Dear Editor, I would like to offer some comments on the excellent article by Hai-Yan He and colleagues published in Genomics, Proteomics & Bioinformatics on 1st April 2017 [1]. The authors include, in the list of gen...Dear Editor, I would like to offer some comments on the excellent article by Hai-Yan He and colleagues published in Genomics, Proteomics & Bioinformatics on 1st April 2017 [1]. The authors include, in the list of genetic polymorphisms that have an effect on vita- mins, the low concentrations of cellular and plasma vitamin B12 in GG carriers of SNP rs602662 (772 G 〉 A) in the gene encoding fucosyltransferase 2 (FUT2).展开更多
Dear Editor, We thank the author for making meaningful comments on our recent article [1]. The SNP 772G 〉 A (rs602662) in exon 2 of the gene encoding fucosyl transferase (FUT2) has been found to be related with t...Dear Editor, We thank the author for making meaningful comments on our recent article [1]. The SNP 772G 〉 A (rs602662) in exon 2 of the gene encoding fucosyl transferase (FUT2) has been found to be related with the alterations in plasma vitamin B12 levels. GG carriers possessed lower levels of vitamin B12. However, we didn't know the mechanism behind this association.展开更多
文摘Dear Editor, I would like to offer some comments on the excellent article by Hai-Yan He and colleagues published in Genomics, Proteomics & Bioinformatics on 1st April 2017 [1]. The authors include, in the list of genetic polymorphisms that have an effect on vita- mins, the low concentrations of cellular and plasma vitamin B12 in GG carriers of SNP rs602662 (772 G 〉 A) in the gene encoding fucosyltransferase 2 (FUT2).
基金supported by grants from the National Key Research and Development Program(Grant No.2016YFC0905000)National High-tech R&D Program of China(863 Program+2 种基金Grant No.2012AA02A518)National Natural Scientific Foundation of China(Grant Nos.81522048,81573511,81273595)the Innovation-driven Project of Central South University,China(Grant No.2016CX024)
文摘Dear Editor, We thank the author for making meaningful comments on our recent article [1]. The SNP 772G 〉 A (rs602662) in exon 2 of the gene encoding fucosyl transferase (FUT2) has been found to be related with the alterations in plasma vitamin B12 levels. GG carriers possessed lower levels of vitamin B12. However, we didn't know the mechanism behind this association.