Three-dimensional magnetic reconnection in complex multiple X-point configurations in an ancient solar-lunar terrestrial system

Magnetic reconnection processes in three-dimensional(3D)complex field configurations have been investigated in different magneto-plasma systems in space,laboratory,and astrophysical systems.Two-dimensional(2D)features of magnetic reconnection have been well developed and applied successfully to systems with symmetrical property,such as toroidal fusion plasmas and laboratory experiments with an axial symmetry.But in asymmetric systems,the 3D features are inevitably different from those in the 2D case.Magnetic reconnection structures in multiple celestial body systems,particularly star-planet-Moon systems,bring fresh insights to the understanding of the 3D geometry of reconnection.Thus,we take magnetic reconnection in an ancient solar-lunar terrestrial magneto-plasma system as an example by using its crucial parameters approximately estimated already and also some specific applications in pathways for energy and matter transports among Earth,ancient Moon,and the interplanetary magnetic field(IMF).Then,magnetic reconnection of the ancient lunar-terrestrial magnetospheres with the IMF is investigated numerically in this work.In a 3D simulation for the Earth-Moon-IMF system,topological features of complex magnetic reconnection configurations and dynamical characteristics of magnetic reconnection processes are studied.It is found that a coupled lunar-terrestrial magnetosphere is formed,and under various IMF orientations,multiple X-points emerge at distinct locations,showing three typical magnetic reconnection structures in such a geometry,i.e.,the X-line,the triple current sheets,and the A-B null pairs.The results can conduce to further understanding of reconnection physics in 3D for plasmas in complex magnetic configurations,and also a possible mechanism for energy and matters transport in evolutions of similar astrophysical systems.

Infiltration by monocytes of the central nervous system and its role in multiple sclerosis: reflections on therapeutic strategies

Mononuclear macrophage infiltration in the central nervous system is a prominent feature of neuroinflammation. Recent studies on the pathogenesis and progression of multiple sclerosis have highlighted the multiple roles of mononuclear macrophages in the neuroinflammatory process. Monocytes play a significant role in neuroinflammation, and managing neuroinflammation by manipulating peripheral monocytes stands out as an effective strategy for the treatment of multiple sclerosis, leading to improved patient outcomes. This review outlines the steps involved in the entry of myeloid monocytes into the central nervous system that are targets for effective intervention: the activation of bone marrow hematopoiesis, migration of monocytes in the blood, and penetration of the blood–brain barrier by monocytes. Finally, we summarize the different monocyte subpopulations and their effects on the central nervous system based on phenotypic differences. As activated microglia resemble monocyte-derived macrophages, it is important to accurately identify the role of monocyte-derived macrophages in disease. Depending on the roles played by monocyte-derived macrophages at different stages of the disease, several of these processes can be interrupted to limit neuroinflammation and improve patient prognosis. Here, we discuss possible strategies to target monocytes in neurological diseases, focusing on three key aspects of monocyte infiltration into the central nervous system, to provide new ideas for the treatment of neurodegenerative diseases.

Three-dimensional positions of scattering centers reconstruction from multiple SAR images based on radargrammetry

A method and procedure is presented to reconstruct three-dimensional(3D) positions of scattering centers from multiple synthetic aperture radar(SAR) images. Firstly, two-dimensional(2D) attribute scattering centers of targets are extracted from 2D SAR images. Secondly, similarity measure is developed based on 2D attributed scatter centers' location, type, and radargrammetry principle between multiple SAR images. By this similarity, we can associate 2D scatter centers and then obtain candidate 3D scattering centers. Thirdly, these candidate scattering centers are clustered in 3D space to reconstruct final 3D positions. Compared with presented methods, the proposed method has a capability of describing distributed scattering center, reduces false and missing 3D scattering centers, and has fewer restrictionson modeling data. Finally, results of experiments have demonstrated the effectiveness of the proposed method.

Optical encryption of multiple three-dimensional objects based on multiple interferences and single-pixel digital holography

We present an optical encryption method of multiple three-dimensional objects based on multiple interferences and single-pixel digital holography. By modifying the Mach-Zehnder interferometer, the interference of the multiple objects beams and the one reference beam is used to simultaneously encrypt multiple objects into a ciphertext. During decryption, each three-dimensional object can be decrypted independently without having to decrypt other objects. Since the single- pixel digital holography based on compressive sensing theory is introduced, the encrypted data of this method is effectively reduced. In addition, recording fewer encrypted data can greatly reduce the bandwidth of network transmission. Moreover, the compressive sensing essentially serves as a secret key that makes an intruder attack invalid, which means that the system is more secure than the conventional encryption method. Simulation results demonstrate the feasibility of the proposed method and show that the system has good security performance.

Analysis of multiple scattering from two-dimensional dielectric sea surface with iterative Kirchhoff approximation

An iterative method in the Kirchhoff approximation is proposed for high frequency multiple electromagnetic scattering from two-dimensional dielectric sea surface. The multiple interaction of the scattering field is characterized with the corrected electromagnetic currents of the wind-driven sea surface. The actual surface currents are approximated with the iterative solution of the corrected currents. A newly developed sea spectrum, Elfouhaily spectrum, is utilized to build the sea surface model. The shadowing correction is improved by the Dept-Buffer algorithm. The validity of the iterative Kirchhoff approximation is verified by the agreement of backscattering coefficients with the measured data.

Modified Laguerre spectral and pseudospectral methods for nonlinear partial differential equations in multiple dimensions

The Laguerre spectral and pseudospectral methods are investigated for multidimensional nonlinear partial differential equations. Some results on the modified Laguerre orthogonal approximation and interpolation are established, which play important roles in the related numerical methods for unbounded domains. As an example, the modified Laguerre spectral and pseudospectral methods are proposed for two-dimensional Logistic equation. The stability and convergence of the suggested schemes are proved. Numerical results demonstrate the high accuracy of these approaches.

A new multiple-factor clustering method considering both box fractal dimension and orientation of joints

The paper proposes a new multiple-factor clustering method(NMFCM)with consideration of both box fractal dimension(BFD)and orientation of joints.This method assumes that the BFDs of different clusters were uneven,and clustering was performed by redistributing the joints near the boundaries of clusters on a polar map to maximize an index for estimating the difference of the BFD(DBFD).Three main aspects were studied to develop the NMFCM.First,procedures of the NMFCM and reasonableness of assumptions were illustrated.Second,main factors affecting the NMFCM were investigated by numerical simulations with disk joint models.Finally,two different sections of a rock slope were studied to verify the practicability of the NMFCM.The results demonstrated that:(1)The NMFCM was practical and could effectively alleviate the problem of hard boundary during clustering;(2)The DBFD tended to increase after the improvement of clustering accuracy;(3)The improvement degree of the NMFCM clustering accuracy was mainly influenced by three parameters,namely,the number of clusters,number of redistributed joints,and total number of joints;and(4)The accuracy rate of clustering could be effectively improved by the NMFCM.

Outcome assessment of stroke convalescence using multiple scales based on different dimensions

BACKGROUND: Convalescence is an important stage of stroke treatment. A lot of patients have somatic and mental disorders at various degrees. The primary standard can only reflect partial conditions of somatic disorder; in addition, multiple dimensions of patients at the phase of stroke convalescence are further observed by using a lot of standards, such as signs and symptoms of traditional Chinese medicine, daily activity and psychological status. OBJECTIVE: To analyze the outcome assessments of the cases of stroke convalescence measured with different criteria consisting of various dimensions by a cross-sectional investigation of the condition of stroke convalescent patients. DESIGN: Scale evaluation. SETTING: Departments of Clinical Epidemiology Exploratory Development and Neurology, the Second Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine; National Center for Training of Design, Measurement and Evaluation in Clinical Research,Guangzhou University of Traditional Chinese Medicine. PARTICIPANTS: A total of 194 stroke convalescent patients treated in the Second Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine from July 26, 2000 to February 28, 2001 were taken as subjects of the study. There were 126 males and 68 females aged from 40 to 89 years, and the illness course ranged from 14 to 181 days. All patients met diagnosis-treatment criteria of stroke (the second version)[DTCS(V2.0)] and various kinds of diagnostic points of cerebrovascular diseases; moreover, all patients provided confirmed consents. METHODS: They were assessed by assessment methods including the following assessment instruments: DTCS(V2.0), self-designed scale of traditional Chinese medicine (TCM) symptoms (28 symptoms and physical signs were scored as 0, 1, 2 marks from none to severity), modified Edinburgh-Scandinavia stroke scale (a total of 45 marks, 0 to 15 marks as mild defect, 16 to 30 as moderate defect, 31 to 45 as severe defect), modified Barthel activities of daily life (ADL) index (a total of 100 marks, less than 60 marks as unable self-care), vitality and mental health (subscales derived from Health Survey Questionnaire, SF-36). The collected data from scales and inter-scale correlation were processed by the statistic methods mainly including descriptive analysis, Spearmen correlation analysis, factor analysis, etc. MAIN OUTCOME MEASURES: ① Average scores of scales and criteria; ② correlation between modified Edinburgh-Scandinavia stroke scale and other scales. RESULTS: All of the patients completed the assessment, and analyzed in the final analysis. ① The average scores of the scales and criteria: The average scores of DTCS(V2.0), self-designed scale of TCM symptoms, modified Edinburgh-Scandinavia stroke scale, modified Barthel ADL index, vitality and mental health scales were 6.51±6.29, 13.73±6.97, 7.56±7.35, 63.58±23.68, 52.79±23.32 and 62.83±22.75 respectively. ② Correlation between modified Edinburgh-Scandinavia stroke scale and other scales: The Spearman correlation coefficients (R ’) of modified Edinburgh-Scandinavia stroke scale with diagnosis-treatment criteria of stroke, scales of TCM symptoms, modified Barthel ADL index, vitality scale and mental health scale were 20.885, 0.302, -0.824, -0.294 and -0.258 respectively. CONCLUSION: The modified Edinburgh-Scandinavia stroke scale and DTCS(V2.0) shared the same assessment dimension, so they can be mutually alternated in some clinical practices. Discrepancy in measurements of health status was gained due to the diverse dimensions applied in outcome assessments. It is necessary to build up a multi-dimensional assessment criteria system, such as signs and symptoms, daily activities and psychological status, for assessing the stroke convalescent cases in a more comprehensive scope and reflecting the efficacy of TCM treatment scientifically.

A generalized cover renewal strategy for multiple crack propagation in two-dimensional numerical manifold method

Partition of unity based numerical manifold method can solve continuous and discontinuous problems in a unified framework with a two-cover system,i.e.,the mathematical cover and physical cover.However,renewal of the topology of the two-cover system poses a challenge for multiple crack propagation problems and there are few references.In this study,a robust and efficient strategy is proposed to update the cover system of the numerical manifold method in simulation of multiple crack propagation problems.The proposed algorithm updates the cover system with a bottom-up process:1)identification of fractured manifold elements according to the previous and latest crack tip position;and 2)local topological update of the manifold elements,physical patches,block boundary loops,and non-persistent joint loops according to the scenario classification of the propagating crack.The proposed crack tracking strategy and classification of the renewal cases promote a robust and efficient cover renewal algorithm for multiple crack propagation analysis.Three crack propagation examples show that the proposed algorithm performs well in updating the cover system.This cover renewal methodology can be extended for numerical manifold method with polygonal mathematical covers.

Multiple Dimensions Convey Design and Application in CIS based on CG Technique

In the art design field, CG technique has been applied in many aspects like third dimension graphical display, human-computer interaction, virtual reality, three-dimensional cartoon and so on. In the meanwhile, the applications reflected in art design was appeared in computer assisted convey design, bothway or multi-ways interactive convey design and multimedia convey design. Computer assisted convey design included the application of the most CG technique in visual. Interactive convey design reflected interaction, which was the most obvious character of CG. However, multimedia convey design was used not only in CG technique, but also in digital media techniaue.

A fast and precise three-dimensional measurement system based on multiple parallel line lasers

This paper conducts a trade-off between efficiency and accuracy of three-dimensional(3 D)shape measurement based on the triangulation principle,and introduces a flying and precise 3 D shape measurement method based on multiple parallel line lasers.Firstly,we establish the measurement model of the multiple parallel line lasers system,and introduce the concept that multiple base planes can help to deduce the unified formula of the measurement system and are used in simplifying the process of the calibration.Then,the constraint of the line spatial frequency,which maximizes the measurement efficiency while ensuring accuracy,is determined according to the height distribution of the object.Secondly,the simulation analyzing the variation of the systemic resolution quantitatively under the circumstance of a set of specific parameters is performed,which provides a fundamental thesis for option of the four system parameters.Thirdly,for the application of the precision measurement in the industrial field,additional profiles are acquired to improve the lateral resolution by applying a motor to scan the 3 D surface.Finally,compared with the line laser,the experimental study shows that the present method of obtaining 41220 points per frame improves the measurement efficiency.Furthermore,the accuracy and the process of the calibration are advanced in comparison with the existing multiple-line laser and the structured light makes an accuracy better than 0.22 mm at a distance of 956.02 mm.

THE THREE-DIMENSIONAL FUNDAMENTAL SOLUTION TO STOKES FLOW IN THE OBLATE SPHEROIDAL COORDINATES WITH APPLICATIONS TO MULTIPLES SPHEROID PROBLEMS

A new three-dimensional fundamental solution to the Stokes flow was proposed by transforming the solid harmonic functions in Lamb's solution into expressions in terms Of the oblate spheroidal coordinates. These fundamental solutions are advantageous in treating flows past an arbitrary number of arbitrarily positioned and oriented oblate spheroids. The least squares technique was adopted herein so that the convergence difficulties often encountered in solving three-dimensional problems were completely avoided. The examples demonstrate that present approach is highly accurate, consistently stable and computationally efficient. The oblate spheroid may be used to model a variety of particle shapes between a circular disk and a sphere. For the first time, the effect of various geometric factors on the forces and torques exerted on two oblate spheroids were systematically studied by using the proposed fundamental solutions. The generality of this approach was illustrated by two problems of three spheroids.

Gut flora in multiple sclerosis:implications for pathogenesis and treatment

Multiple sclerosis is an inflammatory disorder chara cterized by inflammation,demyelination,and neurodegeneration in the central nervous system.Although current first-line therapies can help manage symptoms and slow down disease progression,there is no cure for multiple sclerosis.The gut-brain axis refers to complex communications between the gut flo ra and the immune,nervous,and endocrine systems,which bridges the functions of the gut and the brain.Disruptions in the gut flora,termed dys biosis,can lead to systemic inflammation,leaky gut syndrome,and increased susceptibility to infections.The pathogenesis of multiple sclerosis involves a combination of genetic and environmental factors,and gut flora may play a pivotal role in regulating immune responses related to multiple scle rosis.To develop more effective therapies for multiple scle rosis,we should further uncover the disease processes involved in multiple sclerosis and gain a better understanding of the gut-brain axis.This review provides an overview of the role of the gut flora in multiple scle rosis.

Improved Multiple-Scenario Radio Network Dimensioning for WCDMA

In wideband code division multiple access (WCDMA) cellular systems, the coverage radius of a cell depends on its current capacity level. As a result, existing WCDMA radio network dimensioning approaches require that coverage and capacity planning be carried out jointly in an iterative manner in order to obtain the minimum site count needed while fulfilling both coverage and capacity requirements. This requires relatively long computational time, particularly when there are many scenarios or what-if cases to be considered. To overcome this problem, we propose an alternative radio network dimensioning approach where coverage planning and capacity planning can be carried out separately to reduce computational time. Besides, a portion of the values calculated in the initial iteration is preserved in a lookup graph, allowing future what-if analysis to be accomplished rapidly. Simulation results show that, unlike the existing approach, the planning and what-if analysis times of the proposed dimensioning approach are independent of the number of sce-narios considered. Lastly, we present a few case studies and show that the proposed dimensioning method can give the same prediction accuracy as the existing method.

A Review on Vibration Control of Multiple Cylinders Subjected to FlowInduced Vibrations

The fatigue damage caused by flow-induced vibration(FIV)is one of the major concerns for multiple cylindrical structures in many engineering applications.The FIV suppression is of great importance for the security of many cylindrical structures.Many active and passive control methods have been employed for the vibration suppression of an isolated cylinder undergoing vortex-induced vibrations(VIV).The FIV suppression methods are mainly extended to the multiple cylinders from the vibration control of the isolated cylinder.Due to the mutual interference between the multiple cylinders,the FIV mechanism is more complex than the VIV mechanism,which makes a great challenge for the FIV suppression.Some efforts have been devoted to vibration suppression of multiple cylinder systems undergoing FIV over the past two decades.The control methods,such as helical strakes,splitter plates,control rods and flexible sheets,are not always effective,depending on many influence factors,such as the spacing ratio,the arrangement geometrical shape,the flow velocity and the parameters of the vibration control devices.The FIV response,hydrodynamic features and wake patterns of the multiple cylinders equipped with vibration control devices are reviewed and summarized.The FIV suppression efficiency of the vibration control methods are analyzed and compared considering different influence factors.Further research on the FIV suppression of multiple cylinders is suggested to provide insight for the development of FIV control methods and promote engineering applications of FIV control methods.

Single Zone, Zero Dimensional Model of Diesel Multiple-Injection

A detailed single zone, zero dimensional model of diesel multiple-injection system was developed from first principle, for compression, combustion and expansion processes for direct injection diesel engine. Equilibrium equation of Extended Zeldolvich Mechanism (EZM) for NOx formation was incorporated to predict NOx emission. A different approach was assumed for the equilibrium temperature. An approach of using the average cycle temperature within NOx formation region was used in the EZM equilibrium equation. The model codes were implemented in MATLAB. This model is developed to investigate the effects of both single and multiple-pulse fuel injection strategies on engine performance and NOx emissions. The results obtained from the model were validated with experimental data available in the literature. Results obtained showed that the use of average cycle temperature within the NOx formation temperature region could be useful in predicting NOx formation with reasonable degree of accuracy. Injection timing, mass ratio of injected fuel, and dwell between pulses have significant effects on the NOx emission and engine performance. The results also show that as the number of pulses increases, NOx emission and engine performance decrease. For optimal balance between NOx and engine performance, mass of the pilot injection should be between 10 and 25% of the total mass of fuel used per cycle.

Linear paired electrolysis of furfural to furoic acid at both anode and cathode in a multiple redox mediated system

Implementing a new energy-saving electrochemical synthesis system with high commercial value is a strategy of the sustainable development for upgrading the bulk chemicals preparation technology in the future.Here,we report a multiple redox-mediated linear paired electrolysis system,combining the hydrogen peroxide mediated cathode process with the I2 mediated anode process,and realize the conversion of furfural to furoic acid in both side of the dividedflow cell simultaneously.By reasonably controlling the cathode potential,the undesired water splitting reaction and furfural reduction side reactions are avoided.Under the galvanostatic electrolysis,the two-mediated electrode processes have good compatibility,which reduce the energy consumption by about 22%while improving the electronic efficiency by about 125%.This system provides a green electrochemical synthesis route with commercial prospects.

Using Multiple Correspondence Analysis to Measure Multidimensional Poverty in Congo

The following analysis is based on a multidimensional understanding of poverty using a nonmonetary basic needs approach. It is ground on data from the first survey on household living conditions for poverty assessment, conducted by the National Institute of Statistics of Congo in 2005. Multiple Correspondence Analysis is applied to construct a composite indicator by aggregating several attributes likely to reflect the poverty of individuals or households. The application shows that Congolese households are not affected by the same type of poverty. Three types of non-monetary poverty are identified: infrastructure poverty, vulnerability of human existence and poverty of comfort. These households were then classified according to the composite indicator of Poverty. The results show that the incidence of poverty corresponds to the weight of poor class of about 70.67%.

Early detection of multiple endocrine neoplasia type 1: A case report

BACKGROUND Multiple endocrine neoplasias(MENs)are a group of hereditary diseases invol-ving multiple endocrine glands,and their prevalence is low.MEN type 1(MEN1)has diverse clinical manifestations,mainly involving the parathyroid glands,gastrointestinal tract,pancreas and pituitary gland,making it easy to miss the clinical diagnosis.CASE SUMMARY We present the case of a patient in whom MEN1 was detected early.A middle-aged male with recurrent abdominal pain and diarrhea was admitted to the hos-pital.Blood tests at admission revealed hypercalcemia and hypophosphatemia,and emission computed tomography of the parathyroid glands revealed a hy-perfunctioning parathyroid lesion.Gastroscopy findings suggested a duodenal bulge and ulceration.Ultrasound endoscopy revealed a hypoechoic lesion in the duodenal bulb.Further blood tests revealed elevated levels of serum gastrin.Surgery was performed,and pathological analysis of the surgical specimens revealed a parathyroid adenoma after parathyroidectomy and a neuroendocrine tumor after duodenal bulbectomy.The time from onset to the definitive diagnosis of MEN1 was only approximately 1 year.CONCLUSION For patients who present with gastrointestinal symptoms accompanied by hyper-calcemia and hypophosphatemia,clinicians need to be alert to the possibility of MEN1.

Multiple Response Optimization of Dimensional Accuracy of Nimonic Alloy Miniature Gear Machined on Wire Edm Using Entropy Topsis Andpareto Anova

The purpose of this research is to obtain the optimum cutting parameters to achieve the dimensional accuracy of Nimonic alloy miniature gear manufactured using Wire EDM.The cutting parameters investigated in this study are current,pulse on time(PON),pulse off time(POFF),wire tension(WT)and dielectric fluids.Ethylene glycol,nanopowder of alumina and oxygen are mixed to demineralized water to prepare novel dielectric fluids.Deviation in inner diameter,deviation in outer diameter,deviation in land and deviation in tooth width are considered to check the dimensional accuracy.Taguchi L_(16) is employed for experimental design and multiple response optimization is performed using Entropy TOPSIS and Pareto ANOVA.Results indicate that pulse on time is the most notable parameter for good dimensional accuracy followed by dielectric fluid,current,pulse off time and wire tension.Ethylene glycol mixed demineralized water is preferred for low dimensional deviation.The optimum WEDM parameters are pulse on time at 20μs,Ethylene glycol mixed demineralized water dielectric fluid,current at 3 A,pulse off time at 4μs,and wire tension at 18 N.