Viruses and autism: A Bi-mutual cause and effect

Autism spectrum disorder(ASD)is a group of heterogeneous,multi-factorial,neurodevelopmental disorders resulting from genetic and environmental factors interplay.Infection is a significant trigger of autism,especially during the critical developmental period.There is a strong interplay between the viral infection as a trigger and a result of ASD.We aim to highlight the mutual relationship between autism and viruses.We performed a thorough literature review and included 158 research in this review.Most of the literature agreed on the possible effects of the viral infection during the critical period of development on the risk of developing autism,especially for specific viral infections such as Rubella,Cytomegalovirus,Herpes Simplex virus,Varicella Zoster Virus,Influenza virus,Zika virus,and severe acute respiratory syndrome coronavirus 2.Viral infection directly infects the brain,triggers immune activation,induces epigenetic changes,and raises the risks of having a child with autism.At the same time,there is some evidence of increased risk of infection,including viral infections in children with autism,due to lots of factors.There is an increased risk of developing autism with a specific viral infection during the early developmental period and an increased risk of viral infections in children with autism.In addition,children with autism are at increased risk of infection,including viruses.Every effort should be made to prevent maternal and early-life infections and reduce the risk of autism.Immune modulation of children with autism should be considered to reduce the risk of infection.

Do European Blocking Events Precede North Atlantic Oscillation Events?

Using a two-dimensional blocking index, the cause and effect relationship between European blocking （EB） events and North Atlantic Oscillation （NAO） events is investigated. It is shown that the EB event frequency is enhanced over Northern （Southern） Europe for negative （positive） phases of the NAO. Enhanced EB events over Northern Europe precede the establishment of negative phase NAO （NAO-） events, while the enhanced frequency of EB events over Southern Europe lags positive phase NAO （NAO＋） events. The physical explanation for why enhanced EB events over Northern （Southern） Europe lead （lag） NAO （NAO＋） events is also provided. It is found that the lead-lag relationship between EB events in different regions and the phase of NAO events can be explained in terms of the different latitudinal distribution of zonal wind associated with the different phases of NAO events. For NAO＋ events, the self-maintained eastward displacement of intensified midlatitude positive height anomalies owing to the intensified zonal wind can enhance the frequency of EB events over Southern Europe, thus supporting a standpoint that EB events over Southern Europe lag NAO＋ events. Over Northern Europe, EB events lead NAO- events because NAO- events arise from the self-maintained westward migration of intensified blocking anticyclones due to the weakened zonal wind in higher latitudes.

Impact of great gerbils(Rhombomys opimus) on desert plant communities

Great gerbil（Rhombomys opimus） colonies, with bare soil and herbaceous plants, are conspicuous to the background environment throughout their range area. In order to quantify the engineer role of great gerbils, we investigated the plant communities of 20 active colonies in the Junggar Basin, Xinjiang, China. In areas without disturbance, desert plant communities were dominated by the shrubs with low level species richness. In burrow areas and surrounding intermediate areas, which were disturbed by great gerbils, the shrubs were suppressed with the decrease of vegetation cover and aboveground biomass. As a result, ＂niche gaps＂ were created in disturbed areas and worked as a refuge for herbaceous annuals and perennials. So the existence of great gerbils increased the overall species richness of the desert. Furthermore, herbaceous annuals and perennials are the major food source for great gerbils in spring, indicating that great gerbils have a mutually beneficial relationship with herbaceous plants.