Research on the Deep Integration Mechanism of National Fitness Campaign and College Physical Education Teaching:Taking Guangdong University of Science and Technology as an Example

By using the methods of literature review,questionnaire survey,and expert interview,this paper discusses and analyzes the deep integration mechanism of national fitness campaign and college physical education teaching,in order to promote the development of college physical education teaching reform,expand ideas,explore new fields,and provide novel development directions.The purpose is to enhance the national physical quality,improve the public service system,enhance the health awareness of the citizens,and provide guidelines for promoting the development of sports.

Research on Mechanism and Promotion Path of Culture and Tourism Industry Integration in Tai'an City

Based on in-depth analysis of dynamic mechanism of industry integration under the background of industry integration,as well as current situation and existing problems of integrated development of culture and tourism industry in Tai’an City,the paper puts forward the selection path and policy guarantee for the integrated development of culture and tourism industry in Tai’an City following the theory of industry integration and dynamic mechanism,which is of important policy guiding significance for promoting the coordinated development of culture and tourism industry in Tai’an City.

Discussion on Construction and Mechanism of Practice Bases for Professional Degree Postgraduates Based on the Integration of Production and Education in Local Universities

Under the background of emerging agricultural education,practice bases are an important place to train profession talented person that match social needs,so it is very important to build stable and long-term practice bases.At present,the main problems in the construction of practice bases for postgraduates in local colleges and universities are mainly focusing on construction and neglecting management,imperfect cooperation mechanism and lack of teaching management effectively.It is of great significance to build a long-term management mechanism to ensure the education quality of practice bases.Therefore,constructing the mode of"double integration and double promotion of production and education"with practice bases as the carrier and realizing the organic combination of industrial needs and postgraduate projects is an important idea for local colleges and universities to train professional degree postgraduates to"know agriculture,love agriculture,strengthen agriculture and promote agriculture",and it also provides a reference for the mechanism construction of postgraduate bases.

Study on the Mechanism of the Integration of Urban and Rural Development from the View of Elements Flow

Fromthe enterprise,individual and government,which are the three main economic behavior subject,this paper analysis factors impact of flow behavior main body and the change of the objective function,constraint function and the impact of the change of behavior equation,and then summarizes their effects on the integration of urban and rural development,to build fromexogenous shocks to the endogenous to adapt to the economic decision-making framework,clarify elements flow affect the running mechanismof the urban-rural integration.

The misalignment between degradation rate and mechanical integrity of Mg-Zn-Y-Nd alloy during the degradation evaluation in modified Hanks’solutions

The degradation behavior of biodegradable Mg alloys has become a research hotspot in the fields about biodegradable metallic materials.While the most of the related publications mainly focused on the degradation rate of Mg-based materials,but rare to care about the changes of their mechanical properties during the immersion period,which can significantly affect their service performance.The link between residual strength and Mg degradation is not appreciated enough.In this work,a series media were constructed based on Hanks’solution,the effects of inorganic ions on the degradation rate and mechanical integrity of Mg-Zn-Y-Nd alloy were investigated.The results indicated that the degradation behavior of Mg alloy was mainly controlled by degradation products and there is no direct correspondence between the degradation rate change and mechanical integrity of Mg alloy.The relevant findings are beneficial for selecting the monitoring index in Mg corrosion tests and evaluating the service reliability of Mg alloys for biomedical applications.

Failure mechanism and influencing factors of cement sheath integrity under alternating pressure

The failure of cement sheath integrity can be easily caused by alternating pressure during large-scale multistage hydraulic fracturing in shale-gas well.An elastic-plastic mechanical model of casing-cement sheath-formation(CSF)system under alternating pressure is established based on the Mohr-Coulomb criterion and thick-walled cylinder theory,and it has been solved by MATLAB programming combining global optimization algorithm with Global Search.The failure mechanism of cement sheath integrity is investigated,by which it can be seen that the formation of interface debonding is mainly related to the plastic strain accumulation,and there is a risk of interface debonding under alternating pressure,once the cement sheath enters plasticity whether in shallow or deep well sections.The matching relationship between the mechanical parameters(elastic modulus and Poisson's ratio)of cement sheath and its integrity failure under alternating pressure in whole well sections is studied,by which it has been found there is a“critical range”in the Poisson's ratio of cement sheath.When the Poisson's ratio is below the“critical range”,there is a positive correlation between the yield internal pressure of cement sheath(SYP)and its elastic modulus.However,when the Poisson's ratio is above the“critical range”,there is a negative correlation.The elastic modulus of cement sheath is closely related to its Poisson's ratio,and restricts each other.Scientific and reasonable matching between mechanical parameters of cement sheath and CSF system under different working conditions can not only reduce the cost,but also protect the cement sheath integrity.

A Survey of Mathematical Tools in Topology and Performance Integrated Modeling and Design of Robotic Mechanism

Topology and performance are the two main topics dealt in the development of robotic mechanisms.However,it is still a challenge to connect them by integrating the modeling and design process of both parts in a unified frame.As the properties associated with topology and performance,finite motion and instantaneous motion of the robot play key roles in the procedure.On the purpose of providing a fundamental preparation for integrated modeling and design,this paper carries out a review on the existing unified mathematic frameworks for motion description and computation,involving matrix Lie group and Lie algebra,dual quaternion and pure dual quaternion,finite screw and instantaneous screw.Besides the application in robotics,the review of the work from these mathematicians concentrates on the description,composition and intersection operations of the finite and instantaneous motions,especially on the exponential-differential maps which connect the two sides.Furthermore,an in-depth discussion is worked out by investigating the algebraical relationship among these methods and their further progress in integrated robotic development.The presented review offers insightful investigation to the motion description and computation,and therefore would help designers to choose appropriate mathematical tool in the integrated design and modeling and design of mechanisms and robots.

The Application of Semantic Cognitive Mechanism of English Idioms in Idiom Teaching

This article takes the perspective of cognitive linguistics and applies the semantic cognitive mechanism of English idioms to analyze the motivation between the generation and meaning of idioms.It explores the teaching of English idioms based on motivation analysis and proposes several suggestions and strategies for idiom teaching,hoping to benefit English idiom teaching.

Integrating Automatic Patch Snatching System by the Concept of Generalized Mechanisms

An automatic patch snatching system is described which has three machine cells including dividing equipment, tackling equipment and patch removing equipment. The electromechanical integration design of in-piece tackling system based on the concept of generalized mechanisms is introduced. The design of the dividing equipment, the design of micro-feeding machine equipped with micro-level pressure sensor, and the realizing of computer path for patch snatching are investigated.

Research on the mechanism of Chaihu Huangqin medicine based on integrated pharmacology to improve the clinical symptoms of COVID-19

Objective:Novel coronavirus(COVID-19)was used to improve the clinical symptoms of the new type coronavirus(LV),based on integrated pharmacology.Methods:TCMIP v2.0 was used to predict the key target and action pathway of Bupleurum baicalensis Georgi in improving the clinical symptoms of covid-19.The multi-dimensional network diagram of"drug pair active component key target action pathway"was drawn to explore its action mechanism from the molecular level.Results:Bupleurum and Scutellaria baicalensis could regulate IL signaling pathway and clec7a(a member of C-type lectin domain 7 family)/Inflammatory pathway,immune stress and other related signaling pathways can inhibit activated cytokines,alleviate excessive immune response,eliminate inflammation,and resist virus.In addition,the core targets of Bupleurum baicalensis baicalensis Georgi:nuclear factor kB(NFKB2,NFKB1),interleukin(IL-6,IL-1B),toll like receptor 4(TLR4),tumor necrosis factor(TNF)and so on are mostly induced by inflammation It is related to body damage.Bupleurum and scutellaria have the clinical effects of anti-inflammatory,antiviral,strengthening immunity,inhibiting pulmonary fibrosis and so on.Conclusion:Radix Bupleuri Scutellariae can be used to treat covid-19 by multi-channel,multi-target and multi ring.The results of this study provide a theoretical basis for Bupleurum Scutellaria to improve the use of COVID-19.

Mechanism for Integrating Sustainability in Engineering Design

This paper proposes an integration mechanism to help the owners and designers to integrate sustainability issues into design process, communicate with stakeholders and achieve consensus. Literature concerning engineering design, decision making and environment assessment were reviewed. Sustainability disputes in construction projects were analyzed and owners and designers were interviewed to understand the evolvement of these issues. Key success factors of other successful integration projects were also referenced. An integration mechanism including procedures was established along with traditional design process. Four integration steps were developed： organize integration team, propose integration issues, determine acceptance criteria, and evaluate alternatives; and four integration dimensions were also identified： appeals, decision making and execution, stakeholders, and experts. A matrix was formed by the four integration steps and four dimensions. A rigor index was proposed to measure the quality of the integration process. Finally, the mechanism was tested on a construction project with sustainability controversy to check its validity. The study results show that the integration mechanism can help incorporate sustainability issues and achieve consensus if followed rigorously. The integration matrix systematically examines the eight key integration factors under the four dimensions. The rigor index can explain the quality in integrating sustainability issues into engineering design. The mechanism provides a useful tool for the owners and designers to cope with the sustainability decision making difficulties.

Prediction of the mechanism of prostate prescription Ⅰ in the treatment of chronic prostatitis based on integrative pharmacology of traditional Chinese medicine

Objective:To investigate potential mechanism of Prostate prescriptionⅠin the treatment of chronic prostatitis based on integrated pharmacology.Methods:with the help of TCMIP,the effective compounds of Prostate prescriptionⅠwere screened,and the potential target database of Prostate prescriptionⅠwas established by using the target prediction function of TCMIP.Based on the Human Phenotype Ontology database and protein interaction network(PPI)database,the disease target of CP was identified and the target interaction network was constructed;Through the GO function analysis and KEGG pathway enrichment analysis of the candidate targets,combined with Chinese and foreign literature studies to predict the potential Signaling pathway of Prostate prescriptionⅠin the treatment of CP.Results:79 effective compounds of Prostate prescriptionⅠexerted its effect on 33 targets through 11 pathways.Conclusion:Clinical efficacy of Prostate prescriptionⅠon CP may be reflected in antiinflammation and anti-tumor,cell metabolism,immune regulation,neuroregulation and so on.

Research and Review on the Development of Mechanical and Electrical Integration of System Function Principle and Related Technologies

In this paper, we conduct research on the development of mechanical and electrical integration of system function principle and related technologies. Along with the rapid and continuous development of modem science and technology, it ＇ s for the penetration and cross of different subjects great push, the more important is caused by technological revolution in the field of engineering and mechanical engineering field under the rapid development of computer technology and microelectronic technology and penetration to the mechanical and electrical integration, which is formed by the mechanical industry lead to trigger a particularly large changes in the mechanical industry management system and mode of production, product and technical structure, composition and function, thus result in industrial production from the previous mechanical electrification progressively electromechanical integration which lead the trend of the current technology.

Exploration of the molecular mechanism of Indigo Naturalis in the treatment of myelodysplastic syndromes through integrated pharmacological study

Background:Oral administration of indigo naturalis(IN)is used as a complementary and alternative medicine(CAM)regimen for the treatment of myelodysplastic syndromes(MDS).However,its mechanism of action has not been fully elucidated and needs to be further explored.Methods:By searching the traditional Chinese medicine system and analyzing platforms(TCMSP),bioinformatics analysis tool for the molecular mechanism of traditional Chinese medicine(BATMAN-TCM),and Swiss Target Prediction network database,the main active components and potential targets of IN were obtained.Based on this,a component-target network was established by Cytoscape 3.6.1 software.Differentially expressed genes(DGEs)in MDS were obtained from three GEO(Gene Expression Omnibus)gene chips.Then,the protein-protein interaction(PPI)network of DGEs was constructed and analyzed by STRING database and Cytoscape 3.6.1 software.In addition,Gene Ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)biological enrichment analysis were carried out using REVIGO and KEGG Orthology Based Annotation System(KOBAS)on DGEs,respectively.Identification of IN-MDS compound targets was performed by matching potential targets of active components with disease-related targets.The results of KEGG pathway enrichment analysis were combined with compound targets to screen key targets.In the end,molecular docking was performed by SYBYL-X2.1 to verify the key targets.Results:Nine active components of IN and 439 potential targets of IN were identified by analyzing TCMSP,BATMAN-TCM,and Swiss Target Prediction network databases.Three MDS disease-related gene microarray chips were obtained from the GEO databases:GSE4619,GSE19429,and GSE58831.Through this analysis,87 DEGs were finally obtained using the Venn diagram.A PPI network of DEGs was then constructed,in which 18 genes were upregulated and 69 genes were downregulated.After the GO enrichment results were de-redundant,the representative GO terms were obtained by using REVIGO semantic similarity measuremen.The KEGG biological pathway analysis using the KOBAS indicated that the Hippo signaling pathway is important in MDS.The Hippo signaling pathway involves four genes:AREG,LEF1,SMAD7,and TCF4.By matching and mapping DEGs with potential targets,six IN-MDS compound targets were obtained:PDE4B,PLAUR,ELANE,NR3C1,AREG,and LEF1.We found that AREG and LEF1 are consistent with the genes involved in the Hippo signaling pathway.Through molecular docking simulation,we found that the indican binds best to AREG and LEF1.Conclusion:Based on the integrated pharmacology model,the material basis of the efficacy and biological molecular mechanism of IN in the treatment of MDS was systematically studied,which provided a novel indication of the CAM regimen for the improvement of MDS management.

基于Mechanism/Pro的汽车悬架系统运动仿真

为了解决多体动力学分析仿真过程中困扰仿真人员的模型建立和修改问题,以汽车独立悬架为研究对象,提出机械系统仿真一种比较理想的方法。首先应用多体动力学求解理论,从悬架物理模型中提取多体动力学求解模型,针对ADAMS/View建模能力较弱,通过三维建模软件Pro/E建模,采用Mechanism/Pro模块定义刚体、添加约束和驱动、调用ADAMS/Sol-ver求解。可以很方便地建立复杂机械系统模型,并根据仿真结果及时对模型进行修改,实现机械系统多体动力学仿真的前处理、求解以及后处理均集成在Pro/E环境中。

INTEGRATED ANALYSIS APPROACHES TO ROCK MECHANICS PROBLEMS

In order to effectively cope with exponent increase of the complexity faced to the rock mechanics analysis problems and the large incompatibility existing between the information level required to model the rock mass and engineering and our obtainable information level at hand,the integrated approaches with intelligent characters are proposed. Many previous standard methods,such as precedent type analysis,rock classification,analytic method stress-based,basic numerical methods (BEM,FEM,DEM,hybrid),and their extended numerical methods (fully coupled) to be developed,can be selected respectively or integrated accordingly. It is alternative to develop basic/fully integrated system,and internet-based approaches. These novel methods can also be selected or integrated each other or with the standard methods to perform rock mechanics analysis. Some key techniques to develop these alternative methods are discussed. It may focus in future on developing fully integrated systems and internet-based approaches. Developing an environmental,virtual facility/space shall be firstly done for this collaborative research on internet.

The Most Probable Mechanism Function and Kinetic Parameters of Gibbsite Dissolution in NaOH

Determination of probable mechanism function and kinetic parameters is important to hydrometallurgical kinetics.In this work,the most probable mechanism function and kinetic parameters of gibbsite dissolution in NaOH solution are studied.The sample,the mixture of synthetic gibbsite and sodium hydroxide solution,was scanned in high-pressure differential scanning calorimetry(DSC) equipment with the heating rate of 10 K·min-1. Integral equation and differential equation of non-isothermal kinetics were solved to fit the data related to DSC curve.According to the calculation results,the most probable mechanism function for pure synthetic gibbsite dissolution in sodium hydroxide solution is presented based on the optimum procedure in the database of the mechanism function.The apparent activation energy obtained is(75±1) kJ·mol-1,the frequency factor is 10 8±1mol·s-1,and the reaction is a second order reaction.

Corrosion behavior of Mg-Zn-Zr-RE alloys under physiological environment-Impact on mechanical integrity and biocompatibility

Benefits of RE addition on Mg alloys strength and corrosion resistance are widely reported but their effects on biodegradability and biocompatibility are still of concern.This paper investigates the effect of RE additions on biodegradability of Mg-Zn alloys under simulated physiological conditions.In this context,two commercial Mg-Zn-Zr-RE alloys,namely ZE41 and EZ33,with same RE addition but different concentrations are studied in Hank’s Balanced Salt Solution(HBSS)at 37℃and with pH of 7.4.Weight-loss,hydrogen evolution,real-time insitu drop test,electrochemical impedance spectroscopy(EIS)and potentiodynamic polarization are deployed to study corrosion characteristics.The mechanical integrity of both alloys is assessed by mechanical testing post immersion.Furthermore,in vitro biocompatibility is evaluated by indirect cytotoxicity tests using NIH3T3 cells.Results reveal that although both alloys showed similar microstructure,size and distribution of precipitates played a significant role on its corrosion response.EIS and open circuit potential results show stable film formation on EZ33,while ZE41 showed passive layer formation followed by its deterioration,over the analyzed time period.Using real-time drop test,it was shown in ZE41 alloy that both T-phase and Zr-rich precipitates acted as micro cathodes,resulting in an unstable surface film.In EZ33,Zr-rich regions did not influence corrosion response,resulting in better corrosion resistance that was corroborated by post-immersion surface morphology investigations.The higher degradation observed in ZE41 alloy resulted in higher drop in flexural and tensile strength compared to EZ33 alloy.In addition,cytotoxicity tests on NIH3T3 cells revealed that cell viability of EZ33 increased with increasing incubation time,contrary to ZE41,owing to its lower biodegradation behavior and despite higher concentrations of REs.Present results show that an increase in RE concentration in EZ33,relative to ZE41,had a positive effect on corrosion rate that subsequently controlled alloy mechanical integrity and biocompatibility.

Integrating Factors and Conservation Laws for Relativistic Mechanical System

In this paper, we present a new method to construct the conservation laws for relativistic mechanical systems by finding corresponding integrating factors. First, the Lagrange equations of relativistic mechanical systems are established, and the definition of integrating factors of the systems is given; second, the necessary conditions for the existence of conserved quantities of the relativistic mechanical systems are studied in detail, and the relation between the conservation laws and the integrating factors of the systems is obtained and the generalized Killing equations for the determination of the integrating factors are given; finally, the conservation theorem and its inverse for the systems are established, and an example is given to illustrate the application of the results.

Design of a Mobile Mechanism for Missing Miner Search Robots in Underground Mines

A mobile mechanism with four tracked-units for a missing miner search robot (MMSR) is presented, with a design based on the terrain features and atrocious environment of an underground mine. Its structure and working prin- ciple is discussed. The four tracked-units are controlled independently and driven cooperatively. By means of two DC motors being controlled respectively, one tracked-unit can accomplish two types of driving mode: tracked travel and in- tegral unit legged rotation (IULR), forming a track-legged compound function mechanism. Its capabilities of surmount- ing obstacles and its toppling stability in underground mines have also been analyzed. The results show that the mobile mechanism can directly surmount an obstacle of the height less than the length of one tracked-unit and get across a raceway with a span less than the length of one tracked-unit by using tracked travel and IULR. Its unstable slope angle is 51.3°. Toppling stability is determined by its structural size, moving direction and slope angle. IULR of four tracked-units can adjust the robot’s posture and then enhance toppling stability or assist in surmounting obstacles. Its track-legged compound function mechanism makes it suitable for working in underground mines.