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Simultaneous all-solid-state multi-wavelength lasers——a promising pump source for generating highly coherent terahertz waves 被引量:1
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作者 刘欢 徐德刚 姚建铨 《Chinese Physics B》 SCIE EI CAS CSCD 2009年第3期1077-1084,共8页
A diode-end-pumped Nd:YAG dual-wavelength laser operating at 1319 and 1338 nm is demonstrated. The maximum average output power of the quasi-continuous wave linearly polarized dual-wavelength laser is obtained to be ... A diode-end-pumped Nd:YAG dual-wavelength laser operating at 1319 and 1338 nm is demonstrated. The maximum average output power of the quasi-continuous wave linearly polarized dual-wavelength laser is obtained to be 2.1 W at a repetition rate of 50 kHz with an output power instability of less than 0.38% and beam quality factor M^2 of 1.45. Using the two lines, the highly coherent and narrow linewidth terahertz radiation of 3.23 THz can be generated in an organic 4-N, N-dimethylamino-methyl-stilbazolium tosylate (DAST) crystal. Meanwhile, the multi-wavelength red laser at 659.5, 664 and 669 nm is generated by frequency doubling and sum frequency processes in a lithium triborate (LBO) crystal. The average red laser output power is enhanced up to 1.625 W at a repetition rate of 15 kHz with an output power instability of better than 0.53% and beam quality factor M^2 of 6.05. Using the three lines, it is possible to generate the multi-wavelength THz radiation of 3.3, 3.43 and 6.73 THz in an appropriate difference frequency crystal. 展开更多
关键词 end-pumped Nd:YAG laser dual-wavelength laser acousto-optic Q-switch terahertz wave
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Optimizing laser coupling,matter heating,and particle acceleration from solids using multiplexed ultraintense lasers
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作者 Weipeng Yao Motoaki Nakatsutsumi +20 位作者 Sébastien Buffechoux Patrizio Antici Marco Borghesi Andrea Ciardi Sophia N.Chen Emmanuel d’Humières Laurent Gremillet Robert Heathcote Vojtech Horny Paul McKenna Mark N.Quinn Lorenzo Romagnani Ryan Royle Gianluca Sarri Yasuhiko Sentoku Hans-Peter Schlenvoigt Toma Toncian Olivier Tresca Laura Vassura Oswald Willi Julien Fuchs 《Matter and Radiation at Extremes》 SCIE EI CSCD 2024年第4期16-28,共13页
Realizing the full potential of ultrahigh-intensity lasers for particle and radiation generation will require multi-beam arrangements due to technology limitations.Here,we investigate how to optimize their coupling wi... Realizing the full potential of ultrahigh-intensity lasers for particle and radiation generation will require multi-beam arrangements due to technology limitations.Here,we investigate how to optimize their coupling with solid targets.Experimentally,we show that overlapping two intense lasers in a mirror-like configuration onto a solid with a large preplasma can greatly improve the generation of hot electrons at the target front and ion acceleration at the target backside.The underlying mechanisms are analyzed through multidimensional particle-in-cell simulations,revealing that the self-induced magnetic fields driven by the two laser beams at the target front are susceptible to reconnection,which is one possible mechanism to boost electron energization.In addition,the resistive magnetic field generated during the transport of the hot electrons in the target bulk tends to improve their collimation.Our simulations also indicate that such effects can be further enhanced by overlapping more than two laser beams. 展开更多
关键词 laser ACCELERATION PARTICLE
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975 nm multimode semiconductor lasers with high-order Bragg diffraction gratings
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作者 Zhenwu Liu Li Zhong +1 位作者 Suping Liu Xiaoyu Ma 《Journal of Semiconductors》 EI CAS CSCD 2024年第3期38-44,共7页
The 975 nm multimode diode lasers with high-order surface Bragg diffraction gratings have been simulated and calcu-lated using the 2D finite difference time domain(FDTD)algorithm and the scattering matrix method(SMM).... The 975 nm multimode diode lasers with high-order surface Bragg diffraction gratings have been simulated and calcu-lated using the 2D finite difference time domain(FDTD)algorithm and the scattering matrix method(SMM).The periods and etch depth of the grating parameters have been optimized.A board area laser diode(BA-LD)with high-order diffraction grat-ings has been designed and fabricated.At output powers up to 10.5 W,the measured spectral width of full width at half maxi-mum(FWHM)is less than 0.5 nm.The results demonstrate that the designed high-order surface gratings can effectively nar-row the spectral width of multimode semiconductor lasers at high output power. 展开更多
关键词 laser diodes distributed Bragg reflector high order gratings high power laser diodes narrow spectrum width
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Collective coherent emission of electrons in strong laser fields and perspective for hard x-ray lasers
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作者 E.G.Gelfer A.M.Fedotov +1 位作者 O.Klimo S.Weber 《Matter and Radiation at Extremes》 SCIE EI CSCD 2024年第2期1-3,共3页
Coherent motion of particles in a plasma can imprint itself on radiation.The recent advent of high-power lasers—allowing the nonlinear inverse Compton-scattering regime to be reached—has opened the possibility of lo... Coherent motion of particles in a plasma can imprint itself on radiation.The recent advent of high-power lasers—allowing the nonlinear inverse Compton-scattering regime to be reached—has opened the possibility of looking at collective effects in laser–plasma interactions.Under certain conditions,the collective interaction of many electrons with a laser pulse can generate coherent radiation in the hard x-ray regime.This perspective paper explains the limitations under which such a regime might be attained. 展开更多
关键词 laser SCATTERING COHERENT
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On the generation of high-quality Nyquist pulses in mode-locked fiber lasers
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作者 任俞宣 葛锦蔓 +2 位作者 李小军 彭俊松 曾和平 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第3期424-427,共4页
Nyquist pulses have wide applications in many areas,from electronics to optics.Mode-locked lasers are ideal platforms to generate such pulses.However,how to generate high-quality Nyquist pulses in mode-locked lasers r... Nyquist pulses have wide applications in many areas,from electronics to optics.Mode-locked lasers are ideal platforms to generate such pulses.However,how to generate high-quality Nyquist pulses in mode-locked lasers remains elusive.We address this problem by managing different physical effects in mode-locked fiber lasers through extensive numerical simulations.We find that net dispersion,linear loss,gain and filter shaping can affect the quality of Nyquist pulses significantly.We also demonstrate that Nyquist pulses experience similariton shaping due to the nonlinear attractor effect in the gain medium.Our work may contribute to the design of Nyquist pulse sources and enrich the understanding of pulse shaping dynamics in mode-locked lasers. 展开更多
关键词 mode locking laser SOLITON FIBER PULSE
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Gigahertz frequency hopping in an optical phase-locked loop for Raman lasers
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作者 毛德凯 税鸿冕 +3 位作者 殷国玲 彭鹏 王春唯 周小计 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第2期60-65,共6页
Raman lasers are essential in atomic physics,and the development of portable devices has posed requirements for time-division multiplexing of Raman lasers.We demonstrate an innovative gigahertz frequency hopping appro... Raman lasers are essential in atomic physics,and the development of portable devices has posed requirements for time-division multiplexing of Raman lasers.We demonstrate an innovative gigahertz frequency hopping approach of a slave Raman laser within an optical phase-locked loop(OPLL),which finds practical application in an atomic gravimeter,where the OPLL frequently switches between near-resonance lasers and significantly detuned Raman lasers.The method merges the advantages of rapid and extensive frequency hopping with the OPLL’s inherent low phase noise,and exhibits a versatile range of applications in compact laser systems,promising advancements in portable instruments. 展开更多
关键词 Raman lasers optical phase-locked loop frequency hopping
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Phase-locked single-mode terahertz quantum cascade lasers array
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作者 Yunfei Xu Weijiang Li +9 位作者 Yu Ma Quanyong Lu Jinchuan Zhang Shenqiang Zhai Ning Zhuo Junqi Liu Shuman Liu Fengmin Cheng Lijun Wang Fengqi Liu 《Journal of Semiconductors》 EI CAS CSCD 2024年第6期87-91,共5页
We demonstrated a scheme of phase-locked terahertz quantum cascade lasers(THz QCLs)array,with a single-mode pulse power of 108 mW at 13 K.The device utilizes a Talbot cavity to achieve phase locking among five ridge l... We demonstrated a scheme of phase-locked terahertz quantum cascade lasers(THz QCLs)array,with a single-mode pulse power of 108 mW at 13 K.The device utilizes a Talbot cavity to achieve phase locking among five ridge lasers with first-order buried distributed feedback(DFB)grating,resulting in nearly five times amplification of the single-mode power.Due to the optimum length of Talbot cavity depends on wavelength,the combination of Talbot cavity with the DFB grating leads to better power amplification than the combination with multimode Fabry-Perot(F-P)cavities.The Talbot cavity facet reflects light back to the ridge array direction and achieves self-imaging in the array,enabling phase-locked operation of ridges.We set the spacing between adjacent elements to be 220μm,much larger than the free-space wavelength,ensuring the operation of the fundamental supermode throughout the laser's dynamic range and obtaining a high-brightness far-field distribution.This scheme provides a new approach for enhancing the single-mode power of THz QCLs. 展开更多
关键词 quantum cascade lasers phase locking TERAHERTZ single mode
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Generation and regulation of electromagnetic pulses generated by femtosecond lasers interacting with multitargets
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作者 Ya-Dong Xia De-Feng Kong +14 位作者 Qiang-You He Zhen Guo Dong-Jun Zhang Tong Yang Hao Cheng Yu-Ze Li Yang Yan Xiao Liang Ping Zhu Xing-Long Xie Jian-Qiang Zhu Ting-Shuai Li Chen Lin Wen-Jun Ma Xue-Qing Yan 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第1期96-107,共12页
Ultrashort and powerful laser interactions with a target generate intense wideband electromagnetic pulses(EMPs).In this study,we report EMPs generated by the interactions between petawatt(30 fs,1.4×10^(20) W/cm^(... Ultrashort and powerful laser interactions with a target generate intense wideband electromagnetic pulses(EMPs).In this study,we report EMPs generated by the interactions between petawatt(30 fs,1.4×10^(20) W/cm^(2))femtosecond(fs)lasers with metal flat,plastic flat,and plastic nanowire-array(NWA)targets.Detailed analyses are conducted on the EMPs in terms of their spatial distribution,time and frequency domains,radiation energy,and protection.The results indicate that EMPs from metal targets exhibit larger amplitudes at varying angles than those generated by other types of targets and are enhanced significantly for NWA targets.Using a plastic target holder and increasing the laser focal spot can significantly decrease the radiation energy of the EMPs.Moreover,the composite shielding materials indicate an effective shielding effect against EMPs.The simulation results show that the NWA targets exert a collimating effect on thermal electrons,which directly affects the distribution of EMPs.This study provides guidance for regulating EMPs by controlling the laser focal spot,target parameters,and target rod material and is beneficial for electromagnetic-shielding design. 展开更多
关键词 Electromagnetic pulses laser plasma interaction Electromagnetic shielding Electron distribution
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Characteristic analysis of 1.06μm long-cavity diode lasers based on asymmetric waveguide structures
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作者 ZHAO Ren-Ze GAO Xin +3 位作者 FU Ding-Yang ZHANG Yue SU Peng BO Bao-Xue 《红外与毫米波学报》 SCIE EI CAS CSCD 北大核心 2024年第4期557-562,共6页
In long-cavity edge-emitting diode lasers,longitudinal spatial hole burning(LSHB),two-photon ab⁃sorption(TPA)and free carrier absorption(FCA)are among the key factors that affect the linear increase in out⁃put power a... In long-cavity edge-emitting diode lasers,longitudinal spatial hole burning(LSHB),two-photon ab⁃sorption(TPA)and free carrier absorption(FCA)are among the key factors that affect the linear increase in out⁃put power at high injection currents.In this paper,a simplified numerical analysis model is proposed for 1.06μm long-cavity diode lasers by combining TPA and FCA losses with one-dimensional(1D)rate equations.The ef⁃fects of LSHB,TPA and FCA on the output characteristics are systematically analyzed,and it is proposed that ad⁃justing the front facet reflectivity and the position of the quantum well(QW)in the waveguide layer can improve the front facet output power. 展开更多
关键词 diode lasers longitudinal spatial hole burning free carrier absorption two-photon absorption
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Optical facet coatings for high-performance LWIR quantum cascade lasers atλ∼8.5μm
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作者 MA Yuan LIN Yu-Zhe +5 位作者 WAN Chen-Yang WANG Zi-Xian ZHOU Xu-Yan ZHANG Jin-Chuan LIU Feng-Qi ZHENG Wan-Hua 《红外与毫米波学报》 SCIE EI CAS CSCD 北大核心 2024年第4期497-502,共6页
We report on the performance improvement of long-wave infrared quantum cascade lasers(LWIR QCLs)by studying and optimizing the anti-reflection(AR)optical facet coating.Compared to the Al2O3 AR coat⁃ing,the Y_(2)O_(3)A... We report on the performance improvement of long-wave infrared quantum cascade lasers(LWIR QCLs)by studying and optimizing the anti-reflection(AR)optical facet coating.Compared to the Al2O3 AR coat⁃ing,the Y_(2)O_(3)AR coating exhibits higher catastrophic optical mirror damage(COMD)level,and the optical facet coatings of both material systems have no beam steering effect.A 3-mm-long,9.5-μm-wide buried-heterostruc⁃ture(BH)LWIR QCL ofλ~8.5μm with Y_(2)O_(3)metallic high-reflection(HR)and AR of~0.2%reflectivity coating demonstrates a maximum pulsed peak power of 2.19 W at 298 K,which is 149%higher than that of the uncoated device.For continuous-wave(CW)operation,by optimizing the reflectivity of the Y_(2)O_(3)AR coating,the maximum output power reaches 0.73 W,which is 91%higher than that of the uncoated device. 展开更多
关键词 quantum cascade lasers long-wave infrared optical facet coatings catastrophic optical mirror damage
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The second fusion of laser and aerospace-an inspiration for high energy lasers 被引量:1
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作者 Xiaojun Xu Rui Wang Zining Yang 《Opto-Electronic Advances》 SCIE EI CAS CSCD 2023年第6期52-60,共9页
Since the first laser was invented,the pursuit of high-energy lasers(HELs)has always been enthusiastic.The first revolution of HELs was pushed by the fusion of laser and aerospace in the 1960s,with the chemical rocket... Since the first laser was invented,the pursuit of high-energy lasers(HELs)has always been enthusiastic.The first revolution of HELs was pushed by the fusion of laser and aerospace in the 1960s,with the chemical rocket engines giving fresh impetus to the birth of gas flow and chemical lasers,which finally turned megawatt lasers from dream into reality.Nowadays,the development of HELs has entered the age of electricity as well as the rocket engines.The properties of current electric rocket engines are highly consistent with HELs’goals,including electrical driving,effective heat dissipation,little medium consumption and extremely light weight and size,which inspired a second fusion of laser and aerospace and motivated the exploration for potential HELs.As an exploratory attempt,a new configuration of diode pumped metastable rare gas laser was demonstrated,with the gain generator resembling an electric rocket-engine for improved power scaling ability. 展开更多
关键词 high energy laser HEL gas dynamic laser alkali laser electric thruster metastable rare gas
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Applications of lasers:A promising route toward low-cost fabrication of high-efficiency full-color micro-LED displays 被引量:2
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作者 Shouqiang Lai Shibiao Liu +5 位作者 Zilu Li Zhening Zhang Zhong Chen Rong Zhang Hao-Chung Kuo Tingzhu Wu 《Opto-Electronic Science》 2023年第10期12-32,共21页
Micro-light-emitting diodes(micro-LEDs)with outstanding performance are promising candidates for next-generation displays.To achieve the application of high-resolution displays such as meta-displays,virtual reality,an... Micro-light-emitting diodes(micro-LEDs)with outstanding performance are promising candidates for next-generation displays.To achieve the application of high-resolution displays such as meta-displays,virtual reality,and wearable electronics,the size of LEDs must be reduced to the micro-scale.Thus,traditional technology cannot meet the demand during the processing of micro-LEDs.Recently,lasers with short-duration pulses have attracted attention because of their unique advantages during micro-LED processing such as noncontact processing,adjustable energy and speed of the laser beam,no cutting force acting on the devices,high efficiency,and low cost.Herein,we review the techniques and principles of laser-based technologies for micro-LED displays,including chip dicing,geometry shaping,annealing,laserassisted bonding,laser lift-off,defect detection,laser repair,mass transfer,and optimization of quantum dot color conversion films.Moreover,the future prospects and challenges of laser-based techniques for micro-LED displays are discussed. 展开更多
关键词 laser micro-LED nano-processing defective detection laser repair mass transfer quantum dot
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Terahertz Generation Using Implanted InGaAs Photomixers and Multi-wavelength Quantum Dot Lasers 被引量:1
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作者 Y.Hou J.R.Liu +6 位作者 M.Buchanan A.J.Spring Thorpe P.J.Poole H.C.Liu Ke Wu Sjoerd Roorda X.P.Zhang 《Nano-Micro Letters》 SCIE EI CAS 2012年第1期10-13,共4页
We report on a study of terahertz(THz) generation using implanted In Ga As photomixers and multi-wavelength quantum dot lasers. We carry out In Ga As materials growth, optical characterization, device design and fabri... We report on a study of terahertz(THz) generation using implanted In Ga As photomixers and multi-wavelength quantum dot lasers. We carry out In Ga As materials growth, optical characterization, device design and fabrication, and photomixing experiments. This approach is capable of generating a comb of electromagnetic radiation from microwave to terahertz. For shortening photomixer carrier lifetime, we employ proton implantation into an epitaxial layer of lattice matched In Ga As grown on InP. Under a 1.55 μm multimode In GaAs/In GaAsP quantum dot laser excitation, a frequency comb with a constant frequency spacing of 50 GHz generated on the photomixer is measured, which corresponds to the beats of the laser longitudinal modes. The measurement is performed with a Fourier transform infrared spectrometer. This approach affords a convenient method to achieve a broadband multi-peak coherent THz source. 展开更多
关键词 Proton implanted In Ga As Trahertz Photomixer multi-wavelength quantum dot laser Fourier transform infrared spectroscopy
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Green Vertical‑Cavity Surface‑Emitting Lasers Based on InGaN Quantum Dots and Short Cavity 被引量:1
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作者 Tao Yang Yan‑Hui Chen +7 位作者 Ya‑Chao Wang Wei Ou Lei‑Ying Ying Yang Mei Ai‑Qin Tian Jian‑Ping Liu Hao‑Chung Guo Bao‑Ping Zhang 《Nano-Micro Letters》 SCIE EI CAS CSCD 2023年第12期115-125,共11页
Room temperature low threshold lasing of green GaNbased vertical cavity surface emitting laser(VCSEL)was demonstrated under continuous wave(CW)operation.By using self-formed InGaN quantum dots(QDs)as the active region... Room temperature low threshold lasing of green GaNbased vertical cavity surface emitting laser(VCSEL)was demonstrated under continuous wave(CW)operation.By using self-formed InGaN quantum dots(QDs)as the active region,the VCSEL emitting at 524.0 nm has a threshold current density of 51.97 A cm^(-2),the lowest ever reported.The QD epitaxial wafer featured with a high IQE of 69.94%and theδ-function-like density of states plays an important role in achieving low threshold current.Besides,a short cavity of the device(~4.0λ)is vital to enhance the spontaneous emission coupling factor to 0.094,increase the gain coefficient factor,and decrease the optical loss.To improve heat dissipation,AlN layer was used as the current confinement layer and electroplated copper plate was used to replace metal bonding.The results provide important guidance to achieving high performance GaN-based VCSELs. 展开更多
关键词 Green vertical cavity surface emitting laser GaN Low threshold InGaN quantum dots
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Backward scattering of laser plasma interactions from hundreds-of-joules broadband laser on thick target 被引量:1
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作者 Peipei Wang Honghai An +14 位作者 Zhiheng Fang Jun Xiong Zhiyong Xie Chen Wang Zhiyu He Guo Jia Ruirong Wang Shu Zheng Lan Xia Wei Feng Haitao Shi Wei Wang Jinren Sun Yanqi Gao Sizu Fu 《Matter and Radiation at Extremes》 SCIE EI CSCD 2024年第1期5-14,共10页
The use of broadband laser technology is a novel approach for inhibiting processes related to laser plasma interactions(LPIs).In this study,several preliminary experiments into broadband-laser-driven LPIs are carried ... The use of broadband laser technology is a novel approach for inhibiting processes related to laser plasma interactions(LPIs).In this study,several preliminary experiments into broadband-laser-driven LPIs are carried out using a newly established hundreds-of-joules broadband second-harmonic-generation laser facility.Through direct comparison with LPI results for a traditional narrowband laser,the actual LPI-suppression effect of the broadband laser is shown.The broadband laser had a clear suppressive effect on both back-stimulated Raman scattering and back-stimulated Brillouin scattering at laser intensities below 1×10^(15) W cm^(−2).An abnormal hot-electron phenomenon is also investigated,using targets of different thicknesses. 展开更多
关键词 SCATTERING laser hundreds
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Efficient multi-wavelength lasers made of Nd:GdLuAG crystal 被引量:1
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作者 赵永光 王正平 +3 位作者 于浩海 徐晓东 徐军 许心光 《Chinese Optics Letters》 SCIE EI CAS CSCD 2015年第2期57-61,共5页
Owing to the small differences between the cross-sections of the four emission peaks around 1.3 μm, an efficient four-wavelength synchronous launched laser is demonstrated using a Nd:Gd Lu AG crystal. The laser has ... Owing to the small differences between the cross-sections of the four emission peaks around 1.3 μm, an efficient four-wavelength synchronous launched laser is demonstrated using a Nd:Gd Lu AG crystal. The laser has no special resonator design. The maximum output power is 4.28 W, which corresponds to a conversion efficiency of 45.6%. For the Q-switching, the laser operated in dual-wavelength mode, and the single pulse energy is maintained at ~80 μJ. By calculating the population inversion density, multi-wavelength emission characteristics in both continuous wave and Q-switching lasers are discussed. 展开更多
关键词 Continuous wave lasers Optical data storage Q switched lasers
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Underwater four-quadrant dual-beam circumferential scanning laser fuze using nonlinear adaptive backscatter filter based on pauseable SAF-LMS algorithm 被引量:1
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作者 Guangbo Xu Bingting Zha +2 位作者 Hailu Yuan Zhen Zheng He Zhang 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第7期1-13,共13页
The phenomenon of a target echo peak overlapping with the backscattered echo peak significantly undermines the detection range and precision of underwater laser fuzes.To overcome this issue,we propose a four-quadrant ... The phenomenon of a target echo peak overlapping with the backscattered echo peak significantly undermines the detection range and precision of underwater laser fuzes.To overcome this issue,we propose a four-quadrant dual-beam circumferential scanning laser fuze to distinguish various interference signals and provide more real-time data for the backscatter filtering algorithm.This enhances the algorithm loading capability of the fuze.In order to address the problem of insufficient filtering capacity in existing linear backscatter filtering algorithms,we develop a nonlinear backscattering adaptive filter based on the spline adaptive filter least mean square(SAF-LMS)algorithm.We also designed an algorithm pause module to retain the original trend of the target echo peak,improving the time discrimination accuracy and anti-interference capability of the fuze.Finally,experiments are conducted with varying signal-to-noise ratios of the original underwater target echo signals.The experimental results show that the average signal-to-noise ratio before and after filtering can be improved by more than31 d B,with an increase of up to 76%in extreme detection distance. 展开更多
关键词 laser fuze Underwater laser detection Backscatter adaptive filter Spline least mean square algorithm Nonlinear filtering algorithm
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Laser spectroscopy imaging technique coupled withnanomaterials for cancer diagnosis: A review 被引量:1
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作者 Zhengying Peng Pengkun Yin +5 位作者 Dan Li Youyuan Chen Kaiqiang Shu Qingwen Fan Yixiang Duan Qingyu Lin 《Journal of Innovative Optical Health Sciences》 SCIE EI CSCD 2024年第1期1-27,共27页
Laser spectroscopic imaging techniques have received tremendous attention in the-eld of cancer diagnosis due to their high sensitivity,high temporal resolution,and short acquisition time.However,the limited tissue pen... Laser spectroscopic imaging techniques have received tremendous attention in the-eld of cancer diagnosis due to their high sensitivity,high temporal resolution,and short acquisition time.However,the limited tissue penetration of the laser is still a challenge for the in vivo diagnosis of deep-seated lesions.Nanomaterials have been universally integrated with spectroscopic imaging techniques for deeper cancer diagnosis in vivo.The components,morphology,and sizes of nanomaterials are delicately designed,which could realize cancer diagnosis in vivo or in situ.Considering the enhanced signal emitting from the nanomaterials,we emphasized their combination with spectroscopic imaging techniques for cancer diagnosis,like the surface-enhanced Raman scattering(SERS),photoacoustic,fluorescence,and laser-induced breakdown spectroscopy(LIBS).Applications ofthe above spectroscopic techniques offer new prospectsfor cancer diagnosis. 展开更多
关键词 laser spectroscopy tumor imaging tumor diagnosis NANOMATERIALS
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Influence of layer thickness on formation quality,microstructure,mechanical properties,and corrosion resistance of WE43 magnesium alloy fabricated by laser powder bed fusion 被引量:2
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作者 Bangzhao Yin Jinge Liu +7 位作者 Bo Peng Mengran Zhou Bingchuan Liu Xiaolin Ma Caimei Wang Peng Wen Yun Tian Yufeng Zheng 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2024年第4期1367-1385,共19页
Laser powder bed fusion(L-PBF)of Mg alloys has provided tremendous opportunities for customized production of aeronautical and medical parts.Layer thickness(LT)is of great significance to the L-PBF process but has not... Laser powder bed fusion(L-PBF)of Mg alloys has provided tremendous opportunities for customized production of aeronautical and medical parts.Layer thickness(LT)is of great significance to the L-PBF process but has not been studied for Mg alloys.In this study,WE43 Mg alloy bulk cubes,porous scaffolds,and thin walls with layer thicknesses of 10,20,30,and 40μm were fabricated.The required laser energy input increased with increasing layer thickness and was different for the bulk cubes and porous scaffolds.Porosity tended to occur at the connection joints in porous scaffolds for LT40 and could be eliminated by reducing the laser energy input.For thin wall parts,a large overhang angle or a small wall thickness resulted in porosity when a large layer thicknesses was used,and the porosity disappeared by reducing the layer thickness or laser energy input.A deeper keyhole penetration was found in all occasions with porosity,explaining the influence of layer thickness,geometrical structure,and laser energy input on the porosity.All the samples achieved a high fusion quality with a relative density of over 99.5%using the optimized laser energy input.The increased layer thickness resulted to more precipitation phases,finer grain sizes and decreased grain texture.With the similar high fusion quality,the tensile strength and elongation of bulk samples were significantly improved from 257 MPa and 1.41%with the 10μm layer to 287 MPa and 15.12%with the 40μm layer,in accordance with the microstructural change.The effect of layer thickness on the compressive properties of porous scaffolds was limited.However,the corrosion rate of bulk samples accelerated with increasing the layer thickness,mainly attributed to the increased number of precipitation phases. 展开更多
关键词 Magnesium alloy WE43 laser powder bed fusion Layer thickness Process optimization
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Diagnosis of poorly differentiated adenocarcinoma of the stomach by confocal laser endomicroscopy:A case report 被引量:3
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作者 Jia-Xin Lou Yong Wu +3 位作者 Muren Huhe Jing-Jie Zhang Dong-Wu Jia Zhen-Yu Jiang 《World Journal of Clinical Cases》 SCIE 2024年第8期1481-1486,共6页
BACKGROUND In recent years,confocal laser endomicroscopy(CLE)has become a new endoscopic imaging technology at the microscopic level,which is extensively performed for real-time in vivo histological examination.CLE ca... BACKGROUND In recent years,confocal laser endomicroscopy(CLE)has become a new endoscopic imaging technology at the microscopic level,which is extensively performed for real-time in vivo histological examination.CLE can be performed to distinguish benign from malignant lesions.In this study,we diagnosed using CLE an asymptomatic patient with poorly differentiated gastric adenocarcinoma.CASE SUMMARY A 63-year-old woman was diagnosed with gastric mucosal lesions,which may be gastric cancer,in the small curvature of the stomach by gastroscopy.She consented to undergo CLE for morphological observation of the gastric mucosa.Through the combination of CLE diagnosis and postoperative pathology,the intraoperative CLE diagnosis was considered to be reliable.According to our experience,CLE can be performed as the first choice for the diagnosis of gastric cancer.CONCLUSION CLE has several advantages over pathological diagnosis.We believe that CLE has great potential in the diagnosis of benign and malignant gastric lesions. 展开更多
关键词 Confocal laser endomicroscopy Poorly differentiated gastric adenocarcinoma DIAGNOSIS Early stage Case report
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