Craniocerebral injury promotes the repair of peripheral nerve injury

The increase in neurotrophic factors after craniocerebral injury has been shown to promote fracture healing. Moreover, neurotrophic factors play a key role in the regeneration and repair of peripheral nerve. However, whether craniocerebral injury alters the repair of peripheral nerve injuries remains poorly understood. Rat injury models were established by transecting the left sciatic nerve and using a free-fall device to induce craniocerebral injury. Compared with sciat- ic nerve injury alone after 6-12 weeks, rats with combined sciatic and craniocerebral injuries showed decreased sciatic functional index, increased recovery of gastrocnemius muscle wet weight, recovery of sciatic nerve ganglia and corresponding spinal cord segment neuron mor- phologies, and increased numbers of horseradish peroxidase-labeled cells. These results indicate that craniocerebral injury promotes the repair of peripheral nerve injury.

耳大神经移植修复面神经下颌缘支缺损

面神经下颌缘支是支配下唇方肌和三角肌等表情肌的重要神经,其损伤将造成下唇运动障碍、口角歪斜和鼓腮漏气等严重后果。目前对于面神经损伤缺损的修复主要有面神经直接缝合、神经替换术和神经移植术等。我科自2003年来对12例面神经下颌缘支缺损修复施行耳大神经移植修复,取得良好治疗效果。

Amniotic membrane covering for facial nerve repair

Amniotic membranes have been widely used in ophthalmology and skin injury repair because of their anti-inflammatory properties. In this study, we measured therapeutic efficacy and determined if amniotic membranes could be used for facial nerve repair. The facial nerves of eight rats were dissected and end-to-end anastomosis was performed. Amniotic membranes were covered on the anastomosis sites in four rats. Electromyography results showed that, at the end of the 3rd and 8th weeks after amniotic membrane covering, the latency values of the facial nerves covered by amniotic membranes were significantly shortened and the amplitude values were significantly increased. Compared with simple facial nerve anastomosis, after histopathological examination, facial nerve anastomosed with amniotic membrane showed better continuity, milder inflammatory reactions, and more satisfactory nerve conduction. These findings suggest that amniotic membrane covering has great potential in facial nerve repair.

Posterior interosseous nerve entrapment after Monteggia fracture-dislocation in children

在孩子与 Monteggia 破裂脱臼联系的神经损害的 ObjectiveAlthough 大多数是 neurapraxias 并且将在保守处理以后自发地恢复，深奥神经的外科的探索总是与以后的 interosseous 神经(大头针) 的陷阱在情况中被要求。然而，为为神经机能障碍的特定的模式的外科的干预的必要性和时间框架仍然保持争论。报告的目的由大头针损害是观察并且理解在孩子与 Monteggia 破裂脱臼联系的大头针损害的病理，并且为 nerveMethodsEight 案例，六个男孩和二个女孩的探索建议可能的指示，与 Monteggia 破裂脱臼复杂的，在 authors’ 起作用地设法从 2007 ～ 2008 的医院回顾地被考察。在他们收到了大头针的探索以前，所有病人经历了尝试的关上的减小，与开的减小，内部固定或成功的关上的 reduction.ResultsThe 大头针从 5 类型 III Bado’s Monteggia 破裂在 4 被发现被套住尖锐地以后到 radiocapitellar 关节。在留下的案例中，自从从损害有更长的时间间隔到操作，长期的压缩变化和光线的神经的 epineural 纤维变性被设想。在精神疲惫执行了的 microsurgical 以后，在神经功能的完全的恢复从这研究在 follow-up.ConclusionThe 调查结果期间在所有盒子中被获得建议那类型 III Monteggia 破裂脱臼与的每个盒子减少或肌肉的不在的功能由大头针刺激了，在孩子的一个无法缩减的光线的头应该为立即的外科的探索被看作一个指示深奥神经卡住陷阱排除一个潜力。