Objective To know the growth of the cerebellum in newborn infants. Methods The centraivermian area (CVA) of the cerebellum was measured by head ultrasonography in 90 newborns including 65full - terms, 14 preterms and ...Objective To know the growth of the cerebellum in newborn infants. Methods The centraivermian area (CVA) of the cerebellum was measured by head ultrasonography in 90 newborns including 65full - terms, 14 preterms and 11 small for gestational age infants (SGA). Results The average age of the newborninfants were 4.7d (3~7d). The mean CVA in full-terms was 5.81±0.8cm2, which was significantly greater thanthat in preterms (3.7±1.0cm2), and SGA (5.1±0.8cm2), respectively. However, when corrected for birth weight(BW), the ratio of CVA/BW in term SGA was 2.07, being signoficantly higher than the ratio of 1.72 in normalfull- term newborns. There was no dillerence between male and female infants. Statistically significantrelationships were lound between CVA and BW (r=0.8129, P<0.01) and between CVA and gestational age(r=0.7450, P<0.01). Conclusion The study provide some understanding on the grouth of the cerebellum, and thecerebellar measurement by cranial ultrasound is helpful for the assessment of neurological maturation in newborninfants.展开更多
The prefrontal cortex of a human full termnewborn infant just after accidental death was studies by mcans of immunocytochemical technique with antibody directedagainst GABA(Immunonuclear Corp.)and ABC kit(Vector)。GAB...The prefrontal cortex of a human full termnewborn infant just after accidental death was studies by mcans of immunocytochemical technique with antibody directedagainst GABA(Immunonuclear Corp.)and ABC kit(Vector)。GABA-containing neurons were found over all layers and all were nonpyramidal cells.The laminar distribution of GABA-containing ne-urons was not even between different layers,density in laye Ⅱ was prominently higher than any other layers,density in layer Ⅲ and layer Ⅳ was higher than that in layer V and Ⅵ.展开更多
There are around 15 million preterm newborns(PT) eve ry year(Atienza-Navarro et al., 2020).With these figures in mind,prematurity represents a major health problem worldwide and it is a leading cause of infant mortali...There are around 15 million preterm newborns(PT) eve ry year(Atienza-Navarro et al., 2020).With these figures in mind,prematurity represents a major health problem worldwide and it is a leading cause of infant mortality,accounting for up to 35%of all deaths among newborns(Atienza-Navarro et al.,2020) and up to 18% of the deaths among children under 5 years of age.展开更多
本文报道了1例早产儿先天性结核的诊断及治疗过程。患儿系胎龄29+1周阴道娩出,生后立即收入武汉大学中南医院新生儿重症监护室(neonatal intensive care unit,NICU)负压隔离病房单独隔离。患儿母亲自孕15~16周出现低热、咳嗽,产前确诊...本文报道了1例早产儿先天性结核的诊断及治疗过程。患儿系胎龄29+1周阴道娩出,生后立即收入武汉大学中南医院新生儿重症监护室(neonatal intensive care unit,NICU)负压隔离病房单独隔离。患儿母亲自孕15~16周出现低热、咳嗽,产前确诊为“亚急性血行播散型肺结核、结核性脑膜炎”并接受抗结核治疗27天。患儿生后第1天胃液检出少量结核杆菌,痰液检出结核DNA,结核抗体阳性,生后第2天血液标本T-SPOT试验阳性。入院后置负压病房隔离,予以呼吸及营养支持等治疗,生后第2天开始予以异烟肼、利福平、吡嗪酰胺三联抗结核治疗。患儿病情逐渐好转,未出现结核感染的严重症状,于生后第52天(纠正胎龄36^(+4)周)离氧出院,现持续随访中。对疑似先天性结核感染的新生儿,及早诊断和规范化治疗可避免不必要的死亡和残疾发生。展开更多
文摘Objective To know the growth of the cerebellum in newborn infants. Methods The centraivermian area (CVA) of the cerebellum was measured by head ultrasonography in 90 newborns including 65full - terms, 14 preterms and 11 small for gestational age infants (SGA). Results The average age of the newborninfants were 4.7d (3~7d). The mean CVA in full-terms was 5.81±0.8cm2, which was significantly greater thanthat in preterms (3.7±1.0cm2), and SGA (5.1±0.8cm2), respectively. However, when corrected for birth weight(BW), the ratio of CVA/BW in term SGA was 2.07, being signoficantly higher than the ratio of 1.72 in normalfull- term newborns. There was no dillerence between male and female infants. Statistically significantrelationships were lound between CVA and BW (r=0.8129, P<0.01) and between CVA and gestational age(r=0.7450, P<0.01). Conclusion The study provide some understanding on the grouth of the cerebellum, and thecerebellar measurement by cranial ultrasound is helpful for the assessment of neurological maturation in newborninfants.
文摘The prefrontal cortex of a human full termnewborn infant just after accidental death was studies by mcans of immunocytochemical technique with antibody directedagainst GABA(Immunonuclear Corp.)and ABC kit(Vector)。GABA-containing neurons were found over all layers and all were nonpyramidal cells.The laminar distribution of GABA-containing ne-urons was not even between different layers,density in laye Ⅱ was prominently higher than any other layers,density in layer Ⅲ and layer Ⅳ was higher than that in layer V and Ⅵ.
基金supported by the following funds:To PAM:predoctoral fellowship.Instituto de Investigacion Biomedica de la Provincia de Cadiz (INIBICA)To MGA:Agencia Andaluza del Conocimiento.Proyectos I+D+I—Programa Operativo FEDER Andalucia 2014-2020 fondos FEDER (SOL2018001071 89-TRA)+1 种基金Agencia Estatal de Investigacion.Ministerio de Educacion y Ciencia.Programa Estatal de Generacion de Conocimiento y Fortalecimiento Cientifico y Tecnologico del Sistema de I+D+i y del Programa Estatal de I+D+i Orientada a los Retos de la Sociedaddel Plan Estatal de Investigacion Cientifica y Tecnica y de Innovacion 2017-2020 (PID2020-115499RB-I00/AEI/10.13039/501100011033)。
文摘There are around 15 million preterm newborns(PT) eve ry year(Atienza-Navarro et al., 2020).With these figures in mind,prematurity represents a major health problem worldwide and it is a leading cause of infant mortality,accounting for up to 35%of all deaths among newborns(Atienza-Navarro et al.,2020) and up to 18% of the deaths among children under 5 years of age.
文摘本文报道了1例早产儿先天性结核的诊断及治疗过程。患儿系胎龄29+1周阴道娩出,生后立即收入武汉大学中南医院新生儿重症监护室(neonatal intensive care unit,NICU)负压隔离病房单独隔离。患儿母亲自孕15~16周出现低热、咳嗽,产前确诊为“亚急性血行播散型肺结核、结核性脑膜炎”并接受抗结核治疗27天。患儿生后第1天胃液检出少量结核杆菌,痰液检出结核DNA,结核抗体阳性,生后第2天血液标本T-SPOT试验阳性。入院后置负压病房隔离,予以呼吸及营养支持等治疗,生后第2天开始予以异烟肼、利福平、吡嗪酰胺三联抗结核治疗。患儿病情逐渐好转,未出现结核感染的严重症状,于生后第52天(纠正胎龄36^(+4)周)离氧出院,现持续随访中。对疑似先天性结核感染的新生儿,及早诊断和规范化治疗可避免不必要的死亡和残疾发生。
