In order to generate high quality ion beams through the stable radiation pressure acceleration（RPA） of the near critical density（NCD） target, we propose a new type of target where an ultra-thin high density（HD） ...In order to generate high quality ion beams through the stable radiation pressure acceleration（RPA） of the near critical density（NCD） target, we propose a new type of target where an ultra-thin high density（HD） layer is attached to the front surface of an NCD target, which has a preferable self-supporting property in the RPA experiments than the ultra-thin foil target. It is found that in one-dimensional particle-in-cell（PIC） simulation, by the block of the HD layer in the new target,there emerges the hole-boring process rather than propagation in the NCD layer when the intense laser pulse impinges on this target. As a result, a typical RPA structure that the compressed electron layer overlaps the ion layer as a whole is formed and a high quality ion beam is obtained, e.g., a circularly polarized laser pulse with normalized amplitude a0= 120 impinges on this new target and a 1.2 GeV monoenergetic ion beam is generated through the RPA of the NCD layer. Similar results are also found in the two-dimensional PIC simulation.展开更多
For composite electromagnetic(EM)scattering from rough surface and target above it in near-field condition,modified shooting and bouncing ray(SBR)method and integral equation method(IEM),which are analytic methods com...For composite electromagnetic(EM)scattering from rough surface and target above it in near-field condition,modified shooting and bouncing ray(SBR)method and integral equation method(IEM),which are analytic methods combined with two-scale model for rough surface,are proposed to solve the composite near-field scattering problems.And the modified method is verified in effectiveness and accuracy by comparing the simulation results with measured results.Finally,the composite near-fielding scattering characteristics of a slanted plane and rough water surface below are obtained by using the proposed methods,and the dynamic tendency of composite scattering characteristics versus near-fielding distance is analyzed,which may have practical contribution to engineering programs in need of radar targets near-field characteristics under extra-low-altitude conditions.展开更多
In this paper, near-infrared emitting long-persistence luminescent Zn3Ga2Ge2O10:Cr3?(ZGG) nanoparticles with diameters of 30–100 nm and bright luminescence were prepared by a sol–gel synthesis method. After the surf...In this paper, near-infrared emitting long-persistence luminescent Zn3Ga2Ge2O10:Cr3?(ZGG) nanoparticles with diameters of 30–100 nm and bright luminescence were prepared by a sol–gel synthesis method. After the surface amination, the nanoparticles were further bioconjugated with breast cancer-specific monoclonal antibody(anti-Ep CAM) to form ZGG-Ep CAM nanoprobes which can specifically target breast cancer cell lines(MCF7) in vitro. The results of in vitro images show that the luminescence signals from the cells treated with ZGG-Ep CAM nanoprobes are stronger than those from cells treated with ZGG-unconjugated antibody, indicating that the prepared ZGG-Ep CAM nanoprobes possessed excellent specific recognition capability. Furthermore, due to their long afterglow properties, the imaging could persist more than 1 h. Therefore, these nanoprobes could not only provide a high specificity detection method for cancer cells but also realize the long-time monitoring. Developed near-infrared emitting long-persistence luminescent nanoprobes will be expected to find new perspectives for cell therapy research and diagnosis applications.展开更多
The high frequency hybrid technique based on an iterative Physical Optics(PC)) and the method of equivalent current (MEC) approach is developed for predicting rangeresolution of the Radar Cross Section (RCS) in the sp...The high frequency hybrid technique based on an iterative Physical Optics(PC)) and the method of equivalent current (MEC) approach is developed for predicting rangeresolution of the Radar Cross Section (RCS) in the spatial domain. We introduce the hybrid highfrequency method to simulate range resolution of the extremely large target in the near zone. Thispaper applies this method to simulate the range resolution of the two 1 m X 1 m plates and the ship.The study improves the speed of simulatingthe range resolution of the extremely large target and isprepared for the application of the extrapolation and interpolation in the spatial domain.展开更多
Molecular imaging has emerged as a new discipline in gastrointestinal endoscopy.This technology encompasses modalities that can visualize disease-specific morphological or functional tissue changes based on the molecu...Molecular imaging has emerged as a new discipline in gastrointestinal endoscopy.This technology encompasses modalities that can visualize disease-specific morphological or functional tissue changes based on the molecular signature of individual cells.Molecular imaging has several advantages including minimal damage to tissues,repetitive visualization,and utility for conducting quantitative analyses.Advancements in basic science coupled with endoscopy have made early detection of gastrointestinal cancer possible.Molecular imaging during gastrointestinal endoscopy requires thedevelopment of safe biomarkers and exogenous probes to detect molecular changes in cells with high specificity anda high signal-to-background ratio.Additionally,a high-resolution endoscope with an accurate wide-field viewing capability must be developed.Targeted endoscopic imaging is expected to improve early diagnosis and individual therapy of gastrointestinal cancer.展开更多
基金supported by the National Natural Science Foundation of China(Grant Nos.11365020,11475026,11565022,and 11547304)the Science and Technology Program of Gansu Province of China(Grant No.1606RJZA090)+2 种基金the Fundamental Research Funds for the Higher Education Institutions of Gansu Province of China(2012)the Foundation of Northwest Normal University(Grant Nos.NWNU-LKQN-14-9 and NWNU-LKQN-16-3)partially supported by the Fundamental Research Funds for the Central Universities of China
文摘In order to generate high quality ion beams through the stable radiation pressure acceleration（RPA） of the near critical density（NCD） target, we propose a new type of target where an ultra-thin high density（HD） layer is attached to the front surface of an NCD target, which has a preferable self-supporting property in the RPA experiments than the ultra-thin foil target. It is found that in one-dimensional particle-in-cell（PIC） simulation, by the block of the HD layer in the new target,there emerges the hole-boring process rather than propagation in the NCD layer when the intense laser pulse impinges on this target. As a result, a typical RPA structure that the compressed electron layer overlaps the ion layer as a whole is formed and a high quality ion beam is obtained, e.g., a circularly polarized laser pulse with normalized amplitude a0= 120 impinges on this new target and a 1.2 GeV monoenergetic ion beam is generated through the RPA of the NCD layer. Similar results are also found in the two-dimensional PIC simulation.
基金Project supported by the National Natural Science Foundation of China(Grant No.61372033).
文摘For composite electromagnetic(EM)scattering from rough surface and target above it in near-field condition,modified shooting and bouncing ray(SBR)method and integral equation method(IEM),which are analytic methods combined with two-scale model for rough surface,are proposed to solve the composite near-field scattering problems.And the modified method is verified in effectiveness and accuracy by comparing the simulation results with measured results.Finally,the composite near-fielding scattering characteristics of a slanted plane and rough water surface below are obtained by using the proposed methods,and the dynamic tendency of composite scattering characteristics versus near-fielding distance is analyzed,which may have practical contribution to engineering programs in need of radar targets near-field characteristics under extra-low-altitude conditions.
基金supported by the Science and Technology Project in Xiamen(3502Z20132012)the Xiamen Southern Oceanographic Center(14GYY008NF08)+2 种基金the Natural Science Foundation of Fujian Province(2011J01220)the Major Program of Department of Science and Technology(2012Y4009)the Science and Technology Planning Project of Xiamen(3502Z20123036)
文摘In this paper, near-infrared emitting long-persistence luminescent Zn3Ga2Ge2O10:Cr3?(ZGG) nanoparticles with diameters of 30–100 nm and bright luminescence were prepared by a sol–gel synthesis method. After the surface amination, the nanoparticles were further bioconjugated with breast cancer-specific monoclonal antibody(anti-Ep CAM) to form ZGG-Ep CAM nanoprobes which can specifically target breast cancer cell lines(MCF7) in vitro. The results of in vitro images show that the luminescence signals from the cells treated with ZGG-Ep CAM nanoprobes are stronger than those from cells treated with ZGG-unconjugated antibody, indicating that the prepared ZGG-Ep CAM nanoprobes possessed excellent specific recognition capability. Furthermore, due to their long afterglow properties, the imaging could persist more than 1 h. Therefore, these nanoprobes could not only provide a high specificity detection method for cancer cells but also realize the long-time monitoring. Developed near-infrared emitting long-persistence luminescent nanoprobes will be expected to find new perspectives for cell therapy research and diagnosis applications.
基金Supported by the National Natural Science Foundation of China(60301007)
文摘The high frequency hybrid technique based on an iterative Physical Optics(PC)) and the method of equivalent current (MEC) approach is developed for predicting rangeresolution of the Radar Cross Section (RCS) in the spatial domain. We introduce the hybrid highfrequency method to simulate range resolution of the extremely large target in the near zone. Thispaper applies this method to simulate the range resolution of the two 1 m X 1 m plates and the ship.The study improves the speed of simulatingthe range resolution of the extremely large target and isprepared for the application of the extrapolation and interpolation in the spatial domain.
基金Supported by The National Research Foundation of Korea grant funded by the Korea government No. 2010-0023295the Songeui Scholar Research grant funded by the Catholic University of Korea
文摘Molecular imaging has emerged as a new discipline in gastrointestinal endoscopy.This technology encompasses modalities that can visualize disease-specific morphological or functional tissue changes based on the molecular signature of individual cells.Molecular imaging has several advantages including minimal damage to tissues,repetitive visualization,and utility for conducting quantitative analyses.Advancements in basic science coupled with endoscopy have made early detection of gastrointestinal cancer possible.Molecular imaging during gastrointestinal endoscopy requires thedevelopment of safe biomarkers and exogenous probes to detect molecular changes in cells with high specificity anda high signal-to-background ratio.Additionally,a high-resolution endoscope with an accurate wide-field viewing capability must be developed.Targeted endoscopic imaging is expected to improve early diagnosis and individual therapy of gastrointestinal cancer.
