Septoplasty is widely used in the treatment of structural nasal obstructions,and it also has a good effect and a high degree of postoperative satisfaction.However,there a large number of structures demonstrate abnorma...Septoplasty is widely used in the treatment of structural nasal obstructions,and it also has a good effect and a high degree of postoperative satisfaction.However,there a large number of structures demonstrate abnormalities related to structural nasal obstruction,including the external nose,maxilla,nasal cavity and paranasal sinus.Nasal septum deviation is only one signs of structural nasal obstruction and does not represent all possible structural abnormalities of the nasal cavity and its surrounding structure.Septoplasty is only performed to correct deviations of the nasal septum,which in many cases is obviously insufficient in restoring the symmetry of the nasal structure.Therefore,septoplasty alone is not suitable for the treatment of most structural nasal obstructions.Nasal ventilation expansion surgery,which typically covers more abnormal structural correction procedures than septoplasty,should be used when describing the treatment of structural nasal obstruction.展开更多
To study the influence of intranasal medication on the structure, pathology and reversibility of the nasal mucosa to provide a basis for the feasibility of intr anasal route of drug administration Methods Nasal dr...To study the influence of intranasal medication on the structure, pathology and reversibility of the nasal mucosa to provide a basis for the feasibility of intr anasal route of drug administration Methods Nasal drops of gentamicin were placed in the nasal cavity of rabbits for 3, 5, 7 , 14 and 28 days After that, the drops were stopped and drugs protecting the nasomucosa were used for one and three weeks After being sacrificed over t ime, the nasomucosa of the rabbit was observed under optical and electron micros copes Results Damage to the nasal mucosa appeared to different extents with prolonged use of nasal drops Within 3-7 days of applying the drug, damages to the nasal mucosa gradually appeared, and after two and four weeks, were most serious After stop ping the drug, the nasal mucosa was gradually restored Conclusion Damages of drugs to the nasal mucosa could be restored The intranasal rou te of drug administration would be feasible and clinically applicable展开更多
基金The general work was supported by the Capital Medical University Student Research Innovation Project,China(No.XSKY2020158).
文摘Septoplasty is widely used in the treatment of structural nasal obstructions,and it also has a good effect and a high degree of postoperative satisfaction.However,there a large number of structures demonstrate abnormalities related to structural nasal obstruction,including the external nose,maxilla,nasal cavity and paranasal sinus.Nasal septum deviation is only one signs of structural nasal obstruction and does not represent all possible structural abnormalities of the nasal cavity and its surrounding structure.Septoplasty is only performed to correct deviations of the nasal septum,which in many cases is obviously insufficient in restoring the symmetry of the nasal structure.Therefore,septoplasty alone is not suitable for the treatment of most structural nasal obstructions.Nasal ventilation expansion surgery,which typically covers more abnormal structural correction procedures than septoplasty,should be used when describing the treatment of structural nasal obstruction.
文摘To study the influence of intranasal medication on the structure, pathology and reversibility of the nasal mucosa to provide a basis for the feasibility of intr anasal route of drug administration Methods Nasal drops of gentamicin were placed in the nasal cavity of rabbits for 3, 5, 7 , 14 and 28 days After that, the drops were stopped and drugs protecting the nasomucosa were used for one and three weeks After being sacrificed over t ime, the nasomucosa of the rabbit was observed under optical and electron micros copes Results Damage to the nasal mucosa appeared to different extents with prolonged use of nasal drops Within 3-7 days of applying the drug, damages to the nasal mucosa gradually appeared, and after two and four weeks, were most serious After stop ping the drug, the nasal mucosa was gradually restored Conclusion Damages of drugs to the nasal mucosa could be restored The intranasal rou te of drug administration would be feasible and clinically applicable
