Bituminous materials are heat-sensitive, and their mechanical properties vary with temperature. This variation in properties is not without consequences on the performance of flexible road structures under the repeate...Bituminous materials are heat-sensitive, and their mechanical properties vary with temperature. This variation in properties is not without consequences on the performance of flexible road structures under the repeated passage of multi-axles. This study determines the influence of seasonal variations on the rate of permanent deformation, the rut depth of flexible pavements and the effect of alternating loading of heavy goods vehicles following the temperature variations on the durability of roads. Thus, an ambient and pavement surface temperature measurement was carried out in 2022. The temperature profile at different layers of the modelled pavement, the evaluation of deformation rates and rutting depth were determined using several models. The results show that the permanent deformation and rutting rates are higher at the level of the bituminous concrete layer than at the level of the asphalt gravel layer because the stresses decrease from the surface to the depth of the pavement. On the other hand, the variations in these rates, permanent deformations and ruts between the hot and so-called cold periods are more pronounced in the bitumen gravel than in bituminous concrete, showing that gravel bitumen is more sensitive to temperature variations than bituminous concrete despite its higher rigidity. Of these results, we suggested a periodic and alternating loading of the different types of heavy goods vehicles. These loads consist of fully applying the WAEMU standards with a tolerance of 15% during periods of high and low temperatures. This regulation has increased 2 to 3 times in the durability of roadways depending on the type of heavy goods vehicle.展开更多
The multiplication of heavy vehicle axles and road overloads are phenomena that are becoming increasingly important on the road network of the WAEMU community. These phenomena, although framed by standards, have an im...The multiplication of heavy vehicle axles and road overloads are phenomena that are becoming increasingly important on the road network of the WAEMU community. These phenomena, although framed by standards, have an impact on the durability of pavements. In this manuscript it is a question of evaluating the life of the road under the effect of traffic of these multi-axle vehicles and the different tolerances of overloads observed on the road network. To achieve this, a modeling of a bituminous pavement was made with the software ALIZE Lcpc Version 231 based on the principle of the French method of sizing. An inventory of multi-axle heavy goods vehicles was also made on a road with a weighing station. This traffic counting made it possible to classify heavy goods vehicles into three categories, namely: 1) trucks, 2) dual-wheeled semi-trailers and 3) single-wheeled semi-trailers. The results obtained show that in terms of aggressiveness, single-wheeled semi-trailers are the most aggressive, followed by heavy goods vehicles in the category of trucks with more than five axles and semi-trailers with dual wheels with more than seven axles. The durability of the road depends on the aggressiveness of heavy goods vehicles, it was found that the tolerance threshold for overloads of 15% of the total permissible rolling weight (TARW) or the total permissible laden weight (TALW) currently granted in the Community area needs to be reviewed. For durable road surfaces, this tolerance may only be allowed for heavy goods vehicles of type P11, P12 and P13. The 5% tolerance can be applied to all vehicles except heavy goods vehicles with single wheels.展开更多
This study explores the effects of dynamic and static loading on rock bolt performance a key factor in maintaining the structural safety of coal mine roadways susceptible to coal bursts.Employing a housemade load fram...This study explores the effects of dynamic and static loading on rock bolt performance a key factor in maintaining the structural safety of coal mine roadways susceptible to coal bursts.Employing a housemade load frame to simulate various failure scenarios,pretension-impact-pull tests on rock bolts were conducted to scrutinize their dynamic responses under varied static load conditions and their failure traits under combined loads.The experimental results denote that with increased impact energy,maximum and average impact loads on rock bolts escalate significantly under pretension,initiating plastic deformation beyond a certain threshold.Despite minor reductions in the yield load due to impactinduced damage,pretension aids in constraining post-impact deformation rate and fluctuation degree of rock bolts.Moreover,impact-induced plastic deformation causes internal microstructure dislocation,fortifying the stiffness of the rock bolt support system.The magnitude of this fortification is directly related to the plastic deformation induced by the impact.These findings provide crucial guidance for designing rock bolt support in coal mine roadway excavation,emphasizing the necessity to consider both static and dynamic loads for improved safety and efficiency.展开更多
The stability control of fissured rock is difficult,especially under static and dynamic loads in deep coal mines.In this paper,the dynamic mechanical properties,strain rate evolution and energy dissipation of fissured...The stability control of fissured rock is difficult,especially under static and dynamic loads in deep coal mines.In this paper,the dynamic mechanical properties,strain rate evolution and energy dissipation of fissured and anchored rocks were respectively obtained by SHPB tests.It was found that bolt can provide supporting efficiency-improving effect for fissured rock against dynamic disturbance,and this effect increased quadratically with decrease in anchoring angles.Then,the energy dissipation mechanism of anchored rock was obtained by slipping model.Furthermore,bolt energy-absorbing mechanism by instantaneous tensile-shear deformation was expressed based on material mechanics,which was the larger the anchoring angle,the smaller the energy absorption,and the less the contribution to supporting efficiency improvement.On this basis,the functional relationship between energy dissipation of anchored rock and energy absorption of bolt was established.Taking the coal-gangue separation system of Longgu coal mine as an example,the optimal anchoring angle can be determined as 57.5°–67.5°.Field monitoring showed fissured rock with the optimal anchoring angle,can not only effectively control the deformation,but also fully exert the energy-absorbing and efficiency-improving effect of bolt itself.This study provides guidance to the stability control and supporting design for deep engineering under the same or similar conditions.展开更多
This work presents a novel approach to the dynamic response analysis of a Euler-Bernoulli beam resting on a Winkler soil model and subjected to an impact loading.The approach considers that damping has much less impor...This work presents a novel approach to the dynamic response analysis of a Euler-Bernoulli beam resting on a Winkler soil model and subjected to an impact loading.The approach considers that damping has much less importance in controlling the maximum response to impulsive loadings because the maximum response is reached in a very short time,before the damping forces can dissipate a significant portion of the energy input into the system.The development of two sine series solutions,relating to different types of impulsive loadings,one involving a single concentrated force and the other a distributed line load,are presented.This study revealed that when a simply supported Euler-Bernoulli beam,resting on a Winkler soil model,is subject to an impact load,the resulting vertical displacements,bending moments and shear forces produced along the span of the beam are considerably affected.In particular,the quantification of this effect is best observed,relative to the corresponding static solution,via an amplification factor.The computed impact amplification factors,for the sub-grade moduli used in this study,were in magnitude greater than 2,thus confirming the multiple-degree-of-freedom nature of the problem.展开更多
The performance of geosynthetic-reinforced embankments under traffic moving loads is always a hotspot in the geotechnical engineering field.A three-dimensional(3D)model of a geosynthetic-reinforced embankment without ...The performance of geosynthetic-reinforced embankments under traffic moving loads is always a hotspot in the geotechnical engineering field.A three-dimensional(3D)model of a geosynthetic-reinforced embankment without drainage consolidation was established using the finite element software ABAQUS.In this model,the traffic loads were simulated by two moving loads of rectangular pattern,and their amplitude,range,and moving speed were realized by a Fortran subroutine.The embankment fill was simulated by an equivalent linear viscoelastic model,which can reflect its viscoelasticity.The geogrid was simulated by the truss element,and the geocell was simulated by the membrane element.Infinite elements were utilized to weaken the boundary effect caused by the model geometry at the boundaries.Validation of the established numerical model was conducted by comparing the predicted deformations in the cross-section of the geosynthetic-reinforced embankment with those from the existing literature.On this basis,the dynamic stress and strain distribution in the pavement structure layer of the geosynthetic-reinforced embankment under a moving load was also analyzed.Finally,a parametric study was conducted to examine the influences of the different types of reinforcement,overload,and the moving load velocity on the geosynthetic-reinforced embankment.展开更多
According to the established prediction model of internal solitary wave loads on FPSO in the previous work,the lumped mass model and the movement equations of finite displacement in time domain,the dynamic response mo...According to the established prediction model of internal solitary wave loads on FPSO in the previous work,the lumped mass model and the movement equations of finite displacement in time domain,the dynamic response model of interaction between internal solitary waves and FPSO with mooring lines were established.Through calculations and analysis,time histories of dynamic loads of FPSO exerted by internal solitary waves,FPSO’s motion and dynamic tension of mooring line were obtained.The effects of the horizontal pretension of mooring line,the amplitude of internal solitary wave and layer fluid depth on dynamic response behavior of FPSO were mastered.It was shown that the internal solitary waves had significant influence on FPSO,such as the large magnitude horizontal drift and a sudden tension increment.With internal solitary wave of −170 m amplitude in the ocean with upper and lower layer fluid depth ratio being 60:550,the dynamic loads reached 991.132 kN(horizontal force),18067.3 kN(vertical force)and−5042.92 kN·m(pitching moment).Maximum of FPSO’s horizontal drift was 117.56 m.Tension increment of upstream mooring line approached 401.48 kN and that of backflow mooring line was−140 kN.Moreover,the loads remained nearly constant with different pretension but increased obviously with the changing amplitude and layer fluid depth ratio.Tension increments of mooring lines also changed little with the pretension but increased rapidly when amplitude and layer fluid depth ratio increased.However,FPSO’s motion increased quickly with not only the horizontal pretension but also the amplitude of internal solitary wave and layer fluid depth ratio.展开更多
Appropriate interaction between pantograph and catenary is imperative for smooth operation of electric trains.Changing heights of overhead lines to accommodate level crossings,overbridges,and tunnels pose significant ...Appropriate interaction between pantograph and catenary is imperative for smooth operation of electric trains.Changing heights of overhead lines to accommodate level crossings,overbridges,and tunnels pose significant challenges in maintaining consistent current collection performance as the pantograph aerodynamic profile,and thus aerodynamic load changes significantly with operational height.This research aims to analyse the global flow characteristics and aerodynamic forces acting on individual components of an HSX pantograph operating in different configurations and orientations,such that the results can be combined with multibody simulations to obtain accurate dynamic insight into contact forces.Specifically,computational fluid dynamics simulations are used to investigate the pantograph component loads in a representative setting,such as that of the recessed cavity on a Class 800 train.From an aerodynamic perspective,this study indicates that the total drag force acting on non-fixed components of the pantograph is larger for the knuckle-leading orientation rather than the knuckle-trailing,although the difference between the two is found to reduce with increasing pantograph extension.Combining the aerodynamic loads acting on individual components with multibody tools allows for realistic dynamic insight into the pantograph behaviour.The results obtained show how considering aerodynamic forces enhance the realism of the models,leading to behaviour of the pantograph-catenary contact forces closely matching that seen in experimental tests.展开更多
Dynamic wheel-rail contact forces induced by a severe form of wheel tread damage have been measured by a wheel impact load detector during full-scale field tests at different vehicle speeds.Based on laser scanning,the...Dynamic wheel-rail contact forces induced by a severe form of wheel tread damage have been measured by a wheel impact load detector during full-scale field tests at different vehicle speeds.Based on laser scanning,the measured three-dimensional damage geometry is employed in simulations of dynamic vehicle-track interaction to calibrate and verify a simulation model.The relation between the magnitude of the impact load and various operational parameters,such as vehicle speed,lateral position of wheel-rail contact,track stiffness and position of impact within a sleeper bay,is investigated.The calibrated model is later employed in simulations featuring other forms of tread damage;their effects on impact load and subsequent fatigue impact on bearings,wheel webs and subsurface initiated rolling contact fatigue of the wheel tread are assessed.The results quantify the effects of wheel tread defects and are valuable in a shift towards condition-based maintenance of running gear,and for general assessment of the severity of different types of railway wheel tread damage.展开更多
To address the issues of limited demand response data,low generalization of demand response potential evaluation,and poor demand response effect,the article proposes a demand response potential feature extraction and ...To address the issues of limited demand response data,low generalization of demand response potential evaluation,and poor demand response effect,the article proposes a demand response potential feature extraction and prediction model based on data mining and a demand response potential assessment model for adjustable loads in demand response scenarios based on subjective and objective weight analysis.Firstly,based on the demand response process and demand response behavior,obtain demand response characteristics that characterize the process and behavior.Secondly,establish a feature extraction and prediction model based on data mining,including similar day clustering,time series decomposition,redundancy processing,and data prediction.The predicted values of each demand response feature on the response day are obtained.Thirdly,the predicted data of various characteristics on the response day are used as demand response potential evaluation indicators to represent different demand response scenarios and adjustable loads,and a demand response potential evaluation model based on subjective and objective weight allocation is established to calculate the demand response potential of different adjustable loads in different demand response scenarios.Finally,the effectiveness of the method proposed in the article is verified through examples,providing a reference for load aggregators to formulate demand response schemes.展开更多
BACKGROUND Lactose intolerance(LI)is commonly seen in East Asian countries.Several studies showed that lactose or milk loading has been used as a treatment for lactose malabsorption(LM)in Western countries,but there h...BACKGROUND Lactose intolerance(LI)is commonly seen in East Asian countries.Several studies showed that lactose or milk loading has been used as a treatment for lactose malabsorption(LM)in Western countries,but there have been no reports regarding this type of treatment in Japan.As lactose or milk loading requires ingestion of large amounts of lactose within a short period,this is considered to be too harsh for Japanese people because of their less habitual milk consumption(175 mL per day in average)than Western people.In this study,we demonstrated lactose tolerance acquisition in a suitable way for Japanese.AIM To examine the efficacy of lactose(cow’s milk)loading treatment in patients with LM.METHODS Individuals with abdominal symptoms induced by milk or dairy products(LI symptoms)were identified with a questionnaire.A 20 g lactose hydrogen breath test(LHBT)was carried out to confirm LM diagnosis and to evaluate co-existence of small intestinal bacterial overgrowth(SIBO).Respondents diagnosed with LM were selected as study subjects and were treated with incremental loads of cow’s milk,starting from 30 mL and increasing up to 200 mL at 4-7 d intervals.After the treatment,changes in symptoms and LM diagnostic value of 20 g LHBT were investigated.Stool samples pre-and post-treatment were examined for changes in intestinal microbiota using 16S rRNA sequencing.Informed consent was obtained prior to each stage of the study.RESULTS In 46 subjects with LI symptoms(10-68 years old,mean age 34 years old)identified with the questionnaire,35(76.1%)were diagnosed with LM by 20 g LHBT,and 6 had co-existing SIBO.The treatment with incremental cow’s milk was carried out in 32 subjects diagnosed with LM(14-68 years old,median age 38.5 years old).The mean period of the treatment was 41±8.6 d.Improvement of symptoms was observed in 29(90.6%;95%confidence interval:75.0%-98.0%)subjects.Although 20 g LHBT indicated that 10(34.5%)subjects had improved diagnostic value of LM,no change was observed in 16(55.2%)subjects.Analysis of the fecal intestinal microbiota showed a significant increase in Blautia in 7 subjects who became symptom-free after the treatment(P=0.0313).CONCLUSION LM was diagnosed in approximately 75%of the subjects who had LI.Incremental loads of cow’s milk is regarded as a useful treatment for LM without affecting everyday life.展开更多
Heterogeneous brittle geomaterials are highly susceptible to cyclic loads.They contain inherent flaws and cracks that grow under fatigue loads and lead to failure.This study presents a numerical model for analyzing fa...Heterogeneous brittle geomaterials are highly susceptible to cyclic loads.They contain inherent flaws and cracks that grow under fatigue loads and lead to failure.This study presents a numerical model for analyzing fatigue in these materials based on the two-dimensional(2D)boundary element method and linear elastic fracture mechanics.The process is formulated by coupling the displacement discontinuity method with the incorporation technique of dissimilar regions and the governing equations of fatigue.The heterogeneous media are assumed to consist of materials with different properties,and the interfaces are assumed to be completely bonded.In addition,the domains include multiple cracks exposed to constant and variable amplitude cyclic loads.The stress intensity factor is a crucial parameter in fatigue analysis,which is determined using the displacement field around crack tips.An incremental crack growth scheme is applied to calculating the fatigue life.The growth rate values are employed to estimate the length of crack extension when there are multiple cracks.The interaction between cracks is considered,which also includes the coalescence phenomenon.Finally,various structures under different cyclic loads are examined to evaluate the accuracy of this method.The results demonstrate the efficiency of the proposed approach in modeling fatigue crack growth and life estimation.The behavior of life curves for the heterogeneous domain was as expected.These curves illustrate the breakpoints caused by utilizing discrete incremental life equations.At these points,the trend of the curves changed with the material properties and fatigue characteristics of the new material around the crack tips.展开更多
Industrial production of chemical cement leads to extreme emissions of greenhouse gases.Biological or bioinspired sustainable materials for soil treatment projects can be employed instead of chemical cement to heal th...Industrial production of chemical cement leads to extreme emissions of greenhouse gases.Biological or bioinspired sustainable materials for soil treatment projects can be employed instead of chemical cement to heal the carbon cycle in the ecosystem.The enzyme-induced calcite precipitation(EICP)method is one of the novel bio-inspired technologies that can be employed in soil treatment projects to increase desired properties of soils.While the monotonic and cyclic behavior of the enzymatically treated sands has been investigated comprehensively,the strain accumulation pattern in these improved soils under cyclic traffic loads has not been evaluated yet.In this paper,confined and unconfined cyclic compression tests are applied to the enzymatically lightly cemented sands,and the effects of the different parameters on their strain accumulation pattern are investigated for the first time in the literature.This study uses two types of specimens with unconfined compression strengths(UCS)equal to 42 kPa and 266 kPa.It is shown that the treated specimens have a rate-dependent behavior where cyclic loads with low frequencies lead to more resilient and plastic strains in the specimens.The results show that by approaching the maximum applied stresses to the UCS of the specimens(by breaking more calcite bonds between sand particles),the rate dependency behavior of specimens will reduce.Investigation of the effects of the cementation level demonstrated that by increasing the amount of the precipitated calcite from 0.38%to 0.83%,accumulated plastic strains are reduced almost 95%under the same loading condition.Effects of the initial static loads,confining pressures,the number of cycles,and amplitudes of the cyclic loads are also evaluated.展开更多
Dynamic load on anchoring structures(AS)within deep roadways can result in cumulative damage and failure.This study develops an experimental device designed to test AS under triaxial loads.The device enables the inves...Dynamic load on anchoring structures(AS)within deep roadways can result in cumulative damage and failure.This study develops an experimental device designed to test AS under triaxial loads.The device enables the investigation of the mechanical response,failure mode,instability assessment criteria,and anchorage effect of AS subjected to combined cyclic dynamic-static triaxial stress paths.The results show that the peak bearing strength is positively correlated with the anchoring matrix strength,anchorage length,and edgewise compressive strength.The bearing capacity decreases significantly when the anchorage direction is severely inclined.The free face failure modes are typically transverse cracking,concave fracturing,V-shaped slipping and detachment,and spallation detachment.Besides,when the anchoring matrix strength and the anchorage length decrease while the edgewise compressive strength,loading rate,and anchorage inclination angle increase,the failure intensity rises.Instability is determined by a negative tangent modulus of the displacement-strength curve or the continued deformation increase against the general downward trend.Under cyclic loads,the driving force that breaks the rock mass along the normal vector and the rigidity of the AS are the two factors that determine roadway stability.Finally,a control measure for surrounding rock stability is proposed to reduce the internal driving force via a pressure relief method and improve the rigidity of the AS by full-length anchorage and grouting modification.展开更多
Rock bolts are extensively utilized in underground engineering as a means of offering support and stability to rock masses in tunnels,mines,and other underground structures.In environments of high ground stress,faults...Rock bolts are extensively utilized in underground engineering as a means of offering support and stability to rock masses in tunnels,mines,and other underground structures.In environments of high ground stress,faults or weak zones can frequently arise in rock formations,presenting a significant challenge for engineering and potentially leading to underground engineering collapse.Rock bolts serve as a crucial structural element for the transmission of tensile stress and are capable of withstanding shear loads to prevent sliding of weak zones within rock mass.Therefore,a complete understanding of the behavior of rock bolts subjected to shear loads is essential.This paper presents a state-of-the-art review of the research progress of rock bolts subjected to shear load in three categories:experiment,numerical simulation,and analytical model.The review focuses on the research studies and developments in this area since the 1970s,providing a comprehensive overview of numerous factors that influence the anchorage performance of rock bolts.These factors include the diameter and angle of the rock bolt installation,rock strength,grouting material,bolt material,borehole diameter,rock bolt preload,normal stress,joint surface roughness and joint expansion angle.The paper reviews the improvement of mechanical parameter setting in numerical simulation of rock bolt shear.Furthermore,it delves into the optimization of the analytical model concerning rock bolt shear theory,approached from the perspectives of both Elastic foundation beam theory coupled with Elastoplasticity theory and Structural mechanic methods.The significance of this review lies in its ability to provide insights into the mechanical behavior of rock bolts.The paper also highlights the limitations of current research and guidelines for further research of rock bolts.展开更多
Cortical electrodes are a powerful tool for the stimulation and/or recording of electrical activity in the nervous system.However,the inevitable wound caused by surgical implantation of electrodes presents bacterial i...Cortical electrodes are a powerful tool for the stimulation and/or recording of electrical activity in the nervous system.However,the inevitable wound caused by surgical implantation of electrodes presents bacterial infection and inflammatory reaction risks associated with foreign body exposure.Moreover,inflammation of the wound area can dramatically worsen in response to bacterial infection.These consequences can not only lead to the failure of cortical electrode implantation but also threaten the lives of patients.Herein,we prepared a hydrogel made of bacterial cellulose(BC),a flexible substrate for cortical electrodes,and further loaded antibiotic tetracycline(TC)and the anti-inflammatory drug dexamethasone(DEX)onto it.The encapsulated drugs can be released from the BC hydrogel and effectively inhibit the growth of Gram-negative and Gram-positive bacteria.Next,therapeutic cortical electrodes were developed by integrating the drug-loaded BC hydrogel and nine-channel serpentine arrays;these were used to record electrocorticography(ECoG)signals in a rat model.Due to the controlled release of TC and DEX from the BC hydrogel substrate,therapeutic cortical electrodes can alleviate or prevent symptoms associated with the bacterial infection and inflammation of brain tissue.This approach facilitates the development of drug delivery electrodes for resolving complications caused by implantable electrodes.展开更多
Polypropylene(PP)fiber-reinforced cement-based tailings backfill(FRCTB)is a green compound material with superior crack resistance and has good prospects for application in underground mining.However,FRCTB exhibits su...Polypropylene(PP)fiber-reinforced cement-based tailings backfill(FRCTB)is a green compound material with superior crack resistance and has good prospects for application in underground mining.However,FRCTB exhibits susceptibility to dynamic events,such as impact ground pressure and blast vibrations.This paper investigates the energy and crack distribution behavior of FRCTB under dynamic impact,considering the height/diameter(H/D)effect.Split Hopkinson pressure bar,industrial computed tomography scan,and scanning electron microscopy(SEM)experiments were carried out on six types of FRCTB.Laboratory outcomes confirmed fiber aggregation at the bottom of specimens.When H/D was less than 0.8,the proportion of PP fibers distributed along theθangle direction of80°-90°increased.For the total energy,all samples presented similar energy absorption,reflectance,and transmittance.However,a rise in H/D may cause a rise in the energy absorption rate of FRCTB during the peak phase.A positive correlation existed between the average strain rate and absorbed energy per unit volume.The increase in H/D resulted in a decreased crack volume fraction of FRCTB.When the H/D was greater than or equal to 0.7,the maximum crack volume fraction of FRCTB was observed close to the incidence plane.Radial cracks were present only in the FRCTB with an H/D ratio of 0.5.Samples with H/D ratios of 0.5 and 0.6 showed similar distributions of weakly and heavily damaged areas.PP fibers can limit the emergence and expansion of cracks by influencing their path.SEM observations revealed considerable differences in the bonding strengths between fibers and the FRCTB.Fibers that adhered particularly well to the substrate were attracted together with the hydration products adhering to surfaces.These results show that FRCTB is promising as a sustainable and green backfill for determining the design properties of mining with backfill.展开更多
Endangered species generally have small populations with low genetic diversity and a high genetic load.Thuja sutchuenensis is an endangered conifer endemic to southwestern China.It was once considered extinct in the w...Endangered species generally have small populations with low genetic diversity and a high genetic load.Thuja sutchuenensis is an endangered conifer endemic to southwestern China.It was once considered extinct in the wild,but in 1999 was rediscovered.However,little is known about its genetic load.We collected 67 individuals from five wild,isolated T.sutchuenensis populations,and used 636,151 SNPs to analyze the level of genetic diversity and genetic load in T.sutchuenensis to delineate the conservation units of T.sutchuenensis,based on whole transcriptome sequencing data,as well as target capture sequencing data.We found that populations of T.sutchuenensis could be divided into three groups.These groups had low levels genetic diversity and were moderately genetically differentiated.Our findings also indicate that T.sutchuenensis suffered two severe bottlenecks around the Last Glaciation Period and Last Glacial Maximum.Among Thuja species,T.sutchuenensis presented the lowest genetic load and hence might have purged deleterious mutations efficiently through purifying selection.However,distribution of fitness effects analysis indicated a high extinction risk for T.sutchuenensis.Multiple lines of evidence identified three management units for T.sutchuenensis.Although T.sutchuenensis possesses a low genetic load,low genetic diversity,suboptimal fitness,and anthropogenic pressures all present an extinction risk for this rare conifer.This might also hold true for many endangered plant species in the mountains all over the world.展开更多
Investigating natural-inspired applications is a perennially appealing subject for scientists. The current increase in the speed of natural-origin structure growth may be linked to their superior mechanical properties...Investigating natural-inspired applications is a perennially appealing subject for scientists. The current increase in the speed of natural-origin structure growth may be linked to their superior mechanical properties and environmental resilience. Biological composite structures with helicoidal schemes and designs have remarkable capacities to absorb impact energy and withstand damage. However, there is a dearth of extensive study on the influence of fiber redirection and reorientation inside the matrix of a helicoid structure on its mechanical performance and reactivity. The present study aimed to explore the static and transient responses of a bio-inspired helicoid laminated composite(B-iHLC) shell under the influence of an explosive load using an isomorphic method. The structural integrity of the shell is maintained by a viscoelastic basis known as the Pasternak foundation, which encompasses two coefficients of stiffness and one coefficient of damping. The equilibrium equations governing shell dynamics are obtained by using Hamilton's principle and including the modified first-order shear theory,therefore obviating the need to employ a shear correction factor. The paper's model and approach are validated by doing numerical comparisons with respected publications. The findings of this study may be used in the construction of military and civilian infrastructure in situations when the structure is subjected to severe stresses that might potentially result in catastrophic collapse. The findings of this paper serve as the foundation for several other issues, including geometric optimization and the dynamic response of similar mechanical structures.展开更多
Rock-encased-backfill(RB)structures are common in underground mining,for example in the cut-andfill and stoping methods.To understand the effects of cyclic excavation and blasting activities on the damage of these RB ...Rock-encased-backfill(RB)structures are common in underground mining,for example in the cut-andfill and stoping methods.To understand the effects of cyclic excavation and blasting activities on the damage of these RB structures,a series of triaxial stepwise-increasing-amplitude cyclic loading experiments was conducted with cylindrical RB specimens(rock on outside,backfill on inside)with different volume fractions of rock(VF=0.48,0.61,0.73,and 0.84),confining pressures(0,6,9,and 12 MPa),and cyclic loading rates(200,300,400,and 500 N/s).The damage evolution and meso-crack formation during the cyclic tests were analyzed with results from stress-strain hysteresis loops,acoustic emission events,and post-failure X-ray 3D fracture morphology.The results showed significant differences between cyclic and monotonic loadings of RB specimens,particularly with regard to the generation of shear microcracks,the development of stress memory and strain hardening,and the contact forces and associated friction that develops along the rock-backfill interface.One important finding is that as a function of the number of cycles,the elastic strain increases linearly and the dissipated energy increases exponentially.Also,compared with monotonic loading,the cyclic strain hardening characteristics are more sensitive to rising confining pressures during the initial compaction stage.Another finding is that compared with monotonic loading,more shear microcracks are generated during every reloading stage,but these microcracks tend to be dispersed and lessen the likelihood of large shear fracture formation.The transition from elastic to plastic behavior varies depending on the parameters of each test(confinement,volume fraction,and cyclic rate),and an interesting finding was that the transformation to plastic behavior is significantly lower under the conditions of 0.73 rock volume fraction,400 N/s cyclic loading rate,and 9 MPa confinement.All the findings have important practical implications on the ability of backfill to support underground excavations.展开更多
文摘Bituminous materials are heat-sensitive, and their mechanical properties vary with temperature. This variation in properties is not without consequences on the performance of flexible road structures under the repeated passage of multi-axles. This study determines the influence of seasonal variations on the rate of permanent deformation, the rut depth of flexible pavements and the effect of alternating loading of heavy goods vehicles following the temperature variations on the durability of roads. Thus, an ambient and pavement surface temperature measurement was carried out in 2022. The temperature profile at different layers of the modelled pavement, the evaluation of deformation rates and rutting depth were determined using several models. The results show that the permanent deformation and rutting rates are higher at the level of the bituminous concrete layer than at the level of the asphalt gravel layer because the stresses decrease from the surface to the depth of the pavement. On the other hand, the variations in these rates, permanent deformations and ruts between the hot and so-called cold periods are more pronounced in the bitumen gravel than in bituminous concrete, showing that gravel bitumen is more sensitive to temperature variations than bituminous concrete despite its higher rigidity. Of these results, we suggested a periodic and alternating loading of the different types of heavy goods vehicles. These loads consist of fully applying the WAEMU standards with a tolerance of 15% during periods of high and low temperatures. This regulation has increased 2 to 3 times in the durability of roadways depending on the type of heavy goods vehicle.
文摘The multiplication of heavy vehicle axles and road overloads are phenomena that are becoming increasingly important on the road network of the WAEMU community. These phenomena, although framed by standards, have an impact on the durability of pavements. In this manuscript it is a question of evaluating the life of the road under the effect of traffic of these multi-axle vehicles and the different tolerances of overloads observed on the road network. To achieve this, a modeling of a bituminous pavement was made with the software ALIZE Lcpc Version 231 based on the principle of the French method of sizing. An inventory of multi-axle heavy goods vehicles was also made on a road with a weighing station. This traffic counting made it possible to classify heavy goods vehicles into three categories, namely: 1) trucks, 2) dual-wheeled semi-trailers and 3) single-wheeled semi-trailers. The results obtained show that in terms of aggressiveness, single-wheeled semi-trailers are the most aggressive, followed by heavy goods vehicles in the category of trucks with more than five axles and semi-trailers with dual wheels with more than seven axles. The durability of the road depends on the aggressiveness of heavy goods vehicles, it was found that the tolerance threshold for overloads of 15% of the total permissible rolling weight (TARW) or the total permissible laden weight (TALW) currently granted in the Community area needs to be reviewed. For durable road surfaces, this tolerance may only be allowed for heavy goods vehicles of type P11, P12 and P13. The 5% tolerance can be applied to all vehicles except heavy goods vehicles with single wheels.
基金supported by the National Natural Science Foundation of China(Nos.52074151,51927807,and 52274123)Tiandi Science and Technology Co.,Ltd.(No.2022-2-TDMS012)。
文摘This study explores the effects of dynamic and static loading on rock bolt performance a key factor in maintaining the structural safety of coal mine roadways susceptible to coal bursts.Employing a housemade load frame to simulate various failure scenarios,pretension-impact-pull tests on rock bolts were conducted to scrutinize their dynamic responses under varied static load conditions and their failure traits under combined loads.The experimental results denote that with increased impact energy,maximum and average impact loads on rock bolts escalate significantly under pretension,initiating plastic deformation beyond a certain threshold.Despite minor reductions in the yield load due to impactinduced damage,pretension aids in constraining post-impact deformation rate and fluctuation degree of rock bolts.Moreover,impact-induced plastic deformation causes internal microstructure dislocation,fortifying the stiffness of the rock bolt support system.The magnitude of this fortification is directly related to the plastic deformation induced by the impact.These findings provide crucial guidance for designing rock bolt support in coal mine roadway excavation,emphasizing the necessity to consider both static and dynamic loads for improved safety and efficiency.
基金the financial support from the National Natural Science Foundation of China(Nos.52374094,52174122 and 52374218)Excellent Youth Fund of Shandong Natural Science Foundation(No.ZR2022YQ49)Taishan Scholar Project in Shandong Province(Nos.tspd20210313 and tsqn202211150)。
文摘The stability control of fissured rock is difficult,especially under static and dynamic loads in deep coal mines.In this paper,the dynamic mechanical properties,strain rate evolution and energy dissipation of fissured and anchored rocks were respectively obtained by SHPB tests.It was found that bolt can provide supporting efficiency-improving effect for fissured rock against dynamic disturbance,and this effect increased quadratically with decrease in anchoring angles.Then,the energy dissipation mechanism of anchored rock was obtained by slipping model.Furthermore,bolt energy-absorbing mechanism by instantaneous tensile-shear deformation was expressed based on material mechanics,which was the larger the anchoring angle,the smaller the energy absorption,and the less the contribution to supporting efficiency improvement.On this basis,the functional relationship between energy dissipation of anchored rock and energy absorption of bolt was established.Taking the coal-gangue separation system of Longgu coal mine as an example,the optimal anchoring angle can be determined as 57.5°–67.5°.Field monitoring showed fissured rock with the optimal anchoring angle,can not only effectively control the deformation,but also fully exert the energy-absorbing and efficiency-improving effect of bolt itself.This study provides guidance to the stability control and supporting design for deep engineering under the same or similar conditions.
基金l’UniversitéLaval for the financial support of his sabbatical year at Dipartimento di Bioscienze e Territorio,Universitàdegli Studi del Molise in Campobasso,Italy。
文摘This work presents a novel approach to the dynamic response analysis of a Euler-Bernoulli beam resting on a Winkler soil model and subjected to an impact loading.The approach considers that damping has much less importance in controlling the maximum response to impulsive loadings because the maximum response is reached in a very short time,before the damping forces can dissipate a significant portion of the energy input into the system.The development of two sine series solutions,relating to different types of impulsive loadings,one involving a single concentrated force and the other a distributed line load,are presented.This study revealed that when a simply supported Euler-Bernoulli beam,resting on a Winkler soil model,is subject to an impact load,the resulting vertical displacements,bending moments and shear forces produced along the span of the beam are considerably affected.In particular,the quantification of this effect is best observed,relative to the corresponding static solution,via an amplification factor.The computed impact amplification factors,for the sub-grade moduli used in this study,were in magnitude greater than 2,thus confirming the multiple-degree-of-freedom nature of the problem.
基金This research was funded through the National Natural Science Foundation of China(Grant Nos.52108299 and 52178312)the China Postdoctoral Science Foundation(Grant No.2021M693740)the Basal Research Fund Support by Chongqing University.
文摘The performance of geosynthetic-reinforced embankments under traffic moving loads is always a hotspot in the geotechnical engineering field.A three-dimensional(3D)model of a geosynthetic-reinforced embankment without drainage consolidation was established using the finite element software ABAQUS.In this model,the traffic loads were simulated by two moving loads of rectangular pattern,and their amplitude,range,and moving speed were realized by a Fortran subroutine.The embankment fill was simulated by an equivalent linear viscoelastic model,which can reflect its viscoelasticity.The geogrid was simulated by the truss element,and the geocell was simulated by the membrane element.Infinite elements were utilized to weaken the boundary effect caused by the model geometry at the boundaries.Validation of the established numerical model was conducted by comparing the predicted deformations in the cross-section of the geosynthetic-reinforced embankment with those from the existing literature.On this basis,the dynamic stress and strain distribution in the pavement structure layer of the geosynthetic-reinforced embankment under a moving load was also analyzed.Finally,a parametric study was conducted to examine the influences of the different types of reinforcement,overload,and the moving load velocity on the geosynthetic-reinforced embankment.
基金supported by JUST start-up fund for science research,the Jiangsu Natural Science Foundation(Grant No.BK20210885).
文摘According to the established prediction model of internal solitary wave loads on FPSO in the previous work,the lumped mass model and the movement equations of finite displacement in time domain,the dynamic response model of interaction between internal solitary waves and FPSO with mooring lines were established.Through calculations and analysis,time histories of dynamic loads of FPSO exerted by internal solitary waves,FPSO’s motion and dynamic tension of mooring line were obtained.The effects of the horizontal pretension of mooring line,the amplitude of internal solitary wave and layer fluid depth on dynamic response behavior of FPSO were mastered.It was shown that the internal solitary waves had significant influence on FPSO,such as the large magnitude horizontal drift and a sudden tension increment.With internal solitary wave of −170 m amplitude in the ocean with upper and lower layer fluid depth ratio being 60:550,the dynamic loads reached 991.132 kN(horizontal force),18067.3 kN(vertical force)and−5042.92 kN·m(pitching moment).Maximum of FPSO’s horizontal drift was 117.56 m.Tension increment of upstream mooring line approached 401.48 kN and that of backflow mooring line was−140 kN.Moreover,the loads remained nearly constant with different pretension but increased obviously with the changing amplitude and layer fluid depth ratio.Tension increments of mooring lines also changed little with the pretension but increased rapidly when amplitude and layer fluid depth ratio increased.However,FPSO’s motion increased quickly with not only the horizontal pretension but also the amplitude of internal solitary wave and layer fluid depth ratio.
基金support of RSSB to this work via the project RSSB/COF-UOH-49 is greatly appreciated.The authors also acknowledge the support by FCT,through IDMEC,under LAETA,project UIDB/50022/2020.
文摘Appropriate interaction between pantograph and catenary is imperative for smooth operation of electric trains.Changing heights of overhead lines to accommodate level crossings,overbridges,and tunnels pose significant challenges in maintaining consistent current collection performance as the pantograph aerodynamic profile,and thus aerodynamic load changes significantly with operational height.This research aims to analyse the global flow characteristics and aerodynamic forces acting on individual components of an HSX pantograph operating in different configurations and orientations,such that the results can be combined with multibody simulations to obtain accurate dynamic insight into contact forces.Specifically,computational fluid dynamics simulations are used to investigate the pantograph component loads in a representative setting,such as that of the recessed cavity on a Class 800 train.From an aerodynamic perspective,this study indicates that the total drag force acting on non-fixed components of the pantograph is larger for the knuckle-leading orientation rather than the knuckle-trailing,although the difference between the two is found to reduce with increasing pantograph extension.Combining the aerodynamic loads acting on individual components with multibody tools allows for realistic dynamic insight into the pantograph behaviour.The results obtained show how considering aerodynamic forces enhance the realism of the models,leading to behaviour of the pantograph-catenary contact forces closely matching that seen in experimental tests.
基金funded from the European Union's Horizon 2020 research and innovation programme in the project In2Track3 under grant agreement No.101012456.
文摘Dynamic wheel-rail contact forces induced by a severe form of wheel tread damage have been measured by a wheel impact load detector during full-scale field tests at different vehicle speeds.Based on laser scanning,the measured three-dimensional damage geometry is employed in simulations of dynamic vehicle-track interaction to calibrate and verify a simulation model.The relation between the magnitude of the impact load and various operational parameters,such as vehicle speed,lateral position of wheel-rail contact,track stiffness and position of impact within a sleeper bay,is investigated.The calibrated model is later employed in simulations featuring other forms of tread damage;their effects on impact load and subsequent fatigue impact on bearings,wheel webs and subsurface initiated rolling contact fatigue of the wheel tread are assessed.The results quantify the effects of wheel tread defects and are valuable in a shift towards condition-based maintenance of running gear,and for general assessment of the severity of different types of railway wheel tread damage.
基金the National Natural Science Foundation of China Youth Fund,Research on Security Low Carbon Collaborative Situation Awareness of Comprehensive Energy System from the Perspective of Dynamic Security Domain(52307130).
文摘To address the issues of limited demand response data,low generalization of demand response potential evaluation,and poor demand response effect,the article proposes a demand response potential feature extraction and prediction model based on data mining and a demand response potential assessment model for adjustable loads in demand response scenarios based on subjective and objective weight analysis.Firstly,based on the demand response process and demand response behavior,obtain demand response characteristics that characterize the process and behavior.Secondly,establish a feature extraction and prediction model based on data mining,including similar day clustering,time series decomposition,redundancy processing,and data prediction.The predicted values of each demand response feature on the response day are obtained.Thirdly,the predicted data of various characteristics on the response day are used as demand response potential evaluation indicators to represent different demand response scenarios and adjustable loads,and a demand response potential evaluation model based on subjective and objective weight allocation is established to calculate the demand response potential of different adjustable loads in different demand response scenarios.Finally,the effectiveness of the method proposed in the article is verified through examples,providing a reference for load aggregators to formulate demand response schemes.
基金Supported by Grants of J-milk(Japan Dairy Association)。
文摘BACKGROUND Lactose intolerance(LI)is commonly seen in East Asian countries.Several studies showed that lactose or milk loading has been used as a treatment for lactose malabsorption(LM)in Western countries,but there have been no reports regarding this type of treatment in Japan.As lactose or milk loading requires ingestion of large amounts of lactose within a short period,this is considered to be too harsh for Japanese people because of their less habitual milk consumption(175 mL per day in average)than Western people.In this study,we demonstrated lactose tolerance acquisition in a suitable way for Japanese.AIM To examine the efficacy of lactose(cow’s milk)loading treatment in patients with LM.METHODS Individuals with abdominal symptoms induced by milk or dairy products(LI symptoms)were identified with a questionnaire.A 20 g lactose hydrogen breath test(LHBT)was carried out to confirm LM diagnosis and to evaluate co-existence of small intestinal bacterial overgrowth(SIBO).Respondents diagnosed with LM were selected as study subjects and were treated with incremental loads of cow’s milk,starting from 30 mL and increasing up to 200 mL at 4-7 d intervals.After the treatment,changes in symptoms and LM diagnostic value of 20 g LHBT were investigated.Stool samples pre-and post-treatment were examined for changes in intestinal microbiota using 16S rRNA sequencing.Informed consent was obtained prior to each stage of the study.RESULTS In 46 subjects with LI symptoms(10-68 years old,mean age 34 years old)identified with the questionnaire,35(76.1%)were diagnosed with LM by 20 g LHBT,and 6 had co-existing SIBO.The treatment with incremental cow’s milk was carried out in 32 subjects diagnosed with LM(14-68 years old,median age 38.5 years old).The mean period of the treatment was 41±8.6 d.Improvement of symptoms was observed in 29(90.6%;95%confidence interval:75.0%-98.0%)subjects.Although 20 g LHBT indicated that 10(34.5%)subjects had improved diagnostic value of LM,no change was observed in 16(55.2%)subjects.Analysis of the fecal intestinal microbiota showed a significant increase in Blautia in 7 subjects who became symptom-free after the treatment(P=0.0313).CONCLUSION LM was diagnosed in approximately 75%of the subjects who had LI.Incremental loads of cow’s milk is regarded as a useful treatment for LM without affecting everyday life.
文摘Heterogeneous brittle geomaterials are highly susceptible to cyclic loads.They contain inherent flaws and cracks that grow under fatigue loads and lead to failure.This study presents a numerical model for analyzing fatigue in these materials based on the two-dimensional(2D)boundary element method and linear elastic fracture mechanics.The process is formulated by coupling the displacement discontinuity method with the incorporation technique of dissimilar regions and the governing equations of fatigue.The heterogeneous media are assumed to consist of materials with different properties,and the interfaces are assumed to be completely bonded.In addition,the domains include multiple cracks exposed to constant and variable amplitude cyclic loads.The stress intensity factor is a crucial parameter in fatigue analysis,which is determined using the displacement field around crack tips.An incremental crack growth scheme is applied to calculating the fatigue life.The growth rate values are employed to estimate the length of crack extension when there are multiple cracks.The interaction between cracks is considered,which also includes the coalescence phenomenon.Finally,various structures under different cyclic loads are examined to evaluate the accuracy of this method.The results demonstrate the efficiency of the proposed approach in modeling fatigue crack growth and life estimation.The behavior of life curves for the heterogeneous domain was as expected.These curves illustrate the breakpoints caused by utilizing discrete incremental life equations.At these points,the trend of the curves changed with the material properties and fatigue characteristics of the new material around the crack tips.
文摘Industrial production of chemical cement leads to extreme emissions of greenhouse gases.Biological or bioinspired sustainable materials for soil treatment projects can be employed instead of chemical cement to heal the carbon cycle in the ecosystem.The enzyme-induced calcite precipitation(EICP)method is one of the novel bio-inspired technologies that can be employed in soil treatment projects to increase desired properties of soils.While the monotonic and cyclic behavior of the enzymatically treated sands has been investigated comprehensively,the strain accumulation pattern in these improved soils under cyclic traffic loads has not been evaluated yet.In this paper,confined and unconfined cyclic compression tests are applied to the enzymatically lightly cemented sands,and the effects of the different parameters on their strain accumulation pattern are investigated for the first time in the literature.This study uses two types of specimens with unconfined compression strengths(UCS)equal to 42 kPa and 266 kPa.It is shown that the treated specimens have a rate-dependent behavior where cyclic loads with low frequencies lead to more resilient and plastic strains in the specimens.The results show that by approaching the maximum applied stresses to the UCS of the specimens(by breaking more calcite bonds between sand particles),the rate dependency behavior of specimens will reduce.Investigation of the effects of the cementation level demonstrated that by increasing the amount of the precipitated calcite from 0.38%to 0.83%,accumulated plastic strains are reduced almost 95%under the same loading condition.Effects of the initial static loads,confining pressures,the number of cycles,and amplitudes of the cyclic loads are also evaluated.
基金This paper is financially supported by the National Natural Science Foundation of China(Grant Nos.52074263 and 52034007)the Postgraduate Research and Practice Innovation Program of Jiangsu Province(Grant No.KYCX21_2332).
文摘Dynamic load on anchoring structures(AS)within deep roadways can result in cumulative damage and failure.This study develops an experimental device designed to test AS under triaxial loads.The device enables the investigation of the mechanical response,failure mode,instability assessment criteria,and anchorage effect of AS subjected to combined cyclic dynamic-static triaxial stress paths.The results show that the peak bearing strength is positively correlated with the anchoring matrix strength,anchorage length,and edgewise compressive strength.The bearing capacity decreases significantly when the anchorage direction is severely inclined.The free face failure modes are typically transverse cracking,concave fracturing,V-shaped slipping and detachment,and spallation detachment.Besides,when the anchoring matrix strength and the anchorage length decrease while the edgewise compressive strength,loading rate,and anchorage inclination angle increase,the failure intensity rises.Instability is determined by a negative tangent modulus of the displacement-strength curve or the continued deformation increase against the general downward trend.Under cyclic loads,the driving force that breaks the rock mass along the normal vector and the rigidity of the AS are the two factors that determine roadway stability.Finally,a control measure for surrounding rock stability is proposed to reduce the internal driving force via a pressure relief method and improve the rigidity of the AS by full-length anchorage and grouting modification.
基金The Project(52174101)supported by the National Natural Science Foundation of ChinaThe Project(2023A1515011634)supported by Guangdong Basic and Applied Basic Research Foundation.
文摘Rock bolts are extensively utilized in underground engineering as a means of offering support and stability to rock masses in tunnels,mines,and other underground structures.In environments of high ground stress,faults or weak zones can frequently arise in rock formations,presenting a significant challenge for engineering and potentially leading to underground engineering collapse.Rock bolts serve as a crucial structural element for the transmission of tensile stress and are capable of withstanding shear loads to prevent sliding of weak zones within rock mass.Therefore,a complete understanding of the behavior of rock bolts subjected to shear loads is essential.This paper presents a state-of-the-art review of the research progress of rock bolts subjected to shear load in three categories:experiment,numerical simulation,and analytical model.The review focuses on the research studies and developments in this area since the 1970s,providing a comprehensive overview of numerous factors that influence the anchorage performance of rock bolts.These factors include the diameter and angle of the rock bolt installation,rock strength,grouting material,bolt material,borehole diameter,rock bolt preload,normal stress,joint surface roughness and joint expansion angle.The paper reviews the improvement of mechanical parameter setting in numerical simulation of rock bolt shear.Furthermore,it delves into the optimization of the analytical model concerning rock bolt shear theory,approached from the perspectives of both Elastic foundation beam theory coupled with Elastoplasticity theory and Structural mechanic methods.The significance of this review lies in its ability to provide insights into the mechanical behavior of rock bolts.The paper also highlights the limitations of current research and guidelines for further research of rock bolts.
基金support from the National Natural Science Foundation of China(Nos.52073230,62204204,and 62288102)the Shaanxi Provincial Science Fund for Distinguished Young Scholars(No.2023-JC-JQ-32)+2 种基金the Science and Technology Innovation 2030-Major Project(No.2022ZD0208601)the Shanghai Sailing Program(No.21YF1451000)the China National Postdoctoral Program for Innovative Talents(No.BX20230494).
文摘Cortical electrodes are a powerful tool for the stimulation and/or recording of electrical activity in the nervous system.However,the inevitable wound caused by surgical implantation of electrodes presents bacterial infection and inflammatory reaction risks associated with foreign body exposure.Moreover,inflammation of the wound area can dramatically worsen in response to bacterial infection.These consequences can not only lead to the failure of cortical electrode implantation but also threaten the lives of patients.Herein,we prepared a hydrogel made of bacterial cellulose(BC),a flexible substrate for cortical electrodes,and further loaded antibiotic tetracycline(TC)and the anti-inflammatory drug dexamethasone(DEX)onto it.The encapsulated drugs can be released from the BC hydrogel and effectively inhibit the growth of Gram-negative and Gram-positive bacteria.Next,therapeutic cortical electrodes were developed by integrating the drug-loaded BC hydrogel and nine-channel serpentine arrays;these were used to record electrocorticography(ECoG)signals in a rat model.Due to the controlled release of TC and DEX from the BC hydrogel substrate,therapeutic cortical electrodes can alleviate or prevent symptoms associated with the bacterial infection and inflammation of brain tissue.This approach facilitates the development of drug delivery electrodes for resolving complications caused by implantable electrodes.
基金financially supported by the National Key Research and Development Program of China(No.2022YFC2905004)the China Postdoctoral Science Foundation(No.2023M742134)。
文摘Polypropylene(PP)fiber-reinforced cement-based tailings backfill(FRCTB)is a green compound material with superior crack resistance and has good prospects for application in underground mining.However,FRCTB exhibits susceptibility to dynamic events,such as impact ground pressure and blast vibrations.This paper investigates the energy and crack distribution behavior of FRCTB under dynamic impact,considering the height/diameter(H/D)effect.Split Hopkinson pressure bar,industrial computed tomography scan,and scanning electron microscopy(SEM)experiments were carried out on six types of FRCTB.Laboratory outcomes confirmed fiber aggregation at the bottom of specimens.When H/D was less than 0.8,the proportion of PP fibers distributed along theθangle direction of80°-90°increased.For the total energy,all samples presented similar energy absorption,reflectance,and transmittance.However,a rise in H/D may cause a rise in the energy absorption rate of FRCTB during the peak phase.A positive correlation existed between the average strain rate and absorbed energy per unit volume.The increase in H/D resulted in a decreased crack volume fraction of FRCTB.When the H/D was greater than or equal to 0.7,the maximum crack volume fraction of FRCTB was observed close to the incidence plane.Radial cracks were present only in the FRCTB with an H/D ratio of 0.5.Samples with H/D ratios of 0.5 and 0.6 showed similar distributions of weakly and heavily damaged areas.PP fibers can limit the emergence and expansion of cracks by influencing their path.SEM observations revealed considerable differences in the bonding strengths between fibers and the FRCTB.Fibers that adhered particularly well to the substrate were attracted together with the hydration products adhering to surfaces.These results show that FRCTB is promising as a sustainable and green backfill for determining the design properties of mining with backfill.
基金This study was financially supported by National Natural Science Foundation of China(grant No.U20A2080,31622015)the Institutional Research Fund from Sichuan University(2021SCUNL102)Fundamental Research Fund for the Central Universities of China(SCU 2021D006,SCU 2022D003).
文摘Endangered species generally have small populations with low genetic diversity and a high genetic load.Thuja sutchuenensis is an endangered conifer endemic to southwestern China.It was once considered extinct in the wild,but in 1999 was rediscovered.However,little is known about its genetic load.We collected 67 individuals from five wild,isolated T.sutchuenensis populations,and used 636,151 SNPs to analyze the level of genetic diversity and genetic load in T.sutchuenensis to delineate the conservation units of T.sutchuenensis,based on whole transcriptome sequencing data,as well as target capture sequencing data.We found that populations of T.sutchuenensis could be divided into three groups.These groups had low levels genetic diversity and were moderately genetically differentiated.Our findings also indicate that T.sutchuenensis suffered two severe bottlenecks around the Last Glaciation Period and Last Glacial Maximum.Among Thuja species,T.sutchuenensis presented the lowest genetic load and hence might have purged deleterious mutations efficiently through purifying selection.However,distribution of fitness effects analysis indicated a high extinction risk for T.sutchuenensis.Multiple lines of evidence identified three management units for T.sutchuenensis.Although T.sutchuenensis possesses a low genetic load,low genetic diversity,suboptimal fitness,and anthropogenic pressures all present an extinction risk for this rare conifer.This might also hold true for many endangered plant species in the mountains all over the world.
文摘Investigating natural-inspired applications is a perennially appealing subject for scientists. The current increase in the speed of natural-origin structure growth may be linked to their superior mechanical properties and environmental resilience. Biological composite structures with helicoidal schemes and designs have remarkable capacities to absorb impact energy and withstand damage. However, there is a dearth of extensive study on the influence of fiber redirection and reorientation inside the matrix of a helicoid structure on its mechanical performance and reactivity. The present study aimed to explore the static and transient responses of a bio-inspired helicoid laminated composite(B-iHLC) shell under the influence of an explosive load using an isomorphic method. The structural integrity of the shell is maintained by a viscoelastic basis known as the Pasternak foundation, which encompasses two coefficients of stiffness and one coefficient of damping. The equilibrium equations governing shell dynamics are obtained by using Hamilton's principle and including the modified first-order shear theory,therefore obviating the need to employ a shear correction factor. The paper's model and approach are validated by doing numerical comparisons with respected publications. The findings of this study may be used in the construction of military and civilian infrastructure in situations when the structure is subjected to severe stresses that might potentially result in catastrophic collapse. The findings of this paper serve as the foundation for several other issues, including geometric optimization and the dynamic response of similar mechanical structures.
基金We acknowledge the funding support from the National Natural Science Foundation of China Youth Fund(Grant No.52004019)the National Natural Science Foundation of China(Grant No.41825018)China Postdoctoral Science Foundation(Grant No.2023M733481).
文摘Rock-encased-backfill(RB)structures are common in underground mining,for example in the cut-andfill and stoping methods.To understand the effects of cyclic excavation and blasting activities on the damage of these RB structures,a series of triaxial stepwise-increasing-amplitude cyclic loading experiments was conducted with cylindrical RB specimens(rock on outside,backfill on inside)with different volume fractions of rock(VF=0.48,0.61,0.73,and 0.84),confining pressures(0,6,9,and 12 MPa),and cyclic loading rates(200,300,400,and 500 N/s).The damage evolution and meso-crack formation during the cyclic tests were analyzed with results from stress-strain hysteresis loops,acoustic emission events,and post-failure X-ray 3D fracture morphology.The results showed significant differences between cyclic and monotonic loadings of RB specimens,particularly with regard to the generation of shear microcracks,the development of stress memory and strain hardening,and the contact forces and associated friction that develops along the rock-backfill interface.One important finding is that as a function of the number of cycles,the elastic strain increases linearly and the dissipated energy increases exponentially.Also,compared with monotonic loading,the cyclic strain hardening characteristics are more sensitive to rising confining pressures during the initial compaction stage.Another finding is that compared with monotonic loading,more shear microcracks are generated during every reloading stage,but these microcracks tend to be dispersed and lessen the likelihood of large shear fracture formation.The transition from elastic to plastic behavior varies depending on the parameters of each test(confinement,volume fraction,and cyclic rate),and an interesting finding was that the transformation to plastic behavior is significantly lower under the conditions of 0.73 rock volume fraction,400 N/s cyclic loading rate,and 9 MPa confinement.All the findings have important practical implications on the ability of backfill to support underground excavations.