Effect of organic mineral supplementation in reducing oxidative stress in Holstein calves during short‑term heat stress and recovery conditions

Background This study investigated the effects of inorganic and organic minerals on physiological responses,oxidative stress reduction,and rumen microbiota in Holstein bull calves(123.81±9.76 kg;5 months old)during short-term heat stress(HS)and recovery periods.Eight Holstein calves were randomly assigned to four treatment groups:no mineral supplementation(Con),inorganic minerals(IM),organic minerals(OM),and high-concentration organic minerals(HOM)and two thermal environments(HS and recovery)using 4×2 factorial arrangement in a crossover design of four periods of 35 d.Calves were maintained in a temperature-controlled barn.The experimental period consisted of 14 d of HS,14 d of recovery condititon,and a 7-d washing period.Results Body temperature and respiration rate were higher in HS than in the recovery conditions(P<0.05).Selenium concentration in serum was high in the HOM-supplemented calves in both HS(90.38μg/dL)and recovery periods(102.00μg/dL)(P<0.05).During the HS period,the serum cortisol was 20.26 ng/mL in the HOM group,which was 5.60 ng/mL lower than in the control group(P<0.05).The total antioxidant status was the highest in the OM group(2.71 mmol Trolox equivalent/L),followed by the HOM group during HS,whereas it was highest in the HOM group(2.58 mmol Trolox equivalent/L)during the recovery period(P<0.05).Plasma malondialdehyde and HSP70 levels were decreased by HOM supplementation during the HS and recovery periods,whereas SOD and GPX levels were not significantly affected(P>0.05).The principal coordinate analysis represented that the overall rumen microbiota was not influenced by mineral supplementation;however,temperature-induced microbial structure shifts were indicated(PERMANOVA:P<0.05).At the phylum level,Firmicutes and Actinobacteria decreased,whereas Fibrobacteres,Spirochaetes,and Tenericutes increased(P<0.05),under HS conditions.The genus Treponema increased under HS conditions,while Christensenella was higher in recovery conditions(P<0.05).Conclusion HOM supplementation during HS reduced cortisol concentrations and increased total antioxidant status in Holstein bull calves,suggesting that high organic mineral supplementation may alleviate the adverse effects of HS.

Synthesis of highly fluorescent carbon dots from lemon and onion juices for determination of riboflavin in multivitamin/mineral supplements

In this work, lemon and onion biomasses commonly found in street markets are for the first time used to develop a facile, fast and low-cost one-step microwave-assisted carbonization method for synthesis of highly fluorescent carbon dots (CDs). The structure and optical properties of CDs were investigated by TEM, XRD, XRF, UV-Vis, FTIR, and fluorescence spectroscopy. CDs displayed satisfactory optical pro-prieties, a high quantum yield of 23.6%, and excellent water solubility, and the particle size was 4.23-8.22 nm with an average diameter of 6.15 nm. An efficient fluorescent resonance energy transfer (FRET) between the CDs and riboflavin was achieved with CDs acting as donor and riboflavin as acceptor. A linear relationship between FRET and the riboflavin concentration from 0.10 to 3.0 μg/mL was observed, allowing the development of an accurate and fast analytical method to determine this vitamin in multivitamin/mineral supplements. Despite the potential interferences in these supplements, CDs were selective for riboflavin under optimized conditions. A paired t-test at a 95% confidence level indicated no statistically significant difference between the proposed and the reference methods. Recovery test presented values ranged from 96.0% to 101.4%. The limit of detection and relative standard deviation were estimated at 1.0 ng/mL and <2.6% (n = 3), respectively. CDs were successfully synthesized in a domestic microwave oven (1450 W, 6 min), presenting satisfactory parameters when compared with results of other studies reported in the literature, suggesting that the proposed method is a potentially useful method for the synthesis of CDs and determination of riboflavin.

Mineral Intake in Urban Pregnant Women from Base Diet,Fortified Foods,and Food Supplements:Focus on Calcium,Iron,and Zinc

In the Chinese national nutrition surveys, fortified foods were not investigated separately from the base diet, and the contribution of fortified foods to micronutrients intake is not very clear. This study investigated the diet, including fortified foods and food supplements, of urban pregnant women and analyzed the intake of calcium, iron,and zinc to assess the corresponding contributions of fortified foods, food supplements, and the base diet. The results demonstrated that the base diet was the major source of calcium, iron, and zinc, and was recommended to be the first choice for micronutrients intake. Furthermore, consumption of fortified foods and food supplements offered effective approaches to improve the dietary intake of calcium, iron, and zinc in Chinese urban pregnant women.

Intake of Minerals from Food Supplements in a German Population—A Nationwide Survey

Introduction: Studies indicate that 17.9% - 60% of adults in Germany and Europe regularly use food supplements. Some reports suggest that their use might be responsible for excessive nutrient intake. The purpose of this survey was to examine the quantitative mineral intakes from food supplements: whether the tolerable upper intake levels (ULs) with supplements alone, or in combination with food was exceeded was checked. Methods: The survey was carried out by the Association for Consumer Research, Nürnberg, Germany. Anonymous data of 1070 supplement users (40.8% men, 59.2% women) aged 18 - 93 years were available. Three groups were examined based on dietary and supplemental mineral intakes: average, middle-high and high intake. Results: The mean number of supplements reported was 1.6 ± 1.1 products in men and 1.5 ± 0.9 products in women. The minerals most frequently consumed were magnesium, followed by calcium, zinc and selenium. The percentage of the supplement users with total intakes greater than the UL was minimal for all minerals. Supplement use in 143 cases increased the likelihood of intakes above the UL only for magnesium. Subjects particularly in the high intake group—as a worst case scenario—had intakes above the UL in the case of calcium (n = 23) and zinc (n = 34). The percentage of subjects taking several products was greater in subjects exceeding the UL than in those below (P < 0.001). Multiple use was seen significantly more often in men than in women (P < 0.01). Conclusions: In this survey, supplement use was generally not associated with excessive intake. Supplement use resulted in intakes above the UL in only a few cases relating to magnesium, calcium and zinc. This applies more often to elderly subjects and particularly to those who already have a high mineral intake from food in the model calculation.

Effects of Lemon Beverages on Bone Metabolism and Bone Mineral Density in Postmenopausal Women: A Double-Blind, Controlled Intervention Study with Ca-Supplemented and Unsupplemented Lemon Beverages

The aim of the present study was to elucidate how bone metabolism and bone mineral density are affected by the consumption of a lemon juice-containing calcium (Ca)-enriched beverage. The efficacy of this investigational product was evaluated in postmenopausal women during five months of continuous intake (intervention). This was a randomized, controlled trial. Eighty-three subjects were assigned to three groups. Using a double-blind format, the first two groups received a Ca-supplemented lemon-juice (lemon) beverage (LECA) or a Ca-unsupplemented lemon-juice (lemon) beverage (LE). The third group (control) received no intervention. Each subject in the LECA and LE groups consumed one bottle (290 mL) of their assigned investigational product every day for five consecutive months. After five months of intervention, the gain in bone mineral density at the lumbar spine was significantly larger in the LECA and LE groups than in the control group. In the femur, subjects in the LECA group gained significantly more bone mineral density than the control subjects. The largest gain in bone mineral density at the lumbar spine was observed in the LECA group. As for the concentrations of the bone resorption marker tartrate-resistant acid phosphatase 5b (TRACP-5b), subjects in the LECA group had significantly lower values than those in the control group. Similarly, when compared with the LE and control groups, a significant decrease was detected in the LECA group in the concentrations of the bone formation markers, bone alkaline phosphatase (BAP) and osteocalcin (OC). In postmenopausal women, continuous consumption of Ca-supplemented lemon beverages improved the absorption of Ca and inhibited bone resorption. This likely blocked the function of osteoblasts and led to the suppression of bone formation, resulting in the attenuation of high-turnover bone metabolism.

Change of BMD after Weaning or Resumption of Menstruation in Chinese Women with Different FokI VDR-genotypes:A Randomized,Placebo-controlled,Calcium Supplementation Trial

Objective To investigate the effect of calcium supplementation on bone mineral density （BMD） in Chinese women with different Fokl vitamin D receptor （VDR） genotypes （FF, Ff, and ff） after weaning or resumption of menstruation during lactation. Methods A total of 40 subjects with the same Fokl VDR genotype were randomly divided into two groups： one received calcium tablet （600 mg once daily as CaCO3） and the other placebo tablet once daily for 1 year. At baseline, BMD was measured by dual-energy X-ray absorptiometry at lumbar spine （L2-L4） and at left hip whereas serum PICP, serum OC, and urinary CTX, serum 25（OH）VitD3, and serum estradiol were measured at weaning and I year thereafter. Results After the intervention, BMD at lumbar spine and at left hip increased significantly in all these women with a trend among different Fokl VDR genotypes such as FF 〉 Ff 〉 ff （P〈O.05, 〈0.01, and 〈0.001, respectively）. BMD at lumbar spine in women with FF VDR genotype increased much more rapidly than in those with ff VDR genotype （P〈0.05）. Compared with the control group women with the FF genotype regained more BMD after calcium supplementation （P〈0.05）. Conclusion Daily calcium 600 mg supplementation has beneficial effect on the bone health of women with FF VDR genotype.

高剂量维生素D补充剂对绝经后骨质疏松症患者骨代谢标志物、骨密度的影响

目的探究高剂量维生素D补充剂对绝经后骨质疏松症患者骨代谢标志物、骨密度的影响。方法选取2021年2月至2022年2月淄博市临淄区妇幼保健院(齐都医院)妇科治疗的120例绝经后骨质疏松症患者作为研究对象,按照随机数字表法分为对照组(60例)和观察组(60例)。对照组采用口服维生素D治疗,观察组在对照组基础上注射维生素D针剂治疗,比较两组骨代谢标志物和骨密度。结果观察组治疗3、6、12个月后血清Ⅰ型胶原羧基端肽β特殊序列、Ⅰ型前胶原氨基端肽水平均低于对照组(P<0.05);观察组各部位骨密度均高于对照组(P<0.05)。结论绝经后骨质疏松症患者补充高剂量维生素D可有效减少体内的骨量流失,改善骨代谢水平,提高骨密度。

关于口服多维元素制剂质量研究的一些考虑

口服多维元素制剂为多种维生素和矿物质组成的复方制剂,鉴于该类品种处方组成较为复杂,质量研究的方法需要进一步探索和提升。本文结合品种特点、审评经验和现行国内外的法规要求提出一些考虑,旨在为此类品种后续的研发提供一些参考。

养元健骨汤联合常规补钙对老年股骨粗隆间骨折髓内钉术后患者骨密度及骨折愈合速度的影响

目的 探讨养元健骨汤联合常规补钙对老年股骨粗隆间骨折髓内钉术后患者骨密度及骨折愈合速度的影响。方法 选取医院2018年1月至2022年2月收治的老年股骨粗隆间骨折行髓内钉术的患者90例,按随机数字表法分为常规补钙组和养元健骨汤组,各45例。两组患者术后均予常规补钙治疗,养元健骨汤组患者加用养元健骨汤,均持续治疗1个月。结果 养元健骨汤组总有效率为93.33%,显著高于常规补钙组的73.33%(P <0.05)。治疗后,两组患者的骨代谢指标β胶联降解产物含量均显著减少(P <0.05),Ⅰ型胶原氨基端肽原、血清骨钙素含量均显著增加(P <0.05),且养元健骨汤组均显著优于常规补钙组(P <0.05);两组患者的Harris髋关节功能评分量表(HHS)评分、骨密度均显著升高(P <0.05),且养元健骨汤组均显著高于常规补钙组(P <0.05);养元健骨汤组患者的股骨骨折愈合时间显著短于常规补钙组(P <0.05)。养元健骨汤组和常规补钙组不良反应发生率相当(6.67%比4.44%,P> 0.05)。结论 养元健骨汤联合常规补钙治疗老年股骨粗隆间骨折髓内钉术后的临床疗效良好,能增加患者的骨密度,加快骨折愈合速度,且安全性良好。

Supplemental mineral ions for bone regeneration and osteoporosis treatment

Mineral ions play a crucial role in various biological processes in the human body,particularly in bone repair and regeneration.Supplementation with mineral ions offers several advantages over other therapies or treatments for bone repair and regeneration,such as higher biosafety,universal applicability,and compatibility with the immune system.Additionally,supplementation with mineral ions may avoid the need for invasive surgical procedures.The aim of this review is to provide a comprehensive overview of the functions of potentially beneficial mineral ions and their effects on bone regeneration and osteoporosis treatment.By examining previous studies,including in vitro cellular experiments,in vivo animal models,and clinical trials,this review compares the benefits and potential adverse effects of these mineral ions.Moreover,the review provides guidelines for suggested daily supplementation of these mineral ions to assist future preclinical and clinical studies in bone regeneration and osteoporosis treatment.

金龙蛤蚧平喘加味方对COPD稳定期合并骨质疏松患者骨密度和骨代谢生化标志物的影响

目的:观察金龙蛤蚧平喘加味方对慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)稳定期肺肾气虚证合并骨质疏松患者骨密度(bone mineral density,BMD)及骨代谢生化标志物的影响。方法:选取2022年9月至2023年8月安徽中医药大学附属滁州中西医结合医院呼吸科门诊及病房收治的COPD稳定期肺肾气虚证合并OP患者58例,根据随机数字表法分为对照组和联合组,每组29例。对照组给予常规西药对症治疗,联合组在对照组治疗的基础上联合金龙蛤蚧平喘加味方治疗。观察两组患者治疗前后肺功能[1秒用力呼气容积(forced expiratory volume in one second,FEV1)用力肺活量(forced vital capacity,FVC)、FEV1/FVC]、COPD评估测试问卷(COPD assessment test,CAT)评分、症状积分、BMD及骨代谢生化标志物[总碱性磷酸酶(alkaline phosphatase,ALP)、骨钙素(osteocalcin,OC)及Ⅰ型胶原C端肽(C-terminal peptide of type 1 collagen,CTX-1)]等指标变化情况。结果:联合组治疗后腰椎BMD高于对照组,差异有统计学意义(P<0.05),股骨颈BMD高于对照组,差异无统计学意义(P>0.05);联合组治疗后ALP、OC、CTX-1水平低于对照组,差异有统计学意义(P<0.05);联合组治疗后腰背疼痛、腰膝酸软、下肢抽筋症状积分均低于对照组,差异有统计学意义(P<0.05);联合组治疗后FEV1高于对照组,CAT评分低于对照组,差异有统计学意义(P<0.05)。结论:金龙蛤蚧平喘加味方能改善COPD稳定期肺肾气虚证合并骨质疏松患者的骨密度、肺功能,降低骨代谢生化标志物ALP、OC、CTX-1水平,减轻患者腰背疼痛、腰膝酸软、下肢抽筋症状。

Physico-Chemical and Sensory Evaluation of Wheat Bread Supplemented with Stabilized Undefatted Rice Bran

The effect of rice bran supplementation on some physicochemical and sensory properties of wheat bread was deter mined. Blends of wheat flour and rice bran (95:5, 90:10 and 85:15) were used to bake bread with 100% wheat flour as control. Thereafter, proximate, vitamin and mineral composition, as well as the physical and sensory properties of the dough and bread loaves were determined, using standard methods of analysis. The moisture content, crude protein, crude fat, crude fibre and ash of the composite bread loaves increased significantly (p < 0.05) from 21.07% to 23.67%, 12.04% to 13.10%, 1.57% to 3.77%, 1.76% to 2.91% and 1.46% to 2.41% respectively;while carbohydrate content decreased with increased level of supplementation from 62.10% to 54.14%. There were significant increases (p < 0.05) in vitamin B1 (Thiamin) from 0.15 mg/100g to 0.47 mg/100g and B2 (Niacin) from 3.31 mg/100g to 4.04 mg/100g but no significant increase (p > 0.05) in vitamin B3 (Riboflavin). Mineral content of the bread increased significantly (p < 0.05) with increased level of supplementation from 9.32 mg/100g to 20.52 mg/100g (Iron), 80.74 mg/100g to 188.20 mg/100g (Potassium), 81.31 mg/100g to 130.70 mg/100g (Calcium) and 13.65 mg/100g to 132.22 mg/100g (Magne sium). However, there was a significant decrease (p < 0.05) in sodium with increased level of supplementation from 305.25 mg/100g to 253.03 mg/100g. Bread loaf weight increased from 152.7 g to 162.7 g;while loaf volume decreased from 655.2 ml to 586.0 ml and specific loaf volume decreased from 4.29 ml/g to 3.60 ml/g. There were significant dif ferences (p < 0.05) in physical properties of dough and bread loaves between the composite bread and the control. Though 100% wheat bread had better acceptability scores (7.95) compared to composite bread (7.20 for 95:5 blend), all the composite bread samples had significantly (p < 0.05) higher values for nutritional parameters. There was therefore, a significant improvement in the nutritional composition of the wheat bread with rice bran supplementation.

Effect of a Protein-Energy Supplement of Low Consumption with Coconut Pulp Expeller (<i>Acrocomia aculeata</i>) of Beef Cattle at Pasture

The purpose of this study is to evaluate the effect of a low consumption protein-energy supplement that incorporates 15% of coconut pulp expeller in bovine animals. These pasture fattening cattle were checked on daily weight gain, supplement consumption and efficiency of pasture use. This study was carried out in a livestock establishment in the Department of Concepción, Paraguay. A total of 108 animals were selected;castrated male bovines, 342 ± 30.2 of body weight (BW), age average 28 months, Nelore breed distributed in 2 treatments (T1 and T2): T1 = 42 animals;control group (pasture + conventional mineral salt) and T2 = 66 animals;treatment group with a protein-energy supplement (pasture + protein-energy supplement with minerals). In both treatments, the animals grazed on pasture of Brachiaria brizantha cv. Marandú and Panincum maximaun cv. Tanzania used a system of pasture rotation of 1 - 3 days of occupation and 35 - 40 days of rest. The average daily weight gain (DG) was 0.82 and 0.83 kg/day (p > 0.05), the supplement consumption was 0.1 and 0.28 kg/day per animal and the % disappearance of the biomass of 18 and 23% for T1 and T2, respectively. In conclusion, there was no evident effect on DG of protein-energy

高效液相色谱法测定复合营养素补充剂中叶酸含量

目的:通过建立一种提取效率高、耐复杂基质干扰能力强的样品前处理方式结合高效液相色谱紫外(High performance liquid chromatography-ultraviolet,HPLC-UV)检测方法,解决复合营养素补充剂中叶酸的准确定量检测难题。方法:以多种维生素矿物质片为特征样品,首次采用弱碱性饱和乙二胺四乙酸二钠盐(EDTA)溶液为样品提取液并结合操作简便的超声提取前处理方法,高效提取供试品中的叶酸成分并有效屏蔽基质因素干扰,最终使用HPLC分离高灵敏检测。结果:叶酸在浓度范围0.9912~49.5615μg/mL内保持良好现行关系(r2=0.9999);加标回收率达99.08%;平行试验结果RSD=1.01%(n=6);方法定量限LOQ=0.15μg/mL。改进后的分析方法通过系统的方法学验证后发现能够针对多种维生素矿物质片中的叶酸进行准确定量,并成功应用于市面上多种剂型叶酸类保健食品的实际检测中,结果均与产品标示量保持一致。结论:本方法简便易操作、提取效率高、抗基质干扰能力强、应用范围广,适用于多种维生素矿物质片中的叶酸含量测定,并为复合营养素补充剂类保健食品中叶酸测检测提供了一条新的途径。

高效液相色谱法测定维生素和矿物质复方制剂中维生素K_(2)含量

目的建立测定维生素和矿物质复方制剂中维生素K_(2)(七烯甲萘醌)含量的高效液相色谱法。方法色谱柱为Thermo 30105-154630型ODS柱(150 mm×4.6 mm,5μm),流动相为甲醇,流速为1.0 mL/min,检测波长为254 nm,柱温为50℃,进样量为50μL。结果七烯甲萘醌的质量浓度在0~1.0μg/mL范围内与峰面积线性关系良好(R^(2)=0.9999,n=5);检测限为0.12μg/g,定量限为0.36μg/g;精密度、稳定性试验结果的RSD均小于3%(n=6);平均加样回收率为99.33%,RSD为2.98%(n=9)。结论该方法操作简便、结果准确、稳定性好,可用于维生素和矿物质复方制剂中维生素K_(2)的含量测定。

营养干预对陕西贫困农村学生身心健康的影响研究

通过在陕西省8个贫困县54个样本小学对四年级学生开展随机干预试验,分析了微量营养素干预对贫困农村学生营养、健康和学业表现的影响。文章指出我国贫困农村地区学生存在严重的微量营养素缺乏问题,贫血率高达38.8%,寄宿学生贫血情况比非寄宿学生严重。相对于对照组学生而言,在给微量营养素干预组贫困农村学生每天服用一片21金维他多维元素片,服用半年后学生的血红蛋白水平和标准化数学测试得分都有显著提高,贫血率也有显著的下降,学生的营养、健康和学业表现都有不同程度的改善。建议在农村义务教育学生营养改善计划实施过程中将微量营养素补充纳入项目范畴,以改善贫困农村义务教育学生营养改善计划的实施效果。

北京市成年人膳食及营养补充剂中维生素和矿物质的摄入状况

目的研究膳食营养补充剂对北京市居民维生素和矿物质摄入水平及营养素摄入的影响。方法采用多阶段整群抽样法,抽取北京市6区县1440户家庭,调查18岁及以上成年人3992人。结果男性由膳食提供的维生素和矿物质的平均摄入量均高于女性,但是女性烟酸、维生素C的总摄入量高于男性。使用者的维生素和矿物质的摄入量均高于非使用者,在使用者中,补充剂中硫胺素的贡献率男性为60%,女性为70%,核黄素的贡献率为男性47%,女性45%,钙的贡献率为男性42%,女性为45%。使用者中维生素和矿物质达到或超过参考值的比例明显高于非使用者,特别是维生素C和钙,高出20～30个百分点。结论使用营养补充剂提高了维生素和矿物质的摄入水平,使人群达到参考摄入量的比例增加。今后营养调查中应增加营养补充剂调查,以提高营养素评价的准确度。

高原部队多维元素类营养补充剂研究进展

营养素补充剂是以补充人体所需营养素为目的,由一种或数种经化学合成或从天然动植物中提取的营养素为原料制成的产品,其中维生素和微量元素的补充剂即多维元素类营养补充剂占重要地位。营养补充剂对于营养不良造成的健康问题具有有效的治疗作用。孕妇和在特殊环境中生活工作的人群对营养元素的需求显著高于正常人群,对于他们而言,营养补充剂的作用更为重要。本文在分析目前国内外营养补充剂的应用现状、比较现有不同营养剂配方的基础上,结合我国高原地区的地理状况、气候特点、军民饮食习惯以及营养状况调查分析,阐述适合高原部队作训营养补充剂研发的必要性,为高原部队多维元素类营养补充剂的研究设计和开发应用提供理论依据。

补充多种维生素制剂对动脉硬化性疾病患者同型半胱氨酸水平的影响

目的通过本院干部体检资料的分析,探讨补充多种维生素对血浆同型半胱氨酸(Hcy)及动脉硬化性疾病患病率的影响。方法1999年度本院干部体检1220人和1999年4月～2000年10月部分住院患者358人,共1578人,其中男1403人,女175人;年龄39～99岁,平均(70.32±10.04)岁。空腹抽血并分离血浆,用酶联免疫法测定血浆Hcy浓度,同时调查其是否服用多种维生素和服用年数,以及是否患有动脉硬化性疾病(包括冠心病、缺血性脑卒中、高血压)和糖尿病。结果(1)正常组610人,男536人,女74人(无心、脑、肾疾病史、高血压、糖尿病及血栓性疾病史者);Hcy的血浆水平为(11.71±4.80)μmol/L,男性血浆Hcy水平高于女性,为(11.93±4.91)μmol/Lvs(10.14±3.57)μmol/L,P<0.01。(2)动脉硬化性疾病组968人,Hcy水平明显高于正常组,为(13.68±7.60)μmol/Lvs(11.71±4.80)μmol/L,P<0.01。(3)服用多种维生素者的血浆Hcy水平明显低于未曾服用者,为(11.59±4.84)μmol/Lvs(13.57±7.37)μmol/L,P<0.01。且服用年限越长,Hcy浓度越低,r=-0.139,P<0.01。(4)服用多种维生素者动脉硬化性疾病的患病率低于未服用者,30.4%vs69.6%,P=0.051,差异接近显著。结论Hcy是动脉硬化性疾病和糖尿病的一种新的危险因素,其浓度随年龄、性别有所不同。

北京市居民营养补充剂使用现况

目的了解北京市各类人群营养补充剂的使用现况及相关因素。方法采用多阶段整群抽样法,共抽取北京市6区县4561人,问卷调查其营养补充剂的使用情况及相关情况。结果北京市居民营养补充剂的使用率为11.9%(标化率为10.1%),男性为9.0%(标化率为7.7%),女性为14.5%(标化率为12.4%)。使用率最高是维生素-矿物质复合补充剂。不同年龄、经济水平、文化水平、健康状况以及健康相关行为不同的人群,营养补充剂的使用率不同。结论北京市居民营养补充剂使用率远低于发达国家的水平。