Background:Cancer of Head and Neck(HNC)is the 2 nd common cancer in India leading to around 8%of the global cancer mortality.Intensity-modulated radiation therapy(IMRT)is advanced method minimizing exposure of radiati...Background:Cancer of Head and Neck(HNC)is the 2 nd common cancer in India leading to around 8%of the global cancer mortality.Intensity-modulated radiation therapy(IMRT)is advanced method minimizing exposure of radiation to adjacent normal structures but is associated with higher fatigue indirectly elevating distress levels.Medical Qigong(MQ),a meditative mind therapy has numerous health benefits.The purpose of the current study was to investigate effect of MQ therapy on distress,fatigue,and quality of life in HNC patients undergoing IMRT.Materials and Methods:This experimental study was conducted on 16 Hospitalized HNC subjects undergoing IMRT aged 18–65 years.All the subjects performed Qigong Walk Cycle for 5 weekdays for 4 weeks from initiation of IMRT.Scores of Brief Fatigue Inventory(BFI),6 min walk distance(6 MWD),Functional Assessment of Cancer Therapy-Head and Neck(FACT-HN)were documented at the baseline and at end of 4 th week and compared.Results:IBM SPSS Statistics version 23.0;Indian version of Windows was used for statistical analysis.The 16 HNC subjects majorly rural residents(62.5%)of mean age group 47.68±10.25 years with tobacco chewing as prevalent habit(94%)with maximum cases recorded in stage III of the disease.The pre and post test score comparison of serum cortisol,BFI and 6 MWD found high statistical significance with P=0.001 while that of the total and all components of FACT HN was found to be significant with P≤0.05.Conclusion:MQ therapy was effective in managing the levels of distress and fatigue thereby improving quality of life of all HNC subjects.展开更多
Patients with locally advanced oropharyngeal cancer are at risk for poor outcomes due to the multi-modal nature of treatment and the potential for treatmentrelated toxicity.Although treatment with concurrent chemother...Patients with locally advanced oropharyngeal cancer are at risk for poor outcomes due to the multi-modal nature of treatment and the potential for treatmentrelated toxicity.Although treatment with concurrent chemotherapy and radiotherapy has drastically reduced the need for a debilitating and disfiguring surgery,treatment related toxicities are often difficult to control.Acute toxicities include mucositis,skin desquamation,depression,cachexia,fatigue and nausea and vomiting.Failure to control these symptoms can adversely affect the patient's ability to complete their treatment regimen.Although there are many promising new treatments in the area of symptom management for this patient population,a review of the literature reflects the need for more research.展开更多
文摘Background:Cancer of Head and Neck(HNC)is the 2 nd common cancer in India leading to around 8%of the global cancer mortality.Intensity-modulated radiation therapy(IMRT)is advanced method minimizing exposure of radiation to adjacent normal structures but is associated with higher fatigue indirectly elevating distress levels.Medical Qigong(MQ),a meditative mind therapy has numerous health benefits.The purpose of the current study was to investigate effect of MQ therapy on distress,fatigue,and quality of life in HNC patients undergoing IMRT.Materials and Methods:This experimental study was conducted on 16 Hospitalized HNC subjects undergoing IMRT aged 18–65 years.All the subjects performed Qigong Walk Cycle for 5 weekdays for 4 weeks from initiation of IMRT.Scores of Brief Fatigue Inventory(BFI),6 min walk distance(6 MWD),Functional Assessment of Cancer Therapy-Head and Neck(FACT-HN)were documented at the baseline and at end of 4 th week and compared.Results:IBM SPSS Statistics version 23.0;Indian version of Windows was used for statistical analysis.The 16 HNC subjects majorly rural residents(62.5%)of mean age group 47.68±10.25 years with tobacco chewing as prevalent habit(94%)with maximum cases recorded in stage III of the disease.The pre and post test score comparison of serum cortisol,BFI and 6 MWD found high statistical significance with P=0.001 while that of the total and all components of FACT HN was found to be significant with P≤0.05.Conclusion:MQ therapy was effective in managing the levels of distress and fatigue thereby improving quality of life of all HNC subjects.
文摘目的 为降低长时间颈部后仰对航空机务人员身心健康造成影响,探讨航空机务人员在托举作业过程中长时间保持颈部后仰姿势对颈部肌肉表面肌电的影响。方法 择12名在校大学生作为研究对象,受试者站立在飞机机翼下方保持颈部后仰固定姿势模拟机务人员进行托举作业,记录受试者主观疲劳感觉评分(rating of perceived exertion,RPE),同时采集斜方肌、胸锁乳头肌和颈部夹肌的表面肌电信号,分析并计算肌电信号均方根(root mean square,RMS)、积分肌电(integral electromyography,iEMG)、中值频率(median frequency,MF)和平均功率频率(mean power frequency,MPF),并结合主观疲劳感觉评分进行相关性和回归分析。结果 胸锁乳突肌、斜方肌和颈部夹肌的iEMG和RMS变化与托举时间呈正相关关系,其中颈部夹肌的iEMG和胸锁乳突肌RMS相关程度最高,其相关系数分别为0.48和0.84,拟合程度分别为0.69和0.71,差异具有统计学意义(P<0.05);胸锁乳突肌、斜方肌和颈部夹肌的MPF和MF变化与时间呈负相关关系,其中颈部夹肌的MPF和MF相关程度最高,其相关系数分别为0.95和0.96,拟合程度分别为-0.97和-0.98,差异具有统计学意义(P<0.05);胸锁乳突肌、斜方肌和颈部夹肌的时域特征与RPE相关性无统计学意义(P>0.05),但频域特征与RPE相关性有统计学意义(P<0.05),相关性MPF指标优于MF。结论 长时间颈部后仰作业会引发斜方肌、胸锁乳头肌和颈部夹肌疲劳,颈部夹肌先于斜方肌和胸锁乳突肌发生疲劳,同时肌电信号的频域指标可作为一个较好的评价指标用于颈部肌肉疲劳评价。
文摘Patients with locally advanced oropharyngeal cancer are at risk for poor outcomes due to the multi-modal nature of treatment and the potential for treatmentrelated toxicity.Although treatment with concurrent chemotherapy and radiotherapy has drastically reduced the need for a debilitating and disfiguring surgery,treatment related toxicities are often difficult to control.Acute toxicities include mucositis,skin desquamation,depression,cachexia,fatigue and nausea and vomiting.Failure to control these symptoms can adversely affect the patient's ability to complete their treatment regimen.Although there are many promising new treatments in the area of symptom management for this patient population,a review of the literature reflects the need for more research.
