The aim of this study is to describe the presence of neuroendocrine(NE) cells (paraneurons), producing biogenic amines and/orpeptidergic hormones, in the female urethra of wild mainmals, by means of histochemical and ...The aim of this study is to describe the presence of neuroendocrine(NE) cells (paraneurons), producing biogenic amines and/orpeptidergic hormones, in the female urethra of wild mainmals, by means of histochemical and double labeling immunofluoresent techniques. 5-Hydroxytrytamine-. chromogranin A-, cholecystokinin- and somatostatin-contain NE cells are present in the urethral epithelium of all the species studied. Paraneurons containing 5-hydrxytryptamine colocalized with chromogranin A or cholecystokinin were also found in all subjects. Such active substances are hypothesized to play a role in the contretion of the urethral musculature, emission of urogenital fluids, and inhibition of endocrine and exocrine secretions.展开更多
文摘The aim of this study is to describe the presence of neuroendocrine(NE) cells (paraneurons), producing biogenic amines and/orpeptidergic hormones, in the female urethra of wild mainmals, by means of histochemical and double labeling immunofluoresent techniques. 5-Hydroxytrytamine-. chromogranin A-, cholecystokinin- and somatostatin-contain NE cells are present in the urethral epithelium of all the species studied. Paraneurons containing 5-hydrxytryptamine colocalized with chromogranin A or cholecystokinin were also found in all subjects. Such active substances are hypothesized to play a role in the contretion of the urethral musculature, emission of urogenital fluids, and inhibition of endocrine and exocrine secretions.
