Soil liquefaction is one of the complex research topics in geotechnical engineering and engineering geology. Especially after the 1964 Niigata earthquake (Japan) induced many soil liquefaction incidents, a variety of ...Soil liquefaction is one of the complex research topics in geotechnical engineering and engineering geology. Especially after the 1964 Niigata earthquake (Japan) induced many soil liquefaction incidents, a variety of soil liquefaction studies were conducted and reported, including the liquefaction potential assessment methods utilizing the shear wave velocity (V<sub>s</sub>) or SPT-N profiles (SPT: standard penetration test). This study used the V<sub>s</sub> and SPT methods recommended by the National Center for Earthquake Engineering Research (NCEER) to examine which is more conservative according to the assessment results on 41 liquefiable soil layers at sites in two major cities in Taiwan. Statistical hypothesis testing was used to make the analysis more quantitative and objective. Based on three sets of hypothesis tests, it shows that the hypothesis—the SPT method is more conservative than the V<sub>s</sub> method—was not rejected on a 5% level of significance.展开更多
Eliminating the false intersection (deghosting) is a difficult problem in a passive cross location system. Using a decentralized decision fusion topology, a new deghosting algorithm derived from hypothesis testing the...Eliminating the false intersection (deghosting) is a difficult problem in a passive cross location system. Using a decentralized decision fusion topology, a new deghosting algorithm derived from hypothesis testing theory is developed. It uses the difference between ghosts and true targets in the statistical error, which occurs between their projection angles on a deghosting sensor and is measured from a deghosting sensor, and constructs a corresponding test statistic. Under the Gaussian assumption, ghosts and true targets are decided and discriminated by Chi-square distribution. Simulation results show the feasibility of the algorithm.展开更多
Introduction: This work investigates whether to conduct a medical study from the point of view of the expected net benefit taking into account statistical power, time and cost. The hypothesis of this paper is that the...Introduction: This work investigates whether to conduct a medical study from the point of view of the expected net benefit taking into account statistical power, time and cost. The hypothesis of this paper is that the expected net benefit is equal to zero. Methods: Information were obtained from a pilot medical study that investigates the effects of two diagnostic modalities, magnetic resonance imaging (MRI) and computerized axial tomography scanner (CT), on patients with acute stroke. Statistical procedure was applied for planning and contrasting equivalence, non-inferiority and inequality hypotheses of the study for the effectiveness, health benefits and costs. A statistical simulation model was applied to test the hypothesis that conducting the study would or not result in overall net benefits. If the null hypothesis not rejected, no benefits would occurred and therefore the two arms-patterns of diagnostic and treatment are of equal net benefits. If the null hypothesis is rejected, net benefits would occur if patients are diagnosed with the more favourable diagnostic modality. Results: For any hypothesis design, the expected net benefits are in the range of 366 to 1796 per patient at 80% of statistical power if conducting the study. The power depends on the monetary value available for a unit of health improvement. Conclusion: The statistical simulations suggest that diagnosing patients with CT will provide more favourable health outcomes showing statistically significant expected net benefits in comparison with MRI.展开更多
When a statistical test of hypothesis for a population mean is performed, we are faced with the possibility of committing a Type II error by not rejecting the null hypothesis when in fact the population mean has chang...When a statistical test of hypothesis for a population mean is performed, we are faced with the possibility of committing a Type II error by not rejecting the null hypothesis when in fact the population mean has changed. We consider this issue and quantify matters in a manner that differs a bit from what is commonly done. In particular, we define the probability distribution function for Type II errors. We then explore some interesting properties that we have not seen mentioned elsewhere for this probability distribution function. Finally, we discuss several Maple procedures that can be used to perform various calculations using the distribution.展开更多
One of the important fields in statistics is testing hypothesis of correlation coefficient. The extension of the idea of testing correlation to fuzzy hypothesis is of great interesting. In this study, we examined the ...One of the important fields in statistics is testing hypothesis of correlation coefficient. The extension of the idea of testing correlation to fuzzy hypothesis is of great interesting. In this study, we examined the use of fuzzy hypothesis testing approach for the Sequential Probability Ratio Test (SPRT) of correlation coefficient. Use of fuzzy hypothesis testing for correlation coefficient with SPRT is illustrated by an example.展开更多
A novel statistical approach to evaluate the manufacturing quality of press coated tablets in terms of the centering of their core is presented. We also provide a formula to determine the necessary sample size. This a...A novel statistical approach to evaluate the manufacturing quality of press coated tablets in terms of the centering of their core is presented. We also provide a formula to determine the necessary sample size. This approach is applied to real data.展开更多
Schizophrenia(SZ)is one of the most common mental diseases.Its main characteristics are abnormal social behavior and inability to correctly understand real things.In recent years,the magnetic resonance imaging(MRI)tec...Schizophrenia(SZ)is one of the most common mental diseases.Its main characteristics are abnormal social behavior and inability to correctly understand real things.In recent years,the magnetic resonance imaging(MRI)technique has been popularly utilized to study SZ.However,it is still a great challenge to reveal the essential information contained in the MRI data.In this paper,we proposed a biomarker selection approach based on the multiple hypothesis testing techniques to explore the difference between SZ and healthy controls by using both functional and structural MRI data,in which biomarkers represent both abnormal brain functional connectivity and abnormal brain regions.By implementing the biomarker selection approach,six abnormal brain regions and twenty-three abnormal functional connectivity in the brains of SZ are explored.It is discovered that compared with healthy controls,the significantly reduced gray matter volumes are mainly distributed in the limbic lobe and the basal ganglia,and the significantly increased gray matter volumes are distributed in the frontal gyrus.Meanwhile,it is revealed that the significantly strengthened connections are those between the middle frontal gyrus and the superior occipital gyrus,the superior occipital gyrus and the middle occipital gyrus as well as the middle occipital gyrus and the fusiform gyrus,and the rest connections are significantly weakened.展开更多
Testing the equality of percentiles (quantiles) between populations is an effective method for robust, nonparametric comparison, especially when the distributions are asymmetric or irregularly shaped. Unlike global no...Testing the equality of percentiles (quantiles) between populations is an effective method for robust, nonparametric comparison, especially when the distributions are asymmetric or irregularly shaped. Unlike global nonparametric tests for homogeneity such as the Kolmogorv-Smirnov test, testing the equality of a set of percentiles (i.e., a percentile profile) yields an estimate of the location and extent of the differences between the populations along the entire domain. The Wald test using bootstrap estimates of variance of the order statistics provides a unified method for hypothesis testing of functions of the population percentiles. Simulation studies are conducted to show performance of the method under various scenarios and to give suggestions on its use. Several examples are given to illustrate some useful applications to real data.展开更多
The use of Statistical Hypothesis Testing procedure to determine type I and type II errors was linked to the measurement of sensitivity and specificity in clinical trial test and experimental pathogen detection techni...The use of Statistical Hypothesis Testing procedure to determine type I and type II errors was linked to the measurement of sensitivity and specificity in clinical trial test and experimental pathogen detection techniques. A theoretical analysis of establishing these types of errors was made and compared to determination of False Positive, False Negative, True Positive and True Negative. Experimental laboratory detection methods used to detect Cryptosporidium spp. were used to highlight the relationship between hypothesis testing, sensitivity, specificity and predicted values. The study finds that, sensitivity and specificity for the two laboratory methods used for Cryptosporidium detection were low hence lowering the probability of detecting a “false null hypothesis” for the presence of cryptosporidium in the water samples using either Microscopic or PCR. Nevertheless, both procedures for cryptosporidium detection had higher “true negatives” increasing its probability of failing to reject a “true null hypothesis” with specificity of 1.00 for both Microscopic and PCR laboratory detection methods.展开更多
This paper demonstrates two versions of Whorf hypothesis by giving a conclusion of its commonality and differences. Besides, some classical experiments of testing the hypothesis are given and the author constructs an ...This paper demonstrates two versions of Whorf hypothesis by giving a conclusion of its commonality and differences. Besides, some classical experiments of testing the hypothesis are given and the author constructs an experimental model of testing the weak version of the hypothesis under the instruction of Carroll's three thinking.展开更多
Exclusive hypothesis testing is a new and special class of hypothesis testing.This kind of testing can be applied in survival analysis to understand the association between genomics information and clinical informatio...Exclusive hypothesis testing is a new and special class of hypothesis testing.This kind of testing can be applied in survival analysis to understand the association between genomics information and clinical information about the survival time.Besides,it is well known that Cox's proportional hazards model is the most commonly used model for regression analysis of failure time.In this paper,the authors consider doing the exclusive hypothesis testing for Cox's proportional hazards model with right-censored data.The authors propose the comprehensive test statistics to make decision,and show that the corresponding decision rule can control the asymptotic TypeⅠerrors and have good powers in theory.The numerical studies indicate that the proposed approach works well for practical situations and it is applied to a set of real data arising from Rotterdam Breast Cancer Data study that motivated this study.展开更多
The compensation hypothesis predicts that if the left testis is defective e.g.due to developmental stress,the increased right testis serves a compensatory role,and thereby displaying testes asymmetry which can be a re...The compensation hypothesis predicts that if the left testis is defective e.g.due to developmental stress,the increased right testis serves a compensatory role,and thereby displaying testes asymmetry which can be a reliable indicator of male body condition.Here,to test the prediction of the compensation hypothesis,we analyzed difference in size between left testis and right testis and the relationship between testes asymmetry and male body condition in the swelled vent frog(Feirana quadranus).We found that the left testis was larger than right testis,displaying a significant directional asymmetry in testes size.Although testes mass was correlated with body condition,testes asymmetry was not correlated with body condition,which cannot provide evidence that the right testis had a compensatory function.Our findings suggest no evidence for the compensation hypothesis in this species due to lacking the compensatory function in right testis.展开更多
Tests for a proportion that may be zero are described. The setting is an environment in which there can be misclassifications or misdiagnoses, giving the possibility of nonzero counts from false positives even though ...Tests for a proportion that may be zero are described. The setting is an environment in which there can be misclassifications or misdiagnoses, giving the possibility of nonzero counts from false positives even though no real examples may exist. Both frequentist and Bayesian tests and analyses are presented, and examples are given.展开更多
Coutsourides derived an ad hoc nuisance paratmeter removal test for testing equality of two multiple correlation matrices of two independent p variate normal populations under the assumption that a sample of size ...Coutsourides derived an ad hoc nuisance paratmeter removal test for testing equality of two multiple correlation matrices of two independent p variate normal populations under the assumption that a sample of size n is available from each population. This paper presents a likelihood ratio test criterion for testing equality of K multiple correlation matrices and extends the results to the testing of equality of K partial correlation matrices.展开更多
In the present study,we undertake the task of hypothesis testing in the context of Poissondistributed data.The primary objective of our investigation is to ascertain whether two distinct sets of discrete data share th...In the present study,we undertake the task of hypothesis testing in the context of Poissondistributed data.The primary objective of our investigation is to ascertain whether two distinct sets of discrete data share the same Poisson rate.We delve into a comprehensive review and comparative analysis of various frequentist and Bayesian methodologies specifically designed to address this problem.Among these are the conditional test,the likelihood ratio test,and the Bayes factor.Additionally,we employ the posterior predictive p-value in our analysis,coupled with its corresponding calibration procedures.As the culmination of our investigation,we apply these diverse methodologies to test both simulated datasets and real-world data.The latter consists of the offspring distributions linked to COVID-19 cases in two disparate geographies-Hong Kong and Rwanda.This allows us to provide a practical demonstration of the methodologies’applications and their potential implications in the field of epidemiology.展开更多
文摘Soil liquefaction is one of the complex research topics in geotechnical engineering and engineering geology. Especially after the 1964 Niigata earthquake (Japan) induced many soil liquefaction incidents, a variety of soil liquefaction studies were conducted and reported, including the liquefaction potential assessment methods utilizing the shear wave velocity (V<sub>s</sub>) or SPT-N profiles (SPT: standard penetration test). This study used the V<sub>s</sub> and SPT methods recommended by the National Center for Earthquake Engineering Research (NCEER) to examine which is more conservative according to the assessment results on 41 liquefiable soil layers at sites in two major cities in Taiwan. Statistical hypothesis testing was used to make the analysis more quantitative and objective. Based on three sets of hypothesis tests, it shows that the hypothesis—the SPT method is more conservative than the V<sub>s</sub> method—was not rejected on a 5% level of significance.
文摘Eliminating the false intersection (deghosting) is a difficult problem in a passive cross location system. Using a decentralized decision fusion topology, a new deghosting algorithm derived from hypothesis testing theory is developed. It uses the difference between ghosts and true targets in the statistical error, which occurs between their projection angles on a deghosting sensor and is measured from a deghosting sensor, and constructs a corresponding test statistic. Under the Gaussian assumption, ghosts and true targets are decided and discriminated by Chi-square distribution. Simulation results show the feasibility of the algorithm.
文摘Introduction: This work investigates whether to conduct a medical study from the point of view of the expected net benefit taking into account statistical power, time and cost. The hypothesis of this paper is that the expected net benefit is equal to zero. Methods: Information were obtained from a pilot medical study that investigates the effects of two diagnostic modalities, magnetic resonance imaging (MRI) and computerized axial tomography scanner (CT), on patients with acute stroke. Statistical procedure was applied for planning and contrasting equivalence, non-inferiority and inequality hypotheses of the study for the effectiveness, health benefits and costs. A statistical simulation model was applied to test the hypothesis that conducting the study would or not result in overall net benefits. If the null hypothesis not rejected, no benefits would occurred and therefore the two arms-patterns of diagnostic and treatment are of equal net benefits. If the null hypothesis is rejected, net benefits would occur if patients are diagnosed with the more favourable diagnostic modality. Results: For any hypothesis design, the expected net benefits are in the range of 366 to 1796 per patient at 80% of statistical power if conducting the study. The power depends on the monetary value available for a unit of health improvement. Conclusion: The statistical simulations suggest that diagnosing patients with CT will provide more favourable health outcomes showing statistically significant expected net benefits in comparison with MRI.
文摘When a statistical test of hypothesis for a population mean is performed, we are faced with the possibility of committing a Type II error by not rejecting the null hypothesis when in fact the population mean has changed. We consider this issue and quantify matters in a manner that differs a bit from what is commonly done. In particular, we define the probability distribution function for Type II errors. We then explore some interesting properties that we have not seen mentioned elsewhere for this probability distribution function. Finally, we discuss several Maple procedures that can be used to perform various calculations using the distribution.
文摘One of the important fields in statistics is testing hypothesis of correlation coefficient. The extension of the idea of testing correlation to fuzzy hypothesis is of great interesting. In this study, we examined the use of fuzzy hypothesis testing approach for the Sequential Probability Ratio Test (SPRT) of correlation coefficient. Use of fuzzy hypothesis testing for correlation coefficient with SPRT is illustrated by an example.
文摘A novel statistical approach to evaluate the manufacturing quality of press coated tablets in terms of the centering of their core is presented. We also provide a formula to determine the necessary sample size. This approach is applied to real data.
基金This work was supported by NSFC(No.11471006 and No.81601456),Science and Technology Innovation Plan of Xi’an(No.2019421315KYPT004JC006)and the HPC Platform,Xi’an Jiaotong University.
文摘Schizophrenia(SZ)is one of the most common mental diseases.Its main characteristics are abnormal social behavior and inability to correctly understand real things.In recent years,the magnetic resonance imaging(MRI)technique has been popularly utilized to study SZ.However,it is still a great challenge to reveal the essential information contained in the MRI data.In this paper,we proposed a biomarker selection approach based on the multiple hypothesis testing techniques to explore the difference between SZ and healthy controls by using both functional and structural MRI data,in which biomarkers represent both abnormal brain functional connectivity and abnormal brain regions.By implementing the biomarker selection approach,six abnormal brain regions and twenty-three abnormal functional connectivity in the brains of SZ are explored.It is discovered that compared with healthy controls,the significantly reduced gray matter volumes are mainly distributed in the limbic lobe and the basal ganglia,and the significantly increased gray matter volumes are distributed in the frontal gyrus.Meanwhile,it is revealed that the significantly strengthened connections are those between the middle frontal gyrus and the superior occipital gyrus,the superior occipital gyrus and the middle occipital gyrus as well as the middle occipital gyrus and the fusiform gyrus,and the rest connections are significantly weakened.
文摘Testing the equality of percentiles (quantiles) between populations is an effective method for robust, nonparametric comparison, especially when the distributions are asymmetric or irregularly shaped. Unlike global nonparametric tests for homogeneity such as the Kolmogorv-Smirnov test, testing the equality of a set of percentiles (i.e., a percentile profile) yields an estimate of the location and extent of the differences between the populations along the entire domain. The Wald test using bootstrap estimates of variance of the order statistics provides a unified method for hypothesis testing of functions of the population percentiles. Simulation studies are conducted to show performance of the method under various scenarios and to give suggestions on its use. Several examples are given to illustrate some useful applications to real data.
文摘The use of Statistical Hypothesis Testing procedure to determine type I and type II errors was linked to the measurement of sensitivity and specificity in clinical trial test and experimental pathogen detection techniques. A theoretical analysis of establishing these types of errors was made and compared to determination of False Positive, False Negative, True Positive and True Negative. Experimental laboratory detection methods used to detect Cryptosporidium spp. were used to highlight the relationship between hypothesis testing, sensitivity, specificity and predicted values. The study finds that, sensitivity and specificity for the two laboratory methods used for Cryptosporidium detection were low hence lowering the probability of detecting a “false null hypothesis” for the presence of cryptosporidium in the water samples using either Microscopic or PCR. Nevertheless, both procedures for cryptosporidium detection had higher “true negatives” increasing its probability of failing to reject a “true null hypothesis” with specificity of 1.00 for both Microscopic and PCR laboratory detection methods.
文摘This paper demonstrates two versions of Whorf hypothesis by giving a conclusion of its commonality and differences. Besides, some classical experiments of testing the hypothesis are given and the author constructs an experimental model of testing the weak version of the hypothesis under the instruction of Carroll's three thinking.
基金supported by the National Natural Science Foundation of China under Grant Nos.11971064,12371262,and 12171374。
文摘Exclusive hypothesis testing is a new and special class of hypothesis testing.This kind of testing can be applied in survival analysis to understand the association between genomics information and clinical information about the survival time.Besides,it is well known that Cox's proportional hazards model is the most commonly used model for regression analysis of failure time.In this paper,the authors consider doing the exclusive hypothesis testing for Cox's proportional hazards model with right-censored data.The authors propose the comprehensive test statistics to make decision,and show that the corresponding decision rule can control the asymptotic TypeⅠerrors and have good powers in theory.The numerical studies indicate that the proposed approach works well for practical situations and it is applied to a set of real data arising from Rotterdam Breast Cancer Data study that motivated this study.
基金the National Natural Sciences Foundation of China(31471996,31772451,31970393)the Key Cultivation Foundation of China West Normal University(17A006)+1 种基金the Science and Technology Youth Innovation Team of Sichuan Province(19CXTD0022)Talent Project of China West Normal University(17YC335)to provide for financial support。
文摘The compensation hypothesis predicts that if the left testis is defective e.g.due to developmental stress,the increased right testis serves a compensatory role,and thereby displaying testes asymmetry which can be a reliable indicator of male body condition.Here,to test the prediction of the compensation hypothesis,we analyzed difference in size between left testis and right testis and the relationship between testes asymmetry and male body condition in the swelled vent frog(Feirana quadranus).We found that the left testis was larger than right testis,displaying a significant directional asymmetry in testes size.Although testes mass was correlated with body condition,testes asymmetry was not correlated with body condition,which cannot provide evidence that the right testis had a compensatory function.Our findings suggest no evidence for the compensation hypothesis in this species due to lacking the compensatory function in right testis.
文摘Tests for a proportion that may be zero are described. The setting is an environment in which there can be misclassifications or misdiagnoses, giving the possibility of nonzero counts from false positives even though no real examples may exist. Both frequentist and Bayesian tests and analyses are presented, and examples are given.
文摘Coutsourides derived an ad hoc nuisance paratmeter removal test for testing equality of two multiple correlation matrices of two independent p variate normal populations under the assumption that a sample of size n is available from each population. This paper presents a likelihood ratio test criterion for testing equality of K multiple correlation matrices and extends the results to the testing of equality of K partial correlation matrices.
基金supported by a grant from City University of Hong Kong (Project No.9610639).
文摘In the present study,we undertake the task of hypothesis testing in the context of Poissondistributed data.The primary objective of our investigation is to ascertain whether two distinct sets of discrete data share the same Poisson rate.We delve into a comprehensive review and comparative analysis of various frequentist and Bayesian methodologies specifically designed to address this problem.Among these are the conditional test,the likelihood ratio test,and the Bayes factor.Additionally,we employ the posterior predictive p-value in our analysis,coupled with its corresponding calibration procedures.As the culmination of our investigation,we apply these diverse methodologies to test both simulated datasets and real-world data.The latter consists of the offspring distributions linked to COVID-19 cases in two disparate geographies-Hong Kong and Rwanda.This allows us to provide a practical demonstration of the methodologies’applications and their potential implications in the field of epidemiology.