group(all P<0.05).Conclusion miR-142-3p can regulate ILC1s by targeting HMGB1 via the NF-κB signaling pathway,and attenuate the inflammation at the maternal-fetal interface in abortive mice. 展开更多
关键词 maternal-fetal interface group 1 innate lymphoid cells(ILCis) high mobility group box 1(HMGB1) miR-142-3p ABORTION
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Group consensus of multi-agent systems subjected to cyber-attacks 被引量:1
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作者 Hai-Yun Gao Ai-Hua Hu +1 位作者 Wan-Qiang Shen Zheng-Xian Jiang 《Chinese Physics B》 SCIE EI CAS CSCD 2019年第6期91-98,共8页
In this paper, we investigate the group consensus for leaderless multi-agent systems. The group consensus protocol based on the position information from neighboring agents is designed. The network may be subjected to... In this paper, we investigate the group consensus for leaderless multi-agent systems. The group consensus protocol based on the position information from neighboring agents is designed. The network may be subjected to frequent cyberattacks, which is close to an actual case. The cyber-attacks are assumed to be recoverable. By utilizing algebraic graph theory, linear matrix inequality(LMI) and Lyapunov stability theory, the multi-agent systems can achieve group consensus under the proposed control protocol. The sufficient conditions of the group consensus for the multi-agent networks subjected to cyber-attacks are given. Furthermore, the results are extended to the consensus issue of multiple subgroups with cyber-attacks. Numerical simulations are performed to demonstrate the effectiveness of the theoretical results. 展开更多
关键词 multi-AGENT systems group CONSENSUS cyber-attacks multiple SUBgroupS
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