Resonators in circuit quantum electrodynamics systems naturally carry multiple modes, which may have non-negligible influence on qubit parameters and device performance. While new theories and techniques are under inv...Resonators in circuit quantum electrodynamics systems naturally carry multiple modes, which may have non-negligible influence on qubit parameters and device performance. While new theories and techniques are under investigation to deal with the multi-mode effects in circuit quantum electrodynamics systems, researchers have proposed novel engineering designs featuring multi-mode resonators to achieve enhanced functionalities of superconducting quantum processors. Here, we propose multi-mode bus coupling architecture, in which superconducting qubits are coupled to multiple bus resonators to gain larger coupling strength. Applications of multi-mode bus couplers can be helpful for improving i SWAP gate fidelity and gate speed beyond the limit of single-mode scenario. The proposed multi-mode bus coupling architecture is compatible with a scalable variation of the traditional bus coupling architecture. It opens up new possibilities for realization of scalable superconducting quantum computation with circuit quantum electrodynamics systems.展开更多
BACKGROUND It has been said that the number of orthopaedic claims has increased in the last few years. Investigation through the most prevalent cause would help to prevent further cases.AIM To review the cases of medi...BACKGROUND It has been said that the number of orthopaedic claims has increased in the last few years. Investigation through the most prevalent cause would help to prevent further cases.AIM To review the cases of medical complaints in orthopedic patients who had been involved in a traumatic accident.METHODS A retrospective multi-center review of trauma orthopaedic-related malpractice lawsuits from 2010 to 2021 was conducted utilizing the regional medicolegal database. Defendant and plaintiff characteristics along with fracture location, allegations, and litigation outcomes were investigated.RESULTS A total of 228 claims referred to trauma-related conditions with a mean age of 31.29 ± 12.56 were enrolled. The most common injuries were at hand, thigh, elbow, and forearm, respectively.Likewise, the most common alleged complication was related to malunion or nonunion. In 47% of the cases, the main problem that led to the complaint was the inappropriate or insufficient explanation to the patient, and in 53%, there was a problem in the surgery. Eventually, 76% of the complaints resulted in a defense verdict, and 24% resulted in a plaintiff verdict.CONCLUSION Surgical treatment of hand injuries and surgery in non-educational hospitals received the most complaints. The majority of litigation outcomes were caused by a physician’s failure to fully explain and educate the traumatic orthopedic patients and technological errors.展开更多
Diagnostic errors are important in all branches of medicine because they are an indication of poor patient care. Since the early 1970s,physicians have been subjected to an increasing number of medical malpractice clai...Diagnostic errors are important in all branches of medicine because they are an indication of poor patient care. Since the early 1970s,physicians have been subjected to an increasing number of medical malpractice claims. Radiology is one of the specialties most liable to claims of medical negligence.Most often,a plaintiff's complaint against a radiologist will focus on a failure to diagnose. The etiology of radiological error is multi-factorial.Errors fall into recurrent patterns.Errors arise from poor technique,failures of perception,lack of knowledge and misjudgments.The work of diagnostic radiology consists of the complete detection of all abnormalities in an imaging examination and their accurate diagnosis. Every radiologist should understand the sources of error in diagnostic radiology as well as the elements of negligence that form the basis of malpractice litigation.Error traps need to be uncovered and highlighted,in order to prevent repetition of the same mistakes.This article focuses on the spectrum of diagnostic errors in radiology, including a classification of the errors,and stresses the malpractice issues in mammography,chest radiology and obstetric sonography.Missed fractures in emergency and communication issues between radiologists and physicians are also discussed.展开更多
Electrostatic pseudo liquid membrane(ESPLIM)separation process,developed recently in this laboratory,is a novel chemical separation technology.ESPLIM is an interdisciplinary technology evolved from thecombination of...Electrostatic pseudo liquid membrane(ESPLIM)separation process,developed recently in this laboratory,is a novel chemical separation technology.ESPLIM is an interdisciplinary technology evolved from thecombination of solvent extraction,liquid membrane and electrostatic techniques.It can be used to separate,purify and concentrate specific solutes from aqueous solutions.Therefore,it is suitable for the recovery ofvaluable metals from aqueous solutions in the field of hydrometallurgy(including nuclear fuel cycles)and forthe processes of waste water treatment.This paper discusses the basic principles of this new technology.Taking the extraction of Co<sup>2+</sup>by D2EHPA as an example,effects on metal extraction of electrical fieldstrength,extractant concentration and the flow ratio of feed to stripping solution have been studied.Exper-iments show that the once through extraction efficiency of Co<sup>2+</sup>can reach 99% while Co<sup>2+</sup>can be concen-trated up to 40—50g/L in the stripping solution.展开更多
Large active wing deformation is a significant way to generate high aerodynamic forces required in bat's flapping flight. Besides the twisting, elementary morphing models of a bat wing are proposed, including wing-be...Large active wing deformation is a significant way to generate high aerodynamic forces required in bat's flapping flight. Besides the twisting, elementary morphing models of a bat wing are proposed, including wing-bending in the spanwise direction,wing-cambering in the chordwise direction, and wing area-changing. A plate of aspect ratio 3 is used to model a bat wing, and a three-dimensional unsteady panel method is used to predict the aerodynamic forces. It is found that the cambering model has great positive influence on the lift, followed by the area-changing model and then the bending model. Further study indicates that the vortex control is a main mechanism to produce high aerodynamic forces. The mechanisms of aerodynamic force enhancement are asymmetry of the cambered wing and amplification effects of wing area-changing and wing bending. Lift and thrust are generated mainly during downstroke, and they are almost negligible during upstroke by the integrated morphing model-wing.展开更多
Transcriptomic changes at the cessation of sugar accumulation in the pericarp of Vitis vinifera were addressed on single berries re-synchronised according to their individual growth patterns.The net rates of water,sug...Transcriptomic changes at the cessation of sugar accumulation in the pericarp of Vitis vinifera were addressed on single berries re-synchronised according to their individual growth patterns.The net rates of water,sugars and K+accumulation inferred from individual growth and solute concentration confirmed that these inflows stopped simultaneously in the ripe berry,while the small amount of malic acid remaining at this stage was still being oxidised at low rate.Re-synchronised individual berries displayed negligible variations in gene expression among triplicates.RNA-seq studies revealed sharp reprogramming of cell-wall enzymes and structural proteins at the stop of phloem unloading,associated with an 80%repression of multiple sugar transporters and aquaporins on the plasma or tonoplast membranes,with the noticeable exception of H^(+)/sugar symporters,which were rather weakly and constitutively expressed.This was verified in three genotypes placed in contrasted thermo-hydric conditions.The prevalence of SWEET suggests that electrogenic transporters would play a minor role on the plasma membranes of SE/CC complex and the one of the flesh,while sucrose/H+exchangers dominate on its tonoplast.Cis-regulatory elements present in their promoters allowed to sort these transporters in different groups,also including specific TIPs and PIPs paralogs,and cohorts of cell wall-related genes.Together with simple thermodynamic considerations,these results lead to propose that H^(+)/sugar exchangers at the tonoplast,associated with a considerably acidic vacuolar pH,may exhaust cytosolic sugars in the flesh and alleviate the need for supplementary energisation of sugar transport at the plasma membrane.展开更多
Correlated ion stopping arising from an intense cluster ion beam(CIB)interacting with an ultradense plasma target of relevance to inertial confinement fusion(ICF)is first investigated in a two-body approximation in an...Correlated ion stopping arising from an intense cluster ion beam(CIB)interacting with an ultradense plasma target of relevance to inertial confinement fusion(ICF)is first investigated in a two-body approximation in an arbitrarily degenerate electron fluid target.The specific advantages of CIB-driven ICF are first demonstrated through 1D simulations,highlighting the very fine focusing of the ion beam on the target pellet.Then,theN-body configurations of ion debris resulting from the impact of heavy cluster ions are determined in terms of their specific topology.The validities of the usual assumptions of equal ion fragment charge and negligible coupling between stopping and Coulomb explosion are assessed.展开更多
BACKGROUND Acute hand and wrist injuries are common and may lead to long-term disability if not managed adequately.Claims for negligence have been increasing in medical practice over the past few decades,with hand and...BACKGROUND Acute hand and wrist injuries are common and may lead to long-term disability if not managed adequately.Claims for negligence have been increasing in medical practice over the past few decades,with hand and wrist injuries and their treatment representing a significant percentage of orthopedic surgery lawsuits.There is no available literature regarding medical malpractice claims in hand and wrist injuries and surgery in Greece.AIM To identify claims related to hand and wrist trauma and surgery and to define the reasons of successful litigations.METHODS We performed a retrospective study of all legal claims of negligence for hand and upper extremity surgery that went to a trial,attributed to all surgical specialties,in Greece for a 20-year period.Data was further analyzed to identify claims related to hand and wrist trauma and surgery.RESULTS There were six malpractice claims related to hand and wrist trauma that ended in a trial.A missed diagnosis,which resulted in failure of initial management of the injury,was the main reason for a claim.Three of the six cases resulted in complete or partial loss of a finger.Two cases are still open,requiring an expert witness’s report,two cases were closed in favor of the defendant,and two cases were closed in favor of the plaintiff with a mean compensation of€2000(€1000-€3000).CONCLUSION Missed diagnosis was the main reason for a malpractice claim.Better understanding of factors leading to successful claims will help surgeons improve their practice to minimize legal implications and litigation.展开更多
A multi-electrode array is commonly applied in a plasma sparker to generate stable acoustic pulses.In this paper, the effects of the electrode configuration on the performance of a plasma sparker have been investigate...A multi-electrode array is commonly applied in a plasma sparker to generate stable acoustic pulses.In this paper, the effects of the electrode configuration on the performance of a plasma sparker have been investigated. In terms of the load electrical characteristics, the electrode radius and distance have negligible influence on the electric characteristics, whereas a larger electrode number results in a smaller voltage and a larger current but has little effect on the load energy. Regarding the acoustic characteristics, both the expansion and collapse pulses can be increased by decreasing the electrode tip radius. the influence of the electrode number and electrode gap distance on the amplitude of the expansion pulse was found to be negligible. And the amplitude of the collapse pulse decreases significantly with increasing electrode number. Increasing the electrode number decreases the energy efficiency for intense bubble interactions, thus, a small electrode tip radius and a small electrode number are preferred for the design of a plasma sparker if the total discharge energy is given.展开更多
The flame temperature in the combustor of a gas turbine is usually as high as 2000 K, while the maximum temperature that can be endured by metal materials is less than 1200 K at present. Therefore, various protective ...The flame temperature in the combustor of a gas turbine is usually as high as 2000 K, while the maximum temperature that can be endured by metal materials is less than 1200 K at present. Therefore, various protective and cooling measures are needed to ensure the operation life of the liner wall which wraps the flame. The lean premixed combustor can meet the increasingly stringent emission requirements, but it requires more air for premixed combustion and then less air for cooling and dilution. In order to obtain a better impingement jet cooling structure, this paper studied the impingement jet cooling structure with vertical circular holes of equal diameter under single outlet condition. The structural variables studied include the jet hole diameter D, the impinging distance Z, the jet hole length(jet plate thickness) t, and the jet-to-jet spacing X is ignored. Among them, X/D(the ratio of the jet-to-jet spacing to the jet diameter) is inversely correlated with the mass flow rate. Within the constant X/D being equal to 10, the influence of D, Z and t on the average heat transfer coefficient h of the target surface under same mass flow was determined by means of conjugate numerical heat transfer analysis and orthogonal test. The results show that Z has significant influence on h, D has moderate influence on h, and t has negligible influence on h. Further, by means of regression orthogonal test, the influence trend of parameters Z and D on h at X/D=10 was studied. The optimal values of Z and D within the research scope were found.展开更多
The intrinsic and global kinetics of methanol synthesis from carbon monoxide, carbon dioxide and hydrogen in the presence of C301 commercial catalyst is studied. The investigation is performed under typical commercial...The intrinsic and global kinetics of methanol synthesis from carbon monoxide, carbon dioxide and hydrogen in the presence of C301 commercial catalyst is studied. The investigation is performed under typical commercial conditions in an isothermal plug-flow integral reactor and展开更多
Two heat transfer parameters in the fixed bed,radial effective conductiviw k<sub>er</sub>,and wall heat transfer coefficient h<sub>w</sub>are estimated by using the method of orthogonal colloca...Two heat transfer parameters in the fixed bed,radial effective conductiviw k<sub>er</sub>,and wall heat transfer coefficient h<sub>w</sub>are estimated by using the method of orthogonal collocation and non-linear least square.The temperatures at forty collo-cation points distributed along the radial direction are measured simultaneously by means of multiehannel data logger.Theeffects of bed height,Re<sub>p</sub>,d<sub>t</sub>/d<sub>p</sub>,gas inlet temperature and wall temperature on k<sub>er</sub>and h<sub>w</sub> are studied.The results indicatethat the effect of gas inlet temperature and wall temperature is negligible.Bed height will only influence the parameter es-timations in shallow bed and at low Re<sub>p</sub>.Both k<sub>er</sub>and h<sub>w</sub> tend to reach a limit with increasing bed height.The asymptoticbed height which is independent of d<sub>p</sub> is about 0.5 m,while the asymptotic values of k<sub>er</sub>and h<sub>w</sub> increase with d<sub>p</sub>.The pa-rameters obtained with the wall being heated are about 10% lower than those with the wall being cooled.k<sub>er</sub>,h<sub>w</sub> and stag-nant contribution terms k<sub>er</sub>and h<sub>w</sub> are all related to dp·k<sub>er</sub>and h<sub>w</sub> estimated at the asymptotic bed height are correlated bythe following equations:k<sub>er</sub>=0.199+0.015 d<sub>t</sub>/d<sub>p</sub>+0.0020/(1+14.15(d<sub>p</sub>/d<sub>t</sub>)<sup>2</sup>)Re<sub>p</sub>h<sub>w</sub>=33.4+4.23d<sub>t</sub>/d<sub>p</sub>+0.333/(1+8.54(d<sub>p</sub>/d<sub>t</sub>)<sup>2</sup>)Re<sub>p</sub>(5.5【d<sub>t</sub>/d<sub>p</sub>【13)(100【Re<sub>p</sub>【500)展开更多
It has been studied that the residence time distribution(RTD)function in a screw extruder in relation to that in thescrew and that in the die.For a complex flow field such as that between screw and die,it was supposed...It has been studied that the residence time distribution(RTD)function in a screw extruder in relation to that in thescrew and that in the die.For a complex flow field such as that between screw and die,it was supposed that the RTDfunction in the screw and that in the die were almost independent on each other.Therefore,a probabilistic method wasused to predict the RTD function in a complete extruder from that in the screw and that in the die.The experiments fordetermining the RTD were based on a stimulus-response technique.The results predicted,both in single-screw extruderand in twin-screw extruder,were in good agreement with those experimentally obtained.展开更多
Flipping of water dipoles in carbon nanotubes is of great importance in many physical and biological applications,such as signal amplification,molecular switches and nano-gates.Ahead of these applications,understandin...Flipping of water dipoles in carbon nanotubes is of great importance in many physical and biological applications,such as signal amplification,molecular switches and nano-gates.Ahead of these applications,understanding and inhibiting the non-negligible thermal noise is essential.Here,we use molecular dynamics simulations to show that the flipping frequency of water dipoles increases with the rising temperature,and the thermal noise can be suppressed by imposed charges and external uniform electric fields.Furthermore,the water dipoles flip periodically between two equiprobable and stable states under alternating electric fields.These two stable states may be adopted to store 0 and 1 bits for memory storage or molecular computing.展开更多
Correlation measurements of neutrons and fragments have been performed in a reaction of 33.4MeV/u ^(17)N on a ^(9)Be target.Energy spectra of n and nitrogen fragments were obtained at different angles.Based on the nuc...Correlation measurements of neutrons and fragments have been performed in a reaction of 33.4MeV/u ^(17)N on a ^(9)Be target.Energy spectra of n and nitrogen fragments were obtained at different angles.Based on the nuclear diffraction dissociation model,the measured energy spectra and the neutron angular distributions were reproduced quite well assuming that ^(17)N was composed of ^(16)N and n or ^(15)N and 2n interacting with the nonlocal separable potential.The satisfactory agreement between the theoretical calculations and the experimental data shows that the contribution of Coulomb dissociation is negligible in the reaction concerned.展开更多
We report a perpendicular magnetic tunnel junction(p MTJ)cell with a tunnel magnetoresistance(TMR)ratio of nearly 200%at room temperature based on Co Fe B/Ta/Co Fe B as the free layer(FL)and a synthetic antiferromagne...We report a perpendicular magnetic tunnel junction(p MTJ)cell with a tunnel magnetoresistance(TMR)ratio of nearly 200%at room temperature based on Co Fe B/Ta/Co Fe B as the free layer(FL)and a synthetic antiferromagnetic(SAF)multilayer[Pt/Co]/Ru/[Pt/Co]/Ta/Co Fe B as the reference layer(RL).The field-driven magnetization switching measurements show that the p MTJs exhibit an anomalous TMR hysteresis loop.The spin-polarized layer Co Fe B of SAF-RL has a lower critical switching field than that of FL.The reason is related to the interlayer exchange coupling(IEC)through a moderately thick Ta spacer layer among SAF-RLs,which generates a moderate and negative bias magnetic field on Co Fe B of RL.However,the IEC among RLs has a negligible influence on the current-driven magnetization switching of FL and its magnetization dynamics.展开更多
The fabrication of self-catalyzed InP nanowires(NWs)is investigated under different growth conditions.Indium droplets induced by surface reconstruction act as nucleation sites for NW growth.Vertical standing NWs with ...The fabrication of self-catalyzed InP nanowires(NWs)is investigated under different growth conditions.Indium droplets induced by surface reconstruction act as nucleation sites for NW growth.Vertical standing NWs with uniform cross sections are obtained under optimized conditions.It is confirmed that the growth rate of NWs is strongly affected by the surface diffusion adatoms while contributions from the direct impingement of vapor species onto the In droplets can be negligible.The results indicate that the droplet acts as an adatom collector rather than a catalyst.Moreover,the diffusion flow rate of adatoms increases with time at the beginning of growth and stabilizes as the growth proceeds.展开更多
The theory of the screening-photovoltaic solitons is improved in biased photorefractive-photovoltaic crystals.When the photovoltaic effect is negligible,the screening-photovoltaic solitons are the screening ones,and t...The theory of the screening-photovoltaic solitons is improved in biased photorefractive-photovoltaic crystals.When the photovoltaic effect is negligible,the screening-photovoltaic solitons are the screening ones,and their space-charge field is the space-charge field of the screening solitons.If the external field is absent,the screening-photovoltaic solitons are the photovoltaic ones on the open-and closed-circuit conditions,and their space-charge field is of the photovoltaic solitons.We also show theoretically that the screening and the photovoltaic solitons on the open-and closed-circuit conditions may be studies together as the screening-photovoltaic solitons.展开更多
Contrary to that without considering the hydrodynamic motion,the mass effect in the transverse momentum distribution of high energy nuclear collisions is/bund not negligible at high temperature after tie hydrodynamic ...Contrary to that without considering the hydrodynamic motion,the mass effect in the transverse momentum distribution of high energy nuclear collisions is/bund not negligible at high temperature after tie hydrodynamic motion is considered.So on the occasions for high temperature,such as the formation of quark-gluon-plasma,mass effect must be taken into account.展开更多
基金partially supported by the National Natural Science Foundation of China(Grant No.60836001)the Key R&D Program of Guangdong Province(Grant No.2019B010143002)。
文摘Resonators in circuit quantum electrodynamics systems naturally carry multiple modes, which may have non-negligible influence on qubit parameters and device performance. While new theories and techniques are under investigation to deal with the multi-mode effects in circuit quantum electrodynamics systems, researchers have proposed novel engineering designs featuring multi-mode resonators to achieve enhanced functionalities of superconducting quantum processors. Here, we propose multi-mode bus coupling architecture, in which superconducting qubits are coupled to multiple bus resonators to gain larger coupling strength. Applications of multi-mode bus couplers can be helpful for improving i SWAP gate fidelity and gate speed beyond the limit of single-mode scenario. The proposed multi-mode bus coupling architecture is compatible with a scalable variation of the traditional bus coupling architecture. It opens up new possibilities for realization of scalable superconducting quantum computation with circuit quantum electrodynamics systems.
基金the Clinical Research Development Center of Taleghani and Imam Ali Hospital, University of Medical Sciences, Kermanshah, IranShohada Tajrish Clinical Research Development Center at Shahid Beheshti University of Medical Sciences in Tehran, Iran, for their support。
文摘BACKGROUND It has been said that the number of orthopaedic claims has increased in the last few years. Investigation through the most prevalent cause would help to prevent further cases.AIM To review the cases of medical complaints in orthopedic patients who had been involved in a traumatic accident.METHODS A retrospective multi-center review of trauma orthopaedic-related malpractice lawsuits from 2010 to 2021 was conducted utilizing the regional medicolegal database. Defendant and plaintiff characteristics along with fracture location, allegations, and litigation outcomes were investigated.RESULTS A total of 228 claims referred to trauma-related conditions with a mean age of 31.29 ± 12.56 were enrolled. The most common injuries were at hand, thigh, elbow, and forearm, respectively.Likewise, the most common alleged complication was related to malunion or nonunion. In 47% of the cases, the main problem that led to the complaint was the inappropriate or insufficient explanation to the patient, and in 53%, there was a problem in the surgery. Eventually, 76% of the complaints resulted in a defense verdict, and 24% resulted in a plaintiff verdict.CONCLUSION Surgical treatment of hand injuries and surgery in non-educational hospitals received the most complaints. The majority of litigation outcomes were caused by a physician’s failure to fully explain and educate the traumatic orthopedic patients and technological errors.
文摘Diagnostic errors are important in all branches of medicine because they are an indication of poor patient care. Since the early 1970s,physicians have been subjected to an increasing number of medical malpractice claims. Radiology is one of the specialties most liable to claims of medical negligence.Most often,a plaintiff's complaint against a radiologist will focus on a failure to diagnose. The etiology of radiological error is multi-factorial.Errors fall into recurrent patterns.Errors arise from poor technique,failures of perception,lack of knowledge and misjudgments.The work of diagnostic radiology consists of the complete detection of all abnormalities in an imaging examination and their accurate diagnosis. Every radiologist should understand the sources of error in diagnostic radiology as well as the elements of negligence that form the basis of malpractice litigation.Error traps need to be uncovered and highlighted,in order to prevent repetition of the same mistakes.This article focuses on the spectrum of diagnostic errors in radiology, including a classification of the errors,and stresses the malpractice issues in mammography,chest radiology and obstetric sonography.Missed fractures in emergency and communication issues between radiologists and physicians are also discussed.
文摘Electrostatic pseudo liquid membrane(ESPLIM)separation process,developed recently in this laboratory,is a novel chemical separation technology.ESPLIM is an interdisciplinary technology evolved from thecombination of solvent extraction,liquid membrane and electrostatic techniques.It can be used to separate,purify and concentrate specific solutes from aqueous solutions.Therefore,it is suitable for the recovery ofvaluable metals from aqueous solutions in the field of hydrometallurgy(including nuclear fuel cycles)and forthe processes of waste water treatment.This paper discusses the basic principles of this new technology.Taking the extraction of Co<sup>2+</sup>by D2EHPA as an example,effects on metal extraction of electrical fieldstrength,extractant concentration and the flow ratio of feed to stripping solution have been studied.Exper-iments show that the once through extraction efficiency of Co<sup>2+</sup>can reach 99% while Co<sup>2+</sup>can be concen-trated up to 40—50g/L in the stripping solution.
基金Project supported by the National Natural Science Foundation of China(No.10602061)
文摘Large active wing deformation is a significant way to generate high aerodynamic forces required in bat's flapping flight. Besides the twisting, elementary morphing models of a bat wing are proposed, including wing-bending in the spanwise direction,wing-cambering in the chordwise direction, and wing area-changing. A plate of aspect ratio 3 is used to model a bat wing, and a three-dimensional unsteady panel method is used to predict the aerodynamic forces. It is found that the cambering model has great positive influence on the lift, followed by the area-changing model and then the bending model. Further study indicates that the vortex control is a main mechanism to produce high aerodynamic forces. The mechanisms of aerodynamic force enhancement are asymmetry of the cambered wing and amplification effects of wing area-changing and wing bending. Lift and thrust are generated mainly during downstroke, and they are almost negligible during upstroke by the integrated morphing model-wing.
基金We would like to thank the Poupelain Foundation,the Comite Interprofessionnel des Vins de Bordeaux(CIVB)the Agence Nationale de la Recherche(G2WAS project,ANR-19-CE20-0024)for providing the financial support of this study.
文摘Transcriptomic changes at the cessation of sugar accumulation in the pericarp of Vitis vinifera were addressed on single berries re-synchronised according to their individual growth patterns.The net rates of water,sugars and K+accumulation inferred from individual growth and solute concentration confirmed that these inflows stopped simultaneously in the ripe berry,while the small amount of malic acid remaining at this stage was still being oxidised at low rate.Re-synchronised individual berries displayed negligible variations in gene expression among triplicates.RNA-seq studies revealed sharp reprogramming of cell-wall enzymes and structural proteins at the stop of phloem unloading,associated with an 80%repression of multiple sugar transporters and aquaporins on the plasma or tonoplast membranes,with the noticeable exception of H^(+)/sugar symporters,which were rather weakly and constitutively expressed.This was verified in three genotypes placed in contrasted thermo-hydric conditions.The prevalence of SWEET suggests that electrogenic transporters would play a minor role on the plasma membranes of SE/CC complex and the one of the flesh,while sucrose/H+exchangers dominate on its tonoplast.Cis-regulatory elements present in their promoters allowed to sort these transporters in different groups,also including specific TIPs and PIPs paralogs,and cohorts of cell wall-related genes.Together with simple thermodynamic considerations,these results lead to propose that H^(+)/sugar exchangers at the tonoplast,associated with a considerably acidic vacuolar pH,may exhaust cytosolic sugars in the flesh and alleviate the need for supplementary energisation of sugar transport at the plasma membrane.
文摘Correlated ion stopping arising from an intense cluster ion beam(CIB)interacting with an ultradense plasma target of relevance to inertial confinement fusion(ICF)is first investigated in a two-body approximation in an arbitrarily degenerate electron fluid target.The specific advantages of CIB-driven ICF are first demonstrated through 1D simulations,highlighting the very fine focusing of the ion beam on the target pellet.Then,theN-body configurations of ion debris resulting from the impact of heavy cluster ions are determined in terms of their specific topology.The validities of the usual assumptions of equal ion fragment charge and negligible coupling between stopping and Coulomb explosion are assessed.
文摘BACKGROUND Acute hand and wrist injuries are common and may lead to long-term disability if not managed adequately.Claims for negligence have been increasing in medical practice over the past few decades,with hand and wrist injuries and their treatment representing a significant percentage of orthopedic surgery lawsuits.There is no available literature regarding medical malpractice claims in hand and wrist injuries and surgery in Greece.AIM To identify claims related to hand and wrist trauma and surgery and to define the reasons of successful litigations.METHODS We performed a retrospective study of all legal claims of negligence for hand and upper extremity surgery that went to a trial,attributed to all surgical specialties,in Greece for a 20-year period.Data was further analyzed to identify claims related to hand and wrist trauma and surgery.RESULTS There were six malpractice claims related to hand and wrist trauma that ended in a trial.A missed diagnosis,which resulted in failure of initial management of the injury,was the main reason for a claim.Three of the six cases resulted in complete or partial loss of a finger.Two cases are still open,requiring an expert witness’s report,two cases were closed in favor of the defendant,and two cases were closed in favor of the plaintiff with a mean compensation of€2000(€1000-€3000).CONCLUSION Missed diagnosis was the main reason for a malpractice claim.Better understanding of factors leading to successful claims will help surgeons improve their practice to minimize legal implications and litigation.
基金supported by the National Key R&D Program of China under Grant 2016YFC0303901NSFC with grant numbers:U1606401,41476080,21276232 and 51377145+3 种基金Public Science and Technology Research Funds Projects of Ocean with grant number:201405036-2NSF of Zhejiang Province with grant number:LQ14D060004,LY13E070002 and 2014C33022Program for Zhejiang Leading Team of S&T Innovation with grant number:2013TD07Research Fund for the Taishan Scholar Project of Shandong Province with grant number:TSPD20161007
文摘A multi-electrode array is commonly applied in a plasma sparker to generate stable acoustic pulses.In this paper, the effects of the electrode configuration on the performance of a plasma sparker have been investigated. In terms of the load electrical characteristics, the electrode radius and distance have negligible influence on the electric characteristics, whereas a larger electrode number results in a smaller voltage and a larger current but has little effect on the load energy. Regarding the acoustic characteristics, both the expansion and collapse pulses can be increased by decreasing the electrode tip radius. the influence of the electrode number and electrode gap distance on the amplitude of the expansion pulse was found to be negligible. And the amplitude of the collapse pulse decreases significantly with increasing electrode number. Increasing the electrode number decreases the energy efficiency for intense bubble interactions, thus, a small electrode tip radius and a small electrode number are preferred for the design of a plasma sparker if the total discharge energy is given.
基金National Natural Science Foundation of China (No. 51606026)The Fundamental Research Funds for the Central Universities(DUT20LAB126)。
文摘The flame temperature in the combustor of a gas turbine is usually as high as 2000 K, while the maximum temperature that can be endured by metal materials is less than 1200 K at present. Therefore, various protective and cooling measures are needed to ensure the operation life of the liner wall which wraps the flame. The lean premixed combustor can meet the increasingly stringent emission requirements, but it requires more air for premixed combustion and then less air for cooling and dilution. In order to obtain a better impingement jet cooling structure, this paper studied the impingement jet cooling structure with vertical circular holes of equal diameter under single outlet condition. The structural variables studied include the jet hole diameter D, the impinging distance Z, the jet hole length(jet plate thickness) t, and the jet-to-jet spacing X is ignored. Among them, X/D(the ratio of the jet-to-jet spacing to the jet diameter) is inversely correlated with the mass flow rate. Within the constant X/D being equal to 10, the influence of D, Z and t on the average heat transfer coefficient h of the target surface under same mass flow was determined by means of conjugate numerical heat transfer analysis and orthogonal test. The results show that Z has significant influence on h, D has moderate influence on h, and t has negligible influence on h. Further, by means of regression orthogonal test, the influence trend of parameters Z and D on h at X/D=10 was studied. The optimal values of Z and D within the research scope were found.
基金Project supported by the science fund of the Chinese Academy of Sciences and the Ministry of Chemical Industry
文摘The intrinsic and global kinetics of methanol synthesis from carbon monoxide, carbon dioxide and hydrogen in the presence of C301 commercial catalyst is studied. The investigation is performed under typical commercial conditions in an isothermal plug-flow integral reactor and
文摘Two heat transfer parameters in the fixed bed,radial effective conductiviw k<sub>er</sub>,and wall heat transfer coefficient h<sub>w</sub>are estimated by using the method of orthogonal collocation and non-linear least square.The temperatures at forty collo-cation points distributed along the radial direction are measured simultaneously by means of multiehannel data logger.Theeffects of bed height,Re<sub>p</sub>,d<sub>t</sub>/d<sub>p</sub>,gas inlet temperature and wall temperature on k<sub>er</sub>and h<sub>w</sub> are studied.The results indicatethat the effect of gas inlet temperature and wall temperature is negligible.Bed height will only influence the parameter es-timations in shallow bed and at low Re<sub>p</sub>.Both k<sub>er</sub>and h<sub>w</sub> tend to reach a limit with increasing bed height.The asymptoticbed height which is independent of d<sub>p</sub> is about 0.5 m,while the asymptotic values of k<sub>er</sub>and h<sub>w</sub> increase with d<sub>p</sub>.The pa-rameters obtained with the wall being heated are about 10% lower than those with the wall being cooled.k<sub>er</sub>,h<sub>w</sub> and stag-nant contribution terms k<sub>er</sub>and h<sub>w</sub> are all related to dp·k<sub>er</sub>and h<sub>w</sub> estimated at the asymptotic bed height are correlated bythe following equations:k<sub>er</sub>=0.199+0.015 d<sub>t</sub>/d<sub>p</sub>+0.0020/(1+14.15(d<sub>p</sub>/d<sub>t</sub>)<sup>2</sup>)Re<sub>p</sub>h<sub>w</sub>=33.4+4.23d<sub>t</sub>/d<sub>p</sub>+0.333/(1+8.54(d<sub>p</sub>/d<sub>t</sub>)<sup>2</sup>)Re<sub>p</sub>(5.5【d<sub>t</sub>/d<sub>p</sub>【13)(100【Re<sub>p</sub>【500)
文摘It has been studied that the residence time distribution(RTD)function in a screw extruder in relation to that in thescrew and that in the die.For a complex flow field such as that between screw and die,it was supposed that the RTDfunction in the screw and that in the die were almost independent on each other.Therefore,a probabilistic method wasused to predict the RTD function in a complete extruder from that in the screw and that in the die.The experiments fordetermining the RTD were based on a stimulus-response technique.The results predicted,both in single-screw extruderand in twin-screw extruder,were in good agreement with those experimentally obtained.
基金Supported by the National Natural Science Foundation of China under Grant Nos 11875236,61575178,11574272 and U1832150the Zhejiang Provincial Natural Science Foundation under Grant Nos LY16A040014 and LY18A040001the Zhejiang Provincial Science and Technology Project under Grant No LGN18C200017
文摘Flipping of water dipoles in carbon nanotubes is of great importance in many physical and biological applications,such as signal amplification,molecular switches and nano-gates.Ahead of these applications,understanding and inhibiting the non-negligible thermal noise is essential.Here,we use molecular dynamics simulations to show that the flipping frequency of water dipoles increases with the rising temperature,and the thermal noise can be suppressed by imposed charges and external uniform electric fields.Furthermore,the water dipoles flip periodically between two equiprobable and stable states under alternating electric fields.These two stable states may be adopted to store 0 and 1 bits for memory storage or molecular computing.
基金Supported by the National Natural Science Foundation of China under Grant No.19575003。
文摘Correlation measurements of neutrons and fragments have been performed in a reaction of 33.4MeV/u ^(17)N on a ^(9)Be target.Energy spectra of n and nitrogen fragments were obtained at different angles.Based on the nuclear diffraction dissociation model,the measured energy spectra and the neutron angular distributions were reproduced quite well assuming that ^(17)N was composed of ^(16)N and n or ^(15)N and 2n interacting with the nonlocal separable potential.The satisfactory agreement between the theoretical calculations and the experimental data shows that the contribution of Coulomb dissociation is negligible in the reaction concerned.
基金Supported by the National Key Research and Development Program of China(Grant No.2016YFA0300803)the Open Research Fund of Jiangsu Provincial Key Laboratory for Nanotechnology+1 种基金the National Natural Science Foundation of China(Grant Nos.11774150 and 11874135)the Natural Science Foundation of Jiangsu Province of China(Grant No.BK20170627)。
文摘We report a perpendicular magnetic tunnel junction(p MTJ)cell with a tunnel magnetoresistance(TMR)ratio of nearly 200%at room temperature based on Co Fe B/Ta/Co Fe B as the free layer(FL)and a synthetic antiferromagnetic(SAF)multilayer[Pt/Co]/Ru/[Pt/Co]/Ta/Co Fe B as the reference layer(RL).The field-driven magnetization switching measurements show that the p MTJs exhibit an anomalous TMR hysteresis loop.The spin-polarized layer Co Fe B of SAF-RL has a lower critical switching field than that of FL.The reason is related to the interlayer exchange coupling(IEC)through a moderately thick Ta spacer layer among SAF-RLs,which generates a moderate and negative bias magnetic field on Co Fe B of RL.However,the IEC among RLs has a negligible influence on the current-driven magnetization switching of FL and its magnetization dynamics.
基金Supported by the National Basic Research Program of China(2010CB327600)the National Natural Science Foundation of China(61020106007,61077049)+1 种基金New Century Excellent Talents in University(NCET-08-0736)the 111 Program of China(B07005).
文摘The fabrication of self-catalyzed InP nanowires(NWs)is investigated under different growth conditions.Indium droplets induced by surface reconstruction act as nucleation sites for NW growth.Vertical standing NWs with uniform cross sections are obtained under optimized conditions.It is confirmed that the growth rate of NWs is strongly affected by the surface diffusion adatoms while contributions from the direct impingement of vapor species onto the In droplets can be negligible.The results indicate that the droplet acts as an adatom collector rather than a catalyst.Moreover,the diffusion flow rate of adatoms increases with time at the beginning of growth and stabilizes as the growth proceeds.
基金Supported by the Chinese National Nature Sciences Foundation(Grant No.69978019)the State Key Laboratory Foundation of Transient Optics Technology(Grant No.YAK20006)。
文摘The theory of the screening-photovoltaic solitons is improved in biased photorefractive-photovoltaic crystals.When the photovoltaic effect is negligible,the screening-photovoltaic solitons are the screening ones,and their space-charge field is the space-charge field of the screening solitons.If the external field is absent,the screening-photovoltaic solitons are the photovoltaic ones on the open-and closed-circuit conditions,and their space-charge field is of the photovoltaic solitons.We also show theoretically that the screening and the photovoltaic solitons on the open-and closed-circuit conditions may be studies together as the screening-photovoltaic solitons.
文摘Contrary to that without considering the hydrodynamic motion,the mass effect in the transverse momentum distribution of high energy nuclear collisions is/bund not negligible at high temperature after tie hydrodynamic motion is considered.So on the occasions for high temperature,such as the formation of quark-gluon-plasma,mass effect must be taken into account.