This study investigates the factors that impact farmers'adoption of risk management strategies(RMS)in Pakistan during times of uncertainty.The study examines farmers'adoption of RMS using both multinomial prob...This study investigates the factors that impact farmers'adoption of risk management strategies(RMS)in Pakistan during times of uncertainty.The study examines farmers'adoption of RMS using both multinomial probit(MNP)and multivariate probit(MVP).Data were collected from 382 farmers sampled from four districts in KhyberPakhtunkhwa(KP)province of Pakistan via a multistage sampling technique.This study utilizes the MNP model,considering the assumption of Independence of Irrelevant Alternatives(IIA)and incorporating correlated error terms.The objective is to understand farmers'behavior in risky situations and determine if there is heterogeneity.Results are compared with the MVP model to assess robustness and gain deeper understanding of farmers'decisionmaking processes.The research findings reveal that our results are robust,and farmers behave homogeneously in various RMS scenarios.Farmers adopt RMS individually or in combination to mitigate the adverse effects of natural calamities on their livelihood.The risk-averse farmers,who perceive weather-related risks as a threat,access credits and information,and have farms close to a river are more likely to adopt RMS,irrespective of the format of the strategies available.Moreover,the predicted probabilities and correlation of the RMS and RM categories have strengthened our model estimation.These findings provide insights into the behavior of farmers in adopting RMS which are helpful for policymakers and stakeholders in developing strategies to mitigate the impacts of natural calamities on farmers.展开更多
Blast furnace (BF) ironmaking process has complex and nonlinear dynamic characteristics. The molten iron temperature (MIT) as well as Si, P and S contents of molten iron is difficult to be directly measured online...Blast furnace (BF) ironmaking process has complex and nonlinear dynamic characteristics. The molten iron temperature (MIT) as well as Si, P and S contents of molten iron is difficult to be directly measured online, and large-time delay exists in offline analysis through laboratory sampling. A nonlinear multivariate intelligent modeling method was proposed for molten iron quality (MIQ) based on principal component analysis (PCA) and dynamic ge- netic neural network. The modeling method used the practical data processed by PCA dimension reduction as inputs of the dynamic artificial neural network (ANN). A dynamic feedback link was introduced to produce a dynamic neu- ral network on the basis of traditional back propagation ANN. The proposed model improved the dynamic adaptabili- ty of networks and solved the strong fluctuation and resistance problem in a nonlinear dynamic system. Moreover, a new hybrid training method was presented where adaptive genetic algorithms (AGA) and ANN were integrated, which could improve network convergence speed and avoid network into local minima. The proposed method made it easier for operators to understand the inside status of blast furnace and offered real-time and reliable feedback infor- mation for realizing close-loop control for MIQ. Industrial experiments were made through the proposed model based on data collected from a practical steel company. The accuracy could meet the requirements of actual operation.展开更多
Most of the existing multivariable grey models are based on the 1-order derivative and 1-order accumulation, which makes the parameters unable to be adjusted according to the data characteristics of the actual problem...Most of the existing multivariable grey models are based on the 1-order derivative and 1-order accumulation, which makes the parameters unable to be adjusted according to the data characteristics of the actual problems. The results about fractional derivative multivariable grey models are very few at present. In this paper, a multivariable Caputo fractional derivative grey model with convolution integral CFGMC(q, N) is proposed. First, the Caputo fractional difference is used to discretize the model, and the least square method is used to solve the parameters. The orders of accumulations and differential equations are determined by using particle swarm optimization(PSO). Then, the analytical solution of the model is obtained by using the Laplace transform, and the convergence and divergence of series in analytical solutions are also discussed. Finally, the CFGMC(q, N) model is used to predict the municipal solid waste(MSW). Compared with other competition models, the model has the best prediction effect. This study enriches the model form of the multivariable grey model, expands the scope of application, and provides a new idea for the development of fractional derivative grey model.展开更多
Artemisinins tested against W-2 strains of malaria falciparum are investigated with molecular electrostatic potential (MEP), in an attempt to identify key features of the compounds that are necessary for their activit...Artemisinins tested against W-2 strains of malaria falciparum are investigated with molecular electrostatic potential (MEP), in an attempt to identify key features of the compounds that are necessary for their activities, as well as to investigate likely interactions with the receptor in a biological process and to use that information to propose new molecules. In order to discover the best geometry involving the ligand-receptor complexes (heme) studied and help in the proposition of the new derivatives, molecular simulations of interactions between the most negative charged region around the peroxide and heme locates (the ones around the Fe2+ ion) were carried out. In addition, PCA (principal components analysis), HCA (hierarchical cluster analysis), SDA (stepwise discriminant analysis), and KNN (K-nearest neighbor) multivariate models were employed to investigate which descriptors are responsible for the classification between the higher and lower antimalarial activity of the compounds, and also this information was used to propose new potentially active molecules. The information accumulated in studies of MEP, molecular docking, and multivariate analysis supported the proposal of new structures with potential antimalarial activities. The multivariate models constructed were applied to the new structures and indicated numbers 19 and 20 as the most prominent for syntheses and biological assays.展开更多
BACKGROUNDSpontaneous bacterial peritonitis (SBP) is a detrimental infection of the asciticfluid in liver cirrhosis patients, with high mortality and morbidity. Earlydiagnosis and timely antibiotic administration have...BACKGROUNDSpontaneous bacterial peritonitis (SBP) is a detrimental infection of the asciticfluid in liver cirrhosis patients, with high mortality and morbidity. Earlydiagnosis and timely antibiotic administration have successfully decreased themortality rate to 20%-25%. However, many patients cannot be diagnosed in theearly stages due to the absence of classical SBP symptoms. Early diagnosis ofasymptomatic SBP remains a great challenge in the clinic.AIMTo establish a multivariate predictive model for early diagnosis of asymptomaticSBP using positive microbial cultures from liver cirrhosis patients with ascites.METHODSA total of 98 asymptomatic SBP patients and 98 ascites liver cirrhosis patients withnegative microbial cultures were included in the case and control groups,respectively. Multiple linear stepwise regression analysis was performed toidentify potential indicators for asymptomatic SBP diagnosis. The diagnosticperformance of the model was estimated using the receiver operatingcharacteristic curve.RESULTSPatients in the case group were more likely to have advanced disease stages,cirrhosis related-complications, worsened hematology and ascites, and higher mortality. Based on multivariate analysis, the predictive model was as follows: y (P) = 0.018 + 0.312 × MELD (model of end-stage liver disease) + 0.263 × PMN(ascites polymorphonuclear) + 0.184 × N (blood neutrophil percentage) + 0.233 ×HCC (hepatocellular carcinoma) + 0.189 × renal dysfunction. The area under thecurve value of the established model was 0.872, revealing its high diagnosticpotential. The diagnostic sensitivity was 73.5% (72/98), the specificity was 86.7%(85/98), and the diagnostic efficacy was 80.1%.CONCLUSIONOur predictive model is based on the MELD score, polymorphonuclear cells,blood N, hepatocellular carcinoma, and renal dysfunction. This model mayimprove the early diagnosis of asymptomatic SBP.展开更多
Background: Leaf Area Index(LAI) is an important parameter used in monitoring and modeling of forest ecosystems. The aim of this study was to evaluate performance of the artificial neural network(ANN) models to predic...Background: Leaf Area Index(LAI) is an important parameter used in monitoring and modeling of forest ecosystems. The aim of this study was to evaluate performance of the artificial neural network(ANN) models to predict the LAI by comparing the regression analysis models as the classical method in these pure and even-aged Crimean pine forest stands.Methods: One hundred eight temporary sample plots were collected from Crimean pine forest stands to estimate stand parameters. Each sample plot was imaged with hemispherical photographs to detect the LAI. The partial correlation analysis was used to assess the relationships between the stand LAI values and stand parameters, and the multivariate linear regression analysis was used to predict the LAI from stand parameters. Different artificial neural network models comprising different number of neuron and transfer functions were trained and used to predict the LAI of forest stands.Results: The correlation coefficients between LAI and stand parameters(stand number of trees, basal area, the quadratic mean diameter, stand density and stand age) were significant at the level of 0.01. The stand age, number of trees, site index, and basal area were independent parameters in the most successful regression model predicted LAI values using stand parameters(R_(adj)~2=0.5431). As corresponding method to predict the interactions between the stand LAI values and stand parameters, the neural network architecture based on the RBF 4-19-1 with Gaussian activation function in hidden layer and the identity activation function in output layer performed better in predicting LAI(SSE(12.1040), MSE(0.1223), RMSE(0.3497), AIC(0.1040), BIC(-77.7310) and R^2(0.6392)) compared to the other studied techniques.Conclusion: The ANN outperformed the multivariate regression techniques in predicting LAI from stand parameters. The ANN models, developed in this study, may aid in making forest management planning in study forest stands.展开更多
The paper considers a multivariate partially linear model under independent errors,and investigates the asymptotic bias and variance-covariance for parametric component βand nonparametric component F(·)by the ...The paper considers a multivariate partially linear model under independent errors,and investigates the asymptotic bias and variance-covariance for parametric component βand nonparametric component F(·)by the GJS estimator and Kernel estimation.展开更多
The reservoir volumetric approach represents a widely accepted, but flawed method of petroleum play resource calculation. In this paper, we propose a combination of techniques that can improve the applicability and qu...The reservoir volumetric approach represents a widely accepted, but flawed method of petroleum play resource calculation. In this paper, we propose a combination of techniques that can improve the applicability and quality of the resource estimation. These techniques include: 1) the use of the Multivariate Discovery Process model (MDP) to derive unbiased distribution parameters of reservoir volumetric variables and to reveal correlations among the variables; 2) the use of the Geo-anchored method to estimate simultaneously the number of oil and gas pools in the same play; and 3) the crossvalidation of assessment results from different methods. These techniques are illustrated by using an example of crude oil and natural gas resource assessment of the Sverdrup Basin, Canadian Archipelago. The example shows that when direct volumetric measurements of the untested prospects are not available, the MDP model can help derive unbiased estimates of the distribution parameters by using information from the discovered oil and gas accumulations. It also shows that an estimation of the number of oil and gas accumulations and associated size ranges from a discovery process model can provide an alternative and efficient approach when inadequate geological data hinder the estimation. Cross-examination of assessment results derived using different methods allows one to focus on and analyze the causes for the major differences, thus providing a more reliable assessment outcome.展开更多
For multivariate linear model Y=XΘ+ε, ~N(0, σ 2ΣV), this paper is concerned with the admissibility of linear estimators of estimable function SXΘ in the class of all estimators. All admissible linear estimators ...For multivariate linear model Y=XΘ+ε, ~N(0, σ 2ΣV), this paper is concerned with the admissibility of linear estimators of estimable function SXΘ in the class of all estimators. All admissible linear estimators of SXΘ are given under each of four definitions of admissibility.展开更多
Considering the problems that should be solved in the synthetic earthquake prediction at present, a new model is proposed in the paper. It is called joint multivariate statistical model combined by principal component...Considering the problems that should be solved in the synthetic earthquake prediction at present, a new model is proposed in the paper. It is called joint multivariate statistical model combined by principal component analysis with discriminatory analysis. Principal component analysis and discriminatory analysis are very important theories in multivariate statistical analysis that has developed quickly in the late thirty years. By means of maximization information method, we choose several earthquake prediction factors whose cumulative proportions of total sam-ple variances are beyond 90% from numerous earthquake prediction factors. The paper applies regression analysis and Mahalanobis discrimination to extrapolating synthetic prediction. Furthermore, we use this model to charac-terize and predict earthquakes in North China (30~42N, 108~125E) and better prediction results are obtained.展开更多
In this paper, compression LS estimate (k) of the regression coefficient B isconsidered when the design matrix present ill-condition in multivariate linear model.The MSE (mean square error)of the estimate(k)=Ve...In this paper, compression LS estimate (k) of the regression coefficient B isconsidered when the design matrix present ill-condition in multivariate linear model.The MSE (mean square error)of the estimate(k)=Vec( (k))is less than theMSE of LS estimate β ̄* of the regression coefficient β= Vec(B) by choosing the pa-rameter k. Admissibility , numerical stability and relative efficiency of (k)are proved. The method of determining k value for practical use is also suggested展开更多
In this paper,we set up a grey multivtriable model to predict the HFRS morbidity.Forecasting test results show that this new model is of general use in the prediction Of the disease.It is particularly appropriate for ...In this paper,we set up a grey multivtriable model to predict the HFRS morbidity.Forecasting test results show that this new model is of general use in the prediction Of the disease.It is particularly appropriate for HFRS investigations and controls.展开更多
AIM The purpose of this study was to evaluate the diagnostic value of trefoil factor family 3(TFF3) for the early detection of colorectal cancer(CC). METHODS Serum TFF3 and carcino-embryonic antigen(CEA) were detected...AIM The purpose of this study was to evaluate the diagnostic value of trefoil factor family 3(TFF3) for the early detection of colorectal cancer(CC). METHODS Serum TFF3 and carcino-embryonic antigen(CEA) were detected in 527 individuals, including 115 healthy control(HC), 198 colorectal adenoma(CA), and 214 CC individuals in the training group. RESULTS Serum TFF3 showed no significant correlation with age, gender, or tumor location but showed significant correlation with the tumor stage. Serum TFF3 in the CC group was significantly higher than in the HC or CA group. The AUC values of TFF3 for discriminating between HC and CC and between CA and CC were 0.930(0.903, 0.958) and 0.834(0.796, 0.873). A multivariate model combining TFF3 and CEA was built. Compared to TFF3 or CEA alone, the multivariate model showed significant improvement(P < 0.001). For discriminating between HC and CC, HC and early stage CC, HC and advanced stage CC, CA and CC, CA and early stage CC, and CA and advanced stage CC in the training group, the sensitivities were 92.99%, 91.46%, 93.18%, 73.83%, 76.83%, and 81.82%, and the specificities were 91.30%, 91.30%, 93.91%, 88.38%, 77.27%, and 88.38%, respectively. After validation, the sensitivities were 89.39%, 85.71%, 90.79%, 72.73%, 71.43%, and 78.95%, and the specificities were 87.85%, 87.85%, 2.52%, 87.85%, 80.77%, and 87.50%, respectively. CONCLUSION The multivariate diagnostic model that included TFF3 and CEA showed significant improvement over the conventional biomarker CEA and might provide a potential method for the early detection of CC.展开更多
Heavy metal pollution in soil-plant system is of major environmental concern on a world scale and in China in particular with the rapid development of industry. The heavy metal pollution status in soil-plant system in...Heavy metal pollution in soil-plant system is of major environmental concern on a world scale and in China in particular with the rapid development of industry. The heavy metal pollution status in soil-plant system in China, the research progress on the bioavailability of heavy metals (affecting factors, extraction methods, free-ion activity model, adsorption model, multivariate regression model, Q-I relationship, and compound pollution), and soil remediation are reviewed in the paper. Future research and monitoring is also discussed.展开更多
With the likely future of autonomous vehicles(AVs)as private,ride-hailing,and pooled vehicles,it is important to consider all forms of AVs when estimating the impacts of automation on travel behavior.To aid this,this ...With the likely future of autonomous vehicles(AVs)as private,ride-hailing,and pooled vehicles,it is important to consider all forms of AVs when estimating the impacts of automation on travel behavior.To aid this,this study jointly models the public interest in three forms of AVs(owning,ride-hailing,and using pooled services)and compares the interests in owning versus ride-hailing AVs using a combination of structural equation modeling and multivariate ordered probit modeling frameworks.Using the 2019 California Vehicle Survey data,we estimate the impacts of several exogenous and latent variables on all forms of AV adoption.We find that the individual,household,travel-related,and built-environment factors are related to different forms of AV adoption directly and indirectly through attitudes toward human and automated driving.We also report that human and automated driving sentiments have the highest impact on interest in owning an AV compared to interest in ride-hailing and using pooled AVs.We discuss several policy implications by calculating the pseudo-elasticity effects of exogenous variables and the sensitivities of the impacts on latent variables on different forms of AV adoption.For example,public interest in owning private AVs can be increased by more than 7%by making them familiar with autonomous technology.展开更多
In this paper,we consider the admissibility for nonhomogeneous linear estimates on regression coefficients and parameters in multivariate random effect linear model and give eight definitions of different forms for ad...In this paper,we consider the admissibility for nonhomogeneous linear estimates on regression coefficients and parameters in multivariate random effect linear model and give eight definitions of different forms for admissibility. We not only prove that they can be divided into three identical subclasses,but also gain three kinds of necessary and sufficient conditions.展开更多
Von Rosen (1989) proposed the MLE of parameters in multivariate linear normal model MLNM(sumfromn= lto ∞AiBiCi). This paper discusses some properties of Rosen's MLE for general distributions which includs invaria...Von Rosen (1989) proposed the MLE of parameters in multivariate linear normal model MLNM(sumfromn= lto ∞AiBiCi). This paper discusses some properties of Rosen's MLE for general distributions which includs invariant, equivariant, strong consistency and asymptotic normality. Furthermore, we can construct the consistent confidence region for the parameter of experctation in MLNM(sumfromn=1to∞, AiBiCi) and obtain asymptotic distribu- tion and consistent confidence region of the linear discrimination function for canonical correlation by Kahtri (1988).展开更多
Current univariate approach to predict the probability of well construction time has limited accuracy due to the fact that it ignores key factors affecting the time.In this study,we propose a multivariate probabilisti...Current univariate approach to predict the probability of well construction time has limited accuracy due to the fact that it ignores key factors affecting the time.In this study,we propose a multivariate probabilistic approach to predict the risks of well construction time.It takes advantage of an extended multi-dimensional Bernacchia–Pigolotti kernel density estimation technique and combines probability distributions by means of Monte-Carlo simulations to establish a depth-dependent probabilistic model.This method is applied to predict the durations of drilling phases of 192 wells,most of which are located in the AustraliaAsia region.Despite the challenge of gappy records,our model shows an excellent statistical agreement with the observed data.Our results suggested that the total time is longer than the trouble-free time by at least 4 days,and at most 12 days within the 10%–90% confidence interval.This model allows us to derive the likelihoods of duration for each phase at a certain depth and to generate inputs for training data-driven models,facilitating evaluation and prediction of the risks of an entire drilling operation.展开更多
This article presented a new data fusion approach for reasonably predicting dynamic serviceability reliability of the long-span bridge girder.Firstly,multivariate Bayesian dynamic linear model(MBDLM)considering dynami...This article presented a new data fusion approach for reasonably predicting dynamic serviceability reliability of the long-span bridge girder.Firstly,multivariate Bayesian dynamic linear model(MBDLM)considering dynamic correlation among the multiple variables is provided to predict dynamic extreme deflections;secondly,with the proposed MBDLM,the dynamic correlation coefficients between any two performance functions can be predicted;finally,based on MBDLM and Gaussian copula technique,a new data fusion method is given to predict the serviceability reliability of the long-span bridge girder,and the monitoring extreme deflection data from an actual bridge is provided to illustrated the feasibility and application of the proposed method.展开更多
Background and aims:The holistic definition of health is not merely the absence of disease or infirmity,but a state of complete physical,mental,and social well-being.However,related research on the influencing factor ...Background and aims:The holistic definition of health is not merely the absence of disease or infirmity,but a state of complete physical,mental,and social well-being.However,related research on the influencing factor of self-rated health and happiness have generally remained separate.Therefore,this study aimed to 1)find individual level determinants of the two facets of health;and 2)investigate the covariance of the two facets of health within individual levels.Methods:Multivariate multilevel analysis of self-rated health and happiness at level 1,were nested within 10,968 people at level 2.Data were obtained from the 2015 Chinese General Social Survey.Results:Lower happiness and self-rated health were found in 1)females;2)the elderly;3)people with a lower educational level;4)people who were presently single;5)people with a lower self-rated economic status;6)people who resided in urban areas;and 7)people with sedentary lifestyles as compared to those in other categories of the same variable.After adjusting the related individual level determinants,the correlation coefficient of two facets of health at the individual level is 0.19,which indicates that no robust covariance was observed.Conclusions:The current study indicates the existence of disparity in the subjective physical and psychological dimensions of health among the elderly in China.Our findings emphasize the importance of paying attention to different aspects of health simultaneously in investigations and the benefits of leisure time activities.展开更多
文摘This study investigates the factors that impact farmers'adoption of risk management strategies(RMS)in Pakistan during times of uncertainty.The study examines farmers'adoption of RMS using both multinomial probit(MNP)and multivariate probit(MVP).Data were collected from 382 farmers sampled from four districts in KhyberPakhtunkhwa(KP)province of Pakistan via a multistage sampling technique.This study utilizes the MNP model,considering the assumption of Independence of Irrelevant Alternatives(IIA)and incorporating correlated error terms.The objective is to understand farmers'behavior in risky situations and determine if there is heterogeneity.Results are compared with the MVP model to assess robustness and gain deeper understanding of farmers'decisionmaking processes.The research findings reveal that our results are robust,and farmers behave homogeneously in various RMS scenarios.Farmers adopt RMS individually or in combination to mitigate the adverse effects of natural calamities on their livelihood.The risk-averse farmers,who perceive weather-related risks as a threat,access credits and information,and have farms close to a river are more likely to adopt RMS,irrespective of the format of the strategies available.Moreover,the predicted probabilities and correlation of the RMS and RM categories have strengthened our model estimation.These findings provide insights into the behavior of farmers in adopting RMS which are helpful for policymakers and stakeholders in developing strategies to mitigate the impacts of natural calamities on farmers.
基金Sponsored by National Natural Science Foundation of China(61290323,61333007,614730646)IAPI Fundamental Research Funds(2013ZCX02-09)+1 种基金Fundamental Research Funds for the Central Universities of China(N130508002,N130108001)National High-tech Research and Development Program of China(2015AA043802)
文摘Blast furnace (BF) ironmaking process has complex and nonlinear dynamic characteristics. The molten iron temperature (MIT) as well as Si, P and S contents of molten iron is difficult to be directly measured online, and large-time delay exists in offline analysis through laboratory sampling. A nonlinear multivariate intelligent modeling method was proposed for molten iron quality (MIQ) based on principal component analysis (PCA) and dynamic ge- netic neural network. The modeling method used the practical data processed by PCA dimension reduction as inputs of the dynamic artificial neural network (ANN). A dynamic feedback link was introduced to produce a dynamic neu- ral network on the basis of traditional back propagation ANN. The proposed model improved the dynamic adaptabili- ty of networks and solved the strong fluctuation and resistance problem in a nonlinear dynamic system. Moreover, a new hybrid training method was presented where adaptive genetic algorithms (AGA) and ANN were integrated, which could improve network convergence speed and avoid network into local minima. The proposed method made it easier for operators to understand the inside status of blast furnace and offered real-time and reliable feedback infor- mation for realizing close-loop control for MIQ. Industrial experiments were made through the proposed model based on data collected from a practical steel company. The accuracy could meet the requirements of actual operation.
基金supported by the National Natural Science Foundation of China (51479151,61403288)。
文摘Most of the existing multivariable grey models are based on the 1-order derivative and 1-order accumulation, which makes the parameters unable to be adjusted according to the data characteristics of the actual problems. The results about fractional derivative multivariable grey models are very few at present. In this paper, a multivariable Caputo fractional derivative grey model with convolution integral CFGMC(q, N) is proposed. First, the Caputo fractional difference is used to discretize the model, and the least square method is used to solve the parameters. The orders of accumulations and differential equations are determined by using particle swarm optimization(PSO). Then, the analytical solution of the model is obtained by using the Laplace transform, and the convergence and divergence of series in analytical solutions are also discussed. Finally, the CFGMC(q, N) model is used to predict the municipal solid waste(MSW). Compared with other competition models, the model has the best prediction effect. This study enriches the model form of the multivariable grey model, expands the scope of application, and provides a new idea for the development of fractional derivative grey model.
文摘Artemisinins tested against W-2 strains of malaria falciparum are investigated with molecular electrostatic potential (MEP), in an attempt to identify key features of the compounds that are necessary for their activities, as well as to investigate likely interactions with the receptor in a biological process and to use that information to propose new molecules. In order to discover the best geometry involving the ligand-receptor complexes (heme) studied and help in the proposition of the new derivatives, molecular simulations of interactions between the most negative charged region around the peroxide and heme locates (the ones around the Fe2+ ion) were carried out. In addition, PCA (principal components analysis), HCA (hierarchical cluster analysis), SDA (stepwise discriminant analysis), and KNN (K-nearest neighbor) multivariate models were employed to investigate which descriptors are responsible for the classification between the higher and lower antimalarial activity of the compounds, and also this information was used to propose new potentially active molecules. The information accumulated in studies of MEP, molecular docking, and multivariate analysis supported the proposal of new structures with potential antimalarial activities. The multivariate models constructed were applied to the new structures and indicated numbers 19 and 20 as the most prominent for syntheses and biological assays.
基金Supported by the Digestive Medical Coordinated Development Center of Beijing Municipal Administration,No.XXZ0403.
文摘BACKGROUNDSpontaneous bacterial peritonitis (SBP) is a detrimental infection of the asciticfluid in liver cirrhosis patients, with high mortality and morbidity. Earlydiagnosis and timely antibiotic administration have successfully decreased themortality rate to 20%-25%. However, many patients cannot be diagnosed in theearly stages due to the absence of classical SBP symptoms. Early diagnosis ofasymptomatic SBP remains a great challenge in the clinic.AIMTo establish a multivariate predictive model for early diagnosis of asymptomaticSBP using positive microbial cultures from liver cirrhosis patients with ascites.METHODSA total of 98 asymptomatic SBP patients and 98 ascites liver cirrhosis patients withnegative microbial cultures were included in the case and control groups,respectively. Multiple linear stepwise regression analysis was performed toidentify potential indicators for asymptomatic SBP diagnosis. The diagnosticperformance of the model was estimated using the receiver operatingcharacteristic curve.RESULTSPatients in the case group were more likely to have advanced disease stages,cirrhosis related-complications, worsened hematology and ascites, and higher mortality. Based on multivariate analysis, the predictive model was as follows: y (P) = 0.018 + 0.312 × MELD (model of end-stage liver disease) + 0.263 × PMN(ascites polymorphonuclear) + 0.184 × N (blood neutrophil percentage) + 0.233 ×HCC (hepatocellular carcinoma) + 0.189 × renal dysfunction. The area under thecurve value of the established model was 0.872, revealing its high diagnosticpotential. The diagnostic sensitivity was 73.5% (72/98), the specificity was 86.7%(85/98), and the diagnostic efficacy was 80.1%.CONCLUSIONOur predictive model is based on the MELD score, polymorphonuclear cells,blood N, hepatocellular carcinoma, and renal dysfunction. This model mayimprove the early diagnosis of asymptomatic SBP.
基金Funding from The Scientific and Technological Research Council of Turkey(Project No:2130026)is gratefully acknowledged
文摘Background: Leaf Area Index(LAI) is an important parameter used in monitoring and modeling of forest ecosystems. The aim of this study was to evaluate performance of the artificial neural network(ANN) models to predict the LAI by comparing the regression analysis models as the classical method in these pure and even-aged Crimean pine forest stands.Methods: One hundred eight temporary sample plots were collected from Crimean pine forest stands to estimate stand parameters. Each sample plot was imaged with hemispherical photographs to detect the LAI. The partial correlation analysis was used to assess the relationships between the stand LAI values and stand parameters, and the multivariate linear regression analysis was used to predict the LAI from stand parameters. Different artificial neural network models comprising different number of neuron and transfer functions were trained and used to predict the LAI of forest stands.Results: The correlation coefficients between LAI and stand parameters(stand number of trees, basal area, the quadratic mean diameter, stand density and stand age) were significant at the level of 0.01. The stand age, number of trees, site index, and basal area were independent parameters in the most successful regression model predicted LAI values using stand parameters(R_(adj)~2=0.5431). As corresponding method to predict the interactions between the stand LAI values and stand parameters, the neural network architecture based on the RBF 4-19-1 with Gaussian activation function in hidden layer and the identity activation function in output layer performed better in predicting LAI(SSE(12.1040), MSE(0.1223), RMSE(0.3497), AIC(0.1040), BIC(-77.7310) and R^2(0.6392)) compared to the other studied techniques.Conclusion: The ANN outperformed the multivariate regression techniques in predicting LAI from stand parameters. The ANN models, developed in this study, may aid in making forest management planning in study forest stands.
基金Supported by the Anhui Provincial Natural Science Foundation(11040606M04) Supported by the National Natural Science Foundation of China(10871001,10971097)
文摘The paper considers a multivariate partially linear model under independent errors,and investigates the asymptotic bias and variance-covariance for parametric component βand nonparametric component F(·)by the GJS estimator and Kernel estimation.
文摘The reservoir volumetric approach represents a widely accepted, but flawed method of petroleum play resource calculation. In this paper, we propose a combination of techniques that can improve the applicability and quality of the resource estimation. These techniques include: 1) the use of the Multivariate Discovery Process model (MDP) to derive unbiased distribution parameters of reservoir volumetric variables and to reveal correlations among the variables; 2) the use of the Geo-anchored method to estimate simultaneously the number of oil and gas pools in the same play; and 3) the crossvalidation of assessment results from different methods. These techniques are illustrated by using an example of crude oil and natural gas resource assessment of the Sverdrup Basin, Canadian Archipelago. The example shows that when direct volumetric measurements of the untested prospects are not available, the MDP model can help derive unbiased estimates of the distribution parameters by using information from the discovered oil and gas accumulations. It also shows that an estimation of the number of oil and gas accumulations and associated size ranges from a discovery process model can provide an alternative and efficient approach when inadequate geological data hinder the estimation. Cross-examination of assessment results derived using different methods allows one to focus on and analyze the causes for the major differences, thus providing a more reliable assessment outcome.
文摘For multivariate linear model Y=XΘ+ε, ~N(0, σ 2ΣV), this paper is concerned with the admissibility of linear estimators of estimable function SXΘ in the class of all estimators. All admissible linear estimators of SXΘ are given under each of four definitions of admissibility.
文摘Considering the problems that should be solved in the synthetic earthquake prediction at present, a new model is proposed in the paper. It is called joint multivariate statistical model combined by principal component analysis with discriminatory analysis. Principal component analysis and discriminatory analysis are very important theories in multivariate statistical analysis that has developed quickly in the late thirty years. By means of maximization information method, we choose several earthquake prediction factors whose cumulative proportions of total sam-ple variances are beyond 90% from numerous earthquake prediction factors. The paper applies regression analysis and Mahalanobis discrimination to extrapolating synthetic prediction. Furthermore, we use this model to charac-terize and predict earthquakes in North China (30~42N, 108~125E) and better prediction results are obtained.
文摘In this paper, compression LS estimate (k) of the regression coefficient B isconsidered when the design matrix present ill-condition in multivariate linear model.The MSE (mean square error)of the estimate(k)=Vec( (k))is less than theMSE of LS estimate β ̄* of the regression coefficient β= Vec(B) by choosing the pa-rameter k. Admissibility , numerical stability and relative efficiency of (k)are proved. The method of determining k value for practical use is also suggested
文摘In this paper,we set up a grey multivtriable model to predict the HFRS morbidity.Forecasting test results show that this new model is of general use in the prediction Of the disease.It is particularly appropriate for HFRS investigations and controls.
基金Supported by The Capital Health Development Special Scientific Research Projects,No.2014-2-2154National Natural Science Foundation of China,No.81471761 and No.81501568
文摘AIM The purpose of this study was to evaluate the diagnostic value of trefoil factor family 3(TFF3) for the early detection of colorectal cancer(CC). METHODS Serum TFF3 and carcino-embryonic antigen(CEA) were detected in 527 individuals, including 115 healthy control(HC), 198 colorectal adenoma(CA), and 214 CC individuals in the training group. RESULTS Serum TFF3 showed no significant correlation with age, gender, or tumor location but showed significant correlation with the tumor stage. Serum TFF3 in the CC group was significantly higher than in the HC or CA group. The AUC values of TFF3 for discriminating between HC and CC and between CA and CC were 0.930(0.903, 0.958) and 0.834(0.796, 0.873). A multivariate model combining TFF3 and CEA was built. Compared to TFF3 or CEA alone, the multivariate model showed significant improvement(P < 0.001). For discriminating between HC and CC, HC and early stage CC, HC and advanced stage CC, CA and CC, CA and early stage CC, and CA and advanced stage CC in the training group, the sensitivities were 92.99%, 91.46%, 93.18%, 73.83%, 76.83%, and 81.82%, and the specificities were 91.30%, 91.30%, 93.91%, 88.38%, 77.27%, and 88.38%, respectively. After validation, the sensitivities were 89.39%, 85.71%, 90.79%, 72.73%, 71.43%, and 78.95%, and the specificities were 87.85%, 87.85%, 2.52%, 87.85%, 80.77%, and 87.50%, respectively. CONCLUSION The multivariate diagnostic model that included TFF3 and CEA showed significant improvement over the conventional biomarker CEA and might provide a potential method for the early detection of CC.
文摘Heavy metal pollution in soil-plant system is of major environmental concern on a world scale and in China in particular with the rapid development of industry. The heavy metal pollution status in soil-plant system in China, the research progress on the bioavailability of heavy metals (affecting factors, extraction methods, free-ion activity model, adsorption model, multivariate regression model, Q-I relationship, and compound pollution), and soil remediation are reviewed in the paper. Future research and monitoring is also discussed.
文摘With the likely future of autonomous vehicles(AVs)as private,ride-hailing,and pooled vehicles,it is important to consider all forms of AVs when estimating the impacts of automation on travel behavior.To aid this,this study jointly models the public interest in three forms of AVs(owning,ride-hailing,and using pooled services)and compares the interests in owning versus ride-hailing AVs using a combination of structural equation modeling and multivariate ordered probit modeling frameworks.Using the 2019 California Vehicle Survey data,we estimate the impacts of several exogenous and latent variables on all forms of AV adoption.We find that the individual,household,travel-related,and built-environment factors are related to different forms of AV adoption directly and indirectly through attitudes toward human and automated driving.We also report that human and automated driving sentiments have the highest impact on interest in owning an AV compared to interest in ride-hailing and using pooled AVs.We discuss several policy implications by calculating the pseudo-elasticity effects of exogenous variables and the sensitivities of the impacts on latent variables on different forms of AV adoption.For example,public interest in owning private AVs can be increased by more than 7%by making them familiar with autonomous technology.
文摘In this paper,we consider the admissibility for nonhomogeneous linear estimates on regression coefficients and parameters in multivariate random effect linear model and give eight definitions of different forms for admissibility. We not only prove that they can be divided into three identical subclasses,but also gain three kinds of necessary and sufficient conditions.
文摘Von Rosen (1989) proposed the MLE of parameters in multivariate linear normal model MLNM(sumfromn= lto ∞AiBiCi). This paper discusses some properties of Rosen's MLE for general distributions which includs invariant, equivariant, strong consistency and asymptotic normality. Furthermore, we can construct the consistent confidence region for the parameter of experctation in MLNM(sumfromn=1to∞, AiBiCi) and obtain asymptotic distribu- tion and consistent confidence region of the linear discrimination function for canonical correlation by Kahtri (1988).
文摘Current univariate approach to predict the probability of well construction time has limited accuracy due to the fact that it ignores key factors affecting the time.In this study,we propose a multivariate probabilistic approach to predict the risks of well construction time.It takes advantage of an extended multi-dimensional Bernacchia–Pigolotti kernel density estimation technique and combines probability distributions by means of Monte-Carlo simulations to establish a depth-dependent probabilistic model.This method is applied to predict the durations of drilling phases of 192 wells,most of which are located in the AustraliaAsia region.Despite the challenge of gappy records,our model shows an excellent statistical agreement with the observed data.Our results suggested that the total time is longer than the trouble-free time by at least 4 days,and at most 12 days within the 10%–90% confidence interval.This model allows us to derive the likelihoods of duration for each phase at a certain depth and to generate inputs for training data-driven models,facilitating evaluation and prediction of the risks of an entire drilling operation.
基金This work was supported by Natural Science Foundation of Gansu Province of China(20JR10RA625,20JR10RA623)National Key Research and Development Project of China(Project No.2019YFC1511005)+1 种基金Fundamental Research Funds for the Central Universities(Grant No.lzujbky-2020-55)National Natural Science Foundation of China(Grant No.51608243).
文摘This article presented a new data fusion approach for reasonably predicting dynamic serviceability reliability of the long-span bridge girder.Firstly,multivariate Bayesian dynamic linear model(MBDLM)considering dynamic correlation among the multiple variables is provided to predict dynamic extreme deflections;secondly,with the proposed MBDLM,the dynamic correlation coefficients between any two performance functions can be predicted;finally,based on MBDLM and Gaussian copula technique,a new data fusion method is given to predict the serviceability reliability of the long-span bridge girder,and the monitoring extreme deflection data from an actual bridge is provided to illustrated the feasibility and application of the proposed method.
文摘Background and aims:The holistic definition of health is not merely the absence of disease or infirmity,but a state of complete physical,mental,and social well-being.However,related research on the influencing factor of self-rated health and happiness have generally remained separate.Therefore,this study aimed to 1)find individual level determinants of the two facets of health;and 2)investigate the covariance of the two facets of health within individual levels.Methods:Multivariate multilevel analysis of self-rated health and happiness at level 1,were nested within 10,968 people at level 2.Data were obtained from the 2015 Chinese General Social Survey.Results:Lower happiness and self-rated health were found in 1)females;2)the elderly;3)people with a lower educational level;4)people who were presently single;5)people with a lower self-rated economic status;6)people who resided in urban areas;and 7)people with sedentary lifestyles as compared to those in other categories of the same variable.After adjusting the related individual level determinants,the correlation coefficient of two facets of health at the individual level is 0.19,which indicates that no robust covariance was observed.Conclusions:The current study indicates the existence of disparity in the subjective physical and psychological dimensions of health among the elderly in China.Our findings emphasize the importance of paying attention to different aspects of health simultaneously in investigations and the benefits of leisure time activities.