Andrias davidianus,i.e.Chinese giant salamander(CGS),is one of the largest and oldest amphibians existing in the world and is also one of the valuable biological resources of China.Wild CGS has been threatened with ex...Andrias davidianus,i.e.Chinese giant salamander(CGS),is one of the largest and oldest amphibians existing in the world and is also one of the valuable biological resources of China.Wild CGS has been threatened with extinction in the past decades due to over capturing,deterioration of natural environment,the slow breeding and growth of the wild species in nature.However,in the past twenty years,with the breakthrough and progress of artificial breeding technology by artificial insemination,the number of artificially cultivated CGS has increased rapidly.Artificially cultivated CGS can either be released to the CGS living environment to increase the population in nature or legally applied in food and medicinal industry as a feedstock due to the unique nutritional and medicinal values of CGS as recorded historically.In this review,the nutritional components,bioactive components and medicinal activities of the artificially cultivated CGS will be summarized.The mucus,skin,meat and bone of CGS contain many different bioactive substances thereby having various medicinal activities including anti-aging,anti-fatigue,anti-tumor,therapy of burn and anti-infection and other physiological functions.This paper will further discuss the potential applications of the artificially cultivated CGS in healthcare industry and prospects of future technological development.展开更多
This paper discussed how to protect and control the quality of wild Chinese herbal medicine resources in nature reserves by taking Longyuwan National Forest Park within Funiu Mountain Nature Reserve as an example. Thr...This paper discussed how to protect and control the quality of wild Chinese herbal medicine resources in nature reserves by taking Longyuwan National Forest Park within Funiu Mountain Nature Reserve as an example. Through the combination of three methods including literature review, visiting and investigational studies, and field surveys, the data of investigation, collection and collation were analyzed. According to data of surveys, collection and collation, problems related to the protection of wild Chinese herbal medicine resources faced by Longyuwan Scenic Spot within Funiu Mountain Nature Reserve were also analyzed and protection strategies and quality control of wild Chinese herbal medicine resources in this nature reserve were discussed. It was expected that the results would provide important scientific references for the sustainable development, protection and quality control of wild Chinese herbal medicine resources within nature reserves.展开更多
目的总结天然产物抗肺癌的机制,为候选治疗肺癌新的前瞻性药物提供理论基础。方法利用肺癌、中药、药理学及其组合等关键词,收集中国知网、万方、维普、PubMed、Science Direct和Web of science等数据库有关天然产物抗肺癌作用研究的文...目的总结天然产物抗肺癌的机制,为候选治疗肺癌新的前瞻性药物提供理论基础。方法利用肺癌、中药、药理学及其组合等关键词,收集中国知网、万方、维普、PubMed、Science Direct和Web of science等数据库有关天然产物抗肺癌作用研究的文章,并进行总结。结果中医药治疗肺癌优势明显,具有药理机制新颖、毒性低、不良反应小的特点,可增效减毒、提高患者生活质量。天然产物主要包括黄酮类、生物碱类、多糖类、萜类、皂苷类和酚类,具有抑制肿瘤细胞周期、抑制增殖、诱导凋亡、促进自噬、抑制肿瘤细胞侵袭和转移的作用;天然产物与细胞毒性药物联合使用,可以增强疗效或降低耐药性,延缓肺癌的进展,延长患者的生存时间。结论中药含有多种黄酮、生物碱、萜及其苷类、多酚和其他可有效对抗肺癌的活性化合物,适合作为治疗肺癌的候选药物。展开更多
基金The authors would like to thank the National Key R&D Plan of China for providing support(NO:2016YFD0400203-4).
文摘Andrias davidianus,i.e.Chinese giant salamander(CGS),is one of the largest and oldest amphibians existing in the world and is also one of the valuable biological resources of China.Wild CGS has been threatened with extinction in the past decades due to over capturing,deterioration of natural environment,the slow breeding and growth of the wild species in nature.However,in the past twenty years,with the breakthrough and progress of artificial breeding technology by artificial insemination,the number of artificially cultivated CGS has increased rapidly.Artificially cultivated CGS can either be released to the CGS living environment to increase the population in nature or legally applied in food and medicinal industry as a feedstock due to the unique nutritional and medicinal values of CGS as recorded historically.In this review,the nutritional components,bioactive components and medicinal activities of the artificially cultivated CGS will be summarized.The mucus,skin,meat and bone of CGS contain many different bioactive substances thereby having various medicinal activities including anti-aging,anti-fatigue,anti-tumor,therapy of burn and anti-infection and other physiological functions.This paper will further discuss the potential applications of the artificially cultivated CGS in healthcare industry and prospects of future technological development.
基金Supported by Funding from the State Nationalities Affairs Commission(2015-GM-178)National Training Programs of Innovation and Entrepreneurship for Undergraduates(GCYS2016110001)
文摘This paper discussed how to protect and control the quality of wild Chinese herbal medicine resources in nature reserves by taking Longyuwan National Forest Park within Funiu Mountain Nature Reserve as an example. Through the combination of three methods including literature review, visiting and investigational studies, and field surveys, the data of investigation, collection and collation were analyzed. According to data of surveys, collection and collation, problems related to the protection of wild Chinese herbal medicine resources faced by Longyuwan Scenic Spot within Funiu Mountain Nature Reserve were also analyzed and protection strategies and quality control of wild Chinese herbal medicine resources in this nature reserve were discussed. It was expected that the results would provide important scientific references for the sustainable development, protection and quality control of wild Chinese herbal medicine resources within nature reserves.
文摘目的总结天然产物抗肺癌的机制,为候选治疗肺癌新的前瞻性药物提供理论基础。方法利用肺癌、中药、药理学及其组合等关键词,收集中国知网、万方、维普、PubMed、Science Direct和Web of science等数据库有关天然产物抗肺癌作用研究的文章,并进行总结。结果中医药治疗肺癌优势明显,具有药理机制新颖、毒性低、不良反应小的特点,可增效减毒、提高患者生活质量。天然产物主要包括黄酮类、生物碱类、多糖类、萜类、皂苷类和酚类,具有抑制肿瘤细胞周期、抑制增殖、诱导凋亡、促进自噬、抑制肿瘤细胞侵袭和转移的作用;天然产物与细胞毒性药物联合使用,可以增强疗效或降低耐药性,延缓肺癌的进展,延长患者的生存时间。结论中药含有多种黄酮、生物碱、萜及其苷类、多酚和其他可有效对抗肺癌的活性化合物,适合作为治疗肺癌的候选药物。
文摘目的:研究黄柏炮制前后17种氨基酸的含量变化情况进而评价黄柏炮制前后的寒热药性的变化。方法:采用反相高效液相色潽法,以异硫氰酸苯酯(PITC)为衍生化试剂衍生后进行HPLC分析。采用C18(250mm×4.6 mm,5μm)色谱柱,柱温为43℃;流动相A为0.1 mol·L-1醋酸钠缓冲液(以醋酸调p H 6.5)-乙腈(93∶7),流动相B为乙腈-水(4∶1),梯度洗脱,流速为1.0 m L·min-1;检测波长为254 nm。结果:17种氨基酸浓度在线性范围内呈良好的线性关系(r=0.996 8~0.999 5);回收率在96.7%~104.26%之间,RSD均小于3.0%。结论:本方法灵敏、准确,具有良好的重复性和稳定性,可用于黄柏中氨基酸的检测。
