An E//B neutral particle analyzer(NPA)has been designed and is under development at Sichuan University and Southwestern Institute of Physics.The main purpose of the E//B NPA is to measure the distribution function of ...An E//B neutral particle analyzer(NPA)has been designed and is under development at Sichuan University and Southwestern Institute of Physics.The main purpose of the E//B NPA is to measure the distribution function of fast ions in the HL-2A/3 tokamak.The E//B NPA contains three main units,i.e.the stripping unit,the analyzing unit and the detection unit.A gas stripping chamber was adopted as the stripping unit.The results of the simulations and beam tests for the stripping chamber are presented.Parallel electric and magnetic fields provided by a NdFeB permanent magnet and two parallel electric plates were designed and constructed for the analyzing unit.The calibration of the magnetic and electric fields was performed using a 50 kV electron cyclotron resonance ion source(ECRIS)platform.The detection unit consists of 32lutetium-yttrium oxyorthosilicate(LYSO)detector modules arranged in two rows.The response functions ofα,hydrogen ions(H^(+),H_(2)^(+)and H_(3)^(+))andγfor a detector module were measured with^(241)Am,^(137)Cs and^(152)Eu sources together with the 50 kV ECRIS platform.The overall results indicate that the designed E//B NPA device is capable of measuring the intensity of neutral hydrogen and deuteron atoms with energy higher than 20 keV.展开更多
AIM:To invastigate intra-and interobserver reliability of interferometry,tear meniscus height(TMH)measurement and meibography(MBG)of an ocular surface analyzer,LacryDiag(Quantel Medical,France).METHODS:Five consecutiv...AIM:To invastigate intra-and interobserver reliability of interferometry,tear meniscus height(TMH)measurement and meibography(MBG)of an ocular surface analyzer,LacryDiag(Quantel Medical,France).METHODS:Five consecutive measurements and subsequent analysis of interferometry,TMH,and MBG were recorded by two examiners using the LacryDiag.To assess intra-and interobserver reliability,we used Cohen’s kappa for categorical variables(interferometry),or intraclass correlation coefficient for continuous variables(TMH,MBG).RESULTS:Thirty eyes of 30 examinees were included.For both observers,there was excellent intraobserver reliability for MBG(0.955 and 0.970 for observer 1 and 2,respectively).Intraobserver reliability for observer 1 was substantial for interferometry(0.799),and excellent for TMH(0.863).Reliability for observer 2 was moderate for interferometry(0.535)and fair to good for TMH(0.431).Interobserver reliability was poor for interferometry(0.074)and fair to good for TMH(0.680)and MBG(0.414).CONCLUSION:LacryDiag ocular surface analyzer in our study proves to be a reliable noninvasive tool for the evaluation of TMH and MBG.As for interferometry,poor interobserver reliability,fair to good intraobserver reliability for observer 1,and moderate for observer 2,leave room for improvement.展开更多
In this study,a wavelet multi-resolution interpolation Galerkin method(WMIGM)is proposed to solve linear singularly perturbed boundary value problems.Unlike conventional wavelet schemes,the proposed algorithm can be r...In this study,a wavelet multi-resolution interpolation Galerkin method(WMIGM)is proposed to solve linear singularly perturbed boundary value problems.Unlike conventional wavelet schemes,the proposed algorithm can be readily extended to special node generation techniques,such as the Shishkin node.Such a wavelet method allows a high degree of local refinement of the nodal distribution to efficiently capture localized steep gradients.All the shape functions possess the Kronecker delta property,making the imposition of boundary conditions as easy as that in the finite element method.Four numerical examples are studied to demonstrate the validity and accuracy of the proposedwavelet method.The results showthat the use ofmodified Shishkin nodes can significantly reduce numerical oscillation near the boundary layer.Compared with many other methods,the proposed method possesses satisfactory accuracy and efficiency.The theoretical and numerical results demonstrate that the order of theε-uniform convergence of this wavelet method can reach 5.展开更多
To verify the effectiveness of digital optical 3D image analyzer EvaSKIN in the objective and quantitative evaluation of wrinkles.A total of 115 subjects were recruited,the facial images of the subjects were collected...To verify the effectiveness of digital optical 3D image analyzer EvaSKIN in the objective and quantitative evaluation of wrinkles.A total of 115 subjects were recruited,the facial images of the subjects were collected by digital optical 3D image analyzer and manual camera,the changes of crow’s feet with age were analyzed.Pictures obtained by manual photography can be directly used for observation and preliminary grading of wrinkles.However,the requirements for evaluators are high,and the results are prone to errors,which will affect the accuracy of the evaluation.Therefore,skilled raters are needed.Compared with the manual photography method,the digital optical 3D image analyzer EvaSKIN can realize three-dimensional extraction of wrinkles,and obtain the change trend of crow’s feet with age.20~30 years old,wrinkles begin to appear slowly;wrinkles will increase rapidly at the age of 30~50;The length of 50~60 year old wrinkles is basically fixed,the wrinkles develop longitudewise,gradually widen and deepen,and the area,depth and volume increase is obvious,and the skin aging condition is intensified.the digital optical 3D image analyzer EvaSKIN realizes the 3D extraction of wrinkles,quantifies the circumference,area,average depth,maximum depth and volume of wrinkles,realizes the objective and quantitative evaluation of wrinkle state,is more accurate in the measurement of wrinkles,and provides a new instrument and method for the evaluation of wrinkles.it is a perfect and supplement to the traditional evaluation methods,and to a certain extent,it helps the research and development and evaluation institutions of cosmetics to obtain more abundant and three-dimensional data support.展开更多
Objective:To investigate the hook effect in the detection of beta2-microglobulin(β2-MG)with different reagents as well as on two fully automated biochemical analyzers and their solutions.Methods:Using immunoturbidime...Objective:To investigate the hook effect in the detection of beta2-microglobulin(β2-MG)with different reagents as well as on two fully automated biochemical analyzers and their solutions.Methods:Using immunoturbidimetric assay forβ2-MG as the research object,β2-MG levels were detected by different concentration gradients ofβ2-microglobulin samples in Liedemann,Mack,and Myriad reagents of three manufacturers on two automatic biochemical analyzers,and the difference of the hook effect was comparatively analyzed.Results:Leadman reagent showed the hook effect on the Beckman AU5800 automated biochemistry analyzer,while both Maccura and Mindray reagents did not show the hook effect.After the experiments,we found the limit value of the pre-zone check of Leadman reagent,and changed the parameters of the instrument,when the limit value of the pre-zone check was reached,the instrument automatically diluted the specimen five times and then detected it again.After changing the parameters of the instrument,the correlation between the three methods of detecting samples of different concentrations was r>0.99.Conclusion:Before selecting the application of immunoturbidimetric reagents,we have to carry out the risk assessment of the hook effect and selectively set the parameters of the pre-zone check based on the highest concentration that may occur in the clinic;for the items that may have the hook effect,we have to selectively set the parameters of the pre-zone check when the ratio of average reaction rate and the immediate reaction rate is at the limit value,and the phenomenon of antigen excess may occur,the instrument will carry out automatic dilution before detection,so as to avoid the issuance of erroneous results of high-value samples due to the hook effect.展开更多
In this study, nine high-lysine maize kernels and two kernels of common maize hybrid were used as experiment materials, and quantitative determination of lysine contents in high-lysine maize kernels and common maize k...In this study, nine high-lysine maize kernels and two kernels of common maize hybrid were used as experiment materials, and quantitative determination of lysine contents in high-lysine maize kernels and common maize kernels was carried out using Hitachi L-8900 Automatic Amino-acid Analyzer, to know the effect of the Analyzer in distinguishing the lysine contents between common maize kernels and high-lysine maize kernels. The results showed that the lysine contents of high-lysine maize kernels were among 0.34%-0.42%, while of common maize kernels were a- mong 0.24%-0.25%, and the difference was significant. Compared with other tradi- tional methods, this method is rapid, simple, sensitive, highly reproductive and needs fewer maize kernels, thus it is applicable in maize breeding.展开更多
辽宁某公司原凝析油蒸馏装置加工能力10万t/a,2013年将其加工能力改造至22万t/a。装置在改造设计过程中,为降低能耗,对换热网络采用Aspen Energy Analyzer软件进行优化设计,换热网络优化改造后各换热单元冷端温差均大于夹点温差20℃,热...辽宁某公司原凝析油蒸馏装置加工能力10万t/a,2013年将其加工能力改造至22万t/a。装置在改造设计过程中,为降低能耗,对换热网络采用Aspen Energy Analyzer软件进行优化设计,换热网络优化改造后各换热单元冷端温差均大于夹点温差20℃,热负荷均大于4.186 8×105k J/h;投资费有所降低,虽然改造后加热负荷和冷却负荷均有所增加,但换热网络符合能量松弛的原则,总体上,凝析油蒸馏装置的换热网络得到了优化,满足了换热网络投资费用和操作费用最小的要求。展开更多
Walt·Whitman was one of the famous poets in American literary field. He is remembered by his masterpiece-Leaves of Grass, which composes a lot of his democratic ideas. His democratic poems and his writing styles ...Walt·Whitman was one of the famous poets in American literary field. He is remembered by his masterpiece-Leaves of Grass, which composes a lot of his democratic ideas. His democratic poems and his writing styles have their historical background which helped form his democratic ideas.展开更多
Given the infinite expansion of Machine Empire,what kind of future will appear between human and robot? The most creative aspect of Double xposure is the thinking dimension of human-robot ethics which was brought by t...Given the infinite expansion of Machine Empire,what kind of future will appear between human and robot? The most creative aspect of Double xposure is the thinking dimension of human-robot ethics which was brought by the rise of Robot Empire.展开更多
火炬气的排放系统设计是一个非常复杂的过程,涉及到各泄放点的背压与管路马赫数的计算。介绍了Aspen Flare System Analyzer模拟软件的特点及应用方法,该软件遵循API的规范要求,通过计算火炬管网中各管段始末点的压力、温度、流速等参数...火炬气的排放系统设计是一个非常复杂的过程,涉及到各泄放点的背压与管路马赫数的计算。介绍了Aspen Flare System Analyzer模拟软件的特点及应用方法,该软件遵循API的规范要求,通过计算火炬管网中各管段始末点的压力、温度、流速等参数,可有效发现设计中的不合理管径并进行修改。以中东某油田地面工程项目为例,阐述了在工程实际中如何通过该软件进行火炬管网核算。高压火炬管网的核算结果显示,部分安全阀尾管背压和马赫数过大,经软件修改后的尺寸在实际运行中可满足火炬气的排放要求,保证了系统安全。表明了该软件在安全阀的选型和火炬管网的设计工作中的应用价值。展开更多
The increasing morbidity of internal diseases poses serious threats to human health and quality of life.Exhaled breath analysis is a noninvasive and convenient diagnostic method to improve the cure rate of patients. I...The increasing morbidity of internal diseases poses serious threats to human health and quality of life.Exhaled breath analysis is a noninvasive and convenient diagnostic method to improve the cure rate of patients. In this study, a self-powered breath analyzer based on polyaniline/polyvinylidene fluoride(PANI/PVDF) piezogas-sensing arrays has been developed for potential detection of several internal diseases. The device works by converting exhaled breath energy into piezoelectric gassensing signals without any external power sources. The five sensing units in the device have different sensitivities to various gas markers with concentrations ranging from 0 to 600 ppm. The working principle can be attributed to the coupling of the in-pipe gas-flow-induced piezoelectric effect of PVDF and gas-sensing properties of PANI electrodes. In addition, the device demonstrates its use as an ethanol analyzer to roughly mimic fatty liver diagnosis.This new approach can be applied to fabricating new exhaled breath analyzers and promoting the development of self-powered systems.展开更多
基金supported by the National Magnetic Confinement Fusion Energy R&D Program of China(No.2018YFE0310200)National Natural Science Foundation of China(Nos.11705242,11805138 and 12175156)the Fundamental Research Funds for the Central Universities in China(Nos.YJ201820 and YJ201954)。
文摘An E//B neutral particle analyzer(NPA)has been designed and is under development at Sichuan University and Southwestern Institute of Physics.The main purpose of the E//B NPA is to measure the distribution function of fast ions in the HL-2A/3 tokamak.The E//B NPA contains three main units,i.e.the stripping unit,the analyzing unit and the detection unit.A gas stripping chamber was adopted as the stripping unit.The results of the simulations and beam tests for the stripping chamber are presented.Parallel electric and magnetic fields provided by a NdFeB permanent magnet and two parallel electric plates were designed and constructed for the analyzing unit.The calibration of the magnetic and electric fields was performed using a 50 kV electron cyclotron resonance ion source(ECRIS)platform.The detection unit consists of 32lutetium-yttrium oxyorthosilicate(LYSO)detector modules arranged in two rows.The response functions ofα,hydrogen ions(H^(+),H_(2)^(+)and H_(3)^(+))andγfor a detector module were measured with^(241)Am,^(137)Cs and^(152)Eu sources together with the 50 kV ECRIS platform.The overall results indicate that the designed E//B NPA device is capable of measuring the intensity of neutral hydrogen and deuteron atoms with energy higher than 20 keV.
文摘AIM:To invastigate intra-and interobserver reliability of interferometry,tear meniscus height(TMH)measurement and meibography(MBG)of an ocular surface analyzer,LacryDiag(Quantel Medical,France).METHODS:Five consecutive measurements and subsequent analysis of interferometry,TMH,and MBG were recorded by two examiners using the LacryDiag.To assess intra-and interobserver reliability,we used Cohen’s kappa for categorical variables(interferometry),or intraclass correlation coefficient for continuous variables(TMH,MBG).RESULTS:Thirty eyes of 30 examinees were included.For both observers,there was excellent intraobserver reliability for MBG(0.955 and 0.970 for observer 1 and 2,respectively).Intraobserver reliability for observer 1 was substantial for interferometry(0.799),and excellent for TMH(0.863).Reliability for observer 2 was moderate for interferometry(0.535)and fair to good for TMH(0.431).Interobserver reliability was poor for interferometry(0.074)and fair to good for TMH(0.680)and MBG(0.414).CONCLUSION:LacryDiag ocular surface analyzer in our study proves to be a reliable noninvasive tool for the evaluation of TMH and MBG.As for interferometry,poor interobserver reliability,fair to good intraobserver reliability for observer 1,and moderate for observer 2,leave room for improvement.
基金supported by the National Natural Science Foundation of China (No.12172154)the 111 Project (No.B14044)+1 种基金the Natural Science Foundation of Gansu Province (No.23JRRA1035)the Natural Science Foundation of Anhui University of Finance and Economics (No.ACKYC20043).
文摘In this study,a wavelet multi-resolution interpolation Galerkin method(WMIGM)is proposed to solve linear singularly perturbed boundary value problems.Unlike conventional wavelet schemes,the proposed algorithm can be readily extended to special node generation techniques,such as the Shishkin node.Such a wavelet method allows a high degree of local refinement of the nodal distribution to efficiently capture localized steep gradients.All the shape functions possess the Kronecker delta property,making the imposition of boundary conditions as easy as that in the finite element method.Four numerical examples are studied to demonstrate the validity and accuracy of the proposedwavelet method.The results showthat the use ofmodified Shishkin nodes can significantly reduce numerical oscillation near the boundary layer.Compared with many other methods,the proposed method possesses satisfactory accuracy and efficiency.The theoretical and numerical results demonstrate that the order of theε-uniform convergence of this wavelet method can reach 5.
文摘To verify the effectiveness of digital optical 3D image analyzer EvaSKIN in the objective and quantitative evaluation of wrinkles.A total of 115 subjects were recruited,the facial images of the subjects were collected by digital optical 3D image analyzer and manual camera,the changes of crow’s feet with age were analyzed.Pictures obtained by manual photography can be directly used for observation and preliminary grading of wrinkles.However,the requirements for evaluators are high,and the results are prone to errors,which will affect the accuracy of the evaluation.Therefore,skilled raters are needed.Compared with the manual photography method,the digital optical 3D image analyzer EvaSKIN can realize three-dimensional extraction of wrinkles,and obtain the change trend of crow’s feet with age.20~30 years old,wrinkles begin to appear slowly;wrinkles will increase rapidly at the age of 30~50;The length of 50~60 year old wrinkles is basically fixed,the wrinkles develop longitudewise,gradually widen and deepen,and the area,depth and volume increase is obvious,and the skin aging condition is intensified.the digital optical 3D image analyzer EvaSKIN realizes the 3D extraction of wrinkles,quantifies the circumference,area,average depth,maximum depth and volume of wrinkles,realizes the objective and quantitative evaluation of wrinkle state,is more accurate in the measurement of wrinkles,and provides a new instrument and method for the evaluation of wrinkles.it is a perfect and supplement to the traditional evaluation methods,and to a certain extent,it helps the research and development and evaluation institutions of cosmetics to obtain more abundant and three-dimensional data support.
基金Baoding Science and Technology Bureau(2141ZF313)。
文摘Objective:To investigate the hook effect in the detection of beta2-microglobulin(β2-MG)with different reagents as well as on two fully automated biochemical analyzers and their solutions.Methods:Using immunoturbidimetric assay forβ2-MG as the research object,β2-MG levels were detected by different concentration gradients ofβ2-microglobulin samples in Liedemann,Mack,and Myriad reagents of three manufacturers on two automatic biochemical analyzers,and the difference of the hook effect was comparatively analyzed.Results:Leadman reagent showed the hook effect on the Beckman AU5800 automated biochemistry analyzer,while both Maccura and Mindray reagents did not show the hook effect.After the experiments,we found the limit value of the pre-zone check of Leadman reagent,and changed the parameters of the instrument,when the limit value of the pre-zone check was reached,the instrument automatically diluted the specimen five times and then detected it again.After changing the parameters of the instrument,the correlation between the three methods of detecting samples of different concentrations was r>0.99.Conclusion:Before selecting the application of immunoturbidimetric reagents,we have to carry out the risk assessment of the hook effect and selectively set the parameters of the pre-zone check based on the highest concentration that may occur in the clinic;for the items that may have the hook effect,we have to selectively set the parameters of the pre-zone check when the ratio of average reaction rate and the immediate reaction rate is at the limit value,and the phenomenon of antigen excess may occur,the instrument will carry out automatic dilution before detection,so as to avoid the issuance of erroneous results of high-value samples due to the hook effect.
基金Supported by Henan Major Scientific and Technological Project(121100110300)Outstanding Youth Project of Henan Academy of Agricultural Sciences(2013YQ006)~~
文摘In this study, nine high-lysine maize kernels and two kernels of common maize hybrid were used as experiment materials, and quantitative determination of lysine contents in high-lysine maize kernels and common maize kernels was carried out using Hitachi L-8900 Automatic Amino-acid Analyzer, to know the effect of the Analyzer in distinguishing the lysine contents between common maize kernels and high-lysine maize kernels. The results showed that the lysine contents of high-lysine maize kernels were among 0.34%-0.42%, while of common maize kernels were a- mong 0.24%-0.25%, and the difference was significant. Compared with other tradi- tional methods, this method is rapid, simple, sensitive, highly reproductive and needs fewer maize kernels, thus it is applicable in maize breeding.
文摘辽宁某公司原凝析油蒸馏装置加工能力10万t/a,2013年将其加工能力改造至22万t/a。装置在改造设计过程中,为降低能耗,对换热网络采用Aspen Energy Analyzer软件进行优化设计,换热网络优化改造后各换热单元冷端温差均大于夹点温差20℃,热负荷均大于4.186 8×105k J/h;投资费有所降低,虽然改造后加热负荷和冷却负荷均有所增加,但换热网络符合能量松弛的原则,总体上,凝析油蒸馏装置的换热网络得到了优化,满足了换热网络投资费用和操作费用最小的要求。
文摘Walt·Whitman was one of the famous poets in American literary field. He is remembered by his masterpiece-Leaves of Grass, which composes a lot of his democratic ideas. His democratic poems and his writing styles have their historical background which helped form his democratic ideas.
文摘Given the infinite expansion of Machine Empire,what kind of future will appear between human and robot? The most creative aspect of Double xposure is the thinking dimension of human-robot ethics which was brought by the rise of Robot Empire.
文摘火炬气的排放系统设计是一个非常复杂的过程,涉及到各泄放点的背压与管路马赫数的计算。介绍了Aspen Flare System Analyzer模拟软件的特点及应用方法,该软件遵循API的规范要求,通过计算火炬管网中各管段始末点的压力、温度、流速等参数,可有效发现设计中的不合理管径并进行修改。以中东某油田地面工程项目为例,阐述了在工程实际中如何通过该软件进行火炬管网核算。高压火炬管网的核算结果显示,部分安全阀尾管背压和马赫数过大,经软件修改后的尺寸在实际运行中可满足火炬气的排放要求,保证了系统安全。表明了该软件在安全阀的选型和火炬管网的设计工作中的应用价值。
基金supported by the National Natural Science Foundation of China (11674048)the Fundamental Research Funds for the Central Universities (N170505001 and N160502002)Program for Shenyang Youth Science and Technology Innovation Talents (RC170269)
文摘The increasing morbidity of internal diseases poses serious threats to human health and quality of life.Exhaled breath analysis is a noninvasive and convenient diagnostic method to improve the cure rate of patients. In this study, a self-powered breath analyzer based on polyaniline/polyvinylidene fluoride(PANI/PVDF) piezogas-sensing arrays has been developed for potential detection of several internal diseases. The device works by converting exhaled breath energy into piezoelectric gassensing signals without any external power sources. The five sensing units in the device have different sensitivities to various gas markers with concentrations ranging from 0 to 600 ppm. The working principle can be attributed to the coupling of the in-pipe gas-flow-induced piezoelectric effect of PVDF and gas-sensing properties of PANI electrodes. In addition, the device demonstrates its use as an ethanol analyzer to roughly mimic fatty liver diagnosis.This new approach can be applied to fabricating new exhaled breath analyzers and promoting the development of self-powered systems.
