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Ex vivo 3D osteocyte network construction with primary murine bone cells 被引量:2
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作者 Qiaoling Sun Yexin Gu +3 位作者 Wenting Zhang Leah Dziopa Jenny Zilberberg Woo Lee 《Bone Research》 SCIE CAS CSCD 2015年第3期152-163,共12页
Osteocytes reside as three-dimensionally(3D) networked cells in the lacunocanalicular structure of bones and regulate bone and mineral homeostasis. Despite of their important regulatory roles, in vitro studies of os... Osteocytes reside as three-dimensionally(3D) networked cells in the lacunocanalicular structure of bones and regulate bone and mineral homeostasis. Despite of their important regulatory roles, in vitro studies of osteocytes have been challenging because:(1) current cell lines do not sufficiently represent the phenotypic features of mature osteocytes and(2) primary cells rapidly differentiate to osteoblasts upon isolation. In this study, we used a 3D perfusion culture approach to:(1) construct the 3D cellular network of primary murine osteocytes by biomimetic assembly with microbeads and(2) reproduce ex vivo the phenotype of primary murine osteocytes, for the first time to our best knowledge. In order to enable 3D construction with a sufficient number of viable cells, we used a proliferated osteoblastic population of healthy cells outgrown from digested bone chips. The diameter of microbeads was controlled to:(1) distribute and entrap cells within the interstitial spaces between the microbeads and(2) maintain average cell-to-cell distance to be about 19 mm. The entrapped cells formed a 3D cellular network by extending and connecting their processes through openings between the microbeads. Also, with increasing culture time, the entrapped cells exhibited the characteristic gene expressions(SOST and FGF23) and nonproliferative behavior of mature osteocytes. In contrast, 2D-cultured cells continued their osteoblastic differentiation and proliferation. This 3D biomimetic approach is expected to provide a new means of:(1) studying flow-induced shear stress on the mechanotransduction function of primary osteocytes,(2) studying physiological functions of 3D-networked osteocytes with in vitro convenience,and(3) developing clinically relevant human bone disease models. 展开更多
关键词 CELL FIGURE Ex vivo 3D osteocyte network construction with primary murine bone cells BONE
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A DATA MINING METHOD BASED ON CONSTRUCTIVE NEURAL NETWORKS 被引量:4
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作者 Wang Lunwen Zhang Ling 《Journal of Electronics(China)》 2007年第1期133-137,共5页
In this letter,Constructive Neural Networks (CNN) is used in large-scale data mining. By introducing the principle and characteristics of CNN and pointing out its deficiencies,fuzzy theory is adopted to improve the co... In this letter,Constructive Neural Networks (CNN) is used in large-scale data mining. By introducing the principle and characteristics of CNN and pointing out its deficiencies,fuzzy theory is adopted to improve the covering algorithms. The threshold of covering algorithms is redefined. "Extended area" for test samples is built. The inference of the outlier is eliminated. Furthermore,"Sphere Neighborhood (SN)" are constructed. The membership functions of test samples are given and all of the test samples are determined accordingly. The method is used to mine large wireless monitor data (about 3×107 data points),and knowledge is found effectively. 展开更多
关键词 Data mining Neural networks Constructive Neural networks (CNN) Wireless monitoring
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Discussion on Construction of CDMA2000 1xEV-D0 Network
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作者 Gu Minxia (Technology Department of China Unicorn Corporation Ltd.,Beijing 100032,China) 《ZTE Communications》 2003年第2期11-12,共2页
The research advances on 3G CDMA standards are outlined and the network architecture and networking characteristics of CD- MA2000 1x EV-DO and CDMA2000 1x EV-DV are described.Em- phasis is put on the key technical iss... The research advances on 3G CDMA standards are outlined and the network architecture and networking characteristics of CD- MA2000 1x EV-DO and CDMA2000 1x EV-DV are described.Em- phasis is put on the key technical issues that may occur when China Unicom upgrades CDMA2000 1x to CDMA2000 1x EV-DO. 展开更多
关键词 CDMA it for as in Discussion on construction of CDMA2000 1xEV-D0 Network of on
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Quick Construction of Profitable Elaborate WCDMA Network in 3G Times
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作者 Chen Yong (Mobile Division of ZTE Corporation, Shanghai 201203, China) 《ZTE Communications》 2005年第2期34-36,共3页
关键词 WCDMA Quick construction of Profitable Elaborate WCDMA Network in 3G Times
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Construction and Upgrade of Urban Power Grids:Achievements and Tasks
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作者 本刊编辑部 《Electricity》 2001年第1期19-21,共3页
The significant achievements in construction and upgrade of China’s urban grids in the past two years and more are enumerated with respect to scale of grids, configuration of medium-and high-voltage grids, technical ... The significant achievements in construction and upgrade of China’s urban grids in the past two years and more are enumerated with respect to scale of grids, configuration of medium-and high-voltage grids, technical and localizing level of equipment, as well as social and economic benefits. At the same time, the new tasks for the year 2001 is put forth for volume of investment to be completed, projects progressing and operating benefit indexes, etc. 展开更多
关键词 urban network construction urban network upgrade operating benefit indexes
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The Urban and Rural Network Construction and Retrofit Projects Has Gained Great Progress
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《Electricity》 2000年第2期48-48,共1页
关键词 The Urban and Rural Network construction and Retrofit Projects Has Gained Great Progress
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Research and Design of Network Management Construction Based on Mobile AGENT
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作者 Yuan-Hui Yu 《Journal of Electronic Science and Technology of China》 2007年第3期215-217,共3页
The technical characters of mobile agent (MA) originated in the distributional artificial intelligence domain is introduced. A network management construction based on agent (NMCA) is then proposed. The NMCA struc... The technical characters of mobile agent (MA) originated in the distributional artificial intelligence domain is introduced. A network management construction based on agent (NMCA) is then proposed. The NMCA structure features are elaborated in detail. A prototype design of NMCA is given by using the jKQML programming. The establishment of NMCA platform will be helpful to reduce the correspondence load of network management and improves the efficiency and the expansion ability of network management systems. 展开更多
关键词 HARBOR manage center monitored node network management construction based on agent.
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The Largest Thermal Power Unit in Northwest Network Starts Construction Soon
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《Electricity》 1997年第3期50-50,共1页
关键词 The Largest Thermal Power Unit in Northwest Network Starts construction Soon
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Multi-Zone-Wise Blockchain Based Intrusion Detection and Prevention System for IoT Environment
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作者 Salaheddine Kably Tajeddine Benbarrad +1 位作者 Nabih Alaoui Mounir Arioua 《Computers, Materials & Continua》 SCIE EI 2023年第1期253-278,共26页
Blockchain merges technology with the Internet of Things(IoT)for addressing security and privacy-related issues.However,conventional blockchain suffers from scalability issues due to its linear structure,which increas... Blockchain merges technology with the Internet of Things(IoT)for addressing security and privacy-related issues.However,conventional blockchain suffers from scalability issues due to its linear structure,which increases the storage overhead,and Intrusion detection performed was limited with attack severity,leading to performance degradation.To overcome these issues,we proposed MZWB(Multi-Zone-Wise Blockchain)model.Initially,all the authenticated IoT nodes in the network ensure their legitimacy by using the Enhanced Blowfish Algorithm(EBA),considering several metrics.Then,the legitimately considered nodes for network construction for managing the network using Bayesian-Direct Acyclic Graph(B-DAG),which considers several metrics.The intrusion detection is performed based on two tiers.In the first tier,a Deep Convolution Neural Network(DCNN)analyzes the data packets by extracting packet flow features to classify the packets as normal,malicious,and suspicious.In the second tier,the suspicious packets are classified as normal or malicious using the Generative Adversarial Network(GAN).Finally,intrusion scenario performed reconstruction to reduce the severity of attacks in which Improved Monkey Optimization(IMO)is used for attack path discovery by considering several metrics,and the Graph cut utilized algorithm for attack scenario reconstruction(ASR).UNSW-NB15 and BoT-IoT utilized datasets for the MZWB method simulated using a Network simulator(NS-3.26).Compared with previous performance metrics such as energy consumption,storage overhead accuracy,response time,attack detection rate,precision,recall,and F-measure.The simulation result shows that the proposed MZWB method achieves high performance than existing works. 展开更多
关键词 IOT multi-zone-wise blockchain intrusion detection and prevention system edge computing network graph construction IDS intrusion scenario reconstruction
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The 5C Model of Linguistic Creativity:Construction Grammar as a Cognitive Theory of Verbal Creativity
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作者 Thomas HOFFMANN 《Journal of Foreign Languages and Cultures》 2024年第1期139-154,共16页
Creativity is a design feature of human language.This paper presents a cognitive model of verbal creativity that draws on insights from the psychological research into creativity-particularly Glaveanu's 5A model t... Creativity is a design feature of human language.This paper presents a cognitive model of verbal creativity that draws on insights from the psychological research into creativity-particularly Glaveanu's 5A model that distinguishes five crucial perspectives on a creative act(actors,audience,artefacts,actions and affordances).The paper will outline a linguistic version of this model that adopts Construction Grammar as its theoretical foundation.The resulting"5C model of constructional creativity"argues that the central elements of linguistic creativity are constructors,co-constructors,constructs,constructional blending and the constructional network. 展开更多
关键词 CREATIVITY construction grammar cognitive linguistics BLENDING 5C model of constructional creativity COGNITION constructional networks
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Present situation and prospects of forest ecological network in Jilin Province, China 被引量:1
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作者 王宪成 《Journal of Forestry Research》 SCIE CAS CSCD 2002年第4期323-326,338,共4页
This paper makes a brief introduction of the ecological environment, forestry achievements, and the existing questions of Jilin Province. The task of forest ecological network and eight questions demanding prompt solu... This paper makes a brief introduction of the ecological environment, forestry achievements, and the existing questions of Jilin Province. The task of forest ecological network and eight questions demanding prompt solution were discussed based on the present situation of forestry in Jilin Province. The author also made prospects for future application of bio-technique, infor-mation technology, new material technology and nuisance-free forest health technology in forest ecological network. 展开更多
关键词 Forest Ecology Network construction Jilin Province Forestry Development Forest management New technology
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A technical review on persistent scatterer interferometry 被引量:1
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作者 Hongguo Jia Luyao Liu 《Journal of Modern Transportation》 2016年第2期153-158,共6页
This article focuses on reviewing the technologies of persistent scatterer interferometry (PSI), which has been often used to monitor the deformation of Earth surface. Three critical steps in the implementation of P... This article focuses on reviewing the technologies of persistent scatterer interferometry (PSI), which has been often used to monitor the deformation of Earth surface. Three critical steps in the implementation of PSI were introduced, i.e., (1) detection of persistent scatterer (PS), (2) construction of PS network, and (3) PSI modeling and solution. Finally, the main problems and outlooks on the PSI technique are discussed and given. 展开更多
关键词 Review - Persistent scatterer interferometry (PSI) PS detection PS network construction PSI modeling and solution
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Study on Adoption of 750 kV Voltage Class in Northwest China Power Network
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作者 钱家骧 王森 《Electricity》 2001年第4期12-15,共4页
This paper introduces the selection and scheme demonstration of higher voltage class in Northwest ChinaPower Network, and conclusions made by main research institutes and experts’ comments.[
关键词 power network planning power network construction feasibility study 750 kV extra-high voltage
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Interconnection Project of Fujian Power Grid With East China Power Network Formally Started to Construct
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《Electricity》 2000年第2期55-55,共1页
关键词 Project Interconnection Project of Fujian Power Grid With East China Power Network Formally Started to Construct
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Optimal blockchain network construction methodology based on analysis of configurable components for enhancing Hyperledger Fabric performance 被引量:2
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作者 Lei Hang Do-Hyeun Kim 《Blockchain(Research and Applications)》 2021年第1期29-40,共12页
Presently,blockchain technology has been widely applied in various application domains such as the Internet of Things(IoT),supply chain management,healthcare,etc.So far,there has been much confusion about whether bloc... Presently,blockchain technology has been widely applied in various application domains such as the Internet of Things(IoT),supply chain management,healthcare,etc.So far,there has been much confusion about whether blockchain performs with scale,and admittedly,a lack of information about best practices that can improve the performance and scale.This paper proposes a novel blockchain network construction methodology to improve the performance of Hyperledger Fabric.As a highly scalable permissioned blockchain platform,Hyperledger Fabric supports a wide range of enterprise use cases from finance to governance.A comprehensive evaluation is performed by observing various configurable network components that can affect the blockchain performance.To demonstrate the significance of the proposed methodology,we set up the experiment environment for the baseline and the test network using optimized parameters,respectively.The experimental results indicate that the test network's performance is enhanced effectively compared to the baseline in transaction throughput and transaction latency. 展开更多
关键词 Blockchain performance Network construction methodology Configurable network components Permissioned blockchain
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Enhancing electromagnetic wave absorption in carbon fiber using FeS_(2)nanoparticles 被引量:8
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作者 Yuying Guo Meng Zhang +9 位作者 Tingting Cheng Yuxin Xie Laibin Zhao Liang Jiang Wenxin Zhao Liying Yuan Alan Meng Jian Zhang Ting Wang Zhenjiang Li 《Nano Research》 SCIE EI CSCD 2023年第7期9591-9601,共11页
Carbon-based electromagnetic wave absorbing materials(absorbers)adhered with metallic sulfide nanoparticles of good electrical conductivity attract increasing researchers’attention.In this study,on the basis of carbo... Carbon-based electromagnetic wave absorbing materials(absorbers)adhered with metallic sulfide nanoparticles of good electrical conductivity attract increasing researchers’attention.In this study,on the basis of carbon fiber(C_(f))@Fe_(3)O_(4) nanocomposites obtained by the electrostatic spinning and reflow method,C_(f)@FeS_(2)nanocomposite was successfully prepared during a further hydrothermal process.The products exhibit excellent electromagnetic wave absorption performances with a minimum reflection loss(RLmin)of-54.11 dB at 2.13 mm matching thickness.At the same time,the optimal effective absorption bandwidth(EAB)value of 6.04 GHz at a thickness of 1.98 mm covers the whole Ku band,suggesting its excellent electromagnetic wave absorption performances.In addition,the interlaced network structure constructed by carbon fiber,outstanding conductivity of FeS_(2)nanoparticles,and interfacial polarization from hetero-structure play significant parts in enhancing the electromagnetic parameters and absorption performances.All these results suggest that the C_(f)@FeS_(2)nanocomposites can be taken as a new electromagnetic wave-absorbing material under their low density,simple craft,and strong absorption characteristics. 展开更多
关键词 constructed network structure carbon fiber(C_(f))@FeS_(2)nanocomposite enhanced dielectric loss microwave attenuation mechanism
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Exploring the Pharmacological Mechanism of Danhe Granules against Hyperlipidemia by Means of Network Pharmacology and Verified by Preliminary Experiments 被引量:2
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作者 Zhi-Qing Zhang Ai-Ping Chen +4 位作者 Tong Yu Shuang-Jie Yang De-Shuai Yu Ran Yang Xin-Lou Chai 《World Journal of Traditional Chinese Medicine》 2021年第4期436-444,共9页
Objective:This study explored the multicomponent,multitarget,and multipathway mechanism of Danhe granules(DG)against hyperlipidemia through network pharmacology.The relevant targets and pathways were verified by preli... Objective:This study explored the multicomponent,multitarget,and multipathway mechanism of Danhe granules(DG)against hyperlipidemia through network pharmacology.The relevant targets and pathways were verified by preliminary experiments.Methods:The active components of DG were selected by TCMSP and TCMIP database,and the component-target network diagram was constructed by Cytoscape 3.7.1.The protein–protein interaction network of targets was constructed and core targets were screened out by STRING11.0 database.Metascape database and Cytoscape 3.7.1 were used to enrich the target and establish a hyperlipidemia model in Sprague-Dawley(SD)rats to detect blood lipid and oxidative stress indexes and observed pathological changes of aorta by H and E staining.Results:The results showed that a total of seven active components of DG were screened out,including quercetin,sitosterol,luteolin,kaempferol,etc.There were 127 corresponding targets,including AKT1,tumor necrosis factor,TP53,interleukin-6,RELA,vascular endothelial growth factor,superoxide dismutases,and catalase.It is mainly involved in biological processes such as drug response,regulation of apoptosis,redox reaction,and lipid reaction.There were 573 signal pathways corresponding to the target,including HIF-1 signal pathway,TNF signal pathway,VEGF signal pathway,nonalcoholic fatty liver disease,etc.The experiment verified that DG can reduce the blood lipid of SD rats by regulating the process of oxidative stress.Conclusions:This study made a preliminary study on the pharmacological mechanism of DG against hyperlipidemia and laid the foundation for the research and development of new drugs and subsequent in-depth research. 展开更多
关键词 Component-target network construction Danhe granules HYPERLIPIDEMIA network pharmacology oxidative stress
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The Review of China Post's Informationizing Constructing 被引量:1
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作者 WANG Wei-min DU Yu-wei SUN Hao 《The Journal of China Universities of Posts and Telecommunications》 EI CSCD 2005年第3期101-104,共4页
The article briefly introduces the three stages that China Post experienced and the circumstances of the fundamental network construction, focusing on introducing the three sorts of services based on postal comprehens... The article briefly introduces the three stages that China Post experienced and the circumstances of the fundamental network construction, focusing on introducing the three sorts of services based on postal comprehensive computer network's applicable software system : postal financial service ; traditional service electrified ; electronic postal service. Finally the thinking for future China Post's informationizing constructing is put forward. 展开更多
关键词 Post informationizing postal comprehensive computer network fundamental network construction software system application
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Research on Classification of Development Level in China's Postal Communication
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作者 Wang Weimin(Shijiazhuang Postal College, ShijiaZhuang 050021, P. R. China) 《The Journal of China Universities of Posts and Telecommunications》 EI CSCD 1996年第2期58-61,共4页
in this poper the unbalance of development level in China's postal communication is discussed,classified into four types by Cluster Analysis Method, and the suggestion on postal service and postal network based on... in this poper the unbalance of development level in China's postal communication is discussed,classified into four types by Cluster Analysis Method, and the suggestion on postal service and postal network based on the different conditions of each type is made. 展开更多
关键词 s: cluster analysis CLASSIFICATION postal service development construction of postal network
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