Construction of the underlying circRNA-miRNA-mRNA regulatory network and a new diagnostic model in ulcerative colitis by bioinformatics analysis

BACKGROUND Circular RNAs(circRNAs)are involved in the pathogenesis of many diseases through competing endogenous RNA(ceRNA)regulatory mechanisms.AIM To investigate a circRNA-related ceRNA regulatory network and a new predictive model by circRNA to understand the diagnostic mechanism of circRNAs in ulcerative colitis(UC).METHODS We obtained gene expression profiles of circRNAs,miRNAs,and mRNAs in UC from the Gene Expression Omnibus dataset.The circRNA-miRNA-mRNA network was constructed based on circRNA-miRNA and miRNA-mRNA interactions.Functional enrichment analysis was performed to identify the biological mechanisms involved in circRNAs.We identified the most relevant differential circRNAs for diagnosing UC and constructed a new predictive nomogram,whose efficacy was tested with the C-index,receiver operating characteristic curve(ROC),and decision curve analysis(DCA).RESULTS A circRNA-miRNA-mRNA regulatory network was obtained,containing 12 circRNAs,three miRNAs,and 38 mRNAs.Two optimal prognostic-related differentially expressed circRNAs,hsa_circ_0085323 and hsa_circ_0036906,were included to construct a predictive nomogram.The model showed good discrimination,with a C-index of 1(>0.9,high accuracy).ROC and DCA suggested that the nomogram had a beneficial diagnostic ability.CONCLUSION This novel predictive nomogram incorporating hsa_circ_0085323 and hsa_circ_0036906 can be conveniently used to predict the risk of UC.The circRNa-miRNA-mRNA network in UC could be more clinically significant.

Intelligent Network-Connected New Energy Vehicle Technology and Application Under the Dual-Carbon Strategy

In responding to the“dual carbon”strategy,intelligent networked new energy vehicle technology plays a crucial role.This type of vehicle combines the advantages of new energy technology and intelligent network technology,effectively reduces carbon emissions in the transportation sector,improves energy utilization efficiency,and contributes to the green transportation system through intelligent transportation management and collaborative work between vehicles,making significant contributions.This article aims to explore the development of intelligent network-connected new energy vehicle technology and applications under the dual-carbon strategy and lay the foundation for the future development direction of the automotive industry.

Learning Bayesian network parameters under new monotonic constraints

When the training data are insufficient, especially when only a small sample size of data is available, domain knowledge will be taken into the process of learning parameters to improve the performance of the Bayesian networks. In this paper, a new monotonic constraint model is proposed to represent a type of common domain knowledge. And then, the monotonic constraint estimation algorithm is proposed to learn the parameters with the monotonic constraint model. In order to demonstrate the superiority of the proposed algorithm, series of experiments are carried out. The experiment results show that the proposed algorithm is able to obtain more accurate parameters compared to some existing algorithms while the complexity is not the highest.

网络新媒体视阈下客家议题在日传播特征分析——基于日本Google News的考察

以日本Google News中的客家相关日文报道为语料,通过文本挖掘工具KH Coder进行文本数据挖掘,发现日本网络新闻媒体的客家议题日文报道具有分布零散性及以图片报道为主的特点。报道关注的客家区域主要涉及台湾地区、福建、香港地区、广东等地,其中,台湾地区的客家关注度最高。报道聚焦客家的观光旅游、产业振兴、客家书籍出版等相关内容,形成了客家传统建筑类、台湾地区客家文化交流类、客家文学作品推介类、客家观光旅游类等四大主要议题。本文提出要充分运用Google News等网络新媒体强大的技术功能和传播优势加大客家文化的传播力度。

New Media, Public Sphere, and Arab Spring： Demystifying the Power of Social Networks

This paper looks at the new media, communication, and political environment in both Tunisia and Egypt during and after the revolution. The new environment provided activists, politicians, civil society, and youth among others, who want to express their opinions and share their views, with various channels and means of corranunication to be part of the political action and to participate in the decision-making process. Social media played an important role in mobilizing youth to rally and protest. This is to say that a new model of communication has emerged with this new environment. The receiver has become the sender and the producer of the message. The process of communication, therefore, has been changed from one to many to from many to many, and everybody became sender and receiver at the same time. The main research question this paper aims to answer is： Are social networks enough to change the political and economic scene in the Arab World？ And is there a relationship between the new communication environment and Arab spring？ The year 2011 has been in the Arab world the year of social networks and radical changes in the political scene where a score of dictators were ousted. New political communication networks and mechanisms took place, and for the first time in Arab political communication, public opinion was a major political player. Social networks helped tremendously the formation of new public sphere where the public finds its way in the media and communication processes. At their best, new media can mobilize crowds and masses to rally and protest. They can give a social perspective to movements. However, they can＇t make change and implement democracy. After the collapse of the regimes in Tunisia and Egypt, things are not getting any better. There is no democratic transition, and both countries are experiencing complex economic, social, and political problems.

Research on the New Mode of college students’mental Health Education under the Network environment

With the rapid development of science andtechnology, internet technology has become matureincreasingly. It has become an important part ofpeople’s work, life and study. At the same time, thenetwork environment has also brought an impact onthe physical and mental health of college students.Nowadays, the quality and level of college students’mental health education has become society topics.College psychological health education work shouldkeep pace with the network environment developmentand the students’ physical and mental development.It is the effective innovation of psychological healtheducation work. The new model of college students’psychological health education development isconstructed. It is improve the level of students’ physicaland mental health development, and the psychologicalquality of college students is strengthen. Based onthis, this paper analyzes the existing problems on thecollege students’ mental health development. Under thenetwork environment, it proposes an effective method toconstruct a new mode of college students’ mental healtheducation .

ZTE Softswitch the Working Solution to Build the New Generation Network

ZTE Softswitch supports the interoperability and convergence oflegacy PSTN/ISDN, PLMN, IN, and the Internet, allowing operatorsor service providers to offer diversified services to any subscriber atany time on a ZTE Softswitch network.With powerful C4 and C5 features, ZTE Softswitch effectivelysolves the evolution problems in the existing networks, protectinglegacy network investment and reducing future investment to a prof-itable level for providers.

New International Partner Network Launched to Further Sino-US Business Relations

"The network will foster newrelationship between US andChinese small and medium-size companies in 14 key busi-ness centers, generating newopportunities for US SMEs inthe China market and prosper-ity for both our great nations,"said Tim Hauser.

ZTE Debuts New Generation IPTN Bearer Network Solution

ZTE Corporation announced the formal launch of its new generation IPTN bearer network solution targeting mobile backhaul and multi-service delivery to meet the needs of IP-based services on August 27,2009.It features packet

ZTE Cloud Radio Solution to Usher in New Era of High-Performance LTE Networks

ZTE showcased its innovative cloud radio solution for 4G network optimization at the Mobile Asia Expo in Shanghai.

On the English translation of the network new and hot words from the perspective of lexicology

From the initial sparks of fire to the present independent school, the network language has become the research object of many language scholars. With the rapid development of the lntemet, a large number of the network new words and hot words have a rapid impact on people＇s social communication and their life. This kind of the vocabularies truly reflects the different life attitudes and cultures mainly with the words as the carrier, and then shows the network cultures, mentalities and life styles of the Chinese people, and especially the young people in different stages. From the perspective of the English vocabulary, take the reverse into consideration of the reaction of the network new and hot words on the present situations of the life of young people, the latest social phenomena and the importance and particularity of the new things, and we can find out the roles and values of the network new and hot words in the intercultural communication.

ZTE Boosts European Presence with New Network Operation Centre in Budapest

8 May 2012, Budapest -- ZTE Corporation announced that Hungarian Minister of Economics, Gy^irgy Matolcsy, and ZTE senior vice president, Zhu Jinyun have signed an agreement to cooperate on the establishment of ZTE＇s new European Regional Network Operation Center in Budapest.

LESSONS FROM EUROPE FOR CHINA?New Urban Sub-Centres for a Polycentric Network City

This paper compares two cases:It relates to the development of new urban sub-centres in China,and the relationship of these sub-centres to‘Network City’theory.As cities move towards more polycentric systems,the case of Potsdamer Platz Berlin,compared to Zhenru Sub-Centre in Shanghai,is discussed.Both are transport-oriented developments promoting mixed-use density and transport-oriented development.According to the documentation by Shanghai municipality,this new urban centre,which is currently in its planning phase,is supposed to become a‘sustainable sub-centre for a growing metropolis.’The author,who has intimate knowledge of the Berlin case,was asked to advice on the Chinese project,based on the Potsdamer Platz experience.After some hesitation,a series of careful recommendations were formulated for the design and development of the Zhenru Sub-Centre,knowing that it is rather difficult to translate from one case to the other.The conclusion includes five recommendations for the urban design of such sub-centres,to ensure a delivery of economical,social and environmental sustainable outcomes.

Networking of BeiDou Navigation Satellite System Accelerated with Two New Members

At 4:50 on April 30, China's LM-3B/I rocket, an improved type based on LM-3B, made its debut at the Xichang Satellite Launch Center and successfully sending the 12th and 13th BeiDou Navigation Satellite System satellites into the planned transfer orbit in space. It was the first time that China launched two BeiDou satellites with one rocket. It was

Applying Network Technology to Improve TV News Production Mode

With the development of database and computer network technology, traditional TV news production mode (TVNPM) faces great challenge. Up to now, evolution of TVNPM has experienced two stages: In the beginning, TV news is produced completely by hand, named as pipelining TVNPM in this paper. This production mode is limited to space and time, so its production cycle is very time-consuming, and it requires a lot of harmony in different departments; Subsequently, thanks to applications of database technology, a new TVNPM appears, which is named as pooled information resource TVNPM. Compared with pipelining TVNPM, this mode promotes information sharing. However, with the development of network technology, especially the Intranet and the Internet, the pooled information resource TVNPM receives strong impact, and it is referred to contrive a new TVNPM. This new TVNPM must support information sharing, remote collaboration, and interaction in communications so as to improve group work efficiency. In this paper, we present such a new TVNPM, namely, Network TVNPM, give a suit of system solution to support the new TVNPM, introduce the new workflow, and in the end analyze the advantages of Network TVNPM.

Present situation and prospects of forest ecological network in Jilin Province, China

This paper makes a brief introduction of the ecological environment, forestry achievements, and the existing questions of Jilin Province. The task of forest ecological network and eight questions demanding prompt solution were discussed based on the present situation of forestry in Jilin Province. The author also made prospects for future application of bio-technique, infor-mation technology, new material technology and nuisance-free forest health technology in forest ecological network.

一种适用于异构网络的TCP New Vegas算法

TCP Vegas是运输层的一种可靠算法,但是在无线网络中不能最高效率的占用网路带宽,使得数据传输受到限制,不适合在无线网络中传输。对TCP Vegas算法进行改进,提出了一种适用于异构网络的TCP New Vegas算法。该算法将diff控制在两个动态门限值a,b之间,根据a,b两个动态门限值的设定,可有效的提高算法的拥塞窗口及吞吐量。以无线传感器网络接入第三代移动通信网络为仿真背景,对该算法进行了仿真实验。仿真结果表明,改进后的TCP New Vegas算法具有较大的拥塞窗口和较高的吞吐量,更适合应用于异构网络中数据的传输。

消失的“受害者”:难民新闻图像的全球生产机制及其传播网络

作为重大事件的叙事载体,新闻图像在推动国际议题的全球传播中发挥着重要作用。针对全球危机的直接后果——难民议题,对198个国家的474786张难民图像进行视觉框架提取、人物情感识别和传播网络分析后发现:全球难民新闻图像的视觉呈现具有符号偏离、情感对立与叙事矛盾等特点,这种视觉话语冲突受到经济、政治、宗教文化等语境因素的影响;全球媒体在难民图像共享上呈现较强的联动效应,形成显著的圈层结构和媒体群落。由此,国际议题自身属性为图像生产的场景化提供了条件,国家内部语境因素是其图像生产策略的主要线索,国际权力则是构建全球视觉传播生态的底层逻辑。

略论新时代高校网络意识形态安全的风险挑战与应对策略

高校意识形态安全作为国家安全的重要方面,对培养社会主义事业合格建设者和可靠接班人,确保高校坚持社会主义办学方向尤为重要。新时代高校网络意识形态安全面临着西方敌对势力渗透、错误社会思潮干扰、信息传播圈层化阻隔等诸多挑战。为有效应对这些风险挑战,高校亟需强化价值引领,提高抵御风险能力;建强工作队伍,构建协同育人格局;加强网络管理,营造清朗网络环境;创新方式方法,提升青年网络安全素养。

基于Internetwork的电视新闻信息系统

本文提出了一个基于互联网的电视新闻信息系统的实现方法。文中描述了该网络的拓扑结构及联接互联网的方法。该系统具有文稿的录入、编辑、查询、打印、编排和统计功能。